Mirror Visual Feedback to Improve Bradykinesia in Parkinson's Disease.

Abstract:

:Mirror visual feedback (MVF) therapy has been applied to improve upper limb function in stroke. When combined with motor training, MVF improves the performance of the trained and untrained hand by enhancing the excitability of both primary motor cortices (M1s). Bradykinesia is a typical feature of Parkinson's disease (PD), characterized by slowness in the execution of movement. This condition is often asymmetrical and possibly supported by a volitional hypoactivation of M1. MVF therapy could tentatively treat bradykinesia since the untrained hand, which benefits from the exercise, is generally more severely impaired in undertaking sequential movements. Aim of the study was to evaluate whether MVF therapy may improve bradykinesia of the more affected hand in PD patients. Twelve PD patients and twelve healthy controls performed for 10 minutes a finger sequence, receiving MVF of the more affected/nondominant hand. Before and after MVF training, participants performed a finger sequence at their spontaneous pace with both hands. M1 excitability was assessed in the trained and untrained hemispheres by means of transcranial magnetic stimulation. Movement speed increased after MVF training in either hand of both groups. MVF therapy enhanced cortical excitability of M1s in both groups. Our preliminary data support the use of MVF therapy to improve bradykinesia in PD patients.

journal_name

Neural Plast

journal_title

Neural plasticity

authors

Bonassi G,Pelosin E,Ogliastro C,Cerulli C,Abbruzzese G,Avanzino L

doi

10.1155/2016/8764238

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

8764238

eissn

2090-5904

issn

1687-5443

journal_volume

2016

pub_type

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