Abstract：
:A pair of finite element models has been employed to study the interaction of blood flow with the operation of the aortic valve. A three-dimensional model of the left ventricle with applied wall displacements has been used to generate data for the spatially and time-varying blood velocity profile across the aortic aperture. These data have been used as the inlet loading conditions in a three-dimensional model of the aortic valve and its surrounding structures. Both models involve fluid-structure interaction and simulate the cardiac cycle as a dynamic event. Confidence in the models was obtained by comparison with data obtained in a pulse duplicator. The results show a circulatory flow being generated in the ventricle which produces a substantially axial flow through the aortic aperture. The aortic valve behaves in an essentially symmetric way under the action of this flow, so that the pressure difference across the leaflets is approximately uniform. This work supports the use of spatially uniform but temporally variable pressure distributions across the leaflets in dry or structural models of aortic valves. The study is a major advance through its use of truly three-dimensional geometry, spatially non-uniform loading conditions for the valve leaflets and the successful modelling of progressive contact of the leaflets in a fluid environment.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Carmody CJ,Burriesci G,Howard IC,Patterson EAdoi
10.1016/j.jbiomech.2004.10.038keywords:
subject
Has Abstractpub_date
2006-01-01 00:00:00pages
158-69issue
1eissn
0021-9290issn
1873-2380pii
S0021-9290(04)00565-2journal_volume
39pub_type
杂志文章abstract：:Bone remodelling is a dynamic process that requires the coordinated interaction of osteocytes, osteoblasts, and osteoclasts, collaborating in basic multicellular units (BMUs). Communication between these cells can be by extracellular soluble molecules as well as directly propagating intercellular signalling molecules....
journal_title：Journal of biomechanics
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abstract：:Controlling dynamic interactions between the lower limb and ground is important for skilled locomotion and may influence injury risk in athletes. It is well known that female athletes sustain anterior cruciate ligament (ACL) tears at higher rates than male athletes, and exhibit lower extremity biomechanics thought to ...
journal_title：Journal of biomechanics
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abstract：:Different standing postures could potentially influence trunk biomechanics during task performance. The current study investigated how foot placement, especially stance width and foot angle influenced lumbopelvic rhythm during sagittal trunk flexion motion. Ten participants performed pace controlled sagittally symmetr...
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.08.002
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.03.022
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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pub_type： 杂志文章
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更新日期：2020-07-17 00:00:00
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
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journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2006-01-01 00:00:00
abstract：:Rigid body attitude and single-joint kinematics are typically expressed using three Cardan angles which represent rotations in anatomical planes. It was recently shown in the Biomechanics literature that Cardan angles inaccurately estimate true mean attitude due to an important mathematical inadequacy: attitude under-...
journal_title：Journal of biomechanics
pub_type： 杂志文章
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