Abstract:
:Sleep problems are considered a core symptom of depression. However, there is little information about the comorbidity of sleep problems and depression in low- and middle-income countries (LMICs), and whether sleep problems with depression confer additional risk for decrements in health compared to sleep problems alone. This study thus examined the association between sleep problems and depression and whether sleep problems with depression are associated with an increased risk for poorer health in 46 LMICs. Cross-sectional, community-based data from 237 023 adults aged ≥18 years from the World Health Survey (WHS) 2002-2004 were analyzed. Information on sleep problems (severe/extreme) and International Classification of Diseases 10th Revision depression/depression subtypes was collected. Multivariable logistic (binary and multinomial) and linear regression analyses were performed. Sleep problems were associated with subsyndromal depression (odds ratio [OR]: 2.23, 95% confidence interval [CI]: 1.84-2.70), brief depressive episode (OR = 2.48, 95% CI = 2.09-2.95) and depressive episode (OR = 3.61, 95% CI = 3.24-4.03). Sleep problems with depression (vs. sleep problems alone) conferred additional risk for anxiety, perceived stress and decrements in health in the domains of mobility, self-care, pain, cognition, and interpersonal activities. Clinicians should be aware that the co-occurrence of sleep problems and depression is associated with a variety of adverse health outcomes in LMICs. Detecting this co-occurrence may be important for treatment planning.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Stickley A,Leinsalu M,DeVylder JE,Inoue Y,Koyanagi Adoi
10.1038/s41598-019-48334-7subject
Has Abstractpub_date
2019-08-19 00:00:00pages
12011issue
1issn
2045-2322pii
10.1038/s41598-019-48334-7journal_volume
9pub_type
杂志文章abstract::Ascertaining the existence of hidden objects in a complex system, objects that cannot be observed from the external world, not only is curiosity-driven but also has significant practical applications. Generally, uncovering a hidden node in a complex network requires successful identification of its neighboring nodes, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03944
更新日期:2014-02-03 00:00:00
abstract::The pentameric serum IgMs are critical to immune defense and surveillance through cytotoxicity against microbes and nascent cancer cells. Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic cell clearance by ac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07824
更新日期:2015-01-16 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-37593-5
更新日期:2018-12-21 00:00:00
abstract::Low miR-96-5p expression is characteristic of many cancers but its role in breast cancer (BCa) remains poorly defined. Here, the role of miR-96-5p in BC development was assessed. We demonstrate that exogenously expressing miR-96-5p inhibits the proliferative, migratory and invasive capacity of BCa cells. Mechanistical...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56571-z
更新日期:2020-01-08 00:00:00
abstract::Targeting micrometer sized metal droplets with near-infrared sub-picosecond laser pulses generates intense stress-confined acoustic waves within the droplet. Spherical focusing amplifies their pressures. The rarefaction wave nucleates cavitation at the center of the droplet, which explosively expands with a repeatable...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-19140-w
更新日期:2018-01-12 00:00:00
abstract::In mosquitoes, precise and efficient finding of a host animal is crucial for survival. One of the poorly understood aspects of mosquito blood-feeding behavior is how these insects target an optimal site in order to penetrate the skin and blood vessels without alerting the host animal. Here we provide new findings that...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13444
更新日期:2015-08-26 00:00:00
abstract::Remote photoplethysmography (PPG) is an optical measurement technique with established applications in vital signs monitoring. Recently, the consensual understanding of blood volume variations (BVVs) as the origin of PPG signals was challenged, raising validity concerns about the remote SpO2 methodology. Recognizing t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26068-2
更新日期:2018-05-31 00:00:00
abstract::The construction of three-dimensional graphene aerogels (GAs) is of great importance owing to their outstanding properties for various applications. Up to now, the combination of ultralow weight and super mechanical strength for GA remains a great challenge. Here we demonstrate the fabrication of cellular GAs by a fac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25830
更新日期:2016-05-12 00:00:00
abstract::DNA is organized and compacted into higher-order structures in order to fit within nuclei and to facilitate gene regulation. Mechanisms by which higher order chromatin structures are established and maintained are poorly understood. In C. elegans, nuclear-localized small RNAs engage the nuclear RNAi machinery to regul...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45052-y
更新日期:2019-06-21 00:00:00
abstract::Identifying early life-stage transitions limiting seagrass recruitment could improve our ability to target demographic processes most responsive to management. Here we determine the magnitude of life-stage transitions along gradients in physical disturbance limiting seedling establishment for the marine angiosperm, Po...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13833-y
更新日期:2017-11-01 00:00:00
abstract::In the dominant livestock systems of Sahelian countries herds have to move across territories. Their mobility is often a source of conflict with farmers in the areas crossed, and helps spread diseases such as Rift Valley Fever. Knowledge of the routes followed by herds is therefore core to guiding the implementation o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65132-8
更新日期:2020-05-20 00:00:00
abstract::Sensory representations are typically endowed with intrinsic noise, leading to variability and inaccuracies in perceptual responses. The Bayesian framework accounts for an optimal strategy to deal with sensory-motor uncertainty, by combining the noisy sensory input with prior information regarding the distribution of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34512-6
更新日期:2018-11-06 00:00:00
abstract::We present a new model of ESR1 network regulation based on analysis of Doxorubicin, Estradiol, and TNFα combination treatment in MCF-7. We used Doxorubicin as a therapeutic agent, TNFα as marker and mediator of an inflammatory microenvironment and 17β-Estradiol (E2) as an agonist of Estrogen Receptors, known predispos...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51349-9
更新日期:2019-10-23 00:00:00
abstract::Nanocarrier systems for the encapsulation of agrochemicals can contribute to sustainable agriculture, but few nanosystems have been developed for plant growth regulators (PGRs). The present study evaluated the effects of seed priming using alginate/chitosan (nanoALG/CS) and chitosan/tripolyphosphate (nanoCS/TPP) conta...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43494-y
更新日期:2019-05-09 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-73944-x
更新日期:2020-10-09 00:00:00
abstract::TP53 mutation (i.e., loss of normal-p53) may evoke epithelial-mesenchymal transition (EMT), which was previously attributed to loss of certain miRNAs. However, not all epithelial cells undergo EMT upon TP53 mutation, and the p53-miRNA axis may not fully explain p53 function in epithelial integrity. We here show two mo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20043-7
更新日期:2018-01-25 00:00:00
abstract::Fluorine-19 (19F) magnetic resonance imaging (MRI) of injected perfluorocarbons (PFCs) can be used for the quantification and monitoring of inflammation in diseases such as atherosclerosis. To advance the translation of this technique to the clinical setting, we aimed to 1) demonstrate the feasibility of quantitative ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53905-9
更新日期:2019-11-25 00:00:00
abstract::Multiple infections of avian influenza viruses (AIVs) in poultry or wild birds contribute to the continued evolution of H5 subtype viruses in nature and provide potential recombination of AIVs of different origins. In this study, we carried out surveillance of AIVs in ducks, geese and the environment of a community in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25549
更新日期:2016-05-06 00:00:00
abstract::The phylogenetic characteristics of microbial communities associated with periodontitis have been well studied, however, little is known about the functional endowments of this ecosystem. The present study examined 73 microbial assemblages from 25 individuals with generalized chronic periodontitis and 25 periodontally...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38993
更新日期:2016-12-19 00:00:00
abstract::Melanoma patients' plasma contains exosomes produced by malignant and normal cells. Plasma exosomes were isolated and separated by immunocapture into two fractions: melanoma cell-derived exosomes (MTEX) and normal cell-derived exosomes (non-MTEX). Immunosuppressive effects of MTEX on primary human immune cells were ev...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56542-4
更新日期:2020-01-09 00:00:00
abstract::Retinitis pigmentosa (RP) is one of hereditary retinal diseases characterized by the loss of photoreceptors. Cell transplantation has been clinically applied to treat RP patients. Human retinal progenitor cells (HRPCs) and human bone marrow-derived mesenchymal stem cells (HBMSCs) are the two commonly and practically u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00241-5
更新日期:2017-03-15 00:00:00
abstract::Rhythms of life are dictated by oscillations, which take place in a wide rage of biological scales. In bacteria, for example, oscillations have been proven to control many fundamental processes, ranging from gene expression to cell divisions. In genetic circuits, oscillations originate from elemental block such as aut...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07088
更新日期:2014-11-18 00:00:00
abstract::Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies. The genomic landscape of the PDAC genome features four frequently mutated genes (KRAS, CDKN2A, TP53, and SMAD4) and dozens of candidate driver genes altered at low frequency, including potential clinical targets. Circulating cell-free...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep18425
更新日期:2015-12-16 00:00:00
abstract::The recently evolved field of synthetic biology has revolutionized the way we think of biology as an "engineerable" discipline. The newly sprouted branch is constantly in need of simple, cost-effective and automatable DNA-assembly methods. We have developed a reliable DNA-assembly system, ZeBRα (Zero-Background Redα),...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39768-0
更新日期:2019-02-27 00:00:00
abstract::Rejuvenation is the configurational excitation of amorphous materials and is one of the more promising approaches for improving the deformability of amorphous metals that usually exhibit macroscopic brittle fracture modes. Here, we propose a method to control the level of rejuvenation through systematic thermal proces...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10545
更新日期:2015-05-26 00:00:00
abstract::The capacity of graphene oxide nanoparticles (nGOx) to reduce or increase As and metals availability in polluted soils was compared with that of zero valent iron nanoparticles (nZVI). The nanomaterials used in this study were characterized by X-ray techniques, CHNS-O analysis, dynamic light scattering, and microscopy ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58852-4
更新日期:2020-02-05 00:00:00
abstract::Colon cancer stem cells have been attributed to poor prognosis, therapeutic resistance and aggressive nature of the malignancy. Recent reports associated CD44v6 expression with relapse, metastasis and reduced 5-year survival of colon cancer patients, thereby making it a potential therapeutic target. Thus, in this stud...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-35069-0
更新日期:2018-11-19 00:00:00
abstract::Polarization sensitive and insensitive color filters have important applications in the area of nano-spectroscopy and CCD imaging applications. Metallic nanostructures provide an efficient way to design and engineer ultrathin color filters. These nanostructures have capability to split the white light into fundamental...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07986-z
更新日期:2017-08-14 00:00:00
abstract::An impairment of cardiac function is a key feature of the cardiovascular failure associated with sepsis. Although there is some evidence that suppression of sarcoplasmic reticulum Ca2+-ATP-ase (SERCA2) contributes to septic cardiomyopathy, it is not known whether prevention of the down-regulation of SERCA2 improves ou...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37277
更新日期:2016-11-17 00:00:00
abstract::Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in extracellular matri...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15561
更新日期:2015-10-23 00:00:00