Transient agranulocytosis associated with non-A, non-B hepatitis.

Abstract:

:A 44-yr-old woman with non-A, non-B hepatitis developed agranulocytosis and absence of marrow granulocyte precursor cells with only mild involvement of other blood elements. The agranulocytosis was complicated by gram-negative septicemia, successfully treated with antibiotic therapy. Marrow recovery followed 2 wk of supportive therapy. Before reversal of the agranulocytosis, a future bone marrow transplant was a consideration, making the use of therapeutic granulocyte transfusions, with their ability to sensitize the recipient, potentially harmful. Experience in this case indicates that agranulocytosis associated with non-A, non-B hepatitis may be reversible, and supports the use of supportive care including appropriate antibiotics, and if necessary, granulocyte transfusions, pending marrow recovery.

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Vande Stouwe RA,Attia AA,Karanas A,Ciavarella D,Grieco MH

subject

Has Abstract

pub_date

1983-07-01 00:00:00

pages

186-9

issue

1

eissn

0016-5085

issn

1528-0012

pii

S0016508583001535

journal_volume

85

pub_type

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