Abstract：
:Mechanical environment in callus is determinant for the evolution of bone healing. However, recent mechanobiological computational works have underestimated the effect that growth exerts on the mechanical environment of callus. In the present work, we computationally evaluate the significance of growth-induced stresses, commonly called residual stresses, in callus. We construct a mechanobiological model of a callus in the metatarsus of a sheep in two different stages: one week and four weeks after fracture. The magnitude of stresses generated during callus growth is compared with the magnitude of stresses when only external loads are applied to the callus. We predict that residual stresses are relevant in some areas, mainly located at the periosteal side far from the fracture gap. Therefore, the inclusion of these residual stresses could represent a significant impact on the callus growth and predict a different evolution of biological processes occurring during bone healing.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
González-Torres LA,Gómez-Benito MJ,García-Aznar JMdoi
10.1016/j.jbiomech.2011.04.021subject
Has Abstractpub_date
2011-06-03 00:00:00pages
1782-7issue
9eissn
0021-9290issn
1873-2380pii
S0021-9290(11)00341-1journal_volume
44pub_type
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