Abstract:
:The objective of this study was to assess the evolution of diffusion-weighted imaging (DWI) and diffusion-tensor imaging (DTI) over the first month of life in asphyxiated newborns treated with hypothermia and to compare it with that of healthy newborns. Asphyxiated newborns treated with hypothermia were enrolled prospectively; and the presence and extent of brain injury were scored on each MRI. Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values were measured in the basal ganglia, in the white matter and in the cortical grey matter. Sixty-one asphyxiated newborns treated with hypothermia had a total of 126 ADC and FA maps. Asphyxiated newborns developing brain injury eventually had significantly decreased ADC values on days 2-3 of life and decreased FA values around day 10 and 1 month of life compared with those not developing brain injury. Despite hypothermia treatment, asphyxiated newborns may develop brain injury that still can be detected with advanced neuroimaging techniques such as DWI and DTI as early as days 2-3 of life. A study of ADC and FA values over time may aid in the understanding of how brain injury develops in these newborns despite hypothermia treatment.
journal_name
Neural Plastjournal_title
Neural plasticityauthors
Kwan S,Boudes E,Benseler A,Gilbert G,Saint-Martin C,Shevell M,Wintermark Pdoi
10.1155/2015/653727subject
Has Abstractpub_date
2015-01-01 00:00:00pages
653727eissn
2090-5904issn
1687-5443journal_volume
2015pub_type
杂志文章abstract::With action video games (AVGs) becoming increasingly popular worldwide, the cognitive benefits of AVG experience have attracted continuous research attention over the past two decades. Research has repeatedly shown that AVG experience can causally enhance cognitive ability and is related to neural plasticity in gray m...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2017/7543686
更新日期:2017-01-01 00:00:00
abstract::Transcranial Direct Current Stimulation (tDCS) is an emerging tool to improve upper limb motor functions after stroke acquired in adulthood; however, there is a paucity of reports on its efficacy for upper limb motor rehabilitation in congenital or early-acquired stroke. In this pilot study we have explored, for the f...
journal_title:Neural plasticity
pub_type: 杂志文章,随机对照试验
doi:10.1155/2019/2184398
更新日期:2019-01-15 00:00:00
abstract:Background:Phosphene generation is an objective physical measure of potential transcranial alternating current stimulation (tACS) biological side effects. Interpretations from phosphene analysis can serve as a first step in understanding underlying mechanisms of tACS in healthy human subjects and assist validation of c...
journal_title:Neural plasticity
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doi:10.1155/2018/8525706
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journal_title:Neural plasticity
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2018/7301530
更新日期:2018-12-02 00:00:00
abstract::Hyperpolarization-activated, cyclic nucleotide-gated nonselective (HCN) channels modulate both membrane potential and resistance and play a significant role in synaptic plasticity. We compared the influence of HCN channels on long-term depression (LTD) at the medial perforant path-granule cell synapse in early postnat...
journal_title:Neural plasticity
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2018/8105480
更新日期:2018-03-26 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2013/318521
更新日期:2013-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2020/8884318
更新日期:2020-12-08 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2018/2546250
更新日期:2018-05-20 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2016/9890827
更新日期:2016-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2016/7453149
更新日期:2016-01-01 00:00:00
abstract::Two principal component analyses of anxiety were undertaken investigating two strains of mice (ABP/Le and C57BL/6ByJ) in two different experiments, both classical tests for assessing anxiety in rodents. The elevated plus-maze and staircase were used for the first experiment, and a free exploratory paradigm and light-d...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2007/35457
更新日期:2007-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2012/378307
更新日期:2012-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2009/294192
更新日期:2009-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2013/698528
更新日期:2013-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2019/3152129
更新日期:2019-01-21 00:00:00
abstract::Transcranial direct current stimulation (tDCS) can enhance the effect of conventional therapies in post-stroke neurorehabilitation. The ability to predict an individual's potential for tDCS-induced recovery may permit rehabilitation providers to make rational decisions about who will be a good candidate for tDCS thera...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2020/8859394
更新日期:2020-11-25 00:00:00
abstract::The entorhinal cortex (EC) is a nodal and independent mnemonic element of the medial temporal lobe memory circuit as it forms a bidirectional interface between the neocortex and hippocampus. Within the EC, intra- and inter-lamellar associational connections occur via horizontal and columnar projections, respectively. ...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2008/814815
更新日期:2008-01-01 00:00:00
abstract::Mastoparan-7 (Mas-7), an analogue of the peptide mastoparan, which is derived from wasp venom, is a direct activator of Pertussis toxin- (PTX-) sensitive G proteins. Mas-7 produces several biological effects in different cell types; however, little is known about how Mas-7 influences mature hippocampal neurons. We exa...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2016/4258171
更新日期:2016-01-01 00:00:00
abstract::We do not all grow older in the same way. Some individuals have a cognitive decline earlier and faster than others who are older in years but cerebrally younger. This is particularly easy to verify in people who have maintained regular physical activity and healthy and cognitively stimulating lifestyle and even in the...
journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2017/7219461
更新日期:2017-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2015/503079
更新日期:2015-01-01 00:00:00
abstract::In this study, we attempted to test whether tyrosine hydroxylase (TH), the first rate-limiting enzyme of catecholamine synthesis, is confined to the perikarya of activated magnocellular vasopressinergic (VPergic) neurons or is also present in their distal axons in the pituitary posterior lobe (PL). In addition, we eva...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/NP.2000.179
更新日期:2000-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2009/612698
更新日期:2009-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2017/3026749
更新日期:2017-01-01 00:00:00
abstract::Freezing of gait (FoG) is among the most disabling symptoms of Parkinson's disease (PD) patients. Recent studies showed that action observation training (AOT) with repetitive practice of the observed actions represents a strategy to induce longer-lasting effects compared with standard physiotherapy. We investigated wh...
journal_title:Neural plasticity
pub_type: 杂志文章,随机对照试验
doi:10.1155/2018/4897276
更新日期:2018-05-27 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2016/3462309
更新日期:2016-01-01 00:00:00
abstract::The role of the right hemisphere (RH) in recovery from aphasia is incompletely understood. The present study quantified RH grey matter (GM) volume in individuals with chronic stroke-induced aphasia and cognitively healthy people using voxel-based morphometry. We compared group differences in GM volume in the entire RH...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2017/5601509
更新日期:2017-01-01 00:00:00
abstract::The concept of a topographical map of the corpus callosum (CC) has emerged from human lesion studies and from electrophysiological and anatomical tracing investigations in other mammals. Over the last few years a rising number of researchers have been reporting functional magnetic resonance imaging (fMRI) activation i...
journal_title:Neural plasticity
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doi:10.1155/2013/251308
更新日期:2013-01-01 00:00:00
abstract::To decipher the genotype-phenotype correlation of auditory neuropathy (AN) caused by AIFM1 variations, as well as the phenotype progression of these patients, exploring the potential molecular pathogenic mechanism of AN. A total of 36 families of individuals with AN (50 cases) with AIFM1 variations were recruited and ...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2020/5625768
更新日期:2020-07-01 00:00:00