The proposed role of plasma NT pro-brain natriuretic peptide in assessing cardiac remodelling in hypertensive African subjects.

abstract：AIM:Flow-mediated dilatation (FMD) and retinal vascular analysis (RVA) may assist in predicting cardiovascular disease (CVD) but are poorly characterised in South Africa. We recorded baseline FMD and retinal vascular widths in healthy participants, and investigated associations with cardiovascular risk factors. METHOD...

journal_title：Cardiovascular journal of Africa

authors： Marincowitz C,Webster I,Westcott C,Goswami N,de Boever P,Seidel G,Strijdom H

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:We aimed to determine the possible factors leading to re-operation in patients undergoing mechanical valve replacement and to investigate the relationship between valvular thrombus formation and mean platelet volume. METHODS:The medical records of 43 patients with mechanical valve implantation, who were adm...

journal_title：Cardiovascular journal of Africa

authors： Aydin E,Yapici F

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:The surgical approach for effusive constrictive pericarditis (ECP) has not been extensively studied. We present our institution's early and long-term results of pericardiectomy in our cohort of patients with ECP. METHODS:Diagnosis was made primarily by echocardiography. Right heart catheterisation was perfor...

journal_title：Cardiovascular journal of Africa

authors： Buyukbayrak F,Aksoy E,Tas S,Kirali K

更新日期：2013-09-01 00:00:00

abstract：:We researched hypertrophic cardiomyopathy (HCM) and long QT syndrome (LQTS) as models for studying the pathophysiology of arrhythmias and hypertrophy, and in the process we have had the opportunity to compare local disease profiles with global patterns. We trawled our database entries over the past 20 years to identif...

journal_title：Cardiovascular journal of Africa

authors： Heradien M,Goosen A,Moolman-Smook JC,Brink PA

更新日期：2007-09-01 00:00:00

abstract：:Behcet's syndrome is a systemic inflammatory disease associated with vasculitis, and arterial, venous and cardiac disorders. Thirty-eight Behcet's disease patients were examined prospectively with echocardiography, ultrasonography and computed tomography, and coagulation parameters were determined. Deep venous insuffi...

journal_title：Cardiovascular journal of Africa

authors： Ulusan Z,Karadag AS,Tasar M,Kalender M,Darcin OT

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:To assess the influence of diabetes mellitus on early morbidity and mortality following a femoro-popliteal bypass. METHODS:Clinical data on patients subjected to a prosthetic above-the-knee femoro-popliteal bypass for atherothrombotic disease over a four-year period in the Durban Metropolitan Vascular Servi...

journal_title：Cardiovascular journal of Africa

authors： Mulaudzi TV,Robbs JV,Paruk N,Pillay B,Madiba TE,Govindsamy V

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that the Tp-e interval, which on an electrocardiogram (ECG) is the interval between the peak and the end of the T wave, can be used as an index of transmural dispersion of ventricular repolarisation (TDR). Both Tp-e/QT and Tp-e/QTc ratios have also been used in that capacity. Howeve...

journal_title：Cardiovascular journal of Africa

authors： Kucuk M,Karadeniz C,Ozdemir R,Meşe T

更新日期：2018-11-01 00:00:00

abstract：:Cardiovascular disease (CVD) is the frontrunner in the disease spectrum of sub-Saharan Africa, with stroke and ischaemic heart disease ranked seventh and 14th as leading causes of death, respectively, on this sub-continent. Unfortunately, this region is also grappling with many communicable, maternal, neonatal and nut...

journal_title：Cardiovascular journal of Africa

authors： Ojji DB,Lamont K,Ojji OI,Egenti BN,Sliwa K

更新日期：2017-07-01 00:00:00

abstract：:Acute myocardial infarction is a rare complication of dobutamine stress echocardiography. We describe the case of a diabetic patient who presented with an anterior myocardial infarction complicated by an acute pulmonary oedema and cardiogenic collapse during dobutamine stress echocardiography, requiring five days' hos...

journal_title：Cardiovascular journal of Africa

authors： Yameogo NV,Mbaye A,Kagambega LJ,Dioum M,Diagne-Sow D,Kane M,Diack B,Kane A

更新日期：2013-06-23 00:00:00

abstract：:Peripheral arterial disease (PAD) represents a major public health problem due to its high and increasing prevalence, worldwide distribution, and significant morbidity and mortality rate. Female gender is a risk factor for PAD globally and especially in low-income countries. In this review, we summarise the present kn...

journal_title：Cardiovascular journal of Africa

authors： Comşa HI,Zdrenghea D,Man SC,Pop D

更新日期：2018-09-01 00:00:00

abstract：:Heparin-induced thrombocytopenia (HIT) is a rare but potentially devastating and life-threatening complication from using heparin. HIT not only causes thrombocytopenia, but it also carries an increased risk for fatal thrombotic complications. In this report, we describe the case of a patient in whom fatal HIT develope...

journal_title：Cardiovascular journal of Africa

authors： Nazli Y,Colak N,Demircelik B,Alpay MF,Cakir O,Cagli K

更新日期：2015-05-23 00:00:00

abstract：BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...

journal_title：Cardiovascular journal of Africa

authors： Siweya H,Monyeki KD

更新日期：2019-01-01 00:00:00

abstract：:Resistant hypertension is a common clinical problem in South Africa and is frequently associated with low renin and aldosterone levels, especially in black Africans. In South Africa, novel variants in the epithelial sodium channel (ENaC) have been described to be associated with varying degrees of hypokalaemia and hyp...

journal_title：Cardiovascular journal of Africa

authors： Freercks R,Meldau S,Jones E,Ensor J,Weimers-Willard C,Rayner B

更新日期：2017-09-23 00:00:00

abstract：OBJECTIVE:Circulatory failure due to acute arterial hypertension in the neonatal period is rare. This study was undertaken to assess the clinical and echocardiographic manifestations of circulatory failure resulting from acute neonatal hypertensive crisis. METHODS:Neonatal and cardiology databases from 2007 to 2010 we...

journal_title：Cardiovascular journal of Africa

authors： Louw J,Brown S,Thewissen L,Smits A,Eyskens B,Heying R,Cools B,Levtchenko E,Allegaert K,Gewillig M

更新日期：2013-04-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...

journal_title：Cardiovascular journal of Africa

authors： Yolcu M,Gunesdogdu F,Bektas M,Bayirli DT,Serefhanoglu K

更新日期：2020-11-01 00:00:00

abstract：:Unlike other parts of the world in which cardiomyopathy is rare, heart muscle disease is endemic in Africa. The major forms of cardiomyopathy in Africa are dilated cardiomyopathy (DCM) and endomyocardial fibrosis (EMF). Whereas DCM is a major cause of heart failure throughout the continent, EMF is restricted to the tr...

journal_title：Cardiovascular journal of Africa

authors： Mayosi BM,Somers K

更新日期：2007-05-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the effects of the sphingosine analogue, FTY720 (Fingolimod), on the outcomes of myocardial ischaemia/reperfusion (I/R) injury. METHODS:Two concentrations of FTY720 (1 or 2.5 µM were administered either prior to (PreFTY), or following (PostFTY) 20 minutes' global (GI) or 35 mi...

journal_title：Cardiovascular journal of Africa

authors： van Vuuren D,Marais E,Genade S,Lochner A

更新日期：2016-11-01 00:00:00

abstract：INTRODUCTION:The functional significance of coronary artery collateral (CAC) vasculature in humans has been debated for decades and this has been compounded by the lack of a standard, systematic, objective method of grading and documenting CAC flow in man. CACs serve as alternative conduits for blood in obstructive cor...

journal_title：Cardiovascular journal of Africa

authors： Ajayi NO,Vanker EA,Satyapal KS

更新日期：2017-03-01 00:00:00

abstract：:Angiogenic imbalance contributes to the development of preeclampsia. We evaluated the protein expression of the proangiogenic placental growth factor (PlGF) and transforming growth factor beta 1 (TGF-β1) compared with the anti-angiogenic soluble fms-like tyrosine kinase receptor (sFlt1) and soluble endoglin (sEng) in ...

journal_title：Cardiovascular journal of Africa

authors： Govender N,Naicker T,Moodley J

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To identify case fatality rates and predictors of stroke in a private clinic in Kinshasa, Democratic Republic of Congo. METHODS:Two hundred and twelve black Africans were consecutively admitted to a clinic and prospectively assessed during the first 30 days by CT scan-proven stroke types and outcome. Univari...

journal_title：Cardiovascular journal of Africa

authors： Longo-Mbenza B,Lelo Tshinkwela M,Mbuilu Pukuta J

更新日期：2008-03-01 00:00:00

abstract：:An established relationship exists between human immunodeficiency virus (HIV) and the vascular system, which is characterised by clinical expressions of aneurysmal and occlusive disease that emanate from a common pathological process. The exact pathogenesis is currently unknown; attempts to implicate opportunistic pat...

journal_title：Cardiovascular journal of Africa

authors： Pillay B,Ramdial PK,Naidoo DP

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:A coronary artery anomaly precludes the use of a trans-annular patch in right ventricular outflow tract (RVOT) reconstruction. Herein we present three patients with coronary artery anomalies who underwent total corrective operations without using a conduit. METHODS:Between 2007 and 2010, 84 patients with ...

journal_title：Cardiovascular journal of Africa

authors： Saritas B,Ozker E,Vuran E,Yoruker U,Ayabakan C,Turkoz R

更新日期：2012-03-12 00:00:00

abstract：BACKGROUND:A four-amino acid deletion was identified within the alpha 2C-adrenergic receptor (alpha 2C Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the alpha 2C Del322-325 polymorphism may be a risk factor for heart fa...

journal_title：Cardiovascular journal of Africa

authors： Du Preez J,Matolweni LO,Greenberg J,Mntla P,Adeyemo AA,Mayosi BM

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) has been the leading cause of death in developed countries for most of the last century. Most CVD deaths, however, occur in low- and middle-income, developing countries (LMICs) and there is great concern that CVD mortality and burden are rapidly increasing in LMICs as a result of...

journal_title：Cardiovascular journal of Africa

authors： Mensah GA,Roth GA,Sampson UK,Moran AE,Feigin VL,Forouzanfar MH,Naghavi M,Murray CJ,GBD 2013 Mortality and Causes of Death Collaborators.

更新日期：2015-03-01 00:00:00

abstract：:Cardiovascular conditions associated with pregnancy are serious complications. In general, depression is a well-known risk indicator for cardiovascular disease (CVD). Mental distress and depression are associated with physiological responses such as inflammation and oxidative stress. Both inflammation and oxidative st...

journal_title：Cardiovascular journal of Africa

authors： Nicholson L,Lecour S,Wedegärtner S,Kindermann I,Böhm M,Sliwa K

更新日期：2016-03-01 00:00:00

abstract：AIM:There are few studies to be found in the literature on ankle-brachial index in sickle cell disease. The aim of this study was to compare ankle-brachial index of steadystate adult sickle cell anaemia patients with that of normal controls. METHODS:A descriptive cross-sectional study of 62 sickle cell anaemia patient...

journal_title：Cardiovascular journal of Africa

authors： Oguanobi NI,Onwubere BJ,Ibegbulam OG,Ike SO,Ejim EC,Agwu O

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality. In the current prospective study, we addressed the impact of RA on left atrial (LA) function and electrical remodelling. Further, we tried to demonstrate the effects of infliximab, an anti-TNF-alpha agent, on echoc...

journal_title：Cardiovascular journal of Africa

authors： Çetin S,Mustafa G,Keskin G,Yeter E,Doğan M,Öztürk MA

更新日期：2014-07-01 00:00:00

abstract：:This review discusses the 1987 article by Wyndham, Seftel, Pilcher and Baker on familial hypercholesterolaemia (FH) and myocardial infarction (MI) in young Afrikaners, in terms of the significance at the time of publication, as well as the relevance of their findings versus current observations on hypercholesterolaemi...

journal_title：Cardiovascular journal of Africa

authors： Delport R

更新日期：2009-01-01 00:00:00

abstract：:In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, further complicated by limited therapeutic options and inconsistent follow up. The consequences are ...

journal_title：Cardiovascular journal of Africa

authors： Meyer PW,Anderson R,Ker JA,Ally MT

更新日期：2018-09-01 00:00:00

abstract：:Very late bare-metal stent (BMS) thrombosis is unusual in clinical practice. To the best of our knowledge, the latest that the thrombosis of a BMS has been reported is 14 years after implantation. Here, we describe a case of BMS thrombosis that occurred two decades after stenting. A 68-year-old male patient was admitt...

journal_title：Cardiovascular journal of Africa

authors： Acibuca A,Gerede DM,Vurgun VK

更新日期：2015-07-23 00:00:00