Eosinophilic gastroenteritis in extreme allergy. Immunopathological comparison with nonallergic gastrointestinal disease.

abstract：BACKGROUND & AIMS:Beta-blockers are extensively used to prevent variceal bleeding in patients with large esophageal varices. It is not established if beta-blockers delay the growth of small varices. METHODS:A total of 161 patients with cirrhosis and small esophageal varices (F1 according to the classification of Beppu...

journal_title：Gastroenterology

authors： Merkel C,Marin R,Angeli P,Zanella P,Felder M,Bernardinello E,Cavallarin G,Bolognesi M,Donada C,Bellini B,Torboli P,Gatta A,Gruppo Triveneto per l'Ipertensione Portale.

更新日期：2004-08-01 00:00:00

abstract：:Ursodeoxycholic acid, the 7 beta-hydroxy epimer of chenodeoxycholic acid, is more hydrophilic and less hepatotoxic than chenodeoxycholic acid. Because "lagodeoxycholic acid," the 12 beta-hydroxy epimer of deoxycholic acid, is also more hydrophilic than deoxycholic acid, it was hypothesized that it should also be less ...

journal_title：Gastroenterology

authors： Schmassmann A,Angellotti MA,Clerici C,Hofmann AF,Ton-Nu HT,Schteingart CD,Marcus SN,Hagey LR,Rossi SS,Aigner A

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND & AIMS:Fish is a rich source of n-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA). Although consumption of fish and n-3 PUFA has been reported to protect against the development of some types of cancer, little is known ab...

journal_title：Gastroenterology

authors： Sawada N,Inoue M,Iwasaki M,Sasazuki S,Shimazu T,Yamaji T,Takachi R,Tanaka Y,Mizokami M,Tsugane S,Japan Public Health Center-Based Prospective Study Group.

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND & AIMS:Apart from its importance as an acid secretogogue, the role of histamine as a downstream target of gastrin has not been fully explored. Previous studies have shown that the combination of hypergastrinemia and Helicobacter infection resulted in accelerated gastric cancer in mice. We used this model to ...

journal_title：Gastroenterology

authors： Takaishi S,Cui G,Frederick DM,Carlson JE,Houghton J,Varro A,Dockray GJ,Ge Z,Whary MT,Rogers AB,Fox JG,Wang TC

更新日期：2005-06-01 00:00:00

abstract：:We studied the effect of chronic aspirin ingestion on gastroduodenal epithelial proliferation by feeding rats aspirin in the drinking water. A control group of rats received plain water. At the end of 4 wk, [3H]-thymidine was given intravenously to label proliferating cells, and the rats were killed 1 h later. Section...

journal_title：Gastroenterology

authors： Eastwood GL,Quimby GF

更新日期：1982-05-01 00:00:00

abstract：:We investigated whether intrapancreatic coagulation, with deposition of the fibrinogen-γ dimer (Fib-γD) and hypoxia, affect the severity of acute pancreatitis (AP) in mice. Pancreata of mice with AP induced by administration of cerulein or by L-arginine, or from patients with pancreatitis, had increased deposition of ...

journal_title：Gastroenterology

authors： Park MJ,Iyer S,Xue X,Bragazzi Cunha J,Gu S,Moons D,Pipe SW,Williams JA,Simeone DM,Shah YM,Omary MB

更新日期：2018-05-01 00:00:00

abstract：:The mechanism of acute ulceration and the nature of mucosal protective mechanisms were investigated in rabbit antrum, which is more resistant to injury than fundus of the same species, with particular reference to the relationship between H+ back diffusion, tissue acidification, and occurrence of ulceration. Exposure ...

journal_title：Gastroenterology

authors： Kivilaakso E,Barzilai A,Schiessel R,Fromm D,Silen W

更新日期：1981-01-01 00:00:00

abstract：:To find a possible explanation for the selective hepatic conjugation of bile acids with glycine or taurine, the N-acyl amidates of cholic acid and a number of amino acids and amino acid analogues were synthesized, and their susceptibility to hydrolysis by pancreatic juice, gastric juice, serum, or small intestinal muc...

journal_title：Gastroenterology

authors： Huijghebaert SM,Hofmann AF

更新日期：1986-02-01 00:00:00

abstract：:Developmental aspects of the intestinal transport of biotin were examined in suckling (16 day old) and weanling (24 day old) rats using the everted sac technique. The results were compared with those of adult rats previously reported by us using the same intestinal preparation. Transport of biotin was linear for 20 mi...

journal_title：Gastroenterology

authors： Said HM,Redah R

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND & AIMS:Hypercoagulable states may play an important role in the pathogenesis of colon ischemia. Aim of this study was to assess this hypothesis investigating the role of acquired and hereditary thrombotic risk factors in patients with definite diagnosis of colon ischemia. METHODS:We compared the frequency o...

journal_title：Gastroenterology

authors： Koutroubakis IE,Sfiridaki A,Theodoropoulou A,Kouroumalis EA

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND & AIMS:Surgical management of pancreatic cancer depends on tumor resectability and staging. This study evaluated a new in vivo technique, fiberoptic confocal fluorescence microscopy (FCFM), for detection and staging of pancreatic tumors in rats. METHODS:FCFM was used with a protease-activated fluorescent ma...

journal_title：Gastroenterology

authors： Ignat M,Aprahamian M,Lindner V,Altmeyer A,Perretta S,Dallemagne B,Mutter D,Marescaux J

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND & AIMS:Cholangiocarcinomas appear to arise from the malignant transformation of cholangiocytes lining the biliary tract. Because the development of an in vitro model of malignant transformation can provide a powerful new tool for establishing critical events governing the molecular pathogenesis of cholangioc...

journal_title：Gastroenterology

authors： Lai GH,Zhang Z,Shen XN,Ward DJ,Dewitt JL,Holt SE,Rozich RA,Hixson DC,Sirica AE

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND & AIMS:Intestinal myofibroblasts are known to respond to inflammatory signals and may play a role in Crohn's disease-associated fibrosis. However, putative involvement by myofibroblasts in innate immune responses as part of intestinal host defense has not been characterized. We therefore analyzed expression ...

journal_title：Gastroenterology

authors： Otte JM,Rosenberg IM,Podolsky DK

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND & AIMS:To date, computed tomographic (CT) colonography has been compared with an imperfect test, colonoscopy, and has been mainly assessed in patients with positive screening test results or symptoms. Therefore, the available data may not apply to screening of patients with a personal or family history of co...

journal_title：Gastroenterology

authors： Van Gelder RE,Nio CY,Florie J,Bartelsman JF,Snel P,De Jager SW,Van Deventer SJ,Laméris JS,Bossuyt PM,Stoker J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND & AIMS:The complications of diverticulosis cause considerable morbidity in the United States; health care expenditures for this disorder are estimated to be $2.5 billion per year. Many physicians and patients believe that a high-fiber diet and frequent bowel movements prevent the development of diverticulosi...

journal_title：Gastroenterology

authors： Peery AF,Barrett PR,Park D,Rogers AJ,Galanko JA,Martin CF,Sandler RS

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND & AIMS:De novo hepatitis B virus (HBV)-related hepatitis after chemotherapy results in high morbidity and mortality. We evaluate the clinical course of de novo HBV-related hepatitis after chemotherapy. METHODS:Two hundred forty-four consecutive hepatitis B surface antigen (HBsAg)-negative lymphoma patients ...

journal_title：Gastroenterology

authors： Hui CK,Cheung WW,Zhang HY,Au WY,Yueng YH,Leung AY,Leung N,Luk JM,Lie AK,Kwong YL,Liang R,Lau GK

更新日期：2006-07-01 00:00:00

abstract：:A case of acute hypervitaminosis A complicating viral hepatitis is reported. Twenty days after presenting with hepatitis B, a 42-yr-old vegetarian developed acute hypervitaminosis A in the absence of recent, massive exposure to the vitamin. Findings included headache, confusion, skin desquamation, and hypercalcemia. P...

journal_title：Gastroenterology

authors： Hatoff DE,Gertler SL,Miyai K,Parker BA,Weiss JB

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Diffuse-type gastric cancer (GC) is currently subdivided into signet-ring cell carcinoma (SRCC) and non-SRCC, referred to as poorly cohesive carcinoma not otherwise specified (PCC-NOS). Although these subtypes are considered to be independent, they often coexist in the same tumors, raising a questio...

journal_title：Gastroenterology

authors： Togasaki K,Sugimoto S,Ohta Y,Nanki K,Matano M,Takahashi S,Fujii M,Kanai T,Sato T

更新日期：2020-11-17 00:00:00

abstract：:Effects of opiates on intestinal motor activity and transport of water and electrolytes have been studied separately in previous investigations. The aim of these experiments was to evaluate simultaneously the effects of a synthetic opiate, loperamide, on motor activity and transport in the human intestine. Jejunal, il...

journal_title：Gastroenterology

authors： Kachel G,Ruppin H,Hagel J,Barina W,Meinhardt M,Domschke W

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND & AIMS:No controlled trial has examined the clinical efficacy of antibiotics in small bowel bacterial overgrowth. METHODS:Ten patients with bacterial overgrowth-related diarrhea underwent the following five 7-day treatment periods: untreated (control period), then placebo, and subsequently, in random order ...

journal_title：Gastroenterology

authors： Attar A,Flourié B,Rambaud JC,Franchisseur C,Ruszniewski P,Bouhnik Y

更新日期：1999-10-01 00:00:00

abstract：:A numerically important group of patients with functional gastrointestinal disorders have chronic symptoms that can be attributed to the gastroduodenal region. Based on the consensus opinion of an international panel of clinical investigators who reviewed the available evidence, a classification of the functional gast...

journal_title：Gastroenterology

authors： Tack J,Talley NJ,Camilleri M,Holtmann G,Hu P,Malagelada JR,Stanghellini V

更新日期：2006-04-01 00:00:00

abstract：:A 44-yr-old woman with non-A, non-B hepatitis developed agranulocytosis and absence of marrow granulocyte precursor cells with only mild involvement of other blood elements. The agranulocytosis was complicated by gram-negative septicemia, successfully treated with antibiotic therapy. Marrow recovery followed 2 wk of s...

journal_title：Gastroenterology

authors： Vande Stouwe RA,Attia AA,Karanas A,Ciavarella D,Grieco MH

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND & AIMS:Intestinal microbes induce homeostatic mucosal immune responses, but can also cause inappropriate immune activation in genetically susceptible hosts. Although immune responses to bacterial products have been studied extensively, little is known about how intestinal inflammation affects functions of co...

journal_title：Gastroenterology

authors： Patwa LG,Fan TJ,Tchaptchet S,Liu Y,Lussier YA,Sartor RB,Hansen JJ

更新日期：2011-11-01 00:00:00

abstract：:Several areas regarding Helicobacter pylori that need improvement or clarification in the United States include treatment of dyspepsia, physician education on disease associations with H. pylori, and evidence from U.S. studies that 7-day H. pylori eradication regimens are more effective than current regimens. Dyspepsi...

journal_title：Gastroenterology

authors： Freston JW

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND & AIMS:Pancreatic ductal adenocarcinoma (PDAC) is a highly invasive and metastatic disease for which conventional treatments are of limited efficacy. A number of agents in development are potential anti-invasive and antimetastatic agents, including the Src kinase inhibitor dasatinib. The aim of this study wa...

journal_title：Gastroenterology

authors： Morton JP,Karim SA,Graham K,Timpson P,Jamieson N,Athineos D,Doyle B,McKay C,Heung MY,Oien KA,Frame MC,Evans TR,Sansom OJ,Brunton VG

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND & AIMS:Platelet-activating factor (PAF) is increased during relapse of ulcerative colitis. In animal models of experimental colitis, specific inhibition of PAF has reduced inflammation. The aim of this study was to evaluate the efficacy and safety of the PAF antagonist SR27417A in moderately active UC. METH...

journal_title：Gastroenterology

authors： Stack WA,Jenkins D,Vivet P,Hawkey CJ

更新日期：1998-12-01 00:00:00

abstract：:A 20-yr-old man developed recurrent respiratory symptoms and left lower lobe pneumonia 14 yr after long-segment colonic interposition for corrosive esophageal injury. A fistula, from a redundant supradiaphragmatic pouch of colon to a subsegmental bronchus of the lower lobe of the left lung, was discovered and treated ...

journal_title：Gastroenterology

authors： Perlmutter DH,Tapper D,Teele RL,Winter HS

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND & AIMS:Deoxycholate (DC) has proapoptotic and tumorigenic effects in different cell types of the gastrointestinal tract. Exposure of BHK-21 (stromal) cells to DC induces Ca(2+) entry at the plasma membrane, which affects intracellular Ca(2+) signaling. We assessed whether DC-induced increases in [Ca(2+)] can...

journal_title：Gastroenterology

authors： Gerbino A,Ranieri M,Lupo S,Caroppo R,Debellis L,Maiellaro I,Caratozzolo MF,Lopez F,Colella M

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND/AIMS:Carbonic anhydrase activity plays a role in electrolyte transport in many tissues. This study examined the effect of the carbonic anhydrase inhibitor acetazolamide on human basal and prostaglandin E2- and acid-stimulated duodenal mucosal bicarbonate secretion and transmucosal electrical potential differ...

journal_title：Gastroenterology

authors： Knutson TW,Koss MA,Hogan DL,Isenberg JI,Knutson L

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND & AIMS:Senescence prevents cellular transformation. We investigated whether vascular endothelial growth factor (VEGF) signaling via its receptor, VEGFR2, regulates senescence and proliferation of tumor cells in mice with colitis-associated cancer (CAC). METHODS:CAC was induced in VEGFR2(ΔIEC) mice, which do...

journal_title：Gastroenterology

authors： Foersch S,Sperka T,Lindner C,Taut A,Rudolph KL,Breier G,Boxberger F,Rau TT,Hartmann A,Stürzl M,Wittkopf N,Haep L,Wirtz S,Neurath MF,Waldner MJ

更新日期：2015-07-01 00:00:00