Abstract：
:Stress and deformation in arterial wall tissue are factors which may influence significantly its response and evolution. In this work we develop models based on nonlinear elasticity and finite element numerical solutions for the mechanical behaviour and the remodelling of the soft tissue of arteries, including anisotropy induced by the presence of collagen fibres. Remodelling and growth in particular constitute important features in order to interpret stenosis and atherosclerosis. The main object of this work is to model accurately volumetric growth, induced by fluid shear stress in the intima and local wall stress in arteries with patient-specific geometry and loads. The model is implemented in a nonlinear finite element setting which may be applied to realistic 3D geometries obtained from in vivo measurements. The capabilities of this method are demonstrated in several examples. Firstly a stenotic process on an idealised geometry induced by a non-uniform shear stress distribution is considered. Following the growth of a right coronary artery from an in vivo reconstructed geometry is presented. Finally, experimental measurements for growth under hypertension for rat carotid arteries are modelled.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Rodríguez J,Goicolea JM,Gabaldón Fdoi
10.1016/j.jbiomech.2006.05.002subject
Has Abstractpub_date
2007-01-01 00:00:00pages
961-71issue
5eissn
0021-9290issn
1873-2380pii
S0021-9290(06)00153-9journal_volume
40pub_type
杂志文章abstract：:Falls due to slipping are a serious concern, with slipping estimated to cause 40-50% of all fall-related injuries. Epidemiological data indicates that older and obese adults experience more falls than young, non-obese individuals. An increasingly heavier and older U.S. population and workforce may be exacerbating the ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
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更新日期：2016-03-21 00:00:00
abstract：:Solids such as polymers, soft biological tissues display visco-hyperelastic, isochoric and finite deformation behaviour. The incompressibility constraint imposed severe restriction on the displacement field results in volumetric locking. Many techniques have been developed to address the issue such as reduced integrat...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.03.016
更新日期：2018-05-17 00:00:00
abstract：:Stem-cement and cement-bone interfacial failures as well as cement fractures have been noted in cemented total hip arthroplasty (THA) as the cause of aseptic loosening. Attempts to reduce the risk of femoral component loosening include improving the stem-cement interface by various coatings, using a textured or porous...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2012.12.010
更新日期：2013-03-15 00:00:00
abstract：:The measurement of relative motion between two moving bones is commonly accomplished for in vitro studies by attaching to each bone a series of either passive or active markers in a fixed orientation to create a rigid body (RB). This work determined the accuracy of motion between two RBs using an Optotrak optical moti...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2006.01.017
更新日期：2007-01-01 00:00:00
abstract：:The arteriovenous junction is characterised by high flow rates, large pressure difference and typically a palpable thrill or audible bruit, associated with turbulent flow. However, the arteriovenous junction is frequently studied with the assumption of streamline flow. This assumption is based on the Reynolds number c...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.07.038
更新日期：2015-10-15 00:00:00
abstract：:During range of motion (max-ROM) tests performed on an isokinetic dynamometer, the mechanical delay between the button press (by the participant to signal their max-ROM) and the stopping of joint rotation resulting from system inertia induces errors in both max-ROM and maximum passive joint moment. The present study a...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.05.036
更新日期：2019-07-19 00:00:00
abstract：:Little information is available on the direction-dependency of shear behavior in mandibular condylar cartilage. Therefore, we tested the hypothesis that such a dependency of the dynamic shear properties is present in mandibular condylar cartilage. From each of 17 condyles, two cartilage-bone plugs were dissected and t...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.12.012
更新日期：2008-01-01 00:00:00
abstract：:The geometry of a typical adult human carotid bifurcation, complete with the sinus, was established from a study of a large number of angiograms. A rigid model was constructed from glass and investigations were performed under steady flow conditions using flow visualization techniques over a range of upstream Reynolds...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(82)90057-4
更新日期：1982-01-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.09.006
更新日期：2016-04-11 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(98)00108-0
更新日期：1998-10-01 00:00:00
abstract：:A new approach for the assessment of gait patterns is presented. The use of neural network techniques for decision making in gait analysis is for some purposes more effective than biomechanical methods or conventional statistics. To demonstrate this, a neural network was trained to distinguish 'healthy' from 'patholog...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(93)90028-d
更新日期：1993-06-01 00:00:00
abstract：:As plaque develops in arteries two types of remodeling can occur; positive and negative remodeling. Positive remodeling is an outward compensatory remodeling in which the arterial wall grows outward in an attempt to maintain a constant lumen diameter, while negative remodeling is defined as a local shrinkage of vessel...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2013.02.012
更新日期：2013-04-26 00:00:00
abstract：:Mechanical environment in callus is determinant for the evolution of bone healing. However, recent mechanobiological computational works have underestimated the effect that growth exerts on the mechanical environment of callus. In the present work, we computationally evaluate the significance of growth-induced stresse...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.04.021
更新日期：2011-06-03 00:00:00
abstract：:As a support to the tooth, the mechanical response of the periodontal ligament (PDL) is complex. Like other connective tissues, the PDL exhibits non-linear and time-dependent behavior. The viscoelasticity of the PDL plays a significant role in low and high loading rates. Little information, however, is available on th...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.02.020
更新日期：2016-03-21 00:00:00
abstract：:To evaluate the efficacy of implanting a tilting disc aortic valve prosthesis in an angulated (wedged) supra-annular position, an in vitro experimental study was performed. The aortic valve prosthesis was mounted in an axi-symmetric valve chamber in a wedged position and incorporated in a mock circulatory system. Meas...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(86)90150-8
更新日期：1986-01-01 00:00:00
abstract：:Mechanical adaptions of cells, including stiffness variation, cytoskeleton remodeling, motion coordination, and shape changing, are essential for tissue morphogenesis, wound healing, and malignant progression. In this paper, we take confluent monolayers of Madin-Darby canine kidney (MDCK) and mouse myoblast (C2C12) ce...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109763
更新日期：2020-05-07 00:00:00
abstract：:Non-invasive estimation of arterial blood volume flow (BVF) has become a central issue in assessment of cardiovascular risk. Poiseuille and Womersley approaches are commonly used to assess the BVF from centerline velocity, but both methods neglect the influence of curvature. Based on the assumption that the velocity i...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.04.032
更新日期：2009-08-07 00:00:00
abstract：:The objective of our study was to evaluate the impact of a biphaseal anterior-posterior (AP) and internal-external (IE) motion restraint system on the wear behaviour, tibio-femoral kinematics and particle release of a mobile bearing posterior stabilised knee design in comparison to the widely used linear restraint. in...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.04.020
更新日期：2014-07-18 00:00:00
abstract：:Although the capacity of bone to adapt to functional mechanical requirements has been known for more than a century, it is still unclear how the bone adaptation processes are regulated. We hypothesize that osteocytes are sensitive to mechanical loading and control the regulation of bone mass in their environment. Rece...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)90049-3
更新日期：1994-11-01 00:00:00
abstract：:The reliability of joint rotation measurements is an issue of major interest, especially in clinical applications. The effect of instrumental errors and soft tissue artifacts on the variability of human motion measures is well known, but the influence of the representation of joint motion has not yet been studied. The...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.12.045
更新日期：2016-02-08 00:00:00
abstract：:Experimental evidence demonstrates that collagen cross-linking in bone tissue significantly influences its deformation and failure behavior yet difficulties exist in determining the independent biomechanical effects of collagen cross-linking using in vitro and in vivo experiments. The aim of this study is to use a nan...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.02.017
更新日期：2008-01-01 00:00:00
abstract：:Intramuscular pressure correlates strongly with muscle tension and is a promising tool for quantifying individual muscle force. However, clinical application is impeded by measurement variability that is not fully understood. Previous studies point to regional differences in IMP, specifically increasing pressure with ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.09.002
更新日期：2016-10-03 00:00:00
abstract：:Predicting subject-specific responses to exoskeleton assistance may aid in maximizing functional gait outcomes, such as achieving full knee-extension at foot contact in individuals with crouch gait from cerebral palsy (CP). The purpose of this study was to investigate the role of volitional and non-volitional muscle a...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.02.025
更新日期：2019-04-18 00:00:00
abstract：:Two questions were addressed in this study: (1) how much strain of the superficial aponeurosis of the human medial gastrocnemius muscle (MG) was obtained during voluntary isometric contractions in vivo, (2) whether there existed inhomogeneity of the strain along the superficial aponeurosis. Seven male subjects, whose ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(01)00196-8
更新日期：2002-02-01 00:00:00
abstract：:Relatively high rates of loosening and implant failure have been reported after total ankle arthroplasty. Abnormal kinematics and incongruency of the articular surface may cause increased contact pressure and rotational torque applied to the implant, leading to loosening and implant failure. We measured in vivo kinema...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2012.05.043
更新日期：2012-08-09 00:00:00
abstract：:The gait cycle is usually analyzed using one of two conventions: heel contact initiates the cycle and stance is followed by swing phases or toe-off initiates the cycle and swing then stance phases are analyzed. The purpose of the study is to demonstrate that based on a consideration of relevant biomechanical measures,...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)90025-6
更新日期：1994-04-01 00:00:00
abstract：:The relationship between patella alta and patellar subluxation may, in part, reflect the relationship between the height of the patella above the tibiofemoral joint line and the patellofemoral contact force. This study reports on the direct in vitro measurement of the patellofemoral contact force, and its point of app...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)90222-4
更新日期：1994-08-01 00:00:00
abstract：:Cellular mechanics is known to play an important role in many cellular functions including adhesion, migration, proliferation, and differentiation. Human mesenchymal stem cells (hMSCs) demonstrate unique mechanical properties distinct from fully differentiated cells. This observation suggests that the stem cell mechan...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.07.024
更新日期：2011-10-13 00:00:00
abstract：:The periodontal ligament (PDL) is a critical player in the maintenance of tooth health, acting as the primary stabilizer of tooth position. Recent studies have identified two unique regions within the PDL, the 'dense collar' region and the 'furcation' region, which exhibit distinct structural and compositional differe...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109996
更新日期：2020-10-09 00:00:00
abstract：OBJECTIVE:This paper documents research that quantifies and describes the biomechanics of normal gait on inclined surfaces. DESIGN:Experimental, investigative. BACKGROUND:It is necessary to walk on inclined surfaces to negotiate the natural and built environments. Little research has been conducted on the biomechanic...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.07.025
更新日期：2006-01-01 00:00:00
