Abstract：
:Orthopaedic management of femoral head osteonecrosis is a common clinical problem for which there presently is no good solution. Current animal models are inappropriate to study potential new solutions, since it has been difficult to replicate the natural history of structural collapse seen in the human disorder. Recently, progression to collapse was obtained for cryogenically induced osteonecrosis in emus, although the lesions involved were imprecisely controlled in terms of size or location. A new cryo-insult probe is here reported for the purpose of delivering well-prescribed local thermal insults in this new animal model, while minimizing damage to non-targeted regions. Finite element analysis was used to elucidate the influence of operator-controlled parameters upon the temporal/spatial variation of the thermal field. The numerical formulation includes convective heat transfer attributable to tissue bed perfusion. The computational results agreed closely with the results of thermocouple recordings in a companion bench-top experiment. The cryo-insult probe successfully produced segmental lesions in the emu model of sizes comparable to the computed freeze front diameters.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Reed KL,Brown TD,Conzemius MGdoi
10.1016/s0021-9290(03)00154-4keywords:
subject
Has Abstractpub_date
2003-09-01 00:00:00pages
1317-26issue
9eissn
0021-9290issn
1873-2380pii
S0021929003001544journal_volume
36pub_type
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