Validation of predicted patellofemoral mechanics in a finite element model of the healthy and cruciate-deficient knee.

Abstract:

:Healthy patellofemoral (PF) joint mechanics are critical to optimal function of the knee joint. Patellar maltracking may lead to large joint reaction loads and high stresses on the articular cartilage, increasing the risk of cartilage wear and the onset of osteoarthritis. While the mechanical sources of PF joint dysfunction are not well understood, links have been established between PF tracking and abnormal kinematics of the tibiofemoral (TF) joint, specifically following cruciate ligament injury and repair. The objective of this study was to create a validated finite element (FE) representation of the PF joint in order to predict PF kinematics and quadriceps force across healthy and pathological specimens. Measurements from a series of dynamic in-vitro cadaveric experiments were used to develop finite element models of the knee for three specimens. Specimens were loaded under intact, ACL-resected and both ACL and PCL-resected conditions. Finite element models of each specimen were constructed and calibrated to the outputs of the intact knee condition, and subsequently used to predict PF kinematics, contact mechanics, quadriceps force, patellar tendon moment arm and patellar tendon angle of the cruciate resected conditions. Model results for the intact and cruciate resected trials successfully matched experimental kinematics (avg. RMSE 4.0°, 3.1mm) and peak quadriceps forces (avg. difference 5.6%). Cruciate resections demonstrated either increased patellar tendon loads or increased joint reaction forces. The current study advances the standard for evaluation of PF mechanics through direct validation of cruciate-resected conditions including specimen-specific representations of PF anatomy.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Ali AA,Shalhoub SS,Cyr AJ,Fitzpatrick CK,Maletsky LP,Rullkoetter PJ,Shelburne KB

doi

10.1016/j.jbiomech.2015.12.020

subject

Has Abstract

pub_date

2016-01-25 00:00:00

pages

302-9

issue

2

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(15)00726-5

journal_volume

49

pub_type

杂志文章
  • Validation of a bone loading estimation algorithm for patient-specific bone remodelling simulations.

    abstract::Patient-specific simulations of bone remodelling could enable predicting how bone micro-structural integrity would be affected by bone diseases, drugs or other factors, and, ultimately could help clinicians to improve their prognoses. To simulate load-adaptive remodelling, however, knowledge about the physiological ex...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2012.12.012

    authors: Christen P,Ito K,Santos AA,Müller R,Bert van Rietbergen

    更新日期:2013-03-15 00:00:00

  • Fatigue damage of human tendons.

    abstract::The study was designed to examine the effects of partial fatigue on specific mechanical parameters which characterise human tendons in vitro. Specimens prepared from 12 intact Extensor digitorum longus tendons of the foot were subjected to partial fatigue, equivalent to 25% of the median fatigue life, by a cyclic squa...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(01)00177-4

    authors: Schechtman H,Bader DL

    更新日期:2002-03-01 00:00:00

  • Parametric and subject-specific finite element modelling of the lower cervical spine. Influence of geometrical parameters on the motion patterns.

    abstract::Morphometrical and postural features of the cervical spine are supposed to significantly influence its biomechanical behaviour. However, the effects of these geometrical parameters are quite difficult to evaluate. An original numerical method is proposed in order to automatically generate parametric and subject-specif...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.04.007

    authors: Laville A,Laporte S,Skalli W

    更新日期:2009-07-22 00:00:00

  • Importance of preswing rectus femoris activity in stiff-knee gait.

    abstract::Stiff-knee gait is characterized by diminished and delayed knee flexion during swing. Rectus femoris transfer surgery, a common treatment for stiff-knee gait, is often recommended when a patient exhibits prolonged activity of the rectus femoris muscle during swing. Treatment outcomes are inconsistent, in part, due to ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2008.05.030

    authors: Reinbolt JA,Fox MD,Arnold AS,Ounpuu S,Delp SL

    更新日期:2008-08-07 00:00:00

  • A comparison of Coulomb and pseudo-Coulomb friction implementations: Application to the table contact phase of gymnastics vaulting.

    abstract::In the table contact phase of gymnastics vaulting both dynamic and static friction act. The purpose of this study was to develop a method of simulating Coulomb friction that incorporated both dynamic and static phases and to compare the results with those obtained using a pseudo-Coulomb implementation of friction when...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2011.07.022

    authors: Jackson MI,Hiley MJ,Yeadon MR

    更新日期:2011-10-13 00:00:00

  • A minimally disruptive technique for measuring intervertebral disc pressure in vitro: application to the cervical spine.

    abstract::A novel technique to measure in vitro disc pressures in human cervical spine specimens was developed. A miniature pressure transducer was used and an insertion technique was designed to minimise artefacts due to insertion. The technique was used to measure the intradiscal pressure in cervical spines loaded in pure axi...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(00)00205-0

    authors: Cripton PA,Dumas GA,Nolte LP

    更新日期:2001-04-01 00:00:00

  • Characterisation of vortex shedding in vascular anastomosis models using pulsed Doppler ultrasound.

    abstract::Vortex shedding at vascular anastomoses were investigated in vitro using a 20 MHz pulsed-wave Doppler velocimeter. Centreline velocity measurements were made at various axial distances in simplified polyurethane models of proximal and distal end-to-side anastomoses of angles 15, 30, 45, 60 and 80 degrees using pulsati...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00056-1

    authors: Gaupp S,Wang Y,How TV,Fish PJ

    更新日期:1999-07-01 00:00:00

  • On the importance of blood rheology for bulk flow in hemodynamic models of the carotid bifurcation.

    abstract::Here we present a study on the impact of assumptions on image-based hemodynamic simulations of healthy carotid bifurcations. In particular, we evaluate to which extent assumptions on blood rheology influence bulk flow features, driven by the fact that few studies have provided adequate insights into the influence of a...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2011.06.028

    authors: Morbiducci U,Gallo D,Massai D,Ponzini R,Deriu MA,Antiga L,Redaelli A,Montevecchi FM

    更新日期:2011-09-02 00:00:00

  • Hip endoprosthesis for in vivo measurement of joint force and temperature.

    abstract::Friction between the prosthetic head and acetabular cup increases the temperature in hip implants during activities like walking. A hip endoprosthesis was instrumented with sensors to measure the joint contact forces and the temperature distribution along the entire length of the titanium implant. Sensors and two indu...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00110-4

    authors: Graichen F,Bergmann G,Rohlmann A

    更新日期:1999-10-01 00:00:00

  • Digital volume correlation and micro-CT: An in-vitro technique for measuring full-field interface micromotion around polyethylene implants.

    abstract::Micromotion around implants is commonly measured using displacement-sensor techniques. Due to the limitations of these techniques, an alternative approach (DVC-μCT) using digital volume correlation (DVC) and micro-CT (μCT) was developed in this study. The validation consisted of evaluating DVC-μCT based micromotion ag...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.05.024

    authors: Sukjamsri C,Geraldes DM,Gregory T,Ahmed F,Hollis D,Schenk S,Amis A,Emery R,Hansen U

    更新日期:2015-09-18 00:00:00

  • Elastic area compressibility of the rabbit aorta.

    abstract::In this paper, we apply the micropipette to reduce the surface area of the rabbit aorta, and the relationship between the fractional area change of the aortic surface and the negative pressure in the pipette is studied. The experimental results for seven rabbit thoracic aortas show that the relationship can be express...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(96)00003-6

    authors: Yu Q,Wang X,Li G

    更新日期:1996-08-01 00:00:00

  • Effects of patella alta and patella infera on patellofemoral contact forces.

    abstract::The relationship between patella alta and patellar subluxation may, in part, reflect the relationship between the height of the patella above the tibiofemoral joint line and the patellofemoral contact force. This study reports on the direct in vitro measurement of the patellofemoral contact force, and its point of app...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(94)90222-4

    authors: Singerman R,Davy DT,Goldberg VM

    更新日期:1994-08-01 00:00:00

  • Musculo-articular modelling of the triceps brachii.

    abstract::With the aim of proposing modelling equations for the length, force and shortening velocity of the triceps brachii, an X-ray and biomechanical study was carried out on the elbow joint. Two series of three upper right limbs removed from cadavers were used. It allowed us to situate the articular rotational axis of the e...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(95)00032-1

    authors: Gerbeaux M,Turpin E,Lensel-Corbeil G

    更新日期:1996-02-01 00:00:00

  • Photogrammetric technique applied to anthropometric study of hands.

    abstract::Being concerned with physical anthropometric dimensions to explore avenues of research on hands and their working strategies, a research study was made to develop a suitable method by using available photogrammetric resources. The paper discusses the optimums of details found by this study, viz., the use of a Wild C-4...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(87)90039-x

    authors: Ghosh SK,Poirier F

    更新日期:1987-01-01 00:00:00

  • No consensus on causality of spine postures or physical exposure and low back pain: A systematic review of systematic reviews.

    abstract::Specific spinal postures and physical activities have been linked to low back pain (LBP) but previous reviews have produced contrasting outcomes. This umbrella review examined (1) what relationship, if any, is evident between specific spinal postures or physical activities and LBP; (2) the quality of existing systemat...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbiomech.2019.08.006

    authors: Swain CTV,Pan F,Owen PJ,Schmidt H,Belavy DL

    更新日期:2020-03-26 00:00:00

  • The effect of chemically defined medium on spontaneous calcium signaling of in situ chondrocytes during long-term culture.

    abstract::Chemically defined serum-free medium has been shown to better maintain the mechanical integrity of articular cartilage explants than serum-supplemented medium during long-term in vitro culture, but little is known about its effect on cellular mechanisms. We hypothesized that the chemically defined culture medium could...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.02.005

    authors: Zhou Y,Park M,Cheung E,Wang L,Lu XL

    更新日期:2015-04-13 00:00:00

  • Canine intersegmental hip joint forces and moments before and after cemented total hip replacement.

    abstract::Intersegmental forces and moments (i.e. resultant free body forces and moments computed at the joint centers) were studied in canine hindlimbs before and after cemented total hip replacement (THR). Five large, adult, mixed-breed dogs were selected. Their gait was recorded (while leash-walked) before surgery using high...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(91)90028-l

    authors: Dogan S,Manley PA,Vanderby R Jr,Kohles SS,Hartman LM,McBeath AA

    更新日期:1991-01-01 00:00:00

  • Effect of loss of balance on biomechanics platform measures of sway: influence of stance and a method for adjustment.

    abstract::This paper describes a method for adjusting biomechanics platform measures of sway for loss of balance. Area and velocity measures of sway were determined in forty-seven elderly women, in double and single leg stance, first with their eyes open, then closed. Subjects were rarely able to complete 10 s trials during sin...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(90)90025-x

    authors: Hasan SS,Lichtenstein MJ,Shiavi RG

    更新日期:1990-01-01 00:00:00

  • Why does intermittent hydrostatic pressure enhance the mineralization process in fetal cartilage?

    abstract::The purpose of this study was to determine which factor is the most likely one to have stimulated the mineralization process in the in vitro experiments of Klein-Nulend et al. (Arth. Rheum., 29, 1002-1009, 1986), in which fetal cartilaginous metatarsals were externally loaded with an intermittent hydrostatic pressure,...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(98)00165-1

    authors: Tanck E,van Driel WD,Hagen JW,Burger EH,Blankevoort L,Huiskes R

    更新日期:1999-02-01 00:00:00

  • A unified multiscale mechanical model for soft collagenous tissues with regular fiber arrangement.

    abstract::In this paper the mechanical response of soft collagenous tissues with regular fiber arrangement (RSCTs) is described by means of a nanoscale model and a two-step micro-macro homogenization technique. The non-linear collagen constitutive behavior is modeled at the nanoscale by a novel approach accounting for entropic ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.07.040

    authors: Maceri F,Marino M,Vairo G

    更新日期:2010-01-19 00:00:00

  • Determination of subject-specific model parameters for visco-elastic elements.

    abstract::The determination of subject-specific model parameter values is necessary in order for a computer simulation model of human motion to be evaluated quantitatively. This study used an optimisation procedure along with a kinematically driven simulation model of the contact phase in running jumps to determine the elastic ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2005.05.012

    authors: Wilson C,King MA,Yeadon MR

    更新日期:2006-01-01 00:00:00

  • The influence of the instabilities in modelling arteriovenous junction haemodynamics.

    abstract::The arteriovenous junction is characterised by high flow rates, large pressure difference and typically a palpable thrill or audible bruit, associated with turbulent flow. However, the arteriovenous junction is frequently studied with the assumption of streamline flow. This assumption is based on the Reynolds number c...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.07.038

    authors: Broderick SP,Houston JG,Walsh MT

    更新日期:2015-10-15 00:00:00

  • Statistical osteoporosis models using composite finite elements: a parameter study.

    abstract::Osteoporosis is a widely spread disease with severe consequences for patients and high costs for health care systems. The disease is characterised by a loss of bone mass which induces a loss of mechanical performance and structural integrity. It was found that transverse trabeculae are thinned and perforated while ver...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.06.017

    authors: Wolfram U,Schwen LO,Simon U,Rumpf M,Wilke HJ

    更新日期:2009-09-18 00:00:00

  • A first estimation of prestress in so-called circularly fibered osteonic lamellae.

    abstract::The existence and role of prestress in the various hierarchical structures of long bone are long standing questions. In this study, the prestress and associated strain that exist in a component of human bone microstructure, circularly fibered osteonic lamella, are estimated. Such estimates allow the formulation of hyp...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00080-9

    authors: Ascenzi MG

    更新日期:1999-09-01 00:00:00

  • Validation of a calibration technique for 6-DOF instrumented spatial linkages.

    abstract::This paper presents a practical and effective approach to the calibration of instrumented spatial linkages for biomechanical applications. A 6-DOF mechanical linkage with rotational transducers is designed and in-house manufactured for this purpose. In order to assess the validity of the proposed calibration technique...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2006.06.021

    authors: Gatti G,Danieli G

    更新日期:2007-01-01 00:00:00

  • Synthesis and characterisation of core-shell structures for orthopaedic surgery.

    abstract::This paperwork deals with the obtaining and characterisation of new acrylic cements for bone surgery. The final mixture of cement contains derivatives of methacryloyloxyethyl phosphate, methacrylic acid or 2-acrylamido-2-methyl-1-propane sulphonic acid. The idea of using these monomers is sustained by their ability to...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2007.05.002

    authors: Rusen E,Zaharia C,Zecheru T,Mărculescu B,Filmon R,Chappard D,Bădulescu R,Cincu C

    更新日期:2007-01-01 00:00:00

  • Differences between measured and resultant joint moments during isometric contractions at the ankle joint.

    abstract::The purpose of this study was to examine two hypotheses: (a) during voluntary and electrically induced isometric contractions the moments measured at the dynamometer are different from the resultant moments in the same plane around the ankle joint and (b) at a given resultant moment during electrically induced isometr...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2004.04.027

    authors: Arampatzis A,Morey-Klapsing G,Karamanidis K,DeMonte G,Stafilidis S,Brüggemann GP

    更新日期:2005-04-01 00:00:00

  • A telemetry-based device to determine the force-displacement behaviour of materials in high impact loading situations.

    abstract::Meaningful testing of stab resistant body armour requires the use of realistic body tissue simulants. A device for the determination of the force-displacement behaviour of materials in high impact loading situations has been developed for the testing of such simulants. Force measurement is achieved with the use of ele...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00191-8

    authors: Chadwick EK,Nicol AC,Floyd S,Gray TG

    更新日期:2000-03-01 00:00:00

  • Biomechanical influences of pin placement and elbow angle on hinge alignment and joint distraction of bridged elbow-pin-fixator construct.

    abstract::Joint distraction and mobilization with a hinged external fixator preserves elbow stability and mobility. However, the alignment of both elbow and fixator hinges was the initial prerequisite of the arthrodiatasis technique. The main goal of this study was to numerically evaluate the kinematic influence of the device, ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.07.030

    authors: Shih KS,Lin SC,Chao CK,Lee WS,Lu TW,Hou SM

    更新日期:2010-03-03 00:00:00

  • The range of axial rotation of the glenohumeral joint.

    abstract::There is a paucity of data in the literature on the restraining effects of the glenohumeral (GH) ligaments; cadaveric testing is one of the best methods for determining the function of these types of tissues. The aim of this work was to commission a custom-made six degrees of freedom (dof) joint loading apparatus and ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.03.007

    authors: Southgate DF,Hill AM,Alexander S,Wallace AL,Hansen UN,Bull AM

    更新日期:2009-06-19 00:00:00