Abstract：
:In the present study, the electro-mechanical properties of human knee articular cartilage were measured in vitro. An arthroscopic measurement tool was used to measure streaming potential integral (SPI), after which creep indentation tests were performed. Additionally, degradation level of the tissue was determined in accordance with the International Cartilage Repair Society (ICRS score), and hematoxylin/eosin and safranin O staining were performed to determine the Mankin score. Mechanical test results were evaluated both analytically and by means of a finite-element-optimized parameter identification procedure. The SPI was then correlated with poroelastic E modulus (r=0.563, p<0.008, n=22), natural logarithm of hydraulic permeability (r=0.374, p<0.095, n=22) and cartilage degeneration scores (ICRS and Mankin) (r=-0.749, p<0.000, n=22 and r=-0.409, p<0.059, n=22 respectively).
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Abedian R,Willbold E,Becher C,Hurschler Cdoi
10.1016/j.jbiomech.2013.02.004subject
Has Abstractpub_date
2013-04-26 00:00:00pages
1328-34issue
7eissn
0021-9290issn
1873-2380pii
S0021-9290(13)00074-2journal_volume
46pub_type
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