Abstract：
:The geometry of a typical adult human carotid bifurcation, complete with the sinus, was established from a study of a large number of angiograms. A rigid model was constructed from glass and investigations were performed under steady flow conditions using flow visualization techniques over a range of upstream Reynolds numbers and flow division ratios through the branches representative of physiologic conditions expected in the human vasculature. The study reveals a complex flow field in which secondary flows play an important role. The separation regions occurring at the outer corners of the branching are also subjected to much higher shear stress. Comparison with pathologic data on localization of atherosclerotic lesions indicates that zones susceptible to disease experience low or oscillatory shear stress while regions subject to higher shear are free of deposits.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Bharadvaj BK,Mabon RF,Giddens DPdoi
10.1016/0021-9290(82)90057-4subject
Has Abstractpub_date
1982-01-01 00:00:00pages
349-62issue
5eissn
0021-9290issn
1873-2380pii
0021-9290(82)90057-4journal_volume
15pub_type
杂志文章abstract：:As humans walk or run, external (environmental) and internal (physiological) disturbances induce variability. How humans regulate this variability from stride-to-stride can be critical to maintaining balance. One cannot infer what is "controlled" based on analyses of variability alone. Assessing control requires quant...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.05.034
更新日期：2018-07-25 00:00:00
abstract：:The reverse shoulder prosthesis aims to restore the stability and function of pathological shoulders, but the biomechanical aspects of the geometrical changes induced by the implant are yet to be fully understood. Considering a large-scale musculoskeletal model of the upper limb, the aim of this study is to evaluate h...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.06.031
更新日期：2015-09-18 00:00:00
abstract：:Consistent measurement of maximum running speed overground is problematic due to the difficulty in precise, continual measurement of speed, and the substantial workload in accelerating the body promoting the onset of fatigue. Treadmills remove the requirement for acceleration which enables more repeats. They also allo...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.07.024
更新日期：2009-11-13 00:00:00
abstract：:The majority of fall-related accidents are during stair ambulation-occurring commonly at the top and bottom stairs of each flight, locations in which individuals are transitioning to stairs. Little is known about how individuals adjust their biomechanics in anticipation of walking-stair transitions. We identified the ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.12.041
更新日期：2016-02-29 00:00:00
abstract：:The purpose of the present study was to investigate the effects of mechanical strain, anisotropy, and tissue region on electrical conductivity and ion diffusivity in meniscus fibrocartilage. A one-dimensional, 4-wire conductivity experiment was employed to measure the electrical conductivity in porcine meniscus tissue...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.06.011
更新日期：2016-09-06 00:00:00
abstract：:The biomechanical environment of the optic nerve head (ONH), of interest in glaucoma, is strongly affected by the biomechanical properties of sclera. However, there is a paucity of information about the variation of scleral mechanical properties within eyes and between individuals. We thus used biaxial testing to meas...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.02.031
更新日期：2010-06-18 00:00:00
abstract：:The accumulation of a fluid property from the standpoint of a particle moving with non-steady fluid flow (i.e., platelet/blood-cell damage index in pulsating blood flow) is a challenged computational problem due to the current need for particle-tracing methods. The method we developed (dubbed VPI) enables the approxim...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.11.011
更新日期：2010-03-22 00:00:00
abstract：:Kinesin is a microtubule-based motor protein that generates motion involved in intracellular trafficking and cell division. Even if the force-generating and enzymatic properties of kinesin were extensively studied, the molecular basis of its interaction with the microtubule is still not well understood. The aim of the...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.08.014
更新日期：2008-11-14 00:00:00
abstract：:In this work we propose a method to estimate the elastic properties of the extracellular matrix of articular cartilage, once the elastic properties of the chondrocytes and the whole tissue are known. The influence of the elastic properties of the tissue and the cell concentration on the estimated elastic properties of...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(03)00280-x
更新日期：2004-03-01 00:00:00
abstract：:The take-off phase (approximately 6m) of the jumps of all athletes participating in the individual HS-106m hill ski jumping competition at the Torino Olympics was filmed with two high-speed cameras. The high altitude of the Pragelato ski jumping venue (1600m) and slight tail wind in the final jumping round were expect...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.02.026
更新日期：2009-05-29 00:00:00
abstract：:The influence of ankle kinematics and plantar pressure from mid-range barefoot running on T2 relaxation times of tibiotalar cartilage is unknown. This study aimed to quantitatively evaluate the T2 relaxation time of tibiotalar cartilage and ankle biomechanics following 5 km barefoot running. Twenty healthy runners (wh...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.04.046
更新日期：2019-06-11 00:00:00
abstract：:Many clinical studies suggest that local blood flow patterns are involved in the location and development of atherosclerosis. In coronary diseases, this assumption should be corroborated by quantitative information on local hemodynamic parameters such as pressure, velocity or wall shear stress. Nowadays, computational...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(02)00179-3
更新日期：2002-10-01 00:00:00
abstract：:Mechanical adaptions of cells, including stiffness variation, cytoskeleton remodeling, motion coordination, and shape changing, are essential for tissue morphogenesis, wound healing, and malignant progression. In this paper, we take confluent monolayers of Madin-Darby canine kidney (MDCK) and mouse myoblast (C2C12) ce...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109763
更新日期：2020-05-07 00:00:00
abstract：:2D, coronal plane, finite elements models (FEMs) were developed from orthogonal radiographs of a diaphyseal tibial fracture and its reparative tissue at four different time points during healing. Each callus was separated into regions of common tissue histology by computerised radiographic analysis. Starting point val...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00189-x
更新日期：2000-04-01 00:00:00
abstract：:Perturbed aorta hemodynamics, as for the carotid and the coronary artery, has been identified as potential predicting factor for cardiovascular diseases. In this study, we propose a parametric study based on the computational fluid dynamics with the aim of providing information regarding aortic disease. In particular,...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109691
更新日期：2020-04-16 00:00:00
abstract：:Dynamic balance in the frontal plane requires active control, which is accomplished largely through control of mediolateral foot placement. Individuals without mobility impairments have the ability to compensate for variability in foot-placement to maintain their balance; however, it is unknown how individuals respond...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.110213
更新日期：2020-12-28 00:00:00
abstract：:The structure and function of the renal artery ostium flow diverter on the caudal side of the renal branch point were previously reported; in this study, we further evaluate the diverter׳s possible functions. The protrusion of this structure into the abdominal aorta suggests that the diverter may preferentially direct...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.03.006
更新日期：2014-05-07 00:00:00
abstract：:Risk for injury during a fall depends on the position and velocity of the body segments at the moment of impact. One technique for reducing impact velocity is to absorb energy in the lower extremity muscles during descent, as occurs during squatting or sitting. However, the protective value of this response may depend...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2003.12.015
更新日期：2004-09-01 00:00:00
abstract：:The negative charges on proteoglycans significantly affect the mechanical behaviors of articular cartilage. Mixture theories, such as the triphasic theory, can describe quantitatively how this charged nature contributes to the mechano-electrochemical behaviors of such tissue. However, the mathematical complexity of th...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.10.026
更新日期：2010-03-03 00:00:00
abstract：:Biomechanical models may aid in improving diagnosis and treatment of wrist joint disorders. As input, geometrical information is required for model development. Previous studies acquired some elements of the average wrist joint geometry. However, there is a close geometric functional match between articulating surface...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.11.003
更新日期：2010-03-22 00:00:00
abstract：:Transcatheter aortic valve replacement (TAVR) is an established treatment alternative to surgical valve replacement in high-risk patients with severe symptomatic aortic stenosis. The current guidelines for TAVR are to upsize transcatheter aortic valve (TAV) relative to the native annulus to secure the device and minim...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.08.012
更新日期：2015-10-15 00:00:00
abstract：:Twelve seated male subjects were exposed to 15 vibration conditions to investigate the nature and mechanisms of the non-linearity in biomechanical response. Subjects were exposed to three groups of stimuli: Group A comprised three repeats of random vertical vibration at 0.5, 1.0 and 1.5 ms(-2) r.m.s. with subjects sit...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.09.024
更新日期：2006-01-01 00:00:00
abstract：:Considerable forces and moments act at hip prostheses during most kinds of physical activities. High torque around the stem axis may contribute to implant loosening. With instrumented hip prostheses the joint force and its direction, the bending moment in the frontal plane and the torque were measured in two patients ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)00105-d
更新日期：1995-05-01 00:00:00
abstract：:A new six-degree-of-freedom force transducer has been manufactured, with the sensitivity to measure forces in the range +/-100 N and moments of up to +/-5 Nm. The transducer incorporates two mechanical components: shear forces and bending moments are measured via a strain-gauged tubular section whilst axial forces are...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00054-8
更新日期：1999-07-01 00:00:00
abstract：:The purpose of the current investigation was to use finite element analysis to quantify the complete strain field for the membranes of the Flexercell apparatus, a device extensively used to study the effects of mechanical loading on cultured cells. Four vacuum pressure simulations were run for the membrane for both th...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2004.02.022
更新日期：2004-12-01 00:00:00
abstract：:The performance criterion in maximum vertical jumping has typically been assumed to simply raise the center of mass as high as possible. In many sporting activities minimizing movement time during the jump is likely also critical to successful performance. The purpose of this study was to examine maximum height jumps ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.04.021
更新日期：2015-08-20 00:00:00
abstract：:Fall prevention has an indispensable role in enhancing life expectancy and quality of life among older adults. The first step to prevent falls is to devise reliable methods to identify individuals at high fall risk. The purpose of the current study was to assess alterations in local postural muscle and central sensory...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2018.01.027
更新日期：2018-04-11 00:00:00
abstract：:A two-dimensional, five-muscle model was used to determine the degree of precision required for accurate calculation of temporomandibular joint force magnitude and direction. The sensitivity of the calculations to each variable were assessed by incrementing each variable through its presumed biological range and were ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(89)90206-6
更新日期：1989-01-01 00:00:00
abstract：:Sudden heart attacks remain one of the primary causes of premature death in the developed world. Asymptomatic vulnerable plaques that rupture are believed to prompt such fatal heart attacks and strokes. The role of microcalcifications in the vulnerable plaque rupture mechanics is still debated. Recent studies suggest ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.11.029
更新日期：2008-01-01 00:00:00
abstract：:Bone fracture reduction and bone axial dynamization are important operations which effectiveness can be further enhanced by the use of a unilateral external fixator. By design, axial dynamization can be performed through reciprocating one of its translational joints. However, non-axial dynamization may occur after cor...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.05.002
更新日期：2009-08-25 00:00:00
