Abstract：
:The question of whether the mechanical stiffness of a coronary bypass or that of a diseased coronary artery can have a significant effect on the hemodynamics in these vessels is addressed analytically, with emphasis on the effects of wave reflections. The analysis is based on a model of the vessels involved, and the results show the essential hemodynamic effects in each vessel. It is found that in the absence of a bypass graft, wave reflections resulting from a narrowing and stiffening of a diseased coronary artery have the effect of actually aiding the flow in the diseased vessel. In the presence of a bypass graft, however, the effects of wave reflections are reversed and become adverse to flow in both the bypass graft and the diseased coronary artery. A stiffer bypass moderates these effects and is therefore preferable to a more elastic bypass. The adverse effects also depend critically on the relative diameter of the bypass. Here the results indicate that a bypass of smaller diameter than that of the native coronary artery can moderate and even reverse the adverse effects of wave reflections resulting from the presence of the bypass.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Alderson H,Zamir Mdoi
10.1016/s0021-9290(01)00113-0keywords:
subject
Has Abstractpub_date
2001-11-01 00:00:00pages
1455-62issue
11eissn
0021-9290issn
1873-2380pii
S0021929001001130journal_volume
34pub_type
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