Abstract：
:Considering that an athlete performs at-risk sports activities countless times throughout the course of his or her career prior to the instance of anterior cruciate ligament (ACL) injury, one may conclude that non-contact ACL injury is a rare event. Nevertheless, the overall number of non-contact ACL injuries, both in the US and worldwide, remains alarming due to the growing number of recreational and professional athletes participating in high-risk activities. To date, numerous non-contact ACL injury mechanisms have been proposed, but none provides a detailed picture of sequence of events leading to injury and the exact cause of this injury remains elusive. In this perspective article, we propose a new conception of non-contact ACL injury mechanism that comprehensively integrates risk factors inside and outside the knee joint. The proposed mechanism is robust in the sense that it is biomechanically justifiable and addresses a number of confounding issues related to ACL injury.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Hashemi J,Breighner R,Chandrashekar N,Hardy DM,Chaudhari AM,Shultz SJ,Slauterbeck JR,Beynnon BDdoi
10.1016/j.jbiomech.2010.11.013subject
Has Abstractpub_date
2011-02-24 00:00:00pages
577-85issue
4eissn
0021-9290issn
1873-2380pii
S0021-9290(10)00637-8journal_volume
44pub_type
杂志文章abstract：:The drop vertical jump (DVJ) task is commonly used to assess biomechanical performance measures that are associated with ACL injury risk in athletes. Previous investigations have solely assessed the first landing phase. We examined the first and second landings of a DVJ for differences in the magnitude of vertical gro...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2013.02.024
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abstract：:The determination of subject-specific model parameter values is necessary in order for a computer simulation model of human motion to be evaluated quantitatively. This study used an optimisation procedure along with a kinematically driven simulation model of the contact phase in running jumps to determine the elastic ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.05.012
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abstract：:The study verifies the development of active axial stress in the wall of mouse aorta over a range of physiological loads when the smooth muscle cells are stimulated to contract. The results obtained show that the active axial stress is virtually independent of the magnitude of pressure, but depends predominately on th...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2012.05.025
更新日期：2012-07-26 00:00:00
abstract：:We investigated the microstructural basis of a reduced stress concentration around the primary nutrient foramen of the equine third metacarpus. We quantified the spatial variations of compositional parameters (mineral content, volume fraction, histological architecture, and osteonal trajectories) from microradiographs...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(03)00130-1
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abstract：:The aim of this study was to test the hypothesis that running at fixed fractions of Froude (Nfr) and Strouhal (Str) dimensionless numbers combinations induce dynamic similarity between humans of different sizes. Nineteen subjects ran in three experimental conditions, (i) constant speed, (ii) similar speed (Nfr) and (i...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.10.012
更新日期：2014-12-18 00:00:00
abstract：:In this study, the effect of dehydration-hydration based sublamellar dimensional change on bone anisotropy was used as a tool to understand sublamellar organization of mineralized collagen fibrils. Bone consists of hydroxyapatite, Type I Collagen, mucopolysaccharides and bone fluid, which associates with bone constitu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109737
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abstract：:The purpose of this study was to investigate the mechanical consequences of proteoglycan 4 (Prg4) deficiency on intervertebral disc mechanics using a Prg4 knockout mouse model. Prg4, also called lubricin, was first identified as the boundary lubricant in synovial fluid but has subsequently been localized within a numb...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.03.029
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abstract：:The negative charges on proteoglycans significantly affect the mechanical behaviors of articular cartilage. Mixture theories, such as the triphasic theory, can describe quantitatively how this charged nature contributes to the mechano-electrochemical behaviors of such tissue. However, the mathematical complexity of th...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.10.026
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abstract：:The active control of the trunk plays an important role in frontal plane gait stability. We characterized trunk control in response to different step widths using a novel feedback system and examined the different effects of wide and narrow step widths as they each present unique task demands. Twenty healthy young adu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.110135
更新日期：2021-01-04 00:00:00
abstract：:Muscle compression commonly occurs in daily life (for instance wearing backpacks or compression garments, and during sitting). However, the effects of the compression on contraction dynamics in humans are not well examined. The aim of the study was to quantify the alterations of contraction dynamics and muscle archite...
journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2019-03-06 00:00:00
abstract：:Earlier experimental and finite element studies notwithstanding, the load transfer and stress distribution in the pelvic bone and the acetabulum in normal conditions are not well understood. This hampers the development of orthopaedic reconstruction methods. The present study deals with more precise finite element ana...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)00125-n
更新日期：1995-06-01 00:00:00
abstract：:Valgus moments on the knee joint during single-leg landing have been suggested as a risk factor for anterior cruciate ligament (ACL) injury. The purpose of this study was to test the influence of isolated valgus moment on ACL strain during single-leg landing. Physiologic levels of valgus moments from an in vivo study ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.10.031
更新日期：2009-02-09 00:00:00
abstract：:The damping mechanisms that are operational in the heel pad during the impact phase of locomotion have the important function to protect the musculo-skeletal system from injuries. How this is achieved is still not fully understood, as is for instance illustrated by the 'heel pad paradox', the observation that in vivo ...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2004.10.006
更新日期：2005-12-01 00:00:00
abstract：:Previous epidemiological studies indicate that the use of thumb-push mechanical pipettes is associated with musculoskeletal disorders (MSDs) in the hand. The goal of the current study was to analyze the loading in the muscle-tendon units in the thumb during pipetting. The hand is modeled as a multi-body linkage system...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2013.11.015
更新日期：2014-01-22 00:00:00
abstract：:Factors were examined which altered the propagation of aortic dissections in canine aortas. Thoracic aortas were removed from sacrificed dogs from the distal end of the arch to the diaphragm. An intimal tear was created at the proximal end of the aorta. The dissection was propagated using a pulsatile pressure system w...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(87)90268-5
更新日期：1987-01-01 00:00:00
abstract：:A simple axisymmetric finite element model of a human spine segment containing two adjacent vertebrae and the intervening intervertebral disc was constructed. The bodies and disc were modeled by three substructures; one to represent each of the vertebral bodies, the annulus fibrosus, and the nucleus pulposus. A semi-a...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(84)90128-3
更新日期：1984-01-01 00:00:00
abstract：:Patterns in cell adhesion molecule expression by endothelial cells may play a role in atherogenesis. Previous studies have shown dependence of intracellular adhesion molecule-1 (ICAM-1) expression in human umbilical vein endothelial cells (HUVEC) on shear stress and have indirectly linked ICAM-1 expression to spatial ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.02.002
更新日期：2006-01-01 00:00:00
abstract：:Significant ground reaction forces exceeding body weight occur during the heel-strike phase of gait. The standard methods of analytical dynamics used to solve the impact problem do not accommodate well the heel-strike collision due to the persistent contact at the front foot and presence of contact at the back foot. T...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(00)00006-3
更新日期：2000-06-01 00:00:00
abstract：:Lower limb amputation substantially disrupts motor and proprioceptive function. People with lower limb amputation experience considerable impairments in walking ability, including increased fall risk. Understanding the biomechanical aspects of the gait of these patients is crucial in improving their gait function and ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.02.033
更新日期：2014-05-07 00:00:00
abstract：:Aging brings about challenges in the ability to recover balance through protective stepping, especially in the lateral direction. Previous work has suggested that lateral protective stepping during weight transfer may be affected by impaired muscle composition and performance of the hip abductors (AB) in older adults....
journal_title：Journal of biomechanics
pub_type： 杂志文章
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abstract：:In the present study, the electro-mechanical properties of human knee articular cartilage were measured in vitro. An arthroscopic measurement tool was used to measure streaming potential integral (SPI), after which creep indentation tests were performed. Additionally, degradation level of the tissue was determined in ...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2013.02.004
更新日期：2013-04-26 00:00:00
abstract：:Although micromechanical finite-element models are being increasingly used to help interpret the results of bio-mechanical tests, there has not yet been a systematic study of the numerical errors and uncertainties that occur with these methods. In this work, finite-element models of human L1 vertebra have been used to...
journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：1998-10-01 00:00:00
abstract：:The purpose of this study was to employ subject-specific computer models to evaluate the interaction of glenohumeral range-of-motion and Hill-Sachs humeral head bone defect size on engagement and shoulder dislocation. We hypothesized that the rate of engagement would increase as defect size increased, and that greater...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.11.001
更新日期：2016-02-29 00:00:00
abstract：:Increasing diversity in the STEM (Science, Technology, Engineering, and Math) fields has become imperative to ensure equitable access to economic opportunity and to provide the technologically adept workforce of the future. The present STEM pipeline preferentially engages youth who are, not only aware of and intereste...
journal_title：Journal of biomechanics
pub_type： 杂志文章
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abstract：:Joint distraction and mobilization with a hinged external fixator preserves elbow stability and mobility. However, the alignment of both elbow and fixator hinges was the initial prerequisite of the arthrodiatasis technique. The main goal of this study was to numerically evaluate the kinematic influence of the device, ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.07.030
更新日期：2010-03-03 00:00:00
abstract：:Morphometrical and postural features of the cervical spine are supposed to significantly influence its biomechanical behaviour. However, the effects of these geometrical parameters are quite difficult to evaluate. An original numerical method is proposed in order to automatically generate parametric and subject-specif...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.04.007
更新日期：2009-07-22 00:00:00
abstract：:In this study, a three-dimensional finite element model was used to investigate the changes in tissue composition and mechanical signals within human lumbar intervertebral disc during the degenerative progression. This model was developed based on the cell-activity coupled mechano-electrochemical mixture theory. The d...
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pub_type： 杂志文章
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abstract：:Bone formation through matrix synthesis and calcification in response to mechanical loading is an essential process of the maturation in immature animals, although how mechanical loading applied to the tissue increases the calcification and improves mechanical properties, and which directions the calcification progres...
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abstract：:The mechanism of vertebral wedge fractures remains unclear and may relate to typical variations in the mechanical behavior of the intervertebral disc. To gain insight, we tested 16 individual whole discs (between levels T8 and L5) from nine cadavers (mean±SD: 66±16 years), loaded in compression at different rates (0.0...
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pub_type： 杂志文章
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更新日期：2016-05-03 00:00:00
abstract：:While measuring knee motion in all six degrees of freedom is important for understanding and treating orthopaedic knee pathologies, traditional motion capture techniques lack the required accuracy. A variety of model-based biplane fluoroscopy techniques have been developed with sub-millimeter accuracy. However, no stu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2012.08.045
更新日期：2012-11-15 00:00:00
