Abstract:
:The analgesic efficacy of the novel anxiolytic buspirone in tests of acute thermal, mechanical and formalin-induced chemical-inflammatory pain were examined. Buspirone produced dose- and time-dependent analgesia in all nociceptive tests, with greatest effects against chemical and mechanical pain. Buspirone was less potent in the thermal pain test. Locomotor and overt behavioral activities were unaffected at any dose tested. These data suggest the potential use of buspirone in the management of specific types of pain.
journal_name
Painjournal_title
Painauthors
Giordano J,Rogers Ldoi
10.1016/0304-3959(89)90181-4subject
Has Abstractpub_date
1989-10-01 00:00:00pages
109-113issue
1eissn
0304-3959issn
1872-6623pii
00006396-198910000-00015journal_volume
39pub_type
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