Abstract：
:Porcine bioprosthesis were treated with 0.625% glutaraldehyde and stabilized under changing pressure from 4 to 30 mmHg. Bovine pericardium and 12 biovalves (of age between 14 days and 80 months) after implantation in the human body were investigated (7 porcine PB and 5 pericardial bioprosthesis--PCB). Circumferential and radial strips from porcine aortic valve leaflets, bovine pericardium and bioprosthetic leaflets were studied in light, transmitting and scanning electron microscopy. Uniaxial load tests were carried out to examine the deformability and strength of these tissues. Microscopic examination of the biovalves revealed that the PB and PCB tissue retained its original architecture, but with alterations in detailed structure. The collagen bundles stuck together with vacuolization between them. There were some areas of the collagen structure fragmentation which could lead to complete necrosis. Eighty months after implantation in patients, the PCB became more extensible and its ultimate strain increases 2.5 times. Ultimate stress decreases in the radial direction from 9.43 to 2.88 MPa, and in the circumferential direction from 9.43 to 6.44 MPa. Forty-eight months after implantation, PB tissue's ultimate stress decreases in the circumferential direction from 4.06 to 1.99 MPa. At the same time ultimate strain increases from 13 to 22%. This study is to improve the methods of tissue stabilization in 0.625% glutaraldehyde solution for the first 48 h at cyclic, changing construction of biovalves soft supporting stent after 48 h.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Purinya B,Kasyanov V,Volkolakov J,Latsis R,Tetere Gdoi
10.1016/0021-9290(94)90027-2subject
Has Abstractpub_date
1994-01-01 00:00:00pages
1-11issue
1eissn
0021-9290issn
1873-2380pii
0021-9290(94)90027-2journal_volume
27pub_type
杂志文章abstract：:A computer-controlled mechanical culture system was designed to investigate the interaction between mechanical stimuli and the metabolism of articular cartilage. The main features of this system include the following capabilities: (1) Accurately controlled static, permanent cyclic or intermittent cyclic mechanical loa...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(97)00040-7
更新日期：1997-08-01 00:00:00
abstract：:The literature contains many measurements of the fatigue properties of compact bone, but these experimental results have been difficult to interpret and use due to a large amount of apparent scatter: variation in the number of cycles to failure for a given cyclic stress or strain range. Recently Taylor (1998a, Journal...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00112-8
更新日期：1999-11-01 00:00:00
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journal_title：Journal of biomechanics
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更新日期：2014-12-18 00:00:00
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pub_type： 临床试验,杂志文章,多中心研究
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更新日期：2012-09-21 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109791
更新日期：2020-05-22 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(82)90082-3
更新日期：1982-01-01 00:00:00
abstract：:Anesthetized, carefully positioned, female, weanling, white-haired pigs were used to test the hypothesis that (1) interface pressure, the pressure between the skin and an external load, can be used to predict the interstitial fluid pressure over the wings of ilia and the last dorsal spinous process and (2) three-dimen...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(91)90322-e
更新日期：1991-01-01 00:00:00
abstract：:The active control of the trunk plays an important role in frontal plane gait stability. We characterized trunk control in response to different step widths using a novel feedback system and examined the different effects of wide and narrow step widths as they each present unique task demands. Twenty healthy young adu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.110135
更新日期：2021-01-04 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.09.004
更新日期：2014-11-28 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(91)90007-a
更新日期：1991-01-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(90)90051-4
更新日期：1990-01-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2005.01.004
更新日期：2006-01-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.09.003
更新日期：2016-04-11 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(01)00056-2
更新日期：2001-08-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.10.020
更新日期：2019-01-03 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(88)90127-3
更新日期：1988-01-01 00:00:00
abstract：:The breaking of left-right symmetry in the mammalian embryo is believed to occur in a transient embryonic structure, the node, when cilia create a leftward flow of liquid. The two-cilia hypothesis proposes that the node contains two kinds of primary cilia: motile cilia that rotate autonomously to generate the leftward...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.10.040
更新日期：2009-02-09 00:00:00
abstract：:Radioembolization, which consist of the implantation of radioactive microspheres via intra-arterially placed microcatheter, is a safe and effective treatment for liver cancer. Nevertheless, radioembolization-related complications and side effects may arise, which are an active area of ongoing research. The catheter de...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.09.035
更新日期：2016-11-07 00:00:00
abstract：:The question of whether the mechanical stiffness of a coronary bypass or that of a diseased coronary artery can have a significant effect on the hemodynamics in these vessels is addressed analytically, with emphasis on the effects of wave reflections. The analysis is based on a model of the vessels involved, and the r...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(01)00113-0
更新日期：2001-11-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.02.040
更新日期：2016-05-03 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：1997-07-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2020-12-24 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：1993-10-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2012.05.017
更新日期：2012-07-26 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2006-01-01 00:00:00
abstract：:Fatigue or stress fractures are an important clinical problem in humans as well as racehorses. An important question in this context is, when a bone experiences fatigue damage during extreme use, how much is it weakened compared to its original state? Since there are very limited data on this question and stress fract...
journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：1997-02-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2002-08-01 00:00:00
abstract：:Subchondral bone undecalcified samples, extracted from bovine femoral heads, are subjected to a direct tensile load. The Young's modulus of each sample is determined from repeated tests within the elastic limit. In a last test, the tensile load is increased up to the specimen failure, determining the ultimate tensile ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2000-09-01 00:00:00
abstract：:Developing effective therapeutics for osteoarthritis (OA) necessitates that such molecules can reach and target chondrocytes within articular cartilage. However, predicting how well very large therapeutic molecules diffuse through cartilage is often difficult, and the relationship between local transport mechanics for...
journal_title：Journal of biomechanics
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更新日期：2019-01-03 00:00:00
