Expedited patient-specific assessment of contact stress exposure in the ankle joint following definitive articular fracture reduction.

Abstract:

:Acute injury severity, altered joint kinematics, and joint incongruity are three important mechanical factors linked to post-traumatic osteoarthritis (PTOA). Finite element analysis (FEA) was previously used to assess the influence of increased contact stress due to joint incongruity on PTOA development. While promising agreement with PTOA development was seen, the inherent complexities of contact FEA limited the numbers of subjects that could be analyzed. Discrete element analysis (DEA) is a simplified methodology for contact stress computation, which idealizes contact surfaces as a bed of independent linear springs. In this study, DEA was explored as an expedited alternative to FEA contact stress exposure computation. DEA was compared to FEA using results from a previously completed validation study of two cadaveric human ankles, as well as a previous study of post-operative contact stress exposure in 11 patients with tibial plafond fracture. DEA-computed maximum contact stresses were within 19% of those experimentally measured, with 90% of the contact area having computed contact stress values within 1MPa of those measured. In the 11 fractured ankles, maximum contact stress and contact area differences between DEA and FEA were 0.85 ± 0.64 MPa and 22.5 ± 11.5mm(2). As a predictive measure for PTOA development, both DEA and FEA had 100% concordance with presence of OA (KL grade ≥ 2) and >95% concordance with KL grade at 2 years. These results support DEA as a reasonable alternative to FEA for computing contact stress exposures following surgical reduction of a tibial plafond fracture.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Kern AM,Anderson DD

doi

10.1016/j.jbiomech.2015.05.030

subject

Has Abstract

pub_date

2015-09-18 00:00:00

pages

3427-32

issue

12

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(15)00319-X

journal_volume

48

pub_type

杂志文章
  • Elbow and wrist joint contact forces during occupational pick and place activities.

    abstract::A three-dimensional, mathematical model of the elbow and wrist joints, including 15 muscle units, 3 ligaments and 4 joint forces, has been developed. A new strain gauge transducer has been developed to measure functional grip forces. The device measures radial forces divided into six components and forces of up to 250...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00184-0

    authors: Chadwick EK,Nicol AC

    更新日期:2000-05-01 00:00:00

  • Age-related distensibility and histology of the ascending aorta in elderly patients with acute aortic dissection.

    abstract::Degradation and fragmentation of elastic fibers in the media dilate the aortic wall excessively in patients with acute Stanford type A aortic dissection (AD). Such dilatation occurs not via aortic stiffening, which is diagnosed using imaging under physiological loading, but due to the abovementioned intrinsic changes ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.06.025

    authors: Yamada H,Sakata N,Wada H,Tashiro T,Tayama E

    更新日期:2015-09-18 00:00:00

  • Knee joint biomechanics of patients with unilateral total knee arthroplasty during stationary cycling.

    abstract::Stationary cycling is typically recommended following total knee arthroplasty (TKA) operations. However, knee joint biomechanics during cycling remains mostly unknown for TKA patients. Biomechanical differences between the replaced and non-replaced limb may inform applications of cycling in TKA rehabilitation. The pur...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2020.110111

    authors: Hummer E,Thorsen T,Weinhandl JT,Cates H,Zhang S

    更新日期:2021-01-22 00:00:00

  • Modeling methodology for defining a priori the hydrodynamics of a dynamic suspension bioreactor. Application to human induced pluripotent stem cell culture.

    abstract::Three-dimensional dynamic suspension is becoming an effective cell culture method for a wide range of bioprocesses, with an increasing number of bioreactors proposed for this purpose. The complex hydrodynamics establishing within these devices affects bioprocess outcomes and efficiency, and usually expensive in vitro ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2019.07.021

    authors: Isu G,Morbiducci U,De Nisco G,Kropp C,Marsano A,Deriu MA,Zweigerdt R,Audenino A,Massai D

    更新日期:2019-09-20 00:00:00

  • Sagittal plane rotation center of lower lumbar spine during a dynamic weight-lifting activity.

    abstract::This study investigated the center of rotation (COR) of the intervertebral segments of the lower lumbar spine (L4-L5 and L5-S1 segments) in sagittal plane during a weight-lifting (3.6 kg in each hand) extension activity performed with the pelvis constrained. Seven healthy subjects were studied using a dual fluoroscopi...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.12.029

    authors: Liu Z,Tsai TY,Wang S,Wu M,Zhong W,Li JS,Cha T,Wood K,Li G

    更新日期:2016-02-08 00:00:00

  • Alteration of blood hemorheologic properties during cerebral ischemia and reperfusion in rats.

    abstract::The cerebral ischemia and reperfusion rat model was employed in this experiment to study the rheological properties (i.e. viscosity, hematocrit, red blood cell deformability and thixotropic properties) of whole blood. The results of this study show that a significant relation exists between the duration of cerebral is...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(00)00180-9

    authors: Kuke D,Donghua L,Xiaoyan S,Yanjun Z

    更新日期:2001-02-01 00:00:00

  • Patient-specific bone modelling and remodelling simulation of hypoparathyroidism based on human iliac crest biopsies.

    abstract::We previously developed a load-adaptive bone modelling and remodelling simulation model that can predict changes in the bone micro-architecture as a result of changes in mechanical loading or cell activity. In combination with a novel algorithm to estimate loading conditions, this offers the possibility for patient-sp...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2012.06.031

    authors: Christen P,Ito K,Müller R,Rubin MR,Dempster DW,Bilezikian JP,van Rietbergen B

    更新日期:2012-09-21 00:00:00

  • Crushed bone grafts and a collagen membrane are not suitable for enhancing cartilage quality in the regeneration of osteochondral defects--an in vivo study in sheep.

    abstract::Hyaline joint cartilage has only a limited potential for self-repair. Some of the published techniques for osteochondral defect therapy try to improve that potential. In this study, it was hypothesised that one of those surgical techniques, the crushed transplanted bone graft together with a collagen membrane, acceler...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2007.02.021

    authors: Schell H,Lienau J,Kleemann RU,Schlichting K,Taylor WR,Weiler A,Duda GN

    更新日期:2007-01-01 00:00:00

  • Some mechanical properties of goose femoral cortical bone.

    abstract::The ultimate compressive strength and modulus of elasticity of femoral cortical bone from adult geese (Anser anser), were determined by sex and by quadrant by compressing small right circular cylinders which were 2.4 mm in height and 0.8 mm in diameter. The average ultimate compressive strength was 183 +/- 29 MPa. The...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(83)90108-2

    authors: McAlister GB,Moyle DD

    更新日期:1983-01-01 00:00:00

  • The association between negative muscle work and pedaling rate.

    abstract::The objective of this research was to use a pedal force decomposition approach to quantify the amount of negative muscular crank torque generated by a group of competitive cyclists across a range of pedaling rates. We hypothesized that negative muscular crank torque increases at high pedaling rates as a result of the ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00100-1

    authors: Neptune RR,Herzog W

    更新日期:1999-10-01 00:00:00

  • Sensitivity of dynamic simulations of gait and dynamometer experiments to hill muscle model parameters of knee flexors and extensors.

    abstract::We assessed and compared sensitivities of dynamic simulations to musculotendon (MT) parameters for gait and dynamometer experiments. Our aim with this comparison was to investigate whether dynamometer experiments could provide information about MT-parameters that are important to reliably study MT-function during gait...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.03.022

    authors: De Groote F,Van Campen A,Jonkers I,De Schutter J

    更新日期:2010-07-20 00:00:00

  • Effect of variable periodontal ligament thickness and its non-linear material properties on the location of a tooth's centre of resistance.

    abstract::In orthodontics, the 3D translational and rotational movement of a tooth is determined by the force-moment system applied and the location of the tooth's centre of resistance (CR). Because of the practical constraints of in-vivo experiments, the finite element (FE) method is commonly used to determine the CR. The obje...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2019.07.043

    authors: Schmidt F,Lapatki BG

    更新日期:2019-09-20 00:00:00

  • Center of pressure control for balance maintenance during lateral waist-pull perturbations in older adults.

    abstract::When balance is disturbed, location of the center of pressure (COP) contributes to a person's ability to recover from a perturbation. This study investigated COP control prior to first step lift-off (FSLO) during lateral perturbations in older non-fallers and fallers. 38 non-fallers and 16 fallers received lateral wai...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.02.012

    authors: Fujimoto M,Bair WN,Rogers MW

    更新日期:2015-04-13 00:00:00

  • Microdamage accumulation in the cement layer of hip replacements under flexural loading.

    abstract::Mechanical fatigue of bone cement leading to damage accumulation is implicated in the loosening of cemented hip components. Even though cracks have been identified in autopsy-retrieved mantles, damage accumulation by continuous growth and increase in number of microcracks has not yet been demonstrated experimentally. ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00018-4

    authors: McCormack BA,Prendergast PJ

    更新日期:1999-05-01 00:00:00

  • Regional dependency of the vascular smooth muscle cell contribution to the mechanical properties of the pig ascending aortic tissue.

    abstract:BACKGROUND:Dilation and dissection of aneurysmal ascending aortic tissues occur preferentially at the outer curvature of the vessel. In this study we hypothesize that the density and contractile properties of the vascular smooth muscle cells (VSMCs) of the pig ascending aorta (AA) are heterogeneous and could explain th...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.04.018

    authors: Tremblay D,Cartier R,Mongrain R,Leask RL

    更新日期:2010-08-26 00:00:00

  • Relationships between femoral fracture loads for two load configurations.

    abstract::Studies of proximal femoral strength usually involve one of two types of loading conditions, loading similar to joint loading during single-limb stance or loading simulating impact from a fall. When interpreting the results of studies involving only one of these load configurations, the question arises as to their app...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00202-x

    authors: Keyak JH

    更新日期:2000-04-01 00:00:00

  • Hysteresis measurements in intact human tendon.

    abstract::Mechanical hysteresis in tendons has traditionally been quantified from tensile testing of isolated specimens. Limitations associated with tendon displacement measurement and clamping, and uncertainties as to whether in vitro material represents intact tendon function necessitate measuring hysteresis under in vivo con...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(00)00130-5

    authors: Maganaris CN,Paul JP

    更新日期:2000-12-01 00:00:00

  • Non-invasive determination of cartilage thickness throughout joint surfaces using magnetic resonance imaging.

    abstract::Data on articular cartilage thickness in the living are important for the design for computer models, aimed at preoperatively assessing the effect of surgical procedures on joint contact and load transmission, and for the calculation of cartilage material properties from its deformational behavior as determined during...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(97)81146-3

    authors: Eckstein F,Adam C,Sittek H,Becker C,Milz S,Schulte E,Reiser M,Putz R

    更新日期:1997-03-01 00:00:00

  • Theoretical study of intracellular stress fiber orientation under cyclic deformation.

    abstract::We studied stress fiber orientation under a wide range of uniaxial cyclic deformations. We devised and validated a hypothesis consisting of two parts, as follows: (1) a stress fiber aligns to avoid a mechanical stimulus in the fiber direction under cyclic deformation. This means that, among all allowable directions, a...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(00)00114-7

    authors: Yamada H,Takemasa T,Yamaguchi T

    更新日期:2000-11-01 00:00:00

  • Synergistic action of static stretching and BMP-2 stimulation in the osteoblast differentiation of C2C12 myoblasts.

    abstract::Static stretching is a major type of mechanical stimuli utilized during distraction osteogenesis (DO), a general surgical method for the lengthening of bone. The molecular signals that drive the regenerative process in DO include a variety of cytokines. Among these, bone morphogenic protein (BMP, -2 and -4) has been r...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.08.006

    authors: Kim IS,Song YM,Cho TH,Kim JY,Weber FE,Hwang SJ

    更新日期:2009-12-11 00:00:00

  • Directional dependence of hydroxyapatite-collagen interactions on mechanics of collagen.

    abstract::Bone is a biological nanocomposite composed primarily of collagen and hydroxyapatite. The collagen molecules self-assemble to from a structure known as a fibril that comprises of about 85-95% of the total bone protein. In a fibril, the molecular level interactions at the interface between molecular collagen and hydrox...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.02.027

    authors: Katti DR,Pradhan SM,Katti KS

    更新日期:2010-06-18 00:00:00

  • A simulation study of vertical jumping from different starting postures.

    abstract::This paper addresses the question of whether maximal vertical jump height depends on initial jumping posture. A direct dynamics computer simulation approach was used to avoid subject preference and practice effects. The human body was modeled as four rigid segments connected by ideal hinge joints, with movement constr...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(96)00030-9

    authors: Selbie WS,Caldwell GE

    更新日期:1996-09-01 00:00:00

  • Comparison of different state space definitions for local dynamic stability analyses.

    abstract::Measures of local dynamic stability, such as the local divergence exponent (lambda*(s)) quantify how quickly small perturbations deviate from an attractor that defines the motion. When the governing equations of motion are unknown, an attractor can be reconstructed by defining an appropriate state space. However, stat...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.03.015

    authors: Gates DH,Dingwell JB

    更新日期:2009-06-19 00:00:00

  • Effects of different temperatures, velocities and loads on the gliding resistance of flexor digitorum profundus tendons in a human cadaver model.

    abstract::The purpose of this study was to investigate the effects of temperature, velocity and load on the gliding resistance (GR) of flexor digitorum profundus (FDP) tendons in a human cadaver model. A total of 40 FDP tendons from the index through small digits of ten human cadavers were tested to assess the effect of tempera...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2011.01.011

    authors: Moriya T,Chikenji T,Thoreson AR,Zhao C,An KN,Amadio PC

    更新日期:2011-04-29 00:00:00

  • Altered frontal and transverse plane tibiofemoral kinematics and patellofemoral malalignments during downhill gait in patients with mixed knee osteoarthritis.

    abstract::Patients with knee osteoarthritis often present with signs of mixed tibiofemoral and patellofemoral joint disease. It has been suggested that altered frontal and transverse plane knee joint mechanics play a key role in compartment-specific patterns of knee osteoarthritis, but in-vivo evidence in support of this premis...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.05.015

    authors: Farrokhi S,Meholic B,Chuang WN,Gustafson JA,Fitzgerald GK,Tashman S

    更新日期:2015-07-16 00:00:00

  • Effect of chronic idiopathic low back pain on the kinetic gait characteristics in different foot masks.

    abstract::Identification of kinetic variables in different masks of foot is important for the evaluation and treatment of chronic low back pain. The aim of this study was to investigate the effect of chronic idiopathic low back pain on kinetic variables of gait in different foot masks. 11 idiopathic chronic low back pain patien...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2018.08.013

    authors: Yazdani S,Dizji E,Alizadeh F,Hassanlouei H

    更新日期:2018-10-05 00:00:00

  • Mechanical mechanisms of thrombosis in intact bent microvessels of rat mesentery.

    abstract::The hypothesis that thrombus can be induced by localized shear stresses/rates, such as in the bent/stretched microvessels, was tested both experimentally and computationally. Our newly designed in vivo experiments were performed on the microvessels (post-capillary venules, 20-50 microm diameter) of rat mesentery. Thes...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2008.06.013

    authors: Liu Q,Mirc D,Fu BM

    更新日期:2008-08-28 00:00:00

  • 3D Imaging of vascular networks for biophysical modeling of perfusion distribution within the heart.

    abstract::One of the main determinants of perfusion distribution within an organ is the structure of its vascular network. Past studies were based on angiography or corrosion casting and lacked quantitative three dimensional, 3D, representation. Based on branching rules and other properties derived from such imaging, 3D vascula...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbiomech.2012.11.027

    authors: van den Wijngaard JP,Schwarz JC,van Horssen P,van Lier MG,Dobbe JG,Spaan JA,Siebes M

    更新日期:2013-01-18 00:00:00

  • A Hill type model of rat medial gastrocnemius muscle that accounts for shortening history effects.

    abstract::The aim of the present study was to develop a Hill type muscle model that accounts for the effects of shortening history. For this purpose, a function was derived that relates force depression to starting length, shortening amplitude and contraction velocity. History parameters were determined from short-range isokine...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(98)00048-7

    authors: Meijer K,Grootenboer HJ,Koopman HF,van der Linden BJ,Huijing PA

    更新日期:1998-06-01 00:00:00

  • In situ fibril stretch and sliding is location-dependent in mouse supraspinatus tendons.

    abstract::Tendons are able to transmit high loads efficiently due to their finely optimized hierarchical collagen structure. Two mechanisms by which tendons respond to load are collagen fibril sliding and deformation (stretch). Although many studies have demonstrated that regional variations in tendon structure, composition, an...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2014.10.029

    authors: Connizzo BK,Sarver JJ,Han L,Soslowsky LJ

    更新日期:2014-12-18 00:00:00