Abstract:
:Multi-drug-resistant tuberculosis (MDR-TB) is a major public-health problem, because treatment is complicated and patients remain infectious for months or years, despite receiving the best available therapy. To gain better understanding of MDR-TB, a retrospective study was initiated to determine the level of drug resistance among patients in a chest-disease institute in India. Two hundred and sixty-three isolates from treatment-failure pulmonary tuberculosis patients (20-70 years) were studied. Drug-sensitivity testing was performed by the modified-proportion method. First- and second-line drugs, along with two quinolone drugs (ofloxacin and ciprofloxacin), were tested. Patients included in this study did not improve with therapy; however, 151 isolates (57.5 %) were susceptible to all four first-line antituberculosis drugs. This study reports low resistance to fluoroquinolones among the strains present in these patients.
journal_name
J Med Microbioljournal_title
Journal of medical microbiologyauthors
Dam T,Isa M,Bose Mdoi
10.1099/jmm.0.45635-0keywords:
subject
Has Abstractpub_date
2005-03-01 00:00:00pages
269-271issue
Pt 3eissn
0022-2615issn
1473-5644journal_volume
54pub_type
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