A Broadly Cross-protective Vaccine Presenting the Neighboring Epitopes within the VP1 GH Loop and VP2 EF Loop of Enterovirus 71.

abstract：:The Y chromosome has high genetic variability with low rates of parallel and back mutations, which make up the most informative haplotyping system. To examine whether Y chromosome haplogroups (Y-hgs) could modify the effects of autosomal variants on non-obstructive azoospermia (NOA), based on our previous genome-wide ...

journal_title：Scientific reports

authors： Lu C,Wen Y,Hu W,Lu F,Qin Y,Wang Y,Li S,Yang S,Lin Y,Wang C,Jin L,Shen H,Sha J,Wang X,Hu Z,Xia Y

更新日期：2016-09-15 00:00:00

abstract：:Brain-computer interfaces enable active communication and execution of a pre-defined set of commands, such as typing a letter or moving a cursor. However, they have thus far not been able to infer more complex intentions or adapt more complex output based on brain signals. Here, we present neuroadaptive generative mod...

journal_title：Scientific reports

authors： Kangassalo L,Spapé M,Ruotsalo T

更新日期：2020-09-07 00:00:00

abstract：:The effect of substitution of Nb by Mo in Nb40Ti30Ni30 was investigated with respect to microstructural features and hydrogen dissolution, diffusion and permeation. As-cast Nb40-xMoxTi30Ni30 (x = 0, 5, 10) alloys consist of primary bcc-Nb phase and binary eutectic (bcc-Nb + B2-TiNi). The substitution of Nb by Mo reduc...

journal_title：Scientific reports

authors： Li X,Liang X,Liu D,Chen R,Huang F,Wang R,Rettenmayr M,Su Y,Guo J,Fu H

更新日期：2017-03-16 00:00:00

abstract：:Escherichia coli lac repressor (LacI) is a paradigmatic transcriptional factor that controls the expression of lacZYA in the lac operon. This tetrameric protein specifically binds to the O1, O2 and O3 operators of the lac operon and forms a DNA loop to repress transcription from the adjacent lac promoter. In this arti...

journal_title：Scientific reports

authors： Fulcrand G,Dages S,Zhi X,Chapagain P,Gerstman BS,Dunlap D,Leng F

更新日期：2016-01-14 00:00:00

abstract：:DEMETER-like DNA glycosylases (DMLs) initiate the base excision repair-dependent DNA demethylation to regulate a wide range of biological processes in plants. Six putative SmDML genes, termed SmDML1-SmDML6, were identified from the genome of S. miltiorrhiza, an emerging model plant for Traditional Chinese Medicine (TC...

journal_title：Scientific reports

authors： Li J,Li C,Lu S

更新日期：2018-05-08 00:00:00

abstract：:The large and complex genome of Pseudomonas aeruginosa, which consists of significant portions (up to 20%) of transferable genetic elements contributes to the rapid development of antibiotic resistance. The whole genome sequences of 22 strains isolated from eye and cystic fibrosis patients in Australia and India betwe...

journal_title：Scientific reports

authors： Subedi D,Vijay AK,Kohli GS,Rice SA,Willcox M

更新日期：2018-10-23 00:00:00

abstract：:Efficient inactivation of Escherichia coli (E. coli) under visible (532 nm) pulsed light irradiation was achieved by fusion of a visible light-absorbing dye with E. coli. Inactivation experiments showed that 3-log inactivation of E. coli was obtained within 20 min under a 50 kJ/cm2 dose. This treatment time and dose m...

journal_title：Scientific reports

authors： Kohmura Y,Igami N,Tatsuno I,Hasegawa T,Matsumoto T

更新日期：2020-10-20 00:00:00

abstract：:Retinitis pigmentosa (RP) is one of hereditary retinal diseases characterized by the loss of photoreceptors. Cell transplantation has been clinically applied to treat RP patients. Human retinal progenitor cells (HRPCs) and human bone marrow-derived mesenchymal stem cells (HBMSCs) are the two commonly and practically u...

journal_title：Scientific reports

authors： Qu L,Gao L,Xu H,Duan P,Zeng Y,Liu Y,Yin ZQ

更新日期：2017-03-15 00:00:00

abstract：:Air-core magnetometers are amongst the most commonly used magnetic field detectors in biomedical instruments. They offer excellent sensitivity, low fabrication complexity and a robust, cost-effective solution. However, air-core magnetometers must be tailored to the specific application to achieve high sensitivity, whi...

journal_title：Scientific reports

authors： Pellicer-Guridi R,Vogel MW,Reutens DC,Vegh V

更新日期：2017-05-23 00:00:00

abstract：:Albacore tuna (Thunnus alalunga) is an important target of tuna fisheries in the Atlantic and Indian Oceans. The commercial catch of albacore is the highest globally among all temperate tuna species, contributing around 6% in weight to global tuna catches over the last decade. The accurate assessment and management of...

journal_title：Scientific reports

authors： Nikolic N,Montes I,Lalire M,Puech A,Bodin N,Arnaud-Haond S,Kerwath S,Corse E,Gaspar P,Hollanda S,Bourjea J,West W,Bonhommeau S

更新日期：2020-09-24 00:00:00

abstract：:Multiple Sclerosis (MS), is a chronic inflammatory autoimmune disorder of the central nervous system that leads to chronic demyelination with axonal damage and neuronal loss. Mesenchymal stem cells (MSCs) represent a promising therapeutic approach for MS. In the current study, we investigated the effects of MSCs deriv...

journal_title：Scientific reports

authors： Wang YL,Xue P,Xu CY,Wang Z,Liu XS,Hua LL,Bai HY,Zeng ZL,Duan HF,Li JF

更新日期：2018-01-29 00:00:00

abstract：:The transition from unicellular to multicellular organisms poses the question as to when genes that regulate cell-cell interactions emerged during evolution. The receptor and ligand pairing of plexins and semaphorins regulates cellular interactions in a wide range of developmental and physiological contexts. We survey...

journal_title：Scientific reports

authors： Junqueira Alves C,Yotoko K,Zou H,Friedel RH

更新日期：2019-02-13 00:00:00

abstract：:We investigated in this paper a novel bilayer composite obtained by sol-gel and spin coating of the ferroelectric 0.92Na0.5Bi0.5TiO3-0.08BaTiO3 (abbreviated as BNT-BT0.08) and ferromagnetic CoFe2O4 phases, for miniature low-frequency magnetic sensors and piezoelectric sensors. This heterostructure, deposited on Si-Pt ...

journal_title：Scientific reports

authors： Cernea M,Vasile BS,Surdu VA,Trusca R,Bartha C,Craciun F,Galassi C

更新日期：2018-12-14 00:00:00

abstract：:Sleep problems are considered a core symptom of depression. However, there is little information about the comorbidity of sleep problems and depression in low- and middle-income countries (LMICs), and whether sleep problems with depression confer additional risk for decrements in health compared to sleep problems alon...

journal_title：Scientific reports

authors： Stickley A,Leinsalu M,DeVylder JE,Inoue Y,Koyanagi A

更新日期：2019-08-19 00:00:00

abstract：:The ability to observe chemical reactions at the molecular level convincingly demonstrates the physical and chemical phenomena occurring throughout a reaction mechanism. Videos obtained through in situ transmission electron microscopy (TEM) revealed the oxidation of catalytic soot under practical reaction conditions. ...

journal_title：Scientific reports

authors： Kamatani K,Higuchi K,Yamamoto Y,Arai S,Tanaka N,Ogura M

更新日期：2015-07-08 00:00:00

abstract：:Myodural bridges have been described in various species as connective tissue structures "bridging" small cranio-cervical muscles to the dura. Myodural bridges are thought to stabilize the dural sac during head and neck movements and promote cerebrospinal fluid motion; however, their role in neurological diseases has n...

journal_title：Scientific reports

authors： McElroy A,Rashmir A,Manfredi J,Sledge D,Carr E,Stopa E,Klinge P

更新日期：2019-07-10 00:00:00

abstract：:We propose a quantum secure group communication protocol for the purpose of sharing the same message among multiple authorized users. Our protocol can remove the need for key management that is needed for the quantum network built on quantum key distribution. Comparing with the secure quantum network based on BB84, we...

journal_title：Scientific reports

authors： Li ZH,Zubairy MS,Al-Amri M

更新日期：2018-03-01 00:00:00

abstract：:A novel imaging-driven technique with an integrated fluorescence signature to enable automated enumeration of two species of cyanobacteria and an alga of somewhat similar morphology to one of the cyanobacteria is presented to demonstrate proof-of-concept that high accuracy, imaging-based, rapid water quality analysis ...

journal_title：Scientific reports

authors： Jin C,Mesquita MMF,Deglint JL,Emelko MB,Wong A

更新日期：2018-06-13 00:00:00

abstract：:Bacterial NhaB Na+/H+ exchangers belonging to the Ion Transporter superfamily are poorly characterized in contrast to Na+/H+ exchangers of the Cation Proton Antiporter superfamily which have NhaA from Escherichia coli as a prominent member. For a more detailed understanding of the intricacies of the exchanger's transp...

journal_title：Scientific reports

authors： Patiño-Ruiz M,Fendler K,Călinescu O

更新日期：2019-10-28 00:00:00

abstract：:Recognition of the potential for vegetated coastal ecosystems to store and sequester carbon has led to their increasing inclusion into global carbon budgets and carbon offset schemes. However, kelp forests have been overlooked in evaluations of this 'blue carbon', which have been limited to tidal marshes, mangrove for...

journal_title：Scientific reports

authors： Filbee-Dexter K,Wernberg T

更新日期：2020-07-23 00:00:00

abstract：:In cytochrome c oxidase (CytcO) reduction of O2 to water is linked to uptake of eight protons from the negative side of the membrane: four are substrate protons used to form water and four are pumped across the membrane. In bacterial oxidases, the substrate protons are taken up through the K and the D proton pathways,...

journal_title：Scientific reports

authors： Björck ML,Vilhjálmsdóttir J,Hartley AM,Meunier B,Näsvik Öjemyr L,Maréchal A,Brzezinski P

更新日期：2019-12-27 00:00:00

abstract：:Inconsistent findings have reported on the inflammatory potential of diet and cardiovascular disease (CVD) and mortality risk. The aim of this meta-analysis was to investigate the association between the inflammatory potential of diet as estimated by the dietary inflammatory index (DII) score and CVD or mortality risk...

journal_title：Scientific reports

authors： Zhong X,Guo L,Zhang L,Li Y,He R,Cheng G

更新日期：2017-07-25 00:00:00

abstract：:Little is known about the composition and clinical implications of lung microbiome in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia requiring invasive mechanical ventilation and intensive care unit admission. Therefore, this study aimed to explore the longitudinal changes ...

journal_title：Scientific reports

authors： Huang WC,Wu MF,Huang CC,Liu SY,Chen HC,Chen YY,Hsu JY,Huang CC

更新日期：2020-07-06 00:00:00

abstract：:Porous three-dimensional hydrogel scaffolds have an exquisite ability to promote tissue repair. However, because of their high water content and invasive nature during surgical implantation, hydrogels are at an increased risk of bacterial infection. Recently, we have developed elastic biomimetic cryogels, an advanced ...

journal_title：Scientific reports

authors： Joshi Navare K,Colombani T,Rezaeeyazdi M,Bassous N,Rana D,Webster T,Memic A,Bencherif SA

更新日期：2020-10-27 00:00:00

abstract：:Neutrophil elastase (NE) suppresses IL-8/CXCL8 in human airway smooth muscle cells (hASM) while stimulating its production in respiratory epithelial cells. This differential effect is mediated by the selective induction of NKRF and dysregulation in chronic inflammatory diseases. We hypothesized that the differential a...

journal_title：Scientific reports

authors： Ho SC,Wu SM,Feng PH,Liu WT,Chen KY,Chuang HC,Chan YF,Kuo LW,Lee KY

更新日期：2017-03-21 00:00:00

abstract：:Lipidised analgesic peptide prodrugs self-assemble into peptide nanofibers; with the nanofiber morphology protecting the peptide from plasma degradation and improving therapeutic efficacy. Extending this learning, we hypothesised that a self-assembling lipidized peptide arginine vasopressin (AVP) receptor agonist, tha...

journal_title：Scientific reports

authors： Patel S,Volpe AB,Awwad S,Schätzlein AG,Haider S,Liu B,Uchegbu IF

更新日期：2020-04-29 00:00:00

abstract：:El Niño-Southern Oscillation (ENSO), which is one of the main drivers of Earth's inter-annual climate variability, often causes a wide range of climate anomalies, and the advance prediction of ENSO is always an important and challenging scientific issue. Since a unified and complete ENSO theory has yet to be establish...

journal_title：Scientific reports

authors： Yan J,Mu L,Wang L,Ranjan R,Zomaya AY

更新日期：2020-05-15 00:00:00

abstract：:While TLR-activated pathways are key regulators of B cell responses in mammals, their impact on teleost B cells are scarcely addressed. Here, the potential of Atlantic salmon B cells to respond to TLR ligands was shown by demonstrating a constitutive expression of nucleic-acid sensing TLRs in magnetic sorted IgM+ cell...

journal_title：Scientific reports

authors： Jenberie S,Thim HL,Sunyer JO,Skjødt K,Jensen I,Jørgensen JB

更新日期：2018-02-23 00:00:00

abstract：:In this work the chalcopyrite CuIn3Se5-xTex (x = 0~0.5) with space group through isoelectronic substitution of Te for Se have been prepared, and the crystal structure dilation has been observed with increasing Te content. This substitution allows the anion position displacement ∆u = 0.25-u to be zero at x ≈ 0.15. Howe...

journal_title：Scientific reports

authors： Lu Y,Chen S,Wu W,Du Z,Chao Y,Cui J

更新日期：2017-01-06 00:00:00

abstract：:Non-functioning pituitary adenomas (NFPAs) are the most frequent pituitary tumors. The elucidation of the mechanisms of aggressive NFPAs in bone destruction is required in order to guide the clinical diagnosis and treatment of NFPAs. In the present study, we investigated the differential proteomics of fibroblasts isol...

journal_title：Scientific reports

authors： Zhang LY,Ge XL,Li Z,Tang YJ,Xiong YY,Li XJ,Liu JF,Wanggou SY,Li CT,Yang K,Chen X,Hu ZL,Liu YS,Liu ZX

更新日期：2017-12-13 00:00:00