Cellobiohydrolase 1 from Trichoderma reesei degrades cellulose in single cellobiose steps.

abstract：:Topologically protected pseudospin transport, analogous to the quantum spin Hall effect, cannot be strictly implemented for photons and in general bosons because of the lack of symmetry-protected pseudospins. Here we show that the required protection can be provided by the real-space topological excitation of an inter...

journal_title：Nature communications

authors： Bleu O,Malpuech G,Solnyshkov DD

更新日期：2018-09-28 00:00:00

abstract：:Large single-crystal graphene is highly desired and important for the applications of graphene in electronics, as grain boundaries between graphene grains markedly degrade its quality and properties. Here we report the growth of millimetre-sized hexagonal single-crystal graphene and graphene films joined from such gra...

journal_title：Nature communications

authors： Gao L,Ren W,Xu H,Jin L,Wang Z,Ma T,Ma LP,Zhang Z,Fu Q,Peng LM,Bao X,Cheng HM

更新日期：2012-02-28 00:00:00

abstract：:Naturally occurring single crystals having a multidomain morphology are a counterintuitive phenonomon: the macroscopic appearance is expected to follow the symmetry of the unit cell. Growing such crystals in the lab is a great challenge, especially from organic molecules. We achieve here uniform metallo-organic crysta...

journal_title：Nature communications

authors： di Gregorio MC,Shimon LJW,Brumfeld V,Houben L,Lahav M,van der Boom ME

更新日期：2020-01-20 00:00:00

abstract：:Memory metamaterials are artificial media that sustain transformed electromagnetic properties without persistent external stimuli. Previous memory metamaterials were realized with phase-change materials, such as vanadium dioxide or chalcogenide glasses, which exhibit memory behaviour with respect to electrically/optic...

journal_title：Nature communications

authors： Kim WY,Kim HD,Kim TT,Park HS,Lee K,Choi HJ,Lee SH,Son J,Park N,Min B

更新日期：2016-01-27 00:00:00

abstract：:Nucleosomes containing the histone H3 variant CENP-A are the epigenetic mark of centromeres, the kinetochore assembly sites required for chromosome segregation. HJURP is the CENP-A chaperone, which associates with Mis18α, Mis18β, and M18BP1 to target centromeres and deposit new CENP-A. How these proteins interact to p...

journal_title：Nature communications

authors： Pan D,Walstein K,Take A,Bier D,Kaiser N,Musacchio A

更新日期：2019-09-06 00:00:00

abstract：:The amazing structural variety of cells is matched only by their functional diversity, and reflects the complex interplay between biochemical and mechanical regulation. How both regulatory layers generate specifically shaped cellular domains is not fully understood. Here, we report how cell growth domains are shaped i...

journal_title：Nature communications

authors： Abenza JF,Couturier E,Dodgson J,Dickmann J,Chessel A,Dumais J,Salas REC

更新日期：2015-10-12 00:00:00

abstract：:Plasma membrane Ca2+-ATPases (PMCAs) are key regulators of global Ca2+ homeostasis and local intracellular Ca2+ dynamics. Recently, Neuroplastin (NPTN) and basigin were identified as previously unrecognized obligatory subunits of PMCAs that dramatically increase the efficiency of PMCA-mediated Ca2+ clearance. Here, we...

journal_title：Nature communications

authors： Gong D,Chi X,Ren K,Huang G,Zhou G,Yan N,Lei J,Zhou Q

更新日期：2018-09-06 00:00:00

abstract：:Replication of mammalian mitochondrial DNA (mtDNA) is an essential process that requires high fidelity and control at multiple levels to ensure proper mitochondrial function. Mutations in the mitochondrial genome maintenance exonuclease 1 (MGME1) gene were recently reported in mitochondrial disease patients. Here, to ...

journal_title：Nature communications

authors： Matic S,Jiang M,Nicholls TJ,Uhler JP,Dirksen-Schwanenland C,Polosa PL,Simard ML,Li X,Atanassov I,Rackham O,Filipovska A,Stewart JB,Falkenberg M,Larsson NG,Milenkovic D

更新日期：2018-03-23 00:00:00

abstract：:CD24 is overexpressed in nearly 70% human cancers, whereas TP53 is the most frequently mutated tumour-suppressor gene that functions in a context-dependent manner. Here we show that both targeted mutation and short hairpin RNA (shRNA) silencing of CD24 retard the growth, progression and metastasis of prostate cancer. ...

journal_title：Nature communications

authors： Wang L,Liu R,Ye P,Wong C,Chen GY,Zhou P,Sakabe K,Zheng X,Wu W,Zhang P,Jiang T,Bassetti MF,Jube S,Sun Y,Zhang Y,Zheng P,Liu Y

更新日期：2015-01-20 00:00:00

abstract：:The manipulation of crystal orientation from the thermodynamic equilibrium states is desired in layered hybrid perovskite films to direct charge transport and enhance the perovskite devices performance. Here we report a templated growth mechanism of layered perovskites from 3D-like perovskites which can be a general d...

journal_title：Nature communications

authors： Wang J,Luo S,Lin Y,Chen Y,Deng Y,Li Z,Meng K,Chen G,Huang T,Xiao S,Huang H,Zhou C,Ding L,He J,Huang J,Yuan Y

更新日期：2020-01-29 00:00:00

abstract：:Although multiphoton-pumped lasing from a solution of chromophores is important in the emerging fields of nonlinear optofluidics and bio-photonics, conventionally used organic dyes are often rendered unsuitable because of relatively small multiphoton absorption cross-sections and low photostability. Here, we demonstra...

journal_title：Nature communications

authors： Li M,Zhi M,Zhu H,Wu WY,Xu QH,Jhon MH,Chan Y

更新日期：2015-09-30 00:00:00

abstract：:Device performance and in particular device stability for blue perovskite light-emitting diodes (PeLEDs) remain considerable challenges for the whole community. In this manuscript, we conceive an approach by tuning the 'A-site' cation composition of perovskites to develop blue-emitters. We herein report a Rubidium-Ces...

journal_title：Nature communications

authors： Jiang Y,Qin C,Cui M,He T,Liu K,Huang Y,Luo M,Zhang L,Xu H,Li S,Wei J,Liu Z,Wang H,Kim GH,Yuan M,Chen J

更新日期：2019-04-23 00:00:00

abstract：:Topological nodal line semimetals, a novel quantum state of materials, possess topologically nontrivial valence and conduction bands that touch at a line near the Fermi level. The exotic band structure can lead to various novel properties, such as long-range Coulomb interaction and flat Landau levels. Recently, topolo...

journal_title：Nature communications

authors： Feng B,Fu B,Kasamatsu S,Ito S,Cheng P,Liu CC,Feng Y,Wu S,Mahatha SK,Sheverdyaeva P,Moras P,Arita M,Sugino O,Chiang TC,Shimada K,Miyamoto K,Okuda T,Wu K,Chen L,Yao Y,Matsuda I

更新日期：2017-10-18 00:00:00

abstract：:We developed a computer-aided analysis tool for quantitatively determining bioluminescent reporter distributions inside small animals. The core innovations are a body-fitting animal shuttle and a statistical mouse atlas, both of which are spatially aligned and scaled according to the animal's weight, and hence provide...

journal_title：Nature communications

authors： Klose AD,Paragas N

更新日期：2018-10-15 00:00:00

abstract：:Over the recent decades there has been tremendous progress in understanding and controlling friction between surfaces in relative motion. However the complex nature of the involved processes has forced most of this work to be of rather empirical nature. Two very distinctive physical systems, hard two-dimensional layer...

journal_title：Nature communications

authors： Vanossi A,Bechinger C,Urbakh M

更新日期：2020-09-16 00:00:00

abstract：:Pupylation is a posttranslational protein modification occurring in mycobacteria and other actinobacteria that is functionally analogous to ubiquitination. Here we report the crystal structures of the modification enzymes involved in this pathway, the prokaryotic ubiquitin-like protein (Pup) ligase PafA and the depupy...

journal_title：Nature communications

authors： Özcelik D,Barandun J,Schmitz N,Sutter M,Guth E,Damberger FF,Allain FH,Ban N,Weber-Ban E

更新日期：2012-01-01 00:00:00

abstract：:The myogenic regulatory factor MRF4 is highly expressed in adult skeletal muscle but its function is unknown. Here we show that Mrf4 knockdown in adult muscle induces hypertrophy and prevents denervation-induced atrophy. This effect is accompanied by increased protein synthesis and widespread activation of muscle-spec...

journal_title：Nature communications

authors： Moretti I,Ciciliot S,Dyar KA,Abraham R,Murgia M,Agatea L,Akimoto T,Bicciato S,Forcato M,Pierre P,Uhlenhaut NH,Rigby PW,Carvajal JJ,Blaauw B,Calabria E,Schiaffino S

更新日期：2016-08-03 00:00:00

abstract：:The Earth's biggest magmatic events are believed to originate from massive melting when hot mantle plumes rising from the lowermost mantle reach the base of the lithosphere. Classical models predict large plume heads that cause kilometre-scale surface uplift, and narrow (100 km radius) plume tails that remain in the m...

journal_title：Nature communications

authors： Dannberg J,Sobolev SV

更新日期：2015-04-24 00:00:00

abstract：:Conventional implementations of two-dimensional electronic spectroscopy typically spatially average over ~1010 chromophores spread over ~104 micron square area, limiting their ability to characterize spatially heterogeneous samples. Here we present a variation of two-dimensional electronic spectroscopy that is capable...

journal_title：Nature communications

authors： Tiwari V,Matutes YA,Gardiner AT,Jansen TLC,Cogdell RJ,Ogilvie JP

更新日期：2018-10-11 00:00:00

abstract：:Structural DNA nanotechnology seeks to build synthetic molecular machinery from DNA. DNA nanomachines are artificially designed assemblies that switch between defined conformations in response to an external cue. Though it has proved possible to create DNA machines and rudimentary walkers, the function of such autonom...

journal_title：Nature communications

authors： Surana S,Bhat JM,Koushika SP,Krishnan Y

更新日期：2011-06-07 00:00:00

abstract：:Chaperone-mediated autophagy (CMA) is a selective mechanism for the degradation of soluble proteins in lysosomes. CMA contributes to cellular quality control and is activated as part of the cellular response to different stressors. Defective CMA has been identified in ageing and different age-related diseases. Until n...

journal_title：Nature communications

authors： Koga H,Martinez-Vicente M,Macian F,Verkhusha VV,Cuervo AM

更新日期：2011-07-12 00:00:00

abstract：:In quantizing magnetic fields, graphene superlattices exhibit a complex fractal spectrum often referred to as the Hofstadter butterfly. It can be viewed as a collection of Landau levels that arise from quantization of Brown-Zak minibands recurring at rational (p/q) fractions of the magnetic flux quantum per superlatti...

journal_title：Nature communications

authors： Barrier J,Kumaravadivel P,Krishna Kumar R,Ponomarenko LA,Xin N,Holwill M,Mullan C,Kim M,Gorbachev RV,Thompson MD,Prance JR,Taniguchi T,Watanabe K,Grigorieva IV,Novoselov KS,Mishchenko A,Fal'ko VI,Geim AK,Berdyugin AI

更新日期：2020-11-13 00:00:00

abstract：:While plasmonic designs have dominated recent trends in structural color, schemes using localized surface plasmon resonances and surface plasmon polaritons that simultaneously achieve high color vibrancy at ultrahigh resolution have been elusive because of tradeoffs between size and performance. Herein we demonstrate ...

journal_title：Nature communications

authors： Lee JS,Park JY,Kim YH,Jeon S,Ouellette O,Sargent EH,Kim DH,Hyun JK

更新日期：2019-10-21 00:00:00

abstract：:Tropical carbon emissions are largely derived from direct forest clearing processes. Yet, emissions from drought-induced forest fires are, usually, not included in national-level carbon emission inventories. Here we examine Brazilian Amazon drought impacts on fire incidence and associated forest fire carbon emissions ...

journal_title：Nature communications

authors： Aragão LEOC,Anderson LO,Fonseca MG,Rosan TM,Vedovato LB,Wagner FH,Silva CVJ,Silva Junior CHL,Arai E,Aguiar AP,Barlow J,Berenguer E,Deeter MN,Domingues LG,Gatti L,Gloor M,Malhi Y,Marengo JA,Miller JB,Phillips OL,Sa

更新日期：2018-02-13 00:00:00

abstract：:The alloy-design strategy of combining multiple elements in near-equimolar ratios has shown great potential for producing exceptional engineering materials, often known as 'high-entropy alloys'. Understanding the elemental distribution, and, thus, the evolution of the configurational entropy during solidification, is ...

journal_title：Nature communications

authors： Santodonato LJ,Zhang Y,Feygenson M,Parish CM,Gao MC,Weber RJ,Neuefeind JC,Tang Z,Liaw PK

更新日期：2015-01-20 00:00:00

abstract：:Orexins are associated with drug relapse in rodents. Here, we show that acute restraint stress in mice activates lateral hypothalamic (LH) orexin neurons, increases levels of orexin A and 2-arachidonoylglycerol (2-AG) in the ventral tegmental area (VTA), and reinstates extinguished cocaine-conditioned place preference...

journal_title：Nature communications

authors： Tung LW,Lu GL,Lee YH,Yu L,Lee HJ,Leishman E,Bradshaw H,Hwang LL,Hung MS,Mackie K,Zimmer A,Chiou LC

更新日期：2016-07-22 00:00:00

abstract：:Analyzing scattered wave to recognize object is of fundamental significance in wave physics. Recently-emerged deep learning technique achieved great success in interpreting wave field such as in ultrasound non-destructive testing and disease diagnosis, but conventionally need time-consuming computer postprocessing or ...

journal_title：Nature communications

authors： Weng J,Ding Y,Hu C,Zhu XF,Liang B,Yang J,Cheng J

更新日期：2020-12-09 00:00:00

abstract：:Topologically nontrivial materials host protected edge states associated with the bulk band inversion through the bulk-edge correspondence. Manipulating such edge states is highly desired for developing new functions and devices practically using their dissipation-less nature and spin-momentum locking. Here we introdu...

journal_title：Nature communications

authors： Mitsuishi N,Sugita Y,Bahramy MS,Kamitani M,Sonobe T,Sakano M,Shimojima T,Takahashi H,Sakai H,Horiba K,Kumigashira H,Taguchi K,Miyamoto K,Okuda T,Ishiwata S,Motome Y,Ishizaka K

更新日期：2020-05-18 00:00:00

abstract：:Patterns in biomass production are determined by resource input (productivity) and trophic transfer efficiency. At fixed resource input, variation in consumer biomass production has been related to food quality, metabolic type and diversity among species. In contrast, intraspecific variation in individual body size be...

journal_title：Nature communications

authors： Reichstein B,Persson L,De Roos AM

更新日期：2015-03-04 00:00:00

abstract：:The respiratory chain in mitochondria is composed of membrane-bound proteins that couple electron transfer to proton translocation across the inner membrane. These charge-transfer reactions are regulated by the proton electrochemical gradient that is generated and maintained by the transmembrane charge transfer. Here,...

journal_title：Nature communications

authors： Björck ML,Brzezinski P

更新日期：2018-08-09 00:00:00