Effect of substance P on somatostatin release from the isolated perfused rat stomach.

abstract：BACKGROUND & AIMS:Carcinomas of the extrahepatic bile ducts, ampulla of Vater, and duodenum are uncommon, and their epigenetic and genetic alterations are not well characterized. METHODS:We therefore compared the methylation profile and genetic alterations in 18 extrahepatic biliary, 9 ampullary, and 12 duodenal carci...

journal_title：Gastroenterology

authors： Kim SG,Chan AO,Wu TT,Issa JP,Hamilton SR,Rashid A

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND & AIMS:We performed a prospective, randomized, controlled study to compare the combination of esomeprazole and clopidogrel vs clopidogrel alone in preventing recurrent peptic ulcers in patients with atherosclerosis and a history of peptic ulcers. We also investigated the effects of esomeprazole on the antipl...

journal_title：Gastroenterology

authors： Hsu PI,Lai KH,Liu CP

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND & AIMS:Pancreatitis starts with primarily sterile local inflammation that induces systemic inflammatory response syndrome, followed by compensatory anti-inflammatory response syndrome (CARS). We investigated the mechanisms of these processes in mice and human serum. METHODS:We induced severe acute pancreati...

journal_title：Gastroenterology

authors： Sendler M,van den Brandt C,Glaubitz J,Wilden A,Golchert J,Weiss FU,Homuth G,De Freitas Chama LL,Mishra N,Mahajan UM,Bossaller L,Völker U,Bröker BM,Mayerle J,Lerch MM

更新日期：2020-01-01 00:00:00

abstract：:A randomized, controlled trial was conducted to investigate the ability of indomethacin and chloroquine to reduce intestinal secretion in 29 adult patients with severe cholera. All patients received intravenous infusion to restore fluid balance, but no antibiotics were given. Patients treated with oral indomethacin (t...

journal_title：Gastroenterology

authors： Rabbani GH,Butler T

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND & AIMS:The role of the gallbladder in gallstone pathogenesis is still unclear. We examined the effects of gallbladder mucosal lipid absorption on lipid composition and cholesterol crystallization in bile. METHODS:The in vitro-isolated, intra-arterially perfused gallbladder model was used (1) to compare the ...

journal_title：Gastroenterology

authors： Corradini SG,Elisei W,Giovannelli L,Ripani C,Della Guardia P,Corsi A,Cantafora A,Capocaccia L,Ziparo V,Stipa V,Chirletti P,Caronna R,Lomanto D,Attili AF

更新日期：2000-05-01 00:00:00

abstract：:Intestinal mucosal biopsy immunoglobulin content in a patient with eosinophilia, allergic gastroenteropathy (atopy, food sensitivities, protein-losing enteropathy, iron deficiency anemia, and growth retardation), and hyperimmunoglobulinemia E (68,000 units) was compared with that of a control group and a group with eo...

journal_title：Gastroenterology

authors： Caldwell JH,Sharma HM,Hurtubise PE,Colwell DL

更新日期：1979-09-01 00:00:00

abstract：:A 62-year-old man with rheumatoid arthritis developed jaundice while taking piroxicam. A full evaluation including ultrasound, computerized tomography, endoscopic cholangiography, and liver biopsy confirmed the diagnosis of intrahepatic cholestasis. The patient's jaundice and all other liver function abnormalities nor...

journal_title：Gastroenterology

authors： Hepps KS,Maliha GM,Estrada R,Goodgame RW

更新日期：1991-12-01 00:00:00

abstract：:Development of an intraabdominal bile collection (biloma) usually occurs secondary to traumatic or iatrogenic injury including abdominal surgery, percutaneous catheter drainage, and transhepatic cholangiogram. We present a case of hepatic subcapsular biloma following endoscopic retrograde cholangiography and identifie...

journal_title：Gastroenterology

authors： Dupas JL,Mancheron H,Sevenet F,Delamarre J,Delcenserie R,Capron JP

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND & AIMS:Although calcium plays an essential role in intestinal smooth muscle contractile activity, calcium entry pathways in canine and human small intestine are largely unknown. The goal of this study was to characterize calcium channels, a potential entry pathway for calcium, in isolated circular smooth mus...

journal_title：Gastroenterology

authors： Farrugia G,Rich A,Rae JL,Sarr MG,Szurszewski JH

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Mutations in HFE are the most common cause of the iron-overload disorder hereditary hemochromatosis. Levels of the main iron regulatory hormone, hepcidin, are inappropriately low in hereditary hemochromatosis mouse models and patients with HFE mutations, indicating that HFE regulates hepcidin. The b...

journal_title：Gastroenterology

authors： Corradini E,Garuti C,Montosi G,Ventura P,Andriopoulos B Jr,Lin HY,Pietrangelo A,Babitt JL

更新日期：2009-10-01 00:00:00

abstract：:To determine the amount of lactose that could be tolerated in a meal, 59 lactase-deficient American Indians, ranging in age from 5 to 62, were given graded doses of lactose. The diagnosis of lactase deficiency had beeen documented previously by showing increased breath hydrogen after an oral lactose load (2 g per kg, ...

journal_title：Gastroenterology

authors： Newcomer AD,McGill DB,Thomas PJ,Hofmann AF

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Serrated polyp (SPs) are precursors to 20% to 30% of cases of colorectal tumors, but patients' long-term risk after removal of SPs is poorly understood. We investigated the risk of colorectal cancer (CRC) in individuals with a history of SPs. METHODS:We performed a retrospective cohort study of Kai...

journal_title：Gastroenterology

authors： Li D,Liu L,Fevrier HB,Alexeeff SE,Doherty AR,Raju M,Amsden LB,Lee JK,Levin TR,Corley DA,Herrinton LJ

更新日期：2020-08-01 00:00:00

abstract：:Characteristics of a macroamylase that was considered not to be formed by the binding of normal amylase to immunoglobulins were studied. The macroamylase was reversibly dissociated into apparently normal amylase by treating the macroamylasemic serum with guanidine hydrochloride. Concanavalin A precipitated a large por...

journal_title：Gastroenterology

authors： Kitamura T,Yoshioka K,Ehara M,Akedo H

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with Barrett's esophagus (BE) have a risk of esophageal adenocarcinoma of approximately 0.5% per year. Patients may have difficulty understanding this risk. This study assessed the perceived risk of cancer in patients with BE, and correlated their risk estimates with their health care use beh...

journal_title：Gastroenterology

authors： Shaheen NJ,Green B,Medapalli RK,Mitchell KL,Wei JT,Schmitz SM,West LM,Brown A,Noble M,Sultan S,Provenzale D

更新日期：2005-08-01 00:00:00

abstract：:Hydrolysis of small peptides, like disaccharide hydrolysis, is an important function of the intestinal brush border, but little is known of the individual human peptidases. The purposes of this study were to detect all human brush border enzymes hydrolyzing dipeptides and tripeptides, identify the most discriminating ...

journal_title：Gastroenterology

authors： Tobey N,Heizer W,Yeh R,Huang TI,Hoffner C

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND & AIMS:Approximately 10% of children on the liver transplant wait-list in the United States die every year. We examined deceased donor liver offer acceptance patterns and their contribution to pediatric wait-list mortality. METHODS:We performed a retrospective cohort study of children on the US liver transp...

journal_title：Gastroenterology

authors： Hsu EK,Shaffer ML,Gao L,Sonnenday C,Volk ML,Bucuvalas J,Lai JC

更新日期：2017-10-01 00:00:00

abstract：:The effect of somatostatin 28, a noval intestinal peptide containing somatostatin in its C-terminal portion, was tested on basal exocrine pancreatic secretion on conscious dogs and after stimulation by secretin (1 CU x kg-1 x hr-1), caerulein (37.5 ng x kg-1 x hr-1) or secretin (2 CU x kg-1 x hr-1) caerulein (37.5 ng ...

journal_title：Gastroenterology

authors： Susini C,Esteve JP,Vaysse N,Pradayrol L,Ribet A

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND & AIMS:The mechanisms by which mutations in the familial intrahepatic cholestasis-1 gene cause Byler's disease (progressive familial intrahepatic cholestasis type 1) are unknown. METHODS:Interactions among the apical sodium-dependent bile acid transporter, the farnesoid X receptor (FXR), and familial intrah...

journal_title：Gastroenterology

authors： Chen F,Ananthanarayanan M,Emre S,Neimark E,Bull LN,Knisely AS,Strautnieks SS,Thompson RJ,Magid MS,Gordon R,Balasubramanian N,Suchy FJ,Shneider BL

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND & AIMS:Chronic hepatitis C virus infection activates an intrahepatic immune response, leading to increased expression of interferon (IFN)-stimulated genes and activation of natural killer (NK) cells-the most prevalent innate immune cell in the liver. We investigated whether the elimination of hepatitis C vir...

journal_title：Gastroenterology

authors： Serti E,Chepa-Lotrea X,Kim YJ,Keane M,Fryzek N,Liang TJ,Ghany M,Rehermann B

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND & AIMS:Biliary epithelial cells (BECs) are considered to be a source of regenerating hepatocytes when hepatocyte proliferation is compromised. However, there is still controversy about the extent to which BECs can contribute to the regenerating hepatocyte population, and thereby to liver recovery. To investi...

journal_title：Gastroenterology

authors： Choi TY,Ninov N,Stainier DY,Shin D

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND & AIMS:The hypothesis that progastrin-derived peptides act as autocrine growth factors for colorectal carcinomas has generated considerable interest. However, the influence of autocrine gastrins on nontumorigenic colonic cells has not been investigated. This study tested the above hypothesis in the nontumori...

journal_title：Gastroenterology

authors： Hollande F,Imdahl A,Mantamadiotis T,Ciccotosto GD,Shulkes A,Baldwin GS

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND & AIMS:Neutrophils are generally thought to play an important proinflammatory role in the pathogenesis of inflammatory bowel disease. The objective of this study was to evaluate whether blocking the invasion of neutrophils by anti-L-selectin monoclonal antibodies modulates chemically induced colitis and how ...

journal_title：Gastroenterology

authors： Kühl AA,Kakirman H,Janotta M,Dreher S,Cremer P,Pawlowski NN,Loddenkemper C,Heimesaat MM,Grollich K,Zeitz M,Farkas S,Hoffmann JC

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND & AIMS:Oral administration of ursodeoxycholic acid (UDCA) and cholesterol causes bile salt malabsorption; the former by competition for and the latter by down-regulation of ileal bile acid transporters. Because ileectomy in rats induces enterohepatic cycling of bilirubin, the hypothesis that dietary steroids...

journal_title：Gastroenterology

authors： Méndez-Sánchez N,Brink MA,Paigen B,Carey MC

更新日期：1998-09-01 00:00:00

abstract：:Circadian changes in drug absorption have been documented for several orally administered drugs in humans. To determine whether gastric emptying could account for these changes, morning (8 AM) and evening (8 PM) gastric emptying rates were measured in 16 healthy male subjects synchronized with diurnal activity and noc...

journal_title：Gastroenterology

authors： Goo RH,Moore JG,Greenberg E,Alazraki NP

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Fiber and water-holding agents are used for the treatment of constipation. In what may appear to be a paradox, they are sometimes also used for the treatment of diarrhea; it has been proposed that they sequester water from liquid stools and/or increase the ratio of fecal solids to fecal water and thereby imp...

journal_title：Gastroenterology

authors： Eherer AJ,Santa Ana CA,Porter J,Fordtran JS

更新日期：1993-04-01 00:00:00

abstract：:Boron may be beneficial for bone growth and maintenance, central nervous system function, and the inflammatory response, and silicon may be beneficial for bone maintenance and wound healing. Fluoride is not an essential element but amounts provided by contamination may be beneficial for bone strength. Fluoride toxicit...

journal_title：Gastroenterology

authors： Nielsen FH

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND & AIMS:The vagus nerve negatively regulates macrophage cytokine production via the release of acetylcholine (ACh) and activation of nicotinic acetylcholine receptors (nAChR). In various models of intestinal inflammation, vagus nerve efferent stimulation ameliorates disease. Given the actively constrained cyt...

journal_title：Gastroenterology

authors： van der Zanden EP,Snoek SA,Heinsbroek SE,Stanisor OI,Verseijden C,Boeckxstaens GE,Peppelenbosch MP,Greaves DR,Gordon S,De Jonge WJ

更新日期：2009-09-01 00:00:00

abstract：:Gastric and esophageal emptying were assessed using scintigraphic techniques in 12 patients with progressive systemic sclerosis and 22 normal volunteers. Esophageal emptying was significantly delayed in the patient group, with 7 of the 12 patients beyond the normal range. Gastric emptying was slower in patients than i...

journal_title：Gastroenterology

authors： Maddern GJ,Horowitz M,Jamieson GG,Chatterton BE,Collins PJ,Roberts-Thomson P

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND & AIMS:It has been proposed that activation of the sympathetic nervous system causes a rightward shift in the renal autoregulatory curve such that renal blood flow is critically dependent on renal perfusion pressure and that this contributes to the development of the hepatorenal syndrome. The aims of the stu...

journal_title：Gastroenterology

authors： Stadlbauer V,Wright GA,Banaji M,Mukhopadhya A,Mookerjee RP,Moore K,Jalan R

更新日期：2008-01-01 00:00:00

abstract：:The growth rate of 31 asymptomatic hepatocellular carcinomas (diameter less than or equal to 5 cm) discovered in 28 patients by a prospective screening program was determined by real-time ultrasonography over 36-860 days. Except for one tumor that shrank on follow-up, the doubling time ranged from 29 to 398 days, with...

journal_title：Gastroenterology

authors： Sheu JC,Sung JL,Chen DS,Yang PM,Lai MY,Lee CS,Hsu HC,Chuang CN,Yang PC,Wang TH

更新日期：1985-08-01 00:00:00