An evaluation of ankle-brachial blood pressure index in adult Nigerians with sickle cell anaemia.

Abstract:

AIM:There are few studies to be found in the literature on ankle-brachial index in sickle cell disease. The aim of this study was to compare ankle-brachial index of steadystate adult sickle cell anaemia patients with that of normal controls. METHODS:A descriptive cross-sectional study of 62 sickle cell anaemia patients and 62 age- and gender-matched normal controls was carried out in the adult outpatient sickle cell clinics and the cardiac centre of the University of Nigeria Teaching Hospital (UNTH), Enugu, Nigeria from February to August 2007. The supine brachial and ankle blood pressures were measured separately with the cuff of the mercury sphygmomanometer applied to the right arm and right calf, respectively. RESULTS:The ankle systolic blood pressure was lower in patients with sickle cell anaemia than in the controls (p < 0.001). The mean indices for ankle-brachial index were 0.88 ± 0.09 and 1.03 ± 0.06, respectively for patients and controls. This difference was statistically significant (p < 0.001). Seventy three per cent of the patients had ankle-brachial index less than 0.9 compared with controls (5%). This was also significant (p < 0.001).

journal_name

Cardiovasc J Afr

authors

Oguanobi NI,Onwubere BJ,Ibegbulam OG,Ike SO,Ejim EC,Agwu O

doi

10.5830/CVJA-2011-013

subject

Has Abstract

pub_date

2012-02-01 00:00:00

pages

37-9

issue

1

eissn

1995-1892

issn

1680-0745

journal_volume

23

pub_type

杂志文章
  • The effect of mebudipine on cardiac function and activity of the myocardial nitric oxide system in ischaemia-reperfusion injury in rats.

    abstract:OBJECTIVES:Previous studies have suggested that failure of the synthesis of nitric oxide is involved in the pathophysiology of myocardial ischaemia-reperfusion injury. In this study, we investigated the effect of mebudipine, a new dihydropyridine calcium channel blocker, on cardiac function and activity of the myocardi...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2010-078

    authors: Ghyasi R,Mohammadi M,Badalzadeh R,Rashidi B,Sepehri G

    更新日期:2011-11-01 00:00:00

  • The clinical prognostic significance of myocardial performance index (MPI) in stable placental-mediated disease.

    abstract:AIM:To determine whether a single elevated myocardial performance index (MPI) value in the third trimester of pregnancy is a marker for later adverse obstetric outcomes in stable placental-mediated disease, defined as well-controlled pre-eclampsia (PE) on a single agent and/or uncompensated intra-uterine growth restric...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2018-036

    authors: Bhorat I,Pillay M,Reddy T

    更新日期:2018-09-01 00:00:00

  • Familial hypercholesterolaemia in South Africans: tracking findings and developments over time - with reference to : prevalence of hypercholesterolaemia in young Afrikaners with myocardial infarction. Ischaemic heart disease risk factors.

    abstract::This review discusses the 1987 article by Wyndham, Seftel, Pilcher and Baker on familial hypercholesterolaemia (FH) and myocardial infarction (MI) in young Afrikaners, in terms of the significance at the time of publication, as well as the relevance of their findings versus current observations on hypercholesterolaemi...

    journal_title:Cardiovascular journal of Africa

    pub_type: 历史文章,杂志文章

    doi:

    authors: Delport R

    更新日期:2009-01-01 00:00:00

  • Rates and predictors of stroke-associated case fatality in black Central African patients.

    abstract:OBJECTIVE:To identify case fatality rates and predictors of stroke in a private clinic in Kinshasa, Democratic Republic of Congo. METHODS:Two hundred and twelve black Africans were consecutively admitted to a clinic and prospectively assessed during the first 30 days by CT scan-proven stroke types and outcome. Univari...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:

    authors: Longo-Mbenza B,Lelo Tshinkwela M,Mbuilu Pukuta J

    更新日期:2008-03-01 00:00:00

  • Resection of left anterior descending coronary artery aneurysm on a beating heart.

    abstract::We report on the case of a 65-year-old man with unstable angina due to a left anterior descending (LAD) coronary artery single aneurysm. On a beating heart, the aneurysm was partially resected and the left internal thoracic artery was grafted in situ as a patch to the LAD opening. The patient remains well and free of ...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:

    authors: Misthos P,Kokotsakis JN,Lioulias AG,Skouteli EA

    更新日期:2009-03-01 00:00:00

  • Performance of re-used pacemakers and implantable cardioverter defibrillators compared with new devices at Groote Schuur Hospital in Cape Town, South Africa.

    abstract:OBJECTIVES:Little is known about the performance of re-used pacemakers and implantable cardioverter defibrillators (ICDs) in Africa. We sought to compare the risk of infection and the rate of malfunction of re-used pacemakers and ICDs with new devices implanted at Groote Schuur Hospital in Cape Town, South Africa. MET...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2015-048

    authors: Jama ZV,Chin A,Badri M,Mayosi BM

    更新日期:2015-07-01 00:00:00

  • Audit of availability and distribution of paediatric cardiology services and facilities in Nigeria.

    abstract:BACKGROUND:Paediatric cardiac services in Nigeria have been perceived to be inadequate but no formal documentation of availability and distribution of facilities and services has been done. OBJECTIVE:To evaluate and document the currently available paediatric cardiac services in Nigeria. METHODS:In this questionnaire...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章,多中心研究

    doi:10.5830/CVJA-2016-057

    authors: Ekure EN,Sadoh WE,Bode-Thomas F,Orogade AA,Animasahun AB,Ogunkunle OO,Babaniyi I,Anah MU,Otaigbe BE,Olowu A,Okpokowuruk F,Omokhodion SI,Maduka OC,Onakpoya UU,Adiele DK,Sani UM,Asani M,Yilgwan CS,Daniels Q,Uzodimma C

    更新日期:2017-01-01 00:00:00

  • p53 negatively regulates the osteogenic differentiation of vascular smooth muscle cells in mice with chronic kidney disease.

    abstract:AIM:To investigate the osteogenic differentiation of vascular smooth muscle cells (VSMCs) in mice with chronic kidney disease (CKD) and to evaluate the effects of p53 on the osteogenic differentiation of the VSMCs. METHODS:Experimental models of CKD-associated vascular calcification generated by five-sixth (5/6) nephr...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2011-069

    authors: Li KL,Chen J,Li ZH,Zhao L,He YN

    更新日期:2012-07-12 00:00:00

  • AMP kinase activation and glut4 translocation in isolated cardiomyocytes.

    abstract::Activation of AMP-activated protein kinase (AMPK) results in glucose transporter 4 (GLUT4) translocation from the cytosol to the cell membrane, and glucose uptake in the skeletal muscles. This increased activation of AMPK can be stimulated by a pharmacological agent, AICAR (5' -aminoimidazole-4-carboxamide ribonucleos...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:

    authors: Webster I,Friedrich SO,Lochner A,Huisamen B

    更新日期:2010-03-01 00:00:00

  • The influence of diabetes on short-term outcome following a prosthetic above-the-knee femoro-popliteal bypass.

    abstract:OBJECTIVES:To assess the influence of diabetes mellitus on early morbidity and mortality following a femoro-popliteal bypass. METHODS:Clinical data on patients subjected to a prosthetic above-the-knee femoro-popliteal bypass for atherothrombotic disease over a four-year period in the Durban Metropolitan Vascular Servi...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:

    authors: Mulaudzi TV,Robbs JV,Paruk N,Pillay B,Madiba TE,Govindsamy V

    更新日期:2009-05-01 00:00:00

  • Atherosclerotic disease is the predominant aetiology of acute coronary syndrome in young adults.

    abstract:OBJECTIVES:Few studies have evaluated young adults in their third and fourth decades with coronary artery disease (CAD). This study evaluated the clinical and angiographic profile of young adults ( < 35 years) with CAD. METHODS:A 10-year (2003-2012) retrospective chart review was performed on patients less than 35 yea...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2017-035

    authors: Pillay AK,Naidoo DP

    更新日期:2018-01-01 00:00:00

  • The history of the Pan-African Society of Cardiology (PASCAR): the first 30 years, 1981-2011.

    abstract::The year 2011 marks the 30th anniversary of the founding of the Pan-African Society of Cardiology (PASCAR). Throughout its brief history, PASCAR has been integral to improving the cardiovascular health of the people of Africa. During the past three decades, many African countries have been vulnerable to political and ...

    journal_title:Cardiovascular journal of Africa

    pub_type: 社论,历史文章

    doi:

    authors: Watkins D,Omokhodion SI,Mayosi BM

    更新日期:2011-05-01 00:00:00

  • The effect of lifestyle interventions on maternal body composition during pregnancy in developing countries: a systematic review.

    abstract::Optimal maternal body composition during pregnancy is a public health priority due to its implications on maternal health and infant development. We therefore aimed to conduct a systematic review of randomised, controlled trials, and case-control and cohort studies using lifestyle interventions to improve body composi...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章,评审

    doi:10.5830/CVJA-2017-003

    authors: Watson ED,Macaulay S,Lamont K,Gradidge PJ,Pretorius S,Crowther NJ,Libhaber E

    更新日期:2017-11-01 00:00:00

  • Presenting features of newly diagnosed rheumatic heart disease patients in Mulago Hospital: a pilot study.

    abstract:INTRODUCTION:Rheumatic heart disease (RHD) continues to cause gross distortions of the heart and the associated complications of heart failure and thromboembolic phenomena in this age of numerous high-efficacy drugs and therapeutic interventions. Due to the lack of contemporary local data, there is no national strategy...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2012-076

    authors: Zhang W,Mondo C,Okello E,Musoke C,Kakande B,Nyakoojo W,Kayima J,Freers J

    更新日期:2013-03-01 00:00:00

  • Neonatal circulatory failure due to acute hypertensive crisis: clinical and echocardiographic clues.

    abstract:OBJECTIVE:Circulatory failure due to acute arterial hypertension in the neonatal period is rare. This study was undertaken to assess the clinical and echocardiographic manifestations of circulatory failure resulting from acute neonatal hypertensive crisis. METHODS:Neonatal and cardiology databases from 2007 to 2010 we...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2013-003

    authors: Louw J,Brown S,Thewissen L,Smits A,Eyskens B,Heying R,Cools B,Levtchenko E,Allegaert K,Gewillig M

    更新日期:2013-04-01 00:00:00

  • Acquired von Willebrand syndrome in children with aortic and pulmonary stenosis.

    abstract:INTRODUCTION:This prospective study was planned to investigate the frequency and relationship of acquired von Willebrand syndrome (AVWS) with aortic and pulmonary stenosis in patients. METHODS:A total of 84 children, ranging from two to 18 years of age, were enrolled in this study. Of these, 28 had isolated aortic ste...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2015-093

    authors: Binnetoğlu FK,Babaoğlu K,Filiz ŞG,Zengin E,Altun G,Kılıç SÇ,Sarper N

    更新日期:2016-07-01 00:00:00

  • Achieving blood preSsure goals sTudy in uncontrolled hypeRtensive pAtients treated with a fixed-dose combination of ramipriL/hydrochlorothiazide: the ASTRAL study.

    abstract:BACKGROUND:Hypertension is a common cardiovascular disease, affecting adults worldwide and it accounts for up to 30% of all deaths. The need for better control of arterial hypertension justifies observational studies designed to better understand the real-life management of hypertensive patients. The ASTRAL study was p...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章,多中心研究

    doi:10.5830/cvja-2010-086

    authors: Okpechi IG,Schoeman HS,Longo-Mbenza B,Oke DA,Kingue S,Nkoua JL,Rayner BL

    更新日期:2011-03-01 00:00:00

  • Quality of life-associated factors among patients undergoing coronary artery bypass surgery as measured using the WHOQOL-BREF.

    abstract::This was a study of the pre-operative factors that influence quality of life (QoL) in patients with coronary artery disease and the relationship between pre-operative QoL and early outcome after coronary artery bypass surgery (CABG). Using the WHOQOL-BREF questionnaire, 283 patients who underwent isolated coronary art...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:

    authors: Najafi M,Sheikhvatan M,Montazeri A

    更新日期:2009-09-01 00:00:00

  • Acute aortic dissection with a dangerous duo in an adolescent boy.

    abstract::Acute type II aortic dissection and aortic coarctation are rare combined disorders. This report is of a patient with coarctation, a bicuspid aortic valve and type II dissection, who underwent emergency repair for the dissection, with aortic valve preservation. Repair of the coarctation was planned for a future occasio...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2013-064

    authors: Bezgin T,Doğan C,Elveran A,Karagöz A,Yücel C,Esen AM

    更新日期:2013-09-23 00:00:00

  • The variability of baroreflex sensitivity in juvenile, spontaneously hypertensive rats.

    abstract::In this study the baroreflex sensitivity of conscious, juvenile, spontaneously hypertensive rats (SHRs) was compared. The study population consisted of 19 eight-week-old male SHRs. The baroreflex sensitivity was quantified as the derivative of the variation in heart rate (HR) and the variation of mean arterial pressur...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/cvja-2010-007

    authors: Valenti VE,De Abreu LC,Colombari E,Sato MA,Ferreira C

    更新日期:2011-01-01 00:00:00

  • The dangerous fifth chamber: congenital left atrial appendage aneurysm.

    abstract::Aneurysms of the left atrial appendage are extremely rare. Enlargement of the left atrial appendage can be congenital or acquired. Dysplasia of the left atrial muscles leads to congenital left atrial appendage aneurysm and usually presents as atrial tachyarrhythmia or embolic events in the second or third decade of li...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2011-051

    authors: Tigen KM,Dogan C,Guler A,Hatipoglu S,Yanartas M,Kirma C

    更新日期:2012-06-12 00:00:00

  • Behcet's disease and cardiovascular involvement: our experience of asymptomatic Behcet's patients.

    abstract::Behcet's syndrome is a systemic inflammatory disease associated with vasculitis, and arterial, venous and cardiac disorders. Thirty-eight Behcet's disease patients were examined prospectively with echocardiography, ultrasonography and computed tomography, and coagulation parameters were determined. Deep venous insuffi...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2014-003

    authors: Ulusan Z,Karadag AS,Tasar M,Kalender M,Darcin OT

    更新日期:2014-03-01 00:00:00

  • Transcatheter closure of the patent ductus arteriosus at a public sector hospital in Soweto, South Africa: a review of patient outcomes over 15 years.

    abstract:BACKGROUND:Methods of closing patent ductus arteriosus (PDA) have evolved over time. We review this development in our setting. METHODS:This was a retrospective analysis of children who had transcatheter PDA closure at Chris Hani Baragwanath Hospital between 1993 and 2008. RESULTS:Over 15 years, 1 254 PDAs were diagn...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2018-028

    authors: Adams PE,Chersich MF,Cilliers A

    更新日期:2018-07-01 00:00:00

  • The differential effects of FTY720 on functional recovery and infarct size following myocardial ischaemia/reperfusion.

    abstract:AIM:The aim of this study was to evaluate the effects of the sphingosine analogue, FTY720 (Fingolimod), on the outcomes of myocardial ischaemia/reperfusion (I/R) injury. METHODS:Two concentrations of FTY720 (1 or 2.5 µM were administered either prior to (PreFTY), or following (PostFTY) 20 minutes' global (GI) or 35 mi...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2016-039

    authors: van Vuuren D,Marais E,Genade S,Lochner A

    更新日期:2016-11-01 00:00:00

  • Repetitive use of levosimendan in clinical practice: a case series.

    abstract::Levosimendan was developed as a treatment for acute decompensation of severe heart failure (HF). Its use has evolved during recent years, and new HF treatment strategies in different settings have been developed. This case series aimed to show indications for the use of levosimendan and to discuss the treatment respon...

    journal_title:Cardiovascular journal of Africa

    pub_type:

    doi:10.5830/CVJA-2020-058

    authors: Wawrzyniak M,Migaj J,Straburzyńska-Migaj E,Dudek M,Kałużna-Oleksy M

    更新日期:2021-01-15 00:00:00

  • Vascular health assessment with flow-mediated dilatation and retinal image analysis: a pilot study in an adult population from Cape Town.

    abstract:AIM:Flow-mediated dilatation (FMD) and retinal vascular analysis (RVA) may assist in predicting cardiovascular disease (CVD) but are poorly characterised in South Africa. We recorded baseline FMD and retinal vascular widths in healthy participants, and investigated associations with cardiovascular risk factors. METHOD...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2020-046

    authors: Marincowitz C,Webster I,Westcott C,Goswami N,de Boever P,Seidel G,Strijdom H

    更新日期:2020-11-13 00:00:00

  • Surgical management of effusive constrictive pericarditis.

    abstract:OBJECTIVE:The surgical approach for effusive constrictive pericarditis (ECP) has not been extensively studied. We present our institution's early and long-term results of pericardiectomy in our cohort of patients with ECP. METHODS:Diagnosis was made primarily by echocardiography. Right heart catheterisation was perfor...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2013-042

    authors: Buyukbayrak F,Aksoy E,Tas S,Kirali K

    更新日期:2013-09-01 00:00:00

  • The value of community outreach for a University: a synthesis of trends in higher education The case of the University of Limpopo (ELS 45).

    abstract:BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:10.5830/CVJA-2018-059

    authors: Siweya H,Monyeki KD

    更新日期:2019-01-01 00:00:00

  • The hyperparathyroid heart mimicking acute myocardial infarction.

    abstract::Left ventricular hypertrophy is a common complication of primary hyperparathyroidism. Numerous disturbances of myocardial physiology have been described as a result of excess parathyroid hormone action. In this brief communication, another phenotype of the hyperparathyroid heart is proposed, the 'pseudo-myocardial inf...

    journal_title:Cardiovascular journal of Africa

    pub_type: 杂志文章

    doi:

    authors: Ker J

    更新日期:2009-05-01 00:00:00

  • Coronavirus disease 2019 (COVID-19) and simultaneous acute anteroseptal and inferior ST-segment elevation myocardial infarction.

    abstract::Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...

    journal_title:Cardiovascular journal of Africa

    pub_type:

    doi:10.5830-CVJA-2020-016

    authors: Yolcu M,Gunesdogdu F,Bektas M,Bayirli DT,Serefhanoglu K

    更新日期:2020-11-01 00:00:00