Effect of psyllium, calcium polycarbophil, and wheat bran on secretory diarrhea induced by phenolphthalein.

abstract：:The case of a 21-yr-old man, who died in cachexia after 2 yr of intermittent abdominal pain, bouts of diarrhea, and anorexia, is reported. Laboratory tests performed shortly before death disclosed signs of malabsorption. Radiologic examination of the gastrointestinal tract showed a coarse mucosal relief in the upper j...

journal_title：Gastroenterology

authors： Jacobs E,Ardichvili D,Perissino A,Gottignies P,Hanssens JF

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND/AIMS:The frequency of colorectal adenomas, the precursor lesions for most cases of colorectal carcinoma, has been generally measured as prevalence rates of adenomas at autopsy or colonoscopy. The aim of this study was to estimate the incidence rate of adenomas and compare it with the adenoma recurrence rate....

journal_title：Gastroenterology

authors： Neugut AI,Jacobson JS,Ahsan H,Santos J,Garbowski GC,Forde KA,Treat MR,Waye J

更新日期：1995-02-01 00:00:00

abstract：:The effects of vasopressin on blood flow in the superior mesenteric artery and on mean arterial pressure and portal venous pressure were measured in 7 rhesus monkeys. Vasopressin was injected, as either a bolus, or infused both intravenously and intraarterially to assess the influence of the route of administration up...

journal_title：Gastroenterology

authors： Freedman AR,Kerr JC,Swan KG,Hobson RW

更新日期：1978-05-01 00:00:00

abstract：:A case of a 29-year-old woman who has had two episodes both clinically and biochemically consistent with acute fatty liver of pregnancy is described. These episodes occurred in two successive pregnancies, and liver biopsy confirmed the diagnosis in the second pregnancy. Both pregnancies were managed by prompt fetal de...

journal_title：Gastroenterology

authors： Schoeman MN,Batey RG,Wilcken B

更新日期：1991-02-01 00:00:00

abstract：:Spinal cord stimulation is an increasingly popular form of pain treatment. An electrode positioned on the dorsal aspect of the spinal cord at the level of the nerve roots from the painful area stimulates the spinal cord. Current from the electrode is supplied by a pulse generator in the lower anterior abdominal wall. ...

journal_title：Gastroenterology

authors： Kemler MA,Barendse GA,Van Kleef M

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND & AIMS:The ratio of liver size to body weight (hepatostat) is tightly controlled, but little is known about how the physiologic functions of the liver help determine its size. Livers of mice repopulated with human hepatocytes (humanized livers) grow to larger than normal; the human hepatocytes do not recogni...

journal_title：Gastroenterology

authors： Naugler WE,Tarlow BD,Fedorov LM,Taylor M,Pelz C,Li B,Darnell J,Grompe M

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND & AIMS:The maintenance of the intestinal mucosal barrier may be energy dependent. Tacrolimus is a potent immunosuppressive drug that decreases mitochondrial adenosine triphosphate production and increases intestinal permeability in animals. METHODS:Twelve liver graft recipients receiving tacrolimus, 9 healt...

journal_title：Gastroenterology

authors： Gabe SM,Bjarnason I,Tolou-Ghamari Z,Tredger JM,Johnson PG,Barclay GR,Williams R,Silk DB

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND & AIMS:Fully covered self-expanding metal stents (FCSEMS) are gaining acceptance for the treatment of benign biliary strictures. We performed a large prospective multinational study to study the ability to remove these stents after extended indwell and the frequency and durability of stricture resolution. M...

journal_title：Gastroenterology

authors： Devière J,Nageshwar Reddy D,Püspök A,Ponchon T,Bruno MJ,Bourke MJ,Neuhaus H,Roy A,González-Huix Lladó F,Barkun AN,Kortan PP,Navarrete C,Peetermans J,Blero D,Lakhtakia S,Dolak W,Lepilliez V,Poley JW,Tringali A,Costam

更新日期：2014-08-01 00:00:00

abstract：:We studied the appearance of specific secretory immunoglobulin A (IgA) antibody in bile after inoculation of live Giardia lamblia trophozoites into rat intestine. Serial bile specimens collected before and after inoculation of trophozoites were assayed for IgA antibodies by indirect immunofluorescence. Secretory IgA a...

journal_title：Gastroenterology

authors： Loftness TJ,Erlandsen SL,Wilson ID,Meyer EA

更新日期：1984-11-01 00:00:00

abstract：:Three generations of a kindred comprising 50 individuals are described in which recurrent intrahepatic cholestasis of pregnancy has occurred with high frequency. A uniform expression and complete penetrance of the trait in the women of a limited "affected" portion of the kindred (6 affected of 10 women), along with th...

journal_title：Gastroenterology

authors： Holzbach RT,Sivak DA,Braun WE

更新日期：1983-07-01 00:00:00

abstract：:We studied the procoagulant activity of peripheral blood monocytes in 41 patients with severe obstructive jaundice and in 27 nonjaundiced control patients using a one-stage clotting assay. Mononuclear cells from jaundiced patients, tested immediately after isolation, expressed low levels of procoagulant activity, whic...

journal_title：Gastroenterology

authors： Semeraro N,Montemurro P,Chetta G,Altomare DF,Giordano D,Colucci M

更新日期：1989-03-01 00:00:00

abstract：:We have investigated the effect of oral cisapride (10 mg t.i.d.) in a double-blind, placebo-controlled trial in 26 patients with upper gut dysmotility: 11 with gastroparesis (8 diabetic, 3 idiopathic) and 15 with chronic idiopathic intestinal pseudoobstruction. Patients were evaluated at entry and at the end of the 6-...

journal_title：Gastroenterology

authors： Camilleri M,Malagelada JR,Abell TL,Brown ML,Hench V,Zinsmeister AR

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND & AIMS:Lactase is the intestinal disaccharidase responsible for digestion of lactose, the predominant carbohydrate in milk. Transcription of the lactase gene is activated during enterocyte differentiation. We have characterized the interaction between the lactase promoter and Cdx2, a homeodomain protein invo...

journal_title：Gastroenterology

authors： Fang R,Santiago NA,Olds LC,Sibley E

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Bacterial proteoglycan-derived muramyl dipeptide (MDP) activates the intracellular NOD2/CARD15 gene product. How intestinal epithelial cells take up MDP is poorly understood. We hypothesized that the intestinal apical di-/tripeptide transporter, hPepT1, transports MDP, thereby activating downstream ...

journal_title：Gastroenterology

authors： Vavricka SR,Musch MW,Chang JE,Nakagawa Y,Phanvijhitsiri K,Waypa TS,Merlin D,Schneewind O,Chang EB

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND & AIMS:Cancer progression/metastases and embryonic development share many properties including cellular plasticity, dynamic cell motility, and integral interaction with the microenvironment. We hypothesized that the heterogeneous nature of hepatocellular carcinoma (HCC), in part, may be owing to the presence...

journal_title：Gastroenterology

authors： Yamashita T,Ji J,Budhu A,Forgues M,Yang W,Wang HY,Jia H,Ye Q,Qin LX,Wauthier E,Reid LM,Minato H,Honda M,Kaneko S,Tang ZY,Wang XW

更新日期：2009-03-01 00:00:00

abstract：:Phenobarbital response, bile pigment composition, and the fractional biliary excretion ratio of bilirubin were studied in nine children with Crigler-Najjar disease. In five children, serum bilirubin levels decreased during phenobarbital treatment by 26% or more and the pigment composition in bile changed with a decrea...

journal_title：Gastroenterology

authors： Sinaasappel M,Jansen PL

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND/AIMS:Antifungal therapy cures esophageal candidiasis in most patients with acquired immunodeficiency syndrome, but the subsequent course of these patients is not established. This study examines the natural history of esophageal candidiasis after successful treatment. METHODS:Patients with endoscopic and cl...

journal_title：Gastroenterology

authors： Laine L

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND & AIMS:The aim of this study was to generate an improved prognostic model for predicting recurrence in liver transplant candidates with hepatocellular carcinoma (HCC). METHODS:Predictors of recurrence were tested by a Cox model analysis in a training cohort of 537 patients transplanted for HCC. A prognostic...

journal_title：Gastroenterology

authors： Duvoux C,Roudot-Thoraval F,Decaens T,Pessione F,Badran H,Piardi T,Francoz C,Compagnon P,Vanlemmens C,Dumortier J,Dharancy S,Gugenheim J,Bernard PH,Adam R,Radenne S,Muscari F,Conti F,Hardwigsen J,Pageaux GP,Chazouill

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND/AIMS:Spasmolytic polypeptide (SP) is a trefoil peptide expressed in the digestive tract. This study aimed to determine the structure and distribution of SP expression in the rat gastrointestinal tract. METHODS:The structure of rat SP was determined from the sequence of complementary DNAs isolated from antra...

journal_title：Gastroenterology

authors： Jeffrey GP,Oates PS,Wang TC,Babyatsky MW,Brand SJ

更新日期：1994-02-01 00:00:00

abstract：:Hepatic plasma flow was assessed with sorbitol (hepatic extraction = 0.96) at steady state. After infusion of 50 mg/min for 3 h, total and renal sorbitol clearances were calculated, and the extrarenal clearance was obtained by taking the difference between the two. In normal volunteers, the mean (+/- SD) extrarenal so...

journal_title：Gastroenterology

authors： Zeeh J,Lange H,Bosch J,Pohl S,Loesgen H,Eggers R,Navasa M,Chesta J,Bircher J

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND & AIMS:Interferon-free direct-acting antiviral (DAA) therapies are effective in patients with hepatitis C virus-induced cryoglobulinemia vasculitis (HCV-CV). We analyzed blood samples from patients with HCV-CV before and after DAA therapy to determine mechanisms of these drugs and their effects on cellular i...

journal_title：Gastroenterology

authors： Comarmond C,Garrido M,Pol S,Desbois AC,Costopoulos M,Le Garff-Tavernier M,Si Ahmed SN,Alric L,Fontaine H,Bellier B,Maciejewski A,Rosenzwajg M,Klatzmann D,Musset L,Poynard T,Cacoub P,Saadoun D

更新日期：2017-06-01 00:00:00

abstract：:The amount of bile acid excreted via an ileostomy at the end of the ileum should give an estimate of the amount of bile acid transported to the colon. In the present study, 8 patients with ileostomies at the end of the ileum but without disease or resection of the small intestine excreted 1690 +/- 205 mumol/day (mean ...

journal_title：Gastroenterology

authors： Stiehl A,Raedsch R,Rudolph G

更新日期：1988-05-01 00:00:00

abstract：:This study was designed to investigate the location, specificity, and significance of antibody-containing cells in the liver. After intestinal administration of cholera toxin, high numbers of specific antibody-containing cells appeared in the liver during the early priming period and after boosting. In contrast, a sig...

journal_title：Gastroenterology

authors： Altorfer J,Hardesty SJ,Scott JH,Jones AL

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND & AIMS:Giardiasis causes malabsorptive diarrhea, and symptoms can be present in the absence of any significant morphologic injury to the intestinal mucosa. The effects of giardiasis on epithelial permeability in vivo remain unknown, and the role of T cells and myosin light chain kinase (MLCK) in altered inte...

journal_title：Gastroenterology

authors： Scott KG,Meddings JB,Kirk DR,Lees-Miller SP,Buret AG

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND & AIMS:Omeprazole is metabolized by cytochrome P450 (CYP2C19). The activity of this enzyme is polymorphic, with incidences of poor metabolizers (PMs), heterozygous extensive metabolizers (EMs), and homozygous EMs in white populations of 3%, 30%, and 67%, respectively. The importance of the CYP2C19 polymorphi...

journal_title：Gastroenterology

authors： Sagar M,Tybring G,Dahl ML,Bertilsson L,Seensalu R

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND & AIMS:Crohn's disease (CD) and ulcerative colitis (UC) are associated with chronic tissue damage and continuous tissue repair. A central, but not well-characterized, event during this process is the migration of activated fibroblasts to the wound. METHODS:Human colonic lamina propria fibroblasts (CLPF) wer...

journal_title：Gastroenterology

authors： Leeb SN,Vogl D,Gunckel M,Kiessling S,Falk W,Göke M,Schölmerich J,Gelbmann CM,Rogler G

更新日期：2003-11-01 00:00:00

abstract：:Hepatic cytochrome P450 levels in male rats fall after portal vein ligation, a procedure that produces total hepatic bypass of portal blood. The present study was undertaken to examine whether changes in sex hormone metabolism could account for these lowered cytochrome P450 levels. Portal vein ligation resulted in tes...

journal_title：Gastroenterology

authors： Farrell GC,Koltai A,Zaluzny L,Murray M

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND & AIMS:The risk for colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD) could have changed over time, with changes in treatment options. We studied CRC risk in a nationwide cohort of 47,374 Danish patients with IBD over a 30-year period. METHODS:We determined relative risk (RR) values ...

journal_title：Gastroenterology

authors： Jess T,Simonsen J,Jørgensen KT,Pedersen BV,Nielsen NM,Frisch M

更新日期：2012-08-01 00:00:00

abstract：:Four Puerto Rican sisters had recurrent prolonged cholestasis of pregnancy without preexisting or intercurrent hepatic disorders. Available information was reviewed on the course, mechanism, and sequelae of prolonged recurrent cholestasis after 14 pregnancies in the 4 sisters. Etiologic, clinical, laboratory, radiolog...

journal_title：Gastroenterology

authors： Leevy CB,Koneru B,Klein KM

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND & AIMS:Linaclotide is a minimally absorbed agonist of guanylate cyclase-C (GUCY2C or GC-C) that reduces symptoms associated with irritable bowel syndrome with constipation (IBS-C). Little is known about the mechanism by which linaclotide reduces abdominal pain in patients with IBS-C. METHODS:We determined t...

journal_title：Gastroenterology

authors： Castro J,Harrington AM,Hughes PA,Martin CM,Ge P,Shea CM,Jin H,Jacobson S,Hannig G,Mann E,Cohen MB,MacDougall JE,Lavins BJ,Kurtz CB,Silos-Santiago I,Johnston JM,Currie MG,Blackshaw LA,Brierley SM

更新日期：2013-12-01 00:00:00