Abstract:
:In this study, bulge inflation tests were used to characterize the failure response of 15 layers of human ascending thoracic aortic aneurysms (ATAA). Full field displacement data were collected during each of the mechanical tests using a digital image stereo-correlation (DIS-C) system. Using the collected displacement data, the local stress fields at burst were derived and the thickness evolution was estimated during the inflation tests. It was shown that rupture of the ATAA does not systematically occur at the location of maximum stress, but in a weakened zone of the tissue where the measured fields show strain localization and localized thinning of the wall. Our results are the first to show the existence of weakened zones in the aneurysmal tissue when rupture is imminent. An understanding these local rupture mechanics is necessary to improve clinical assessments of aneurysm rupture risk. Further studies must be performed to determine if these weakened zones can be detected in vivo using non-invasive techniques.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Romo A,Badel P,Duprey A,Favre JP,Avril Sdoi
10.1016/j.jbiomech.2013.12.012subject
Has Abstractpub_date
2014-02-07 00:00:00pages
607-16issue
3eissn
0021-9290issn
1873-2380pii
S0021-9290(13)00639-8journal_volume
47pub_type
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