Abstract:
:Exposure following pelvic organ prolapse repair has been observationally associated with wrinkling of the implanted mesh. The purpose of this study was to quantify the impact of variable boundary conditions on the out-of-plane deformations of mesh subjected to tensile loading. Using photogrammetry and surface curvature analyses, deformed geometries were accessed for two commercially available products. Relative to standard clamping methods, the amount of out-of-plane deformation significantly increased when point loads were introduced to simulate suture fixation in-vivo. These data support the hypothesis that regional increases in the concentration of mesh potentially enhance the host׳s foreign body response, leading to exposure.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Barone WR,Amini R,Maiti S,Moalli PA,Abramowitch SDdoi
10.1016/j.jbiomech.2015.02.061subject
Has Abstractpub_date
2015-06-25 00:00:00pages
1566-74issue
9eissn
0021-9290issn
1873-2380pii
S0021-9290(15)00153-0journal_volume
48pub_type
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journal_title:Journal of biomechanics
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abstract::Head injuries frequently occur in American football and other contact sports. Uncertainty on the effects of cervical muscle properties on head injury risk may be due to the limitations of previous observational studies. This simulation study employs a musculoskeletal model of the head and neck to investigate the effec...
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