Loss of CD47 Makes Dendritic Cells See Red.

Abstract:

:Whereas dendritic cells (DCs) can be activated in many ways to trigger immunity, hardly anything is known about the mechanisms that counterbalance DC activation. Cyster and colleagues now demonstrate that the "self" molecule CD47 on erythrocytes critically restricts splenic DC activation.

journal_name

Immunity

journal_title

Immunity

authors

van den Berg TK,van Bruggen R

doi

10.1016/j.immuni.2015.09.008

subject

Has Abstract

pub_date

2015-10-20 00:00:00

pages

622-4

issue

4

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(15)00393-3

journal_volume

43

pub_type

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