Abstract：
:Overdistension of the urinary bladder, secondary to outlet obstruction, causes cellular changes in the bladder wall, including hypertrophy of the smooth muscle cells, which increase bladder mass. To investigate the effects of increased mass on the cystometrogram (CMG), we have developed two mathematical models. In the first model, we assume that mass is added such that the largest bladder volume at zero transmural pressure, the zero pressure volume (ZPV), is constant, It predicts increased pressures and decreased compliance in the CMG. In the second model, we assume that both mass and ZPV increase proportionally. It predicts unchanged pressures, increased compliance, and increased capacity in the CMG. These results allow use to divide animal experiments in the literature into two groups. Cystometrograms performed on animals that have had outlet obstruction induced by a cuff method, inducing a small increase in mass, belong to the first group: hypertrophy with no change in ZPV. Cystometrograms performed on animals that have had outlet obstruction induced by a ligature method, inducing a large increase in mass, belong to the second group: hypertrophy with increased ZPV. We conclude that increased ZPV results from a more severe obstruction which is indicated by the increased capacity and compliance.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Damaser MS,Lehman SLsubject
Has Abstractpub_date
1996-12-01 00:00:00pages
1615-9issue
12eissn
0021-9290issn
1873-2380pii
0021-9290(96)00091-7journal_volume
29pub_type
杂志文章abstract：:The hemodynamic influence of vessel shape such as bifurcation angle is not fully understood with clinical and quantitative observations being equivocal. The aim of this study is to use computational modeling to study the hemodynamic effect of shape characteristics, in particular bifurcation angle (BA), for non-stented...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.03.038
更新日期：2016-06-14 00:00:00
abstract：:When the foot impacts the ground in running, large forces and loading rates can arise that may contribute to the development of overuse injuries. Investigating which biomechanical factors contribute to these impact loads and loading rates in running could assist clinicians in developing strategies to reduce these load...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2013.10.026
更新日期：2014-01-03 00:00:00
abstract：:This study was aimed at investigating the intersegmental coordination of six older adults while managing unexpected slippages delivered during steady walking, and wearing an Active Pelvis Orthosis (APO). The APO was setup either to assist volunteers at the hip levels during balance loss or to be transparent. The Plana...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.01.003
更新日期：2019-03-06 00:00:00
abstract：:Wall thickness and medial line radii of an in vitro canine heart are measured. These data are assumed to be characteristic of the in vivo ventricles subject to zero pressure, and in the absence of filling. The myocardium is taken to be homogeneous, isotropic, non-linearly elastic, and incompressible. The right ventric...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(82)90171-3
更新日期：1982-01-01 00:00:00
abstract：:Healthy patellofemoral (PF) joint mechanics are critical to optimal function of the knee joint. Patellar maltracking may lead to large joint reaction loads and high stresses on the articular cartilage, increasing the risk of cartilage wear and the onset of osteoarthritis. While the mechanical sources of PF joint dysfu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.12.020
更新日期：2016-01-25 00:00:00
abstract：:In this paper, we measured the maximum isometric force at the hand in eight directions in the horizontal plane and at five positions in the workplace. These endpoint forces were the result of shoulder horizontal adduction/abduction and elbow flexion/extension torques. We found that the normalized maximum forces of all...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2005.01.004
更新日期：2006-01-01 00:00:00
abstract：:Confinement of the heel due to the counter of the shoe is believed to influence heel pad biomechanics. Using a two-dimensional finite element model of the heel pad and shoe during a simulation of static standing, the aim of this study was to quantify the potential effect of confinement on internal heel pad stress. Non...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.01.004
更新日期：2007-01-01 00:00:00
abstract：:A computational fluid dynamics model for the analysis of the bileaflet mechanical heart valve closure process is presented. The objective of the study is to demonstrate the ability of the numerical model to simulate the leaflet motion during the closing phase in order to investigate the closure fluid dynamics and to e...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(02)00056-8
更新日期：2002-07-01 00:00:00
abstract：:Polyethylene remains the most popular bearing material for total knee arthroplasty (TKA). Despite its widespread use, wear continue to be one of major factors implicated in revision surgery. Sliding distance, cross-shear, and contact stress are the major factors influencing polyethylene wear. As previous studies have ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.06.009
更新日期：2018-08-22 00:00:00
abstract：:The active control of the trunk plays an important role in frontal plane gait stability. We characterized trunk control in response to different step widths using a novel feedback system and examined the different effects of wide and narrow step widths as they each present unique task demands. Twenty healthy young adu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.110135
更新日期：2021-01-04 00:00:00
abstract：:The contribution of this paper is a bivariate optimization of cycling performance. Relying on a biomechanical model of the lower limb, a cost function derived from the joint moments developed during cycling is computed. At constant average power, both pedalling rate (i.e. rpm) and crank arm length are systematically v...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(88)90016-4
更新日期：1988-01-01 00:00:00
abstract：:The understanding of impact mechanics during locomotion is important for research within the fields of injury prevention and footwear design. Instrumented missiles offer a worthy solution to the lack of control inherent in in vivo activities and to the isolated nature of tissue studies. However, missiles cannot mimic ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(95)00002-y
更新日期：1995-09-01 00:00:00
abstract：:Age-related changes in bone quality are mainly manifested in the reduced toughness. Since the post-yield deformation of bone is realized through microdamage formation (e.g., microcracking and diffuse damage), it is necessary to understand the mechanism of microdamage formation in bone in order to elucidate underlying ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.01.009
更新日期：2006-01-01 00:00:00
abstract：:This paper presents a method for analyzing and comparing numerically Saphenous Vein Grafts (SVGs) following Coronary Artery Bypass Graft surgery (CABG). The method analyses the flow dynamics inside vein grafts with and without supporting using Venous External Scaffolding Technology (VEST). The numerical method uses pa...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.03.011
更新日期：2015-07-16 00:00:00
abstract：:Static stretching is a major type of mechanical stimuli utilized during distraction osteogenesis (DO), a general surgical method for the lengthening of bone. The molecular signals that drive the regenerative process in DO include a variety of cytokines. Among these, bone morphogenic protein (BMP, -2 and -4) has been r...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.08.006
更新日期：2009-12-11 00:00:00
abstract：:A device is described for measuring strength and power outputs of dynamic vertical lifts between heights of 0.4 and 2.2 m. The device is safe, robust, and easily transportable. It consists of a water-filled tube 2 m high and 200 mm internal diameter. The subject pulls vertically on a handle which is connected with fle...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(96)00155-8
更新日期：1997-04-01 00:00:00
abstract：:Inertial measurement unit systems (IMU) are increasingly used in sports. However, no algorithm evaluating the instantaneous swimming velocity has been validated on the four swimming strokes, or on dive start. Our objective is to develop and validate a new method to measure instantaneous swimming velocity on athletes p...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2021.110261
更新日期：2021-01-19 00:00:00
abstract：:Considering that an athlete performs at-risk sports activities countless times throughout the course of his or her career prior to the instance of anterior cruciate ligament (ACL) injury, one may conclude that non-contact ACL injury is a rare event. Nevertheless, the overall number of non-contact ACL injuries, both in...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.11.013
更新日期：2011-02-24 00:00:00
abstract：:Numerical differentiation of noisy measurement data represents a problem frequently encountered in the field of gait analysis. There are two major determinants of the quality in calculated derivatives, namely the quality of the measurement data and the quality of the used differentiation technique. The quality of the ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(82)90041-0
更新日期：1982-01-01 00:00:00
abstract：:One of the most popular methods to fabricate biomedical microfluidic devices is by using a soft-lithography technique. However, the fabrication of the moulds to produce microfluidic devices, such as SU-8 moulds, usually requires a cleanroom environment that can be quite costly. Therefore, many efforts have been made t...
journal_title：Journal of biomechanics
pub_type： 杂志文章,评审
doi：10.1016/j.jbiomech.2015.11.031
更新日期：2016-07-26 00:00:00
abstract：:The maximum tetanic tension of skeletal muscle (P(0)) is often estimated based on calculation of physiological cross-sectional area (PCSA). PCSA depends on muscle volume, pennation angle, and fiber length. Studies documenting PCSA in fixed human muscles usually compute muscle volume by dividing muscle mass by density....
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2004.10.001
更新日期：2005-11-01 00:00:00
abstract：:Clinical trials have shown overlapping bare-metal stents provoke effective thrombus clot within the aneurysm sac and shrinkage of the aneurysm by directly regulating the hemodynamics. To gain insight into the hemodynamic mechanism of the technique, three cases of simplified thoracic aortic aneurysm models (with no ste...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.03.028
更新日期：2015-07-16 00:00:00
abstract：:In this work we propose a method to estimate the elastic properties of the extracellular matrix of articular cartilage, once the elastic properties of the chondrocytes and the whole tissue are known. The influence of the elastic properties of the tissue and the cell concentration on the estimated elastic properties of...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(03)00280-x
更新日期：2004-03-01 00:00:00
abstract：:The six non-interacting modes for stress, strain and energy in an orthotropic elastic model of human femoral cortical bone tissue are discussed and illustrated. The stress and strain modes are illustrated using the representation of the stress and strain fields around a circular hole in a flat plate of cortical bone s...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(91)90311-a
更新日期：1991-01-01 00:00:00
abstract：:This paper describes a method for adjusting biomechanics platform measures of sway for loss of balance. Area and velocity measures of sway were determined in forty-seven elderly women, in double and single leg stance, first with their eyes open, then closed. Subjects were rarely able to complete 10 s trials during sin...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(90)90025-x
更新日期：1990-01-01 00:00:00
abstract：:This paper presents a practical and effective approach to the calibration of instrumented spatial linkages for biomechanical applications. A 6-DOF mechanical linkage with rotational transducers is designed and in-house manufactured for this purpose. In order to assess the validity of the proposed calibration technique...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2006.06.021
更新日期：2007-01-01 00:00:00
abstract：:Dynamic stabilization devices have been introduced to clinics as an alternative to rigid fixation. The stiffness of these devices varies widely, whereas the optimal stiffness, achieving a predefined stabilization of the spine, is unknown. This study was focused on the determination of stiffness values for posterior st...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.10.005
更新日期：2009-01-05 00:00:00
abstract：:To prevent spinal cord injury, optimize treatments for it, and better understand spinal cord pathologies such as spondylotic myelopathy, the interaction between the spinal column and the spinal cord during injury and pathology must be understood. The spinal cord is a complex and very soft tissue that changes propertie...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.01.036
更新日期：2009-05-11 00:00:00
abstract：:The purpose of this study was to gain an improved understanding of the mechanical behavior of the intervertebral disc in the presence and absence of the vertebral endplates. Mechanical behaviors of rat caudal motion segments, vertebrae and isolated disc explants under two different permeability conditions were investi...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.11.013
更新日期：2007-01-01 00:00:00
abstract：:The structure and function of the renal artery ostium flow diverter on the caudal side of the renal branch point were previously reported; in this study, we further evaluate the diverter׳s possible functions. The protrusion of this structure into the abdominal aorta suggests that the diverter may preferentially direct...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.03.006
更新日期：2014-05-07 00:00:00
