Abstract:
:A 44-yr-old woman with non-A, non-B hepatitis developed agranulocytosis and absence of marrow granulocyte precursor cells with only mild involvement of other blood elements. The agranulocytosis was complicated by gram-negative septicemia, successfully treated with antibiotic therapy. Marrow recovery followed 2 wk of supportive therapy. Before reversal of the agranulocytosis, a future bone marrow transplant was a consideration, making the use of therapeutic granulocyte transfusions, with their ability to sensitize the recipient, potentially harmful. Experience in this case indicates that agranulocytosis associated with non-A, non-B hepatitis may be reversible, and supports the use of supportive care including appropriate antibiotics, and if necessary, granulocyte transfusions, pending marrow recovery.
journal_name
Gastroenterologyjournal_title
Gastroenterologyauthors
Vande Stouwe RA,Attia AA,Karanas A,Ciavarella D,Grieco MHsubject
Has Abstractpub_date
1983-07-01 00:00:00pages
186-9issue
1eissn
0016-5085issn
1528-0012pii
S0016508583001535journal_volume
85pub_type
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