Current-limiting challenges for all-spin logic devices.

abstract：:Fatigue is a very common non-motor symptom in Parkinson disease (PD) patients. It included physical fatigue and mental fatigue. The potential mechanisms of mental fatigue involving serotonergic dysfunction and abnormal iron metabolism are still unknown. Therefore, we evaluated the fatigue symptoms, classified PD patie...

journal_title：Scientific reports

authors： Zuo LJ,Yu SY,Hu Y,Wang F,Piao YS,Lian TH,Yu QJ,Wang RD,Li LX,Guo P,Du Y,Zhu RY,Jin Z,Wang YJ,Wang XM,Chan P,Chen SD,Wang YJ,Zhang W

更新日期：2016-12-21 00:00:00

abstract：:Mechanistic studies of deregulated ERG in prostate cancer and other cancers continue to enhance its role in cancer biology and its utility as a biomarker and therapeutic target. Here, we show that ERG, through its physical interaction with androgen receptor, induces AR aggregation and endoplasmic reticulum stress in t...

journal_title：Scientific reports

authors： Sreenath TL,Macalindong SS,Mikhalkevich N,Sharad S,Mohamed A,Young D,Borbiev T,Xavier C,Gupta R,Jamal M,Babcock K,Tan SH,Nevalainen MT,Dobi A,Petrovics G,Sesterhenn IA,Rosner IL,Bieberich CJ,Nelson P,Vasioukhin V,

更新日期：2017-04-24 00:00:00

abstract：:Sacha inchi (Plukenetia volubilis L.) is a shrub native to Amazon rainforests that's of commercial interest as its seeds contain 35-60% edible oil (dry weight). This oil is one of the healthiest vegetable oils due to its high polyunsaturated fatty acid content and favourable ratio of omega-6 to omega-3 fatty acids. De...

journal_title：Scientific reports

authors： Liu G,Wu Z,Peng Y,Shang X,Xie Y,Arnold RJ

更新日期：2020-11-24 00:00:00

abstract：:Enhanced and immediate expression of cyclooxygenase-2 (COX-2) mRNA is observed in IL-1β-stimulated OA chondrocytes but the synthesis of protein found significantly delayed. Here we investigated the role of stress granules (SGs), ribonucleoprotein complexes that regulate mRNA translation, in the delayed translation of ...

journal_title：Scientific reports

authors： Ansari MY,Haqqi TM

更新日期：2016-06-08 00:00:00

abstract：:Here we developed an orange light-absorbing chromoprotein named ShadowR as a novel acceptor for performing fluorescence lifetime imaging microscopy-based Förster resonance energy transfer (FLIM-FRET) measurement in living cells. ShadowR was generated by replacing hydrophobic amino acids located at the surface of the c...

journal_title：Scientific reports

authors： Murakoshi H,Horiuchi H,Kosugi T,Onda M,Sato A,Koga N,Nabekura J

更新日期：2019-08-19 00:00:00

abstract：:New vaccine production technologies can significantly shorten the timelines for availability of a strain-specific vaccine in the event of an influenza pandemic. We sought to evaluate the potential benefits of early vaccination in reducing the clinical attack rate (CAR), taking into account the timing and speed of vacc...

journal_title：Scientific reports

authors： Champredon D,Laskowski M,Charland N,Moghadas SM

更新日期：2018-04-24 00:00:00

abstract：:Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polyp...

journal_title：Scientific reports

authors： Matsumoto H,Hoshino J,Arai Y,Mukai R,Nakamura K,Kikuchi Y,Kishi S,Akiyama H

更新日期：2020-11-11 00:00:00

abstract：:The hypothalamic-pituitary-adrenal (HPA) axis is an important component of neuroendocrine stress regulation and coping behavior. Transcriptome profiles of the hypothalamus and adrenal gland were assessed to identify molecular pathways and candidate genes for coping behavior in pigs. Ten each of high- (HR) and low- (LR...

journal_title：Scientific reports

authors： Gley K,Murani E,Trakooljul N,Zebunke M,Puppe B,Wimmers K,Ponsuksili S

更新日期：2019-09-10 00:00:00

abstract：:Seeded polymerisation of proteins forming amyloid fibres and their spread in tissues has been implicated in the pathogenesis of multiple neurodegenerative diseases: so called "prion-like" mechanisms. While ex vivo mammalian prions, composed of multichain assemblies of misfolded host-encoded prion protein (PrP), act as...

journal_title：Scientific reports

authors： Terry C,Harniman RL,Sells J,Wenborn A,Joiner S,Saibil HR,Miles MJ,Collinge J,Wadsworth JDF

更新日期：2019-01-23 00:00:00

abstract：:Next generation sequencing (NGS) together with protein expression analysis is back bone of molecularly targeted therapy in precision medicine. Our retrospective study shows our experience with NGS of 324 genes in combination with protein expression in patients with advanced breast cancer (aBC). The primary purpose was...

journal_title：Scientific reports

authors： Hempel D,Ebner F,Garg A,Trepotec Z,Both A,Stein W,Gaumann A,Güttler L,Janni W,DeGregorio A,Hempel L,Milani V

更新日期：2020-06-26 00:00:00

abstract：:Drought stress and pathogen infection simultaneously occur in the field. In this study, the interaction of these two stresses with chickpea, their individual and combined effect and the net impact on plant growth and yield traits were systematically assessed under field and confined pot experiments. The field experime...

journal_title：Scientific reports

authors： Sinha R,Irulappan V,Mohan-Raju B,Suganthi A,Senthil-Kumar M

更新日期：2019-04-03 00:00:00

abstract：:Paclitaxel drug coated balloons (DCBs) should provide optimal drug transfer exclusively to the target tissue. The aim of this study was to evaluate the particle loss by handling during angioplasty. A robotic arm was developed for systematic and reproducible drug abrasion experiments. The contact force on eight differe...

journal_title：Scientific reports

authors： Heinrich A,Engler MS,Güttler FV,Matthäus C,Popp J,Teichgräber UK

更新日期：2020-10-14 00:00:00

abstract：:Activity-regulated cytoskeleton-associated protein (Arc; also known as Arg3.1) is an immediate early gene product that is transcribed in dendritic spines and, to date, has been best characterized as a positive regulator of AMPAR endocytosis during long-term depression (LTD) through interaction with endocytic proteins....

journal_title：Scientific reports

authors： Goo BMSS,Sanstrum BJ,Holden DZY,Yu Y,James NG

更新日期：2018-10-02 00:00:00

abstract：:Black phosphorus (BP) has recently been rediscovered as a new and interesting two-dimensional material due to its unique electronic and optical properties. Here, we study the linear and nonlinear optical properties of BP flakes. We observe that both the linear and nonlinear optical properties are anisotropic and can b...

journal_title：Scientific reports

authors： Li D,Jussila H,Karvonen L,Ye G,Lipsanen H,Chen X,Sun Z

更新日期：2015-10-30 00:00:00

abstract：:Soil microbial responses to fire are likely to change over the course of forest recovery. Investigations on long-term changes in bacterial dynamics following fire are rare. We characterized the soil bacterial communities across three different times post fire in a 2 to 152-year fire chronosequence by Illumina MiSeq se...

journal_title：Scientific reports

authors： Sun H,Santalahti M,Pumpanen J,Köster K,Berninger F,Raffaello T,Asiegbu FO,Heinonsalo J

更新日期：2016-08-30 00:00:00

abstract：:Several MRI contrast agent clinical formulations are now known to leave deposits of the heavy metal gadolinium in the brain, bones, and other organs of patients. This persistent biological accumulation of gadolinium has been recently recognized as a deleterious outcome in patients administered Gd-based contrast agents...

journal_title：Scientific reports

authors： Rees JA,Deblonde GJ,An DD,Ansoborlo C,Gauny SS,Abergel RJ

更新日期：2018-03-13 00:00:00

abstract：:The roles of CD4 + T cells and CD8 + T cells in hepatitis B virus (HBV) infection have been well documented. However, the role of innate immunity in HBV infection remains obscure. Here we examined the effect of activation of innate immunity by polyinosinic: polycytidylic acid (PolyI:C) on HBV infection. A chronic HBV ...

journal_title：Scientific reports

authors： Tong S,Liu G,Li M,Li X,Liu Q,Peng H,Li S,Ren H,Yin W

更新日期：2017-03-22 00:00:00

abstract：:Highly omnidirectional and frequency controllable carbon/polyaniline (C/PANI)-based, two- (2D) and three-dimensional (3D) monopole antennas were fabricated using screen-printing and a one-step, dimensionally confined hydrothermal strategy, respectively. Solvated C/PANI was synthesized by low-temperature interfacial po...

journal_title：Scientific reports

authors： Shin KY,Kim M,Lee JS,Jang J

更新日期：2015-09-04 00:00:00

abstract：:The concept of remission for patients with inflammatory bowel diseases has recently evolved, and should also include histological healing of the mucosa, difficult to evaluate since there is no agreement on pathological scores and those available are quite complex to use in the daily routine. We evaluated the possible ...

journal_title：Scientific reports

authors： Villanacci V,Antonelli E,Lanzarotto F,Bozzola A,Cadei M,Bassotti G

更新日期：2017-07-28 00:00:00

abstract：:Disease associated genetic variations often cause intracellular enzyme inactivation, dysregulation and instability. However, allosteric communication of mutational effects to distant functional sites leading to loss-of-function remains poorly understood. We characterize here interdomain site-to-site communication by w...

journal_title：Scientific reports

authors： Medina-Carmona E,Neira JL,Salido E,Fuchs JE,Palomino-Morales R,Timson DJ,Pey AL

更新日期：2017-03-14 00:00:00

abstract：:RNaseIII proteins are dsRNA-specific endonucleases involved in many important biological processes, such as small RNA processing and maturation in eukaryotes. Various small RNAs have been identified in a protozoan parasite Entamoeba histolytica. EhRNaseIII is the only RNaseIII endonuclease domain (RIIID)-containing pr...

journal_title：Scientific reports

authors： Yu X,Li X,Zheng L,Ma J,Gan J

更新日期：2017-03-20 00:00:00

abstract：:Patients who undergo total hip arthroplasty (THA) may experience a large amount of blood loss. The objective of our study is to include randomized controlled trials (RCTs) and compare the clinical outcomes of fibrin sealant (FS) versus placebo after a THA. In October 2015, we searched the following databases: Medline,...

journal_title：Scientific reports

authors： Zhao Z,Ma X,Ma J,Sun X,Li F,Lv J

更新日期：2018-01-08 00:00:00

abstract：:Ovarian cancer (OC) is the most lethal gynecological carcinoma due to the lack of diagnostic markers and effective drug targets. Discovery of new therapeutic targets in OC to improve the treatment outcome is urgently needed. We performed proteomic analysis of OC specimens and the paired normal tissues and revealed tha...

journal_title：Scientific reports

authors： Guo J,Li X,Zhang W,Chen Y,Zhu S,Chen L,Xu R,Lv Y,Wu D,Guo M,Liu X,Lu W,Deng H

更新日期：2019-09-02 00:00:00

abstract：:This study evaluated the prognostic value of a panel of 29 oncogenes derived from the analysis of The Cancer Genome Atlas (TCGA data) or from the recent literature on bladder tumors on a well-characterized series of muscle-invasive bladder cancer (MIBC) and non-MIBC (NMIBC) samples and tried to identify molecular prog...

journal_title：Scientific reports

authors： Le Goux C,Vacher S,Schnitzler A,Barry Delongchamps N,Zerbib M,Peyromaure M,Sibony M,Allory Y,Bieche I,Damotte D,Pignot G

更新日期：2020-10-06 00:00:00

abstract：:Because of its novel physical properties, two-dimensional materials have attracted great attention. From first-principle calculations and vibration frequencies analysis, we predict a new family of two-dimensional materials based on the idea of octet stability: honeycomb lattices of pnictogens (N, P, As, Sb, Bi). The b...

journal_title：Scientific reports

authors： Lee J,Tian WC,Wang WL,Yao DX

更新日期：2015-06-30 00:00:00

abstract：:Investigation of quantum spin Hall states in 1T' phase of the monolayer transition metal dichalcogenides has recently attracted the attention for its potential in nanoelectronic applications. While most of the theoretical findings in this regard deal with infinitely periodic crystal structures, here we employ density ...

journal_title：Scientific reports

authors： Das B,Sen D,Mahapatra S

更新日期：2020-04-21 00:00:00

abstract：:The Fabry-Pérot interferometer is used in a variety of high-precision optical interferometry applications, such as gravitational wave detection. It is also used in various types of laser resonators to act as a narrow band filter. In addition, ultra-compact Fabry-Pérot interferometers are used in the optical resonators...

journal_title：Scientific reports

authors： Tsujiie Y,Kawamura Y

更新日期：2018-10-12 00:00:00

abstract：:Prostaglandins (PGs) are hormone-like mediators in many physiological and pathological processes that are present in all vertebrates, in some terrestrial and aquatic invertebrates, and have also been identified in some macroalgae. They have recently been reported also in marine microalgae but their role as chemical me...

journal_title：Scientific reports

authors： Di Dato V,Barbarinaldi R,Amato A,Di Costanzo F,Fontanarosa C,Perna A,Amoresano A,Esposito F,Cutignano A,Ianora A,Romano G

更新日期：2020-03-25 00:00:00

abstract：:We present a highly ordered surface modification layer for polymers based on ambient solution-processed triptycene (Trip) derivatives for high-mobility organic thin-film transistors (OTFTs). The nested packing of Trip molecules results in the formation of 2D hexagonal arrays, which stack one-dimensionally on the surfa...

journal_title：Scientific reports

authors： Kondo M,Kajitani T,Uemura T,Noda Y,Ishiwari F,Shoji Y,Araki T,Yoshimoto S,Fukushima T,Sekitani T

更新日期：2019-06-24 00:00:00

abstract：:Dissecting the complex molecular interplay between the host plant and invading virus improves our understanding of the mechanisms underlying viral pathogenesis. In this study, immunoprecipitation together with the mass spectrometry analysis revealed that the heat shock protein 70 (Hsp70) family homolog, Hsc70-2, was c...

journal_title：Scientific reports

authors： Wang X,Cao X,Liu M,Zhang R,Zhang X,Gao Z,Zhao X,Xu K,Li D,Zhang Y

更新日期：2018-03-14 00:00:00