Jet collisions and vortex reversal in the human left ventricle.

Abstract:

:Unnatural dynamics of the notorious vortex in the left ventricle is often associated with cardiac disease. Understanding how different cardiac diseases alter the flow physics in the left ventricle may therefore provide a powerful tool for disease detection. In this work, the fluid dynamics in the left ventricle subject to different severities of aortic regurgitation is experimentally investigated by performing time-resolved particle image velocimetry in a left heart duplicator. Diastolic vortex reversal was observed in the left ventricle accompanied by an increase in viscous energy dissipation. Vortex dynamics and energy dissipation may provide useful insights on sub-optimal flow patterns in the left ventricle.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Di Labbio G,Kadem L

doi

10.1016/j.jbiomech.2018.07.023

subject

Has Abstract

pub_date

2018-09-10 00:00:00

pages

155-160

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(18)30533-5

journal_volume

78

pub_type

杂志文章
  • Multiple-step model-experiment matching allows precise definition of dynamical leg parameters in human running.

    abstract::The spring-loaded inverted pendulum (SLIP) model is a well established model for describing bouncy gaits like human running. The notion of spring-like leg behavior has led many researchers to compute the corresponding parameters, predominantly stiffness, in various experimental setups and in various ways. However, dif...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2012.06.030

    authors: Ludwig C,Grimmer S,Seyfarth A,Maus HM

    更新日期:2012-09-21 00:00:00

  • Force response of the fingertip pulp to repeated compression--effects of loading rate, loading angle and anthropometry.

    abstract::Repeated loading of the fingertips has been postulated to contribute to tendon and nerve disorders at the wrist during activities associated with prolonged fingertip loading such as typing. To fully understand the pathomechanics of these soft tissue disorders, the role of the fingertip pulp in attenuating the applied ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(97)00065-1

    authors: Serina ER,Mote CD Jr,Rempel D

    更新日期:1997-10-01 00:00:00

  • An energy 'sources' and 'fractions' approach to the mechanical energy expenditure problem--IV. Criticism of the concept of 'energy transfers within and between links'.

    abstract::The methods of evaluation of mechanical energy economy during human movement based on the calculation of three different values of work (Wwb, Ww, Wn), corresponding to three hypothetical types of energy exchange, are subject to criticism. Only the value of work, Wwb, calculated under the assumption of energy transfers...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(86)90006-0

    authors: Aleshinsky SY

    更新日期:1986-01-01 00:00:00

  • Towards a viscoelastic model for the unfused midpalatal suture: development and validation using the midsagittal suture in New Zealand white rabbits.

    abstract::Maxillary expansion treatment is a commonly used procedure by orthodontists to widen a patient's upper jaw. As this is typically performed in adolescent patients, the midpalatal suture, connective tissue adjoining the two maxilla halves, remains unfused. Studies that have investigated patient response to expansion tre...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2013.04.011

    authors: Romanyk DL,Liu SS,Lipsett MG,Toogood RW,Lagravère MO,Major PW,Carey JP

    更新日期:2013-06-21 00:00:00

  • In vivo biomechanical behavior of the human heel pad during the stance phase of gait.

    abstract::A technique is introduced for simultaneous measurements of the heel pad tissue deformation and the heel-ground contact stresses developing during the stance phase of gait. Subjects walked upon a gait platform integrating the contact pressure display optical method for plantar pressure measurements and a digital radiog...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(01)00143-9

    authors: Gefen A,Megido-Ravid M,Itzchak Y

    更新日期:2001-12-01 00:00:00

  • Two mathematical models explain the variation in cystometrograms of obstructed urinary bladders.

    abstract::Overdistension of the urinary bladder, secondary to outlet obstruction, causes cellular changes in the bladder wall, including hypertrophy of the smooth muscle cells, which increase bladder mass. To investigate the effects of increased mass on the cystometrogram (CMG), we have developed two mathematical models. In the...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:

    authors: Damaser MS,Lehman SL

    更新日期:1996-12-01 00:00:00

  • Variability observed in mechano-regulated in vivo tissue differentiation can be explained by variation in cell mechano-sensitivity.

    abstract::Computational simulations of tissue differentiation have been able to capture the main aspects of tissue formation/regeneration observed in animal experiments-except for the considerable degree of variability reported. Understanding and modelling the source of this variability is crucial if computational tools are to ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2011.02.003

    authors: Khayyeri H,Checa S,Tägil M,Aspenberg P,Prendergast PJ

    更新日期:2011-04-07 00:00:00

  • An analysis of the squeeze-film lubrication mechanism for articular cartilage.

    abstract::An asymptotic analysis of a lubrication problem is presented for a model of articular cartilage and synovial fluid under the squeeze-film condition. This model is based upon the following constitutive assumptions: (1) articular cartilage is a linear porous-permeable biphasic material filled with a linearly viscous flu...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(92)90024-u

    authors: Hou JS,Mow VC,Lai WM,Holmes MH

    更新日期:1992-03-01 00:00:00

  • Velocity profiles in annular perfusion chamber measured by laser-Doppler velocimetry.

    abstract::p6e fluid flow in the annular perfusion chamber of Baumgartner developed to study platelet vessel wall interaction was examined with laser-Doppler velocimetry. A laminar and stable flow with a Reynolds number of less than or equal to 50 was measured at flow rates up to 3 ml s-1. No turbulence was found. The wall shear...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(84)90081-2

    authors: Aarts PA,van Broek JA,Kuiken GD,Sixma JJ,Heethaar RM

    更新日期:1984-01-01 00:00:00

  • Fracture analysis for biological materials with an expanded cohesive zone model.

    abstract::In this study, a theoretical framework for simulation of fracture of bone and bone-like materials is provided. An expanded cohesive zone model with thermodynamically consistent framework has been proposed and used to investigate the crack growth resistance of bone and bone-like materials. The reversible elastic deform...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2014.04.054

    authors: An B,Zhao X,Arola D,Zhang D

    更新日期:2014-07-18 00:00:00

  • Statistical osteoporosis models using composite finite elements: a parameter study.

    abstract::Osteoporosis is a widely spread disease with severe consequences for patients and high costs for health care systems. The disease is characterised by a loss of bone mass which induces a loss of mechanical performance and structural integrity. It was found that transverse trabeculae are thinned and perforated while ver...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.06.017

    authors: Wolfram U,Schwen LO,Simon U,Rumpf M,Wilke HJ

    更新日期:2009-09-18 00:00:00

  • The vesico-urethral pressuregram analysis of urethral function under stress.

    abstract::About one-third of older multiparous women are prone to stress urinary incontinence (SUI): unwanted urine loss during activities which suddenly raise intra-abdominal pressure. In this paper we describe and test a method for visualizing and analyzing the function of the urinary continence control system (CCS) under str...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(97)81291-2

    authors: Kim KJ,Ashton-Miller JA,Strohbehn K,DeLancey JO,Schultz AB

    更新日期:1997-01-01 00:00:00

  • Circumferentially flexible vascular grafts.

    abstract::An arterial graft with a corrugated cylindrical cross-section has been proposed as a partial solution to the problem of elastic stiffness mismatch between conventional grafts and arterial tissue (Trescony et al., 1994, US Patent 5,282, 847 (granted February 1 1994)). A two-dimensional ring theory model and a finite el...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(98)00084-0

    authors: Stump DM,Hart VG,Tuttle SL

    更新日期:1998-08-01 00:00:00

  • The measurement of body segment inertial parameters using dual energy X-ray absorptiometry.

    abstract::Accurate body segment parameter (BSP) information is required for dynamic analyses of motion and the current methods available for obtaining these BSPs have been criticized. The purpose of this study was to determine whether dual energy X-ray absorptiometry (DXA) could accurately measure the BSPs of scanned objects an...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(02)00227-0

    authors: Durkin JL,Dowling JJ,Andrews DM

    更新日期:2002-12-01 00:00:00

  • The behavior of adaptive bone-remodeling simulation models.

    abstract::The process of adaptive bone remodeling can be described mathematically and simulated in a computer model, integrated with the finite element method. In the model discussed here, cortical and trabecular bone are described as continuous materials with variable density. The remodeling rule applied to simulate the remode...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(92)90056-7

    authors: Weinans H,Huiskes R,Grootenboer HJ

    更新日期:1992-12-01 00:00:00

  • Estimating severity of sideways fall using a generic multi linear regression model based on kinematic input variables.

    abstract::Many research groups have studied fall impact mechanics to understand how fall severity can be reduced to prevent hip fractures. Yet, direct impact force measurements with force plates are restricted to a very limited repertoire of experimental falls. The purpose of this study was to develop a generic model for estima...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2017.01.033

    authors: van der Zijden AM,Groen BE,Tanck E,Nienhuis B,Verdonschot N,Weerdesteyn V

    更新日期:2017-03-21 00:00:00

  • Endothelialization of over- and undersized flow-diverter stents at covered vessel side branches: An in vivo and in silico study.

    abstract::Although flow-diverting devices are promising treatment options for intracranial aneurysms, jailed side branches might occlude leading to insufficient blood supply. Especially differences in the local stent strut compression may have a drastic influence on subsequent endothelialization. To investigate the outcome of d...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.10.047

    authors: Berg P,Iosif C,Ponsonnard S,Yardin C,Janiga G,Mounayer C

    更新日期:2016-01-04 00:00:00

  • Dynamic shear behavior of mandibular condylar cartilage is dependent on testing direction.

    abstract::Little information is available on the direction-dependency of shear behavior in mandibular condylar cartilage. Therefore, we tested the hypothesis that such a dependency of the dynamic shear properties is present in mandibular condylar cartilage. From each of 17 condyles, two cartilage-bone plugs were dissected and t...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2007.12.012

    authors: Tanaka E,Iwabuchi Y,Rego EB,Koolstra JH,Yamano E,Hasegawa T,Kawazoe A,Kawai N,Tanne K

    更新日期:2008-01-01 00:00:00

  • Modeling the mechanical properties of liver fibrosis in rats.

    abstract::The progression of liver fibrosis changes the biomechanical properties of liver tissue. This study characterized and compared different liver fibrosis stages in rats in terms of viscoelasticity. Three viscoelastic models, the Voigt, Maxwell, and Zener models, were applied to experimental data from rheometer tests and ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2016.03.013

    authors: Zhu Y,Chen X,Zhang X,Chen S,Shen Y,Song L

    更新日期:2016-06-14 00:00:00

  • Effects of mechanical loading patterns, bone graft, and proximity to periosteum on bone defect healing.

    abstract::The goal of this study is to elucidate whether mechanobiological factors, including mechanical loading patterns, presence of bone graft, and proximity to the periosteum, correlate to de novo tissue generation and healing in critical sized long bone defects, which are enveloped by periosteum in situ and are bridged at ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.06.026

    authors: Knothe UR,Dolejs S,Matthew Miller R,Knothe Tate ML

    更新日期:2010-10-19 00:00:00

  • Dynamics of the human masticatory muscles during a jaw open-close movement.

    abstract::The movements of the human jaw are controlled by the forces produced by the masticatory muscles. As the jaw moves, these muscles change in length and their force producing units, the sarcomeres, change in length simultaneously. The lengths and length changes of the sarcomeres are determinants for the forces they are a...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(97)00047-x

    authors: Koolstra JH,van Eijden TM

    更新日期:1997-09-01 00:00:00

  • Predicting timing of foot strike during running, independent of striking technique, using principal component analysis of joint angles.

    abstract::As 3-dimensional (3D) motion-capture for clinical gait analysis continues to evolve, new methods must be developed to improve the detection of gait cycle events based on kinematic data. Recently, the application of principal component analysis (PCA) to gait data has shown promise in detecting important biomechanical f...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2014.06.009

    authors: Osis ST,Hettinga BA,Leitch J,Ferber R

    更新日期:2014-08-22 00:00:00

  • Three-dimensional osteometric scaling and normative modelling of skeletal segments.

    abstract::Many analytical biomechanics methods require extensive three-dimensional descriptions of anatomical geometry. In particular, researchers requiring the three-dimensional coordinates of specific boney landmarks (e.g. tendon and ligament attachments) are often forced to extrapolate such measurements from an experimental ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(82)90249-4

    authors: Sommer HJ 3rd,Miller NR,Pijanowski GJ

    更新日期:1982-01-01 00:00:00

  • Phalanx force magnitude and trajectory deviation increased during power grip with an increased coefficient of friction at the hand-object interface.

    abstract::This study examined the effect of friction between the hand and grip surface on a person's grip strategy and force generation capacity. Twelve young healthy adults performed power grip exertions on an instrumented vertical cylinder with the maximum and 50% of maximum efforts (far above the grip force required to hold ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2011.03.020

    authors: Enders LR,Seo NJ

    更新日期:2011-05-17 00:00:00

  • Effects of intervertebral disc lesion and multifidus muscle resection on the structure of the lumbar intervertebral discs and paraspinal musculature of the rat.

    abstract::The aim of this study was to investigate whether elimination of multifidus muscle in rats causes intervertebral disc (IVD) degeneration similar to that found after IVD lesion. Data were obtained from 36 male Wistar rats randomly assigned to one of three groups: (i) IVD lesion, in which the L4/L5 IVD was stabbed; (ii) ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2018.01.004

    authors: Maas H,Noort W,Hodges PW,van Dieën J

    更新日期:2018-03-21 00:00:00

  • Experimental study of physiological pulsatile flow past valve prosthesis in a model of human aorta--II. Tilting disc valves and the effect of orientation.

    abstract::In Part II of this two paper sequence, pulsatile flow development past a tilting disc valve in a model human aorta has been studied using quantitative laser Doppler techniques. The valve was mounted in three different orientations with respect to the aortic root in this study. Under pulsatile flow, the region of flow ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(85)90052-1

    authors: Chandran KB,Khalighi B,Chen CJ

    更新日期:1985-01-01 00:00:00

  • Numerical simulation of unsteady laminar flow through a tilting disk heart valve: prediction of vortex shedding.

    abstract::Heart valves induce flow disturbances which play a role in blood cell activation and damage, but questions of the magnitude and spatial distribution of fluid stresses (wall shear stress and turbulent stress) cannot be readily addressed with current experimental techniques. Therefore, a numerical simulation procedure f...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(94)90015-9

    authors: Huang ZJ,Merkle CL,Abdallah S,Tarbell JM

    更新日期:1994-04-01 00:00:00

  • Experimentally verified mathematical approach for the prediction of force developed by motor units at variable frequency stimulation patterns.

    abstract::During normal daily activity, muscle motor units (MUs) develop unfused tetanic contractions evoked by trains of motoneuronal firings at variable interpulse intervals (IPIs). The mechanical responses of a MU to successive impulses are not identical. The aim of this study was to develop a mathematical approach for the p...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.01.034

    authors: Raikova R,Rusev R,Drzymała-Celichowska H,Krutki P,Aladjov H,Celichowski J

    更新日期:2010-05-28 00:00:00

  • A puzzle assembly strategy for fabrication of large engineered cartilage tissue constructs.

    abstract::Engineering of large articular cartilage tissue constructs remains a challenge as tissue growth is limited by nutrient diffusion. Here, a novel strategy is investigated, generating large constructs through the assembly of individually cultured, interlocking, smaller puzzle-shaped subunits. These constructs can be engi...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2016.01.023

    authors: Nover AB,Jones BK,Yu WT,Donovan DS,Podolnick JD,Cook JL,Ateshian GA,Hung CT

    更新日期:2016-03-21 00:00:00

  • A laser-aligned method for anthropometry of hands.

    abstract::We have developed a laser-aligned measuring device to facilitate the measurement of linear hand dimensions. Our objective has been to make a simple, clinically applicable device for anthropometry of the hands in patients with arthritis in order to gauge the progression of hand deformities. The system provides an alter...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(03)00121-0

    authors: Highton J,Davidson P,Markham V

    更新日期:2003-09-01 00:00:00