Graphene liquid crystal retarded percolation for new high-k materials.

abstract：:Propagation behaviors of electromagnetic waves are governed by the equifrequency surface of the medium. Up to now, ordinary materials, including the medium exist in nature and the man-made metamaterials, always have an equifrequency surface (ellipsoid or hyperboloid) centered at zero k-point. Here we propose a new typ...

journal_title：Nature communications

authors： Chen WJ,Hou B,Zhang ZQ,Pendry JB,Chan CT

更新日期：2018-05-25 00:00:00

abstract：:Normalization is a common cortical computation widely observed in sensory perception, but its importance in perception of reward value and decision making remains largely unknown. We examined (1) whether normalized value signals occur in the orbitofrontal cortex (OFC) and (2) whether changes in behavioral task context...

journal_title：Nature communications

authors： Yamada H,Louie K,Tymula A,Glimcher PW

更新日期：2018-01-11 00:00:00

abstract：:Time-resolved photoelectron spectroscopy (TRPES) is a useful approach to elucidate the coupled electronic-nuclear quantum dynamics underlying chemical processes, but has remained limited by the use of low photon energies. Here, we demonstrate the general advantages of XUV-TRPES through an application to NO2, one of th...

journal_title：Nature communications

authors： von Conta A,Tehlar A,Schletter A,Arasaki Y,Takatsuka K,Wörner HJ

更新日期：2018-08-08 00:00:00

abstract：:Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive analytical technique with molecular specificity, making it an ideal candidate for therapeutic drug monitoring (TDM). However, in critical diagnostic media including blood, nonspecific protein adsorption coupled with weak surface affinities and small Raman...

journal_title：Nature communications

authors： Sun F,Hung HC,Sinclair A,Zhang P,Bai T,Galvan DD,Jain P,Li B,Jiang S,Yu Q

更新日期：2016-11-11 00:00:00

abstract：:Making decisions based on choice-outcome history is a crucial, adaptive ability in life. However, the neural circuit mechanisms underlying history-dependent decision-making are poorly understood. In particular, history-related signals have been found in many brain areas during various decision-making tasks, but the ca...

journal_title：Nature communications

authors： Hwang EJ,Dahlen JE,Mukundan M,Komiyama T

更新日期：2017-11-01 00:00:00

abstract：:Pathological amino-acid substitutions in the amyloid precursor protein (APP) and chemical γ-secretase modulators affect the processing of APP by the γ-secretase complex and the production of the amyloid-beta peptide Aβ42, the accumulation of which is considered causative of Alzheimer's disease. Here we demonstrate tha...

journal_title：Nature communications

authors： Dimitrov M,Alattia JR,Lemmin T,Lehal R,Fligier A,Houacine J,Hussain I,Radtke F,Dal Peraro M,Beher D,Fraering PC

更新日期：2013-01-01 00:00:00

abstract：:Nanoparticles hosted in conductive matrices are ubiquitous in electrochemical energy storage, catalysis and energetic devices. However, agglomeration and surface oxidation remain as two major challenges towards their ultimate utility, especially for highly reactive materials. Here we report uniformly distributed nanop...

journal_title：Nature communications

authors： Chen Y,Egan GC,Wan J,Zhu S,Jacob RJ,Zhou W,Dai J,Wang Y,Danner VA,Yao Y,Fu K,Wang Y,Bao W,Li T,Zachariah MR,Hu L

更新日期：2016-08-12 00:00:00

abstract：:Mitochondria and peroxisomes proliferate by division. During division, a part of their membrane is pinched off by constriction of the ring-shaped mitochondrial division (MD) and peroxisome-dividing (POD) machinery. This constriction is mediated by a dynamin-like GTPase Dnm1 that requires a large amount of GTP as an en...

journal_title：Nature communications

authors： Imoto Y,Abe Y,Honsho M,Okumoto K,Ohnuma M,Kuroiwa H,Kuroiwa T,Fujiki Y

更新日期：2018-11-06 00:00:00

abstract：:The role of microglia in spinal cord injury (SCI) remains poorly understood and is often confused with the response of macrophages. Here, we use specific transgenic mouse lines and depleting agents to understand the response of microglia after SCI. We find that microglia are highly dynamic and proliferate extensively ...

journal_title：Nature communications

authors： Bellver-Landete V,Bretheau F,Mailhot B,Vallières N,Lessard M,Janelle ME,Vernoux N,Tremblay MÈ,Fuehrmann T,Shoichet MS,Lacroix S

更新日期：2019-01-31 00:00:00

abstract：:Myelin, rather than being a static insulator of axons, is emerging as an active participant in circuit plasticity. This requires precise regulation of oligodendrocyte numbers and myelination patterns. Here, by devising a laser ablation approach of single oligodendrocytes, followed by in vivo imaging and correlated ult...

journal_title：Nature communications

authors： Snaidero N,Schifferer M,Mezydlo A,Zalc B,Kerschensteiner M,Misgeld T

更新日期：2020-09-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Giulimondi F,Digiacomo L,Pozzi D,Palchetti S,Vulpis E,Capriotti AL,Chiozzi RZ,Laganà A,Amenitsch H,Masuelli L,Peruzzi G,Mahmoudi M,Screpanti I,Zingoni A,Caracciolo G

更新日期：2020-03-31 00:00:00

abstract：:Pompe disease, a rare lysosomal storage disease caused by deficiency of the lysosomal acid α-glucosidase (GAA), is characterized by glycogen accumulation, triggering severe secondary cellular damage and resulting in progressive motor handicap and premature death. Numerous disease-causing mutations in the gaa gene have...

journal_title：Nature communications

authors： Roig-Zamboni V,Cobucci-Ponzano B,Iacono R,Ferrara MC,Germany S,Bourne Y,Parenti G,Moracci M,Sulzenbacher G

更新日期：2017-10-24 00:00:00

abstract：:Orexins are associated with drug relapse in rodents. Here, we show that acute restraint stress in mice activates lateral hypothalamic (LH) orexin neurons, increases levels of orexin A and 2-arachidonoylglycerol (2-AG) in the ventral tegmental area (VTA), and reinstates extinguished cocaine-conditioned place preference...

journal_title：Nature communications

authors： Tung LW,Lu GL,Lee YH,Yu L,Lee HJ,Leishman E,Bradshaw H,Hwang LL,Hung MS,Mackie K,Zimmer A,Chiou LC

更新日期：2016-07-22 00:00:00

abstract：:Although soluble inhibitors are frequently used to block cell binding to the extracellular matrix (ECM), mechanical stretching of a protein fibre alone can physically destroy a cell-binding site. Here, we show using binding assays and steered molecular dynamics that mechanical tension along fibronectin (Fn) fibres cau...

journal_title：Nature communications

authors： Chabria M,Hertig S,Smith ML,Vogel V

更新日期：2010-01-01 00:00:00

abstract：:Optimal decision-making employs short-term rewards and abstract long-term information based on which of these is deemed relevant. Employing short- vs. long-term information is associated with different learning mechanisms, yet neural evidence showing that these two are dissociable is lacking. Here we demonstrate that ...

journal_title：Nature communications

authors： Fischer AG,Bourgeois-Gironde S,Ullsperger M

更新日期：2017-11-22 00:00:00

abstract：:Emphysema is one of the disease conditions that comprise chronic obstructive pulmonary disease. Prothymosin α transgenic mice exhibit an emphysema phenotype, but the pathophysiological role of prothymosin α in emphysema remains unclear. Here we show that prothymosin α contributes to the pathogenesis of emphysema by in...

journal_title：Nature communications

authors： Su BH,Tseng YL,Shieh GS,Chen YC,Shiang YC,Wu P,Li KJ,Yen TH,Shiau AL,Wu CL

更新日期：2013-01-01 00:00:00

abstract：:Xylanolytic enzymes from glycoside hydrolase family 43 (GH43) are involved in the breakdown of hemicellulose, the second most abundant carbohydrate in plants. Here, we kinetically and mechanistically describe the non-reducing-end xylose-releasing exo-oligoxylanase activity and report the crystal structure of a native ...

journal_title：Nature communications

authors： Morais MAB,Coines J,Domingues MN,Pirolla RAS,Tonoli CCC,Santos CR,Correa JBL,Gozzo FC,Rovira C,Murakami MT

更新日期：2021-01-14 00:00:00

abstract：:The separation of immiscible liquids has significant implications for magma evolution and the formation of magmatic ore deposits. We combine high-resolution imaging and electron probe microanalysis with the first use of atom probe tomography on tholeiitic basaltic glass from Hawaii, the Snake River Plain, and Iceland,...

journal_title：Nature communications

authors： Honour VC,Holness MB,Charlier B,Piazolo SC,Namur O,Prosa TJ,Martin I,Helz RT,Maclennan J,Jean MM

更新日期：2019-10-23 00:00:00

abstract：:1T-MoS2 and single-atom modified analogues represent a highly promising class of low-cost catalysts for hydrogen evolution reaction (HER). However, the role of single atoms, either as active species or promoters, remains vague despite its essentiality toward more efficient HER. In this work, we report the unambiguous ...

journal_title：Nature communications

authors： Pattengale B,Huang Y,Yan X,Yang S,Younan S,Hu W,Li Z,Lee S,Pan X,Gu J,Huang J

更新日期：2020-08-17 00:00:00

abstract：:Recent advances in nonlinear optics have revolutionized integrated photonics, providing on-chip solutions to a wide range of new applications. Currently, state of the art integrated nonlinear photonic devices are mainly based on dielectric material platforms, such as Si3N4 and SiO2. While semiconductor materials featu...

journal_title：Nature communications

authors： Chang L,Xie W,Shu H,Yang QF,Shen B,Boes A,Peters JD,Jin W,Xiang C,Liu S,Moille G,Yu SP,Wang X,Srinivasan K,Papp SB,Vahala K,Bowers JE

更新日期：2020-03-12 00:00:00

abstract：:Selector devices are indispensable components of large-scale nonvolatile memory and neuromorphic array systems. Besides the conventional silicon transistor, two-terminal ovonic threshold switching device with much higher scalability is currently the most industrially favored selector technology. However, current ovoni...

journal_title：Nature communications

authors： Jia S,Li H,Gotoh T,Longeaud C,Zhang B,Lyu J,Lv S,Zhu M,Song Z,Liu Q,Robertson J,Liu M

更新日期：2020-09-15 00:00:00

abstract：:Removal of internal transcribed spacer 2 (ITS2) from pre-ribosomal RNA is essential to make functional ribosomes. This complicated processing reaction begins with a single endonucleolytic cleavage followed by exonucleolytic trimming at both new cleavage sites to generate mature 5.8S and 25S rRNA. We reconstituted the ...

journal_title：Nature communications

authors： Fromm L,Falk S,Flemming D,Schuller JM,Thoms M,Conti E,Hurt E

更新日期：2017-11-27 00:00:00

abstract：:The formation of two triplet excitons at the cost of one photon via singlet exciton fission in organic semiconductors can potentially enhance the photocurrent in photovoltaic devices. However, the role of spin density distribution in driving this photophysical process has been unclear until now. Here we present the si...

journal_title：Nature communications

authors： Krishnapriya KC,Roy P,Puttaraju B,Salzner U,Musser AJ,Jain M,Dasgupta J,Patil S

更新日期：2019-01-03 00:00:00

abstract：:Synonymous mutations have been viewed as silent mutations, since they only affect the DNA and mRNA, but not the amino acid sequence of the resulting protein. Nonetheless, recent studies suggest their significant impact on splicing, RNA stability, RNA folding, translation or co-translational protein folding. Hence, we ...

journal_title：Nature communications

authors： Sharma Y,Miladi M,Dukare S,Boulay K,Caudron-Herger M,Groß M,Backofen R,Diederichs S

更新日期：2019-06-12 00:00:00

abstract：:In patients with damage to the primary visual cortex (V1), residual vision can guide goal-directed movements to targets in the blind field without awareness. This phenomenon has been termed blindsight, and its neural mechanisms are controversial. There should be visual pathways to the higher visual cortices bypassing ...

journal_title：Nature communications

authors： Kinoshita M,Kato R,Isa K,Kobayashi K,Kobayashi K,Onoe H,Isa T

更新日期：2019-01-11 00:00:00

abstract：:Mutant p53s (mutp53) increase cancer invasiveness by upregulating Rab-coupling protein (RCP) and diacylglycerol kinase-α (DGKα)-dependent endosomal recycling. Here we report that mutp53-expressing tumour cells produce exosomes that mediate intercellular transfer of mutp53's invasive/migratory gain-of-function by incre...

journal_title：Nature communications

authors： Novo D,Heath N,Mitchell L,Caligiuri G,MacFarlane A,Reijmer D,Charlton L,Knight J,Calka M,McGhee E,Dornier E,Sumpton D,Mason S,Echard A,Klinkert K,Secklehner J,Kruiswijk F,Vousden K,Macpherson IR,Blyth K,Bailey P,

更新日期：2018-11-29 00:00:00

abstract：:In social species, the phenotype and fitness of an individual depend in part on the genotype of its social partners. However, how these indirect genetic effects affect genotype fitness in competitive situations is poorly understood in animal societies. We therefore studied phenotypic plasticity and fitness of two clon...

journal_title：Nature communications

authors： Teseo S,Châline N,Jaisson P,Kronauer DJ

更新日期：2014-01-01 00:00:00

abstract：:The Paris Agreement set a goal to keep global warming well below 2 °C and pursue efforts to limit it to 1.5 °C. Understanding how 0.5 °C less warming reduces impacts and risks is key for climate policies. Here, we show that both areal and population exposures to dangerous extreme precipitation events (e.g., once in 10...

journal_title：Nature communications

authors： Zhang W,Zhou T,Zou L,Zhang L,Chen X

更新日期：2018-08-08 00:00:00

abstract：:The RNA-binding protein Roquin is required to prevent autoimmunity. Roquin controls T-helper cell activation and differentiation by limiting the induced expression of costimulatory receptors such as tumor necrosis factor receptor superfamily 4 (Tnfrs4 or Ox40). A constitutive decay element (CDE) with a characteristic ...

journal_title：Nature communications

authors： Janowski R,Heinz GA,Schlundt A,Wommelsdorf N,Brenner S,Gruber AR,Blank M,Buch T,Buhmann R,Zavolan M,Niessing D,Heissmeyer V,Sattler M

更新日期：2016-03-24 00:00:00

abstract：:Here we benchmark device-to-device variation in field-effect transistors (FETs) based on monolayer MoS2 and WS2 films grown using metal-organic chemical vapor deposition process. Our study involves 230 MoS2 FETs and 160 WS2 FETs with channel lengths ranging from 5 μm down to 100 nm. We use statistical measures to eval...

journal_title：Nature communications

authors： Sebastian A,Pendurthi R,Choudhury TH,Redwing JM,Das S

更新日期：2021-01-29 00:00:00