Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice.

abstract：:Fragile X syndrome (FXS) is an inheritable neuropsychological disease caused by expansion of the CGG trinucleotide repeat affecting the fmr1 gene on X chromosome, resulting in silence of the fmr1 gene and failed expression of FMRP. Patients with FXS suffer from cognitive impairment, sensory integration deficits, learn...

journal_title：Neural plasticity

authors： Yang T,Zhao H,Lu C,Li X,Xie Y,Fu H,Xu H

更新日期：2016-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a worldwide endemic that results in unacceptably high morbidity and mortality. Secondary injury processes following primary injury are composed of intricate interactions between assorted molecules that ultimately dictate the degree of longer-term neurological deficits. One comparatively...

journal_title：Neural plasticity

authors： Budinich CS,Chen H,Lowe D,Rosenberger JG,Bernstock JD,McCabe JT

更新日期：2012-01-01 00:00:00

abstract：:The entorhinal cortex (EC) is a nodal and independent mnemonic element of the medial temporal lobe memory circuit as it forms a bidirectional interface between the neocortex and hippocampus. Within the EC, intra- and inter-lamellar associational connections occur via horizontal and columnar projections, respectively. ...

journal_title：Neural plasticity

authors： Ma L,Alonso A,Dickson CT

更新日期：2008-01-01 00:00:00

abstract：:Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson's disease (PD). In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onset of motor symptoms...

journal_title：Neural plasticity

authors： Longhena F,Faustini G,Missale C,Pizzi M,Spano P,Bellucci A

更新日期：2017-01-01 00:00:00

abstract：:Brain cancer is a common type of childhood malignancy, and radiotherapy (RT) is a mainstay of treatment. RT is effective for tumor eradication, and survival rates are high. However, RT damages the brain and disrupts ongoing developmental processes, resulting in debilitating cognitive "late" effects that may take years...

journal_title：Neural plasticity

authors： Rodgers SP,Trevino M,Zawaski JA,Gaber MW,Leasure JL

更新日期：2013-01-01 00:00:00

abstract：:Functional and morphological studies in children affected by Attention Deficit Hyperactivity Disorder (ADHD) suggest a prefrontal cortex (PFc) dysfunction. This cortical region is regulated by subcortical systems including noradrenergic (NEergic), dopaminergic (DAergic), cholinergic, serotonergic, and histaminergic pa...

journal_title：Neural plasticity

authors： Viggiano D,Ruocco LA,Arcieri S,Sadile AG

更新日期：2004-01-01 00:00:00

abstract：:Dishabituation is a return of a habituated response if context or contingency changes. In the mammalian olfactory system, metabotropic glutamate receptor mediated synaptic depression of cortical afferents underlies short-term habituation to odors. It was hypothesized that a known antagonistic interaction between these...

journal_title：Neural plasticity

authors： Smith JJ,Shionoya K,Sullivan RM,Wilson DA

更新日期：2009-01-01 00:00:00

abstract：:Histamine H4 receptor has been confirmed to play a role in evoking peripheral pruritus. However, the ionic and intracellular signaling mechanism of activation of H4 receptor on the dorsal root ganglion (DRG) neurons is still unknown. By using cell culture and calcium imaging, we studied the underlying mechanism of act...

journal_title：Neural plasticity

authors： Jian T,Yang N,Yang Y,Zhu C,Yuan X,Yu G,Wang C,Wang Z,Shi H,Tang M,He Q,Lan L,Wu G,Tang Z

更新日期：2016-01-01 00:00:00

abstract：:Motoneurons develop extensive dendritic trees for receiving excitatory and inhibitory synaptic inputs to perform a variety of complex motor tasks. At birth, the somatodendritic domains of mouse hypoglossal and lumbar motoneurons have dense filopodia and spines. Consistent with Vaughn's synaptotropic hypothesis, we pro...

journal_title：Neural plasticity

authors： Kanjhan R,Noakes PG,Bellingham MC

更新日期：2016-01-01 00:00:00

abstract：:Anxiety is most common among Alzheimer's disease (AD) patients with an age at onset under age 65. Apolipoprotein E4 (apoE4) is a risk factor for developing AD at an earlier age and might contribute to this effect. In mice, apoE plays a role in the regulation of anxiety, which might involve histamine receptor-mediated ...

journal_title：Neural plasticity

authors： Raber J

更新日期：2007-01-01 00:00:00

abstract：:Although many studies have investigated the functions of histidine triad nucleotide-binding protein 1 (HINT1), its roles in neurobiological processes remain to be fully elucidated. As a member of the histidine triad (HIT) enzyme superfamily, HINT1 is distributed in almost every organ and has both enzymatic and nonenzy...

journal_title：Neural plasticity

authors： Liu P,Liu Z,Wang J,Ma X,Dang Y

更新日期：2017-01-01 00:00:00

abstract：:The habituation/cross-habituation test (HaXha) is a spontaneous odor discrimination task that has been used for many decades to evaluate olfactory function in animals. Animals are presented repeatedly with the same odorant after which a new odorant is introduced. The time the animal explores the odor object is measure...

journal_title：Neural plasticity

authors： Coronas-Samano G,Ivanova AV,Verhagen JV

更新日期：2016-01-01 00:00:00

abstract：:Chronic shoulder pain (CSP) is the third most common musculoskeletal problem. For maximum treatment effectiveness, most acupuncturists usually choose acupoint in the nonpainful side, to alleviate pain or improve shoulder function. This method is named opposite needling, which means acupuncture points on the right side...

journal_title：Neural plasticity

authors： Yan CQ,Huo JW,Wang X,Zhou P,Zhang YN,Li JL,Kim M,Shao JK,Hu SQ,Wang LQ,Liu CZ

更新日期：2020-04-25 00:00:00

abstract：:Ionizing radiation is omnipresent. We are continuously exposed to natural (e.g., radon and cosmic) and man-made radiation sources, including those from industry but especially from the medical sector. The increasing use of medical radiation modalities, in particular those employing low-dose radiation such as CT scans,...

journal_title：Neural plasticity

authors： Verreet T,Verslegers M,Quintens R,Baatout S,Benotmane MA

更新日期：2016-01-01 00:00:00

abstract：:We analyzed operant discrimination in detelencephalated pigeons and neuroanatomical substrates after long-term detelencephalation. In Experiment I, experimental pigeons with massive telencephalic ablation and control pigeons were conditioned to key peck for food. Successive discrimination was made under alternating re...

journal_title：Neural plasticity

authors： Cerutti SM,Diaz-Cintra S,Cintra L,Ferrari EA

更新日期：2003-01-01 00:00:00

abstract：:Perceptual learning can be specific to a trained stimulus or optimally generalized to novel stimuli with the breadth of generalization being imperative for how we structure perceptual training programs. Adapting an established auditory interval discrimination paradigm to utilise complex signals, we trained human adult...

journal_title：Neural plasticity

authors： Brown DJ,Proulx MJ

更新日期：2013-01-01 00:00:00

abstract：Objective:To determine whether and how longitudinal acupuncture modulates the impaired default mode network (DMN) in chronic migraine (CM) patients without aura. Methods:Resting-state functional magnetic resonance imaging (fMRI) data from 14 CM patients treated with longitudinal pre- and postacupuncture treatment (PPA...

journal_title：Neural plasticity

authors： Zou Y,Tang W,Li X,Xu M,Li J

更新日期：2019-03-18 00:00:00

abstract：:Mirror visual feedback (MVF) therapy has been applied to improve upper limb function in stroke. When combined with motor training, MVF improves the performance of the trained and untrained hand by enhancing the excitability of both primary motor cortices (M1s). Bradykinesia is a typical feature of Parkinson's disease ...

journal_title：Neural plasticity

authors： Bonassi G,Pelosin E,Ogliastro C,Cerulli C,Abbruzzese G,Avanzino L

更新日期：2016-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in elderly people. It is an irreversible and progressive brain disease. In this paper, we utilized diffusion-weighted imaging (DWI) to detect abnormal topological organization of white matter (WM) structural networks. We compared the differences between WM c...

journal_title：Neural plasticity

authors： Wang T,Shi F,Jin Y,Yap PT,Wee CY,Zhang J,Yang C,Li X,Xiao S,Shen D

更新日期：2016-01-01 00:00:00

abstract：:Evidence from neuropathological, genetic, animal model, and biochemical studies has indicated that the accumulation of amyloid-beta (Aβ) is associated with, and probably induces, profound neuronal changes in brain regions critical for memory and cognition in the development of Alzheimer's disease (AD). There is consid...

journal_title：Neural plasticity

authors： Guntupalli S,Widagdo J,Anggono V

更新日期：2016-01-01 00:00:00

abstract：:Autosomal dominant nonsyndromic hearing loss (ADNSHL) is extremely heterogeneous. So far the genetic etiological contribution of the gene POU4F3 associated with ADNSHL has been rarely reported. In our previous study, a c.603_604delGG mutation in the hair cell specific gene POU4F3 has been identified as the pathogenic ...

journal_title：Neural plasticity

authors： He L,Pang X,Chen P,Wu H,Yang T

更新日期：2016-01-01 00:00:00

abstract：Background:Surround inhibition is a system that sharpens sensation by creating an inhibitory zone around the central core of activation. In the motor system, this mechanism probably contributes to the selection of voluntary movements, and it seems to be lost in dystonia. Objectives. To explore if sensory information is...

journal_title：Neural plasticity

authors： Terranova C,Rizzo V,Morgante F,Maggio R,Calamuneri A,Chillemi G,Girlanda P,Quartarone A

更新日期：2018-10-10 00:00:00

abstract：:Rapidly emerging evidence implicates perineuronal nets (PNNs) and extracellular matrix (ECM) molecules that compose or interact with PNNs, in the pathophysiology of several psychiatric disorders. Studies on schizophrenia, autism spectrum disorders, mood disorders, Alzheimer's disease, and epilepsy point to the involve...

journal_title：Neural plasticity

authors： Pantazopoulos H,Berretta S

更新日期：2016-01-01 00:00:00

abstract：:The concept of a topographical map of the corpus callosum (CC) has emerged from human lesion studies and from electrophysiological and anatomical tracing investigations in other mammals. Over the last few years a rising number of researchers have been reporting functional magnetic resonance imaging (fMRI) activation i...

journal_title：Neural plasticity

authors： Fabri M,Polonara G

更新日期：2013-01-01 00:00:00

abstract：:Two principal component analyses of anxiety were undertaken investigating two strains of mice (ABP/Le and C57BL/6ByJ) in two different experiments, both classical tests for assessing anxiety in rodents. The elevated plus-maze and staircase were used for the first experiment, and a free exploratory paradigm and light-d...

journal_title：Neural plasticity

authors： Clément Y,Joubert C,Kopp C,Lepicard EM,Venault P,Misslin R,Cadot M,Chapouthier G

更新日期：2007-01-01 00:00:00

abstract：:The present study investigates whether a combined cognitive and physical training may induce changes in the cortical activity as measured via electroencephalogram (EEG) and whether this change may index a deceleration of pathological processes of brain aging. Seventy seniors meeting the clinical criteria of mild cogni...

journal_title：Neural plasticity

authors： Styliadis C,Kartsidis P,Paraskevopoulos E,Ioannides AA,Bamidis PD

更新日期：2015-01-01 00:00:00

abstract：:Hearing impairment is one of the most common sensory disease, of which more than 50% is attributed to a genetic etiology. The goal of this research is to explore the genetic cause of a Chinese deafness pedigree who was excluded of GJB2, SLC26A4, or MtDNA12SrRNA variants. Three variants, c.3971C>A (p.A1324D), c.4011ins...

journal_title：Neural plasticity

authors： Zhang F,Xu L,Xiao Y,Li J,Bai X,Wang H

更新日期：2018-04-05 00:00:00

abstract：:Objective. To explore cortical reorganization of patients recovered from Bell's palsy (BP) by task-state functional magnetic resonance imaging (fMRI) during finger and orofacial movements and provide more evidence for acupuncture clinical treatment of BP. Methods. We collected 17 BP patients with complete clinical rec...

journal_title：Neural plasticity

authors： Lee J,Yang J,Li C,Yuan A,Wu H,Wang A,Xue Q,Wang T,Wang L,Gao T

更新日期：2016-01-01 00:00:00

abstract：Background:Parkinson's disease (PD) patients experience cognitive impairment which has been related to reduced quality of life and functional disability. These symptoms usually progress until dementia occurs. Some studies have been published assessing the efficacy of cognitive treatments on improving cognition, functio...

journal_title：Neural plasticity

authors： Díez-Cirarda M,Ibarretxe-Bilbao N,Peña J,Ojeda N

更新日期：2018-05-06 00:00:00

abstract：:Ceramides induce important intracellular signaling pathways, modulating proliferation, migration, apoptosis, and inflammation. However, the relevance of the ceramide metabolism in the reconvalescence phase after stroke is unclear. Besides its well-known property as a selective serotonin reuptake inhibitor, fluoxetine ...

journal_title：Neural plasticity

authors： Brunkhorst R,Friedlaender F,Ferreirós N,Schwalm S,Koch A,Grammatikos G,Toennes S,Foerch C,Pfeilschifter J,Pfeilschifter W

更新日期：2015-01-01 00:00:00