Abstract：
:Arterial embolism is responsible for the death of lots of people who suffers from heart diseases. The major risk of embolism in upper limbs is that the ruptured particles are brought into the brain, thus stimulating neurological symptoms or causing the stroke. We presented a computational model using fluid-structure interactions (FSI) to investigate the physical motion of a blood clot inside the human common carotid artery. We simulated transportation of a buoyant embolus in an unsteady flow within a finite length tube having stenosis. Effects of stenosis severity and embolus size on arterial hemodynamics were investigated. To fulfill realistic nonlinear property of a blood clot, a rubber/foam model was used. The arbitrary Lagrangian-Eulerian formulation (ALE) and adaptive mesh method were used inside fluid domain to capture the large structural interfacial movements. The problem was solved by simultaneous solution of the fluid and the structure equations. Stress distribution and deformation of the clot were analyzed and hence, the regions of the embolus prone to lysis were localized. The maximum magnitude of arterial wall shear stress during embolism occurred at a short distance proximal to the throat of the stenosis. Through embolism, arterial maximum wall shear stress is more sensitive to stenosis severity than the embolus size whereas role of embolus size is more significant than the effect of stenosis severity on spatial and temporal gradients of wall shear stress downstream of the stenosis and on probability of clot lysis due to clot stresses while passing through the stenosis.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Vahidi B,Fatouraee Ndoi
10.1016/j.jbiomech.2012.01.020subject
Has Abstractpub_date
2012-04-30 00:00:00pages
1312-22issue
7eissn
0021-9290issn
1873-2380pii
S0021-9290(12)00062-0journal_volume
45pub_type
杂志文章abstract：:Locomotion involves complex neural networks responsible for automatic and volitional actions. During locomotion, motor strategies can rapidly compensate for any obstruction or perturbation that could interfere with forward progression. In this pilot study, we examined the contribution of interlimb pathways for evoking...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.04.042
更新日期：2015-08-20 00:00:00
abstract：:The purpose of this study was to analyze the reproducibility of kinematic, dynamometric and derived mechanical energy parameters in the pole vault as a main precondition for the practical applicability of the concept of energy exchange in the pole vault. A total of 46 vaults of six experienced vaulters were analyzed. ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.03.027
更新日期：2006-01-01 00:00:00
abstract：:A technique is introduced for simultaneous measurements of the heel pad tissue deformation and the heel-ground contact stresses developing during the stance phase of gait. Subjects walked upon a gait platform integrating the contact pressure display optical method for plantar pressure measurements and a digital radiog...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(01)00143-9
更新日期：2001-12-01 00:00:00
abstract：:A method is presented for quantitative determination of skin movement over the underlying skeletal structures during normal locomotion of the horse. The principle of the method is simultaneous visualization of the position of the skin and the underlying bony structures, by marking the bones with implanted light-emitti...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(86)90138-7
更新日期：1986-01-01 00:00:00
abstract：:In this study, we tested the compressive stress relaxation behaviors of the mandibular condylar and temporal cartilages in the porcine temporomandibular joint (TMJ). The aim was to determine the quantitative and qualitative similarities and differences of compressive stress relaxation behaviors between the two cartila...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.03.007
更新日期：2014-05-07 00:00:00
abstract：:Poisson's ratio has not been experimentally measured earlier for meniscus in compression. It is however an important intrinsic material property needed in biomechanical analysis and computational models. In this study, equilibrium Poisson's ratio of bovine meniscus (n = 6) was determined experimentally by combining st...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.07.001
更新日期：2018-08-22 00:00:00
abstract：:Several studies have investigated the transmission of vibration from the vibrating plate of a whole-body vibration training machine (WBVTM) to different locations on the human body. No known work has investigated the interface force between the vibrating plate of the machine and the human body. This paper investigates...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.11.003
更新日期：2019-01-03 00:00:00
abstract：:Although arterio-venous grafts (AVGs) represent the second choice as permanent vascular access for hemodialysis, this solution is still affected by a relevant failure rate due to graft thrombosis, and development of neointimal hyperplasia (IH) at the distal vein. As a key role in these processes has been attributed to...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.109591
更新日期：2020-02-13 00:00:00
abstract：:The effect of dissipative mechanical loads on spastic gait has been studied, to evaluate the feasibility of using mechanically damped orthoses to effect functional improvements in the gait of spastic patients. This concept is based on a hypothesis citing uninhibited, velocity-dependent stretch reflexes as a possible c...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(85)90278-7
更新日期：1985-01-01 00:00:00
abstract：:Bending and compressive loads were applied intermittently at 0.5 Hz through implants chronically inserted into the radius and ulna of experimental sheep. The plane of bending was the same as that imposed during locomotion. The principal variables of the artificial strain regime were the peak strains and strain rates, ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(82)90092-6
更新日期：1982-01-01 00:00:00
abstract：:Traumatic damage to the brainstem occurs frequently when the brain skull complex experiences injurious loading especially during those traumatic situations that produce diffuse axonal injury (DAI). DAI has been shown to be dependent on load direction and correlated with regional tissue deformation in response to rotat...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(98)00068-2
更新日期：1998-09-01 00:00:00
abstract：:Range of motion (ROM) of the thoracic spine has implications in patient discrimination for diagnostic purposes and in biomechanical models for predictions of spinal loads. Few previous studies have reported quite different thoracic ROMs. Total (T1-T12), lower (T5-T12) and upper (T1-T5) thoracic, lumbar (T12-S1), pelvi...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.09.003
更新日期：2016-04-11 00:00:00
abstract：:Hamstring muscle strain injury is one of the most commonly seen injuries in sports such as track and field, soccer, football, and rugby. The purpose of this study was to advance our understanding of the mechanisms of hamstring muscle strain injuries during over ground sprinting by investigating hamstring muscle-tendon...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.09.005
更新日期：2008-11-14 00:00:00
abstract：:The finite element method described in this study provides an easy method to simulate the kinetics of multibody mechanisms. It is used in order to develop a musculoskeletal model of the shoulder mechanism. Each relevant morphological structure has been represented by an appropriate element. For the shoulder mechanism ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)90065-5
更新日期：1994-05-01 00:00:00
abstract：:Identification of kinetic variables in different masks of foot is important for the evaluation and treatment of chronic low back pain. The aim of this study was to investigate the effect of chronic idiopathic low back pain on kinetic variables of gait in different foot masks. 11 idiopathic chronic low back pain patien...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.08.013
更新日期：2018-10-05 00:00:00
abstract：:To know the contributions of blood pressure induced stress to the progression of atherosclerosis and the rupture of atheroma, cross-sectional distributions of stresses in atherosclerotic walls were calculated by finite element method, using stress-strain data of aortic walls and atherosclerotic plaques obtained from h...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(96)00185-6
更新日期：1997-06-01 00:00:00
abstract：:The mechanical energy expenditures (MEEs) of two human lower extremity models with different sources of mechanical energy - (1) muscles and (2) joint moments - were compared theoretically. Sources of mechanical energy producing movement of Model 1 were eight muscle, three of which were two-joint muscles. Sources of me...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(95)00083-6
更新日期：1996-04-01 00:00:00
abstract：:Tendon elasticity is important for economical locomotion; however it is unknown whether tendon stiffness is appropriate to achieve an optimal efficiency in various muscles. Here we test the hypothesis that the Achilles tendon is of an appropriate stiffness to maximise medial gastrocnemius muscle efficiency during loco...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2006.07.025
更新日期：2007-01-01 00:00:00
abstract：:The purpose of this study was to apply the Floating Axis analysis technique to the elbow joint, and to verify its ability to quantify clinically relevant radiohumeral translation in vitro using an electromagnetic tracking device. Of particular interest was the ability to quantify changes in anterior-posterior radial h...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(03)00103-9
更新日期：2003-08-01 00:00:00
abstract：:Cross-linked polyethylene foam (Plastazote) has been used in the management of painful foot disorders occurring in a number of disease processes. A series of mechanical tests have been performed under varying clinically encountered conditions to show a relationship between the deformation of the material and the load ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(84)90101-5
更新日期：1984-01-01 00:00:00
abstract：:Gait analysis is a quantitative, non-invasive technique that can be used to investigate functional changes in animal models of musculoskeletal disease. Changes in ground reaction forces following injury have been observed that coincide with differences in tissue mechanical and histological properties during healing. H...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.12.027
更新日期：2016-02-08 00:00:00
abstract：:The surface roughness of a bone implant was defined parametrically. The values of the parameters defining the surface were varied. Some traditionally used surface roughness parameters were calculated. By means of a theoretical model the bone-implant interfacial shear strength was estimated. No simple correlation betwe...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(00)00045-2
更新日期：2000-10-01 00:00:00
abstract：:We assessed the local distribution of bone mechanical properties on a micro-nano-scale and its correlation to strain distribution. Left tibia samples were obtained from 5-month old female Sprague Dawley rats, including baseline control (n=9) and hindlimb suspended (n=9) groups. Elastic modulus was measured by nanoinde...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.11.052
更新日期：2016-01-25 00:00:00
abstract：:Electromagnetic tracking devices are used in many biomechanics applications. Previous studies have shown that metal located within the working field of direct current electromagnetic tracking devices produces significant errors. However, the effect of sampling rate on the errors produced in a metallic environment has ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(02)00322-6
更新日期：2003-01-01 00:00:00
abstract：:In inverse dynamics computations, the accuracy of the solution strongly depends on the accuracy of the input data. In particular, estimated joint moments are highly sensitive to uncertainties in acceleration data. The aim of the present work was to improve classical inverse dynamics computations by providing an accura...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(02)00176-8
更新日期：2002-11-01 00:00:00
abstract：:The successful development of early-stage cartilage and meniscus repair interventions in the knee requires biomechanical and biotribological understanding of the design of the therapeutic interventions and their tribological function in the natural joint. The aim of this study was to develop and validate a porcine kne...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.07.043
更新日期：2015-09-18 00:00:00
abstract：:This paper describes a method for adjusting biomechanics platform measures of sway for loss of balance. Area and velocity measures of sway were determined in forty-seven elderly women, in double and single leg stance, first with their eyes open, then closed. Subjects were rarely able to complete 10 s trials during sin...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(90)90025-x
更新日期：1990-01-01 00:00:00
abstract：:Nowadays in various daily, occupational and training activities, there are many occasions with forces supported in hands acting at various magnitudes, elevations, and orientations with substantial horizontal components. In this work, we aim to compute trunk muscle forces, stability, and spinal loads under pulling exte...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.09.036
更新日期：2016-04-11 00:00:00
abstract：:Several algorithms have been proposed for determining the centre of rotation of ball joints. These algorithms are used rather to locate the hip joint centre. Few studies have focused on the determination of the glenohumeral joint centre. However, no studies have assessed the accuracy and repeatability of functional me...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.09.029
更新日期：2010-01-19 00:00:00
abstract：:In this paper the mechanical response of soft collagenous tissues with regular fiber arrangement (RSCTs) is described by means of a nanoscale model and a two-step micro-macro homogenization technique. The non-linear collagen constitutive behavior is modeled at the nanoscale by a novel approach accounting for entropic ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.07.040
更新日期：2010-01-19 00:00:00
