Vascular health assessment with flow-mediated dilatation and retinal image analysis: a pilot study in an adult population from Cape Town.

abstract：AIM:To determine whether a single elevated myocardial performance index (MPI) value in the third trimester of pregnancy is a marker for later adverse obstetric outcomes in stable placental-mediated disease, defined as well-controlled pre-eclampsia (PE) on a single agent and/or uncompensated intra-uterine growth restric...

journal_title：Cardiovascular journal of Africa

authors： Bhorat I,Pillay M,Reddy T

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:Cardiac resynchronisation therapy has been shown to be an effective treatment to improve functional status and prolong survival of patients in advanced chronic heart failure. This study assessed the surgical outcomes of left anterior mini-thoracotomy for the implantation of left ventricular epicardial pacing ...

journal_title：Cardiovascular journal of Africa

authors： Ezelsoy M,Bayram M,Yazici S,Yazicioglu N,Sagbas E

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Left atrial remodelling (LAR) has been described in Western populations with chronic hypertension and is associated with a higher risk of adverse cardiovascular events. Although hypertension tends to occur earlier and is more severe in sub-Saharan Africa than in more developed nations, LAR and its associated...

journal_title：Cardiovascular journal of Africa

authors： Gounoue AC,Tamdja AD,Choukem SP,Ba H,Aboubakar SM,Nzali A,Halle MP,Nkoke C,Kadia BM,Abanda MH,Nganou CN,Abzabji MK,Kingue S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) has been the leading cause of death in developed countries for most of the last century. Most CVD deaths, however, occur in low- and middle-income, developing countries (LMICs) and there is great concern that CVD mortality and burden are rapidly increasing in LMICs as a result of...

journal_title：Cardiovascular journal of Africa

authors： Mensah GA,Roth GA,Sampson UK,Moran AE,Feigin VL,Forouzanfar MH,Naghavi M,Murray CJ,GBD 2013 Mortality and Causes of Death Collaborators.

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality. In the current prospective study, we addressed the impact of RA on left atrial (LA) function and electrical remodelling. Further, we tried to demonstrate the effects of infliximab, an anti-TNF-alpha agent, on echoc...

journal_title：Cardiovascular journal of Africa

authors： Çetin S,Mustafa G,Keskin G,Yeter E,Doğan M,Öztürk MA

更新日期：2014-07-01 00:00:00

abstract：:We researched hypertrophic cardiomyopathy (HCM) and long QT syndrome (LQTS) as models for studying the pathophysiology of arrhythmias and hypertrophy, and in the process we have had the opportunity to compare local disease profiles with global patterns. We trawled our database entries over the past 20 years to identif...

journal_title：Cardiovascular journal of Africa

authors： Heradien M,Goosen A,Moolman-Smook JC,Brink PA

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:Few data are available on heart failure (HF) in sub-Saharan Africa. We aimed to provide a current picture of HF aetiologies in urban Uganda, access to heart surgery, and outcomes. METHODS:We prospectively collected clinical and echocardiographic data from 272 consecutive patients referred for suspected heart...

journal_title：Cardiovascular journal of Africa

authors： Grimaldi A,Ammirati E,Karam N,Vermi AC,de Concilio A,Trucco G,Aloi F,Arioli F,Figini F,Ferrarello S,Sacco FM,Grottola R,D'Arbela PG,Alfieri O,Marijon E,Freers J,Mirabel M

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to report on our experience with upper limb ischaemia (ULI), to define the pattern and distribution of disease, describe key demographic features and report on conventional clinical outcomes. METHODS:This was a single-centre, retrospective, descriptive study. All patients (n = 64)...

journal_title：Cardiovascular journal of Africa

authors： du Toit T,Manning K,Naidoo NG

更新日期：2018-03-01 00:00:00

abstract：:We present a case of the native valve used to complete closure of a ruptured aneurysm of the sinus of Valsalva. Aneurysm of the sinus of Valsalva is rare and a non-coronary artery is affected in only 20% of cases. To close the rupture, we decided to use a non-coronary leaflet in a young patient with moderate aortic st...

journal_title：Cardiovascular journal of Africa

authors： Buczkowski P,Walczak M,Stefaniak S,Puślecki M,Katyńska I,Jemielity M

更新日期：2014-08-23 00:00:00

abstract：AIM:Our aim was to evaluate whether there was a relationship between mean platelet volume and myocardial perfusion defect in diabetic patients using myocardial perfusion imaging. METHODS:Forty-four diabetic patients with myocardial perfusion defect (group 1) and 44 diabetic patients without myocardial perfusion defect...

journal_title：Cardiovascular journal of Africa

authors： Sarikaya S,Sahin S,Akyol L,Borekci E,Yilmaz YK,Altunkas F,Karaman K,Karacavus S,Erbay AR

更新日期：2014-05-01 00:00:00

abstract：:Left ventricular hypertrophy is a common complication of primary hyperparathyroidism. Numerous disturbances of myocardial physiology have been described as a result of excess parathyroid hormone action. In this brief communication, another phenotype of the hyperparathyroid heart is proposed, the 'pseudo-myocardial inf...

journal_title：Cardiovascular journal of Africa

authors： Ker J

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To document maternal and foetal morbidity and mortality in anticoagulated, pregnant patients with mechanical heart valves until 42 days postpartum. METHODS:In a tertiary single-centre, prospective cohort, 178 consecutive patients at the cardiac-obstetric clinic were screened for warfarin use between 1 July 2...

journal_title：Cardiovascular journal of Africa

authors： Kariv S,Azibani F,Baard J,Osman A,Soma-Pillay P,Anthony J,Sliwa K

更新日期：2018-09-01 00:00:00

abstract：:Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocard...

journal_title：Cardiovascular journal of Africa

authors： McCutcheon K,Manga P

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Cardiac complications of human immunodeficiency virus (HIV) infection are important causes of morbidity and mortality. We set out to determine the electrocardiographic (ECG) abnormalities in treatment-naïve HIV-positive patients in Enugu, south-east Nigeria. METHODS:This was a cross-sectional study involvin...

journal_title：Cardiovascular journal of Africa

authors： Okoye IC,Anyabolu EN

更新日期：2017-09-01 00:00:00

abstract：:Acute aortic dissection is a life-threatening disease that requires immediate surgical intervention. Although aortic dissection is a rare condition during pregnancy, it is of high risk for both mother and foetus. Most cases of aortic dissection during pregnancy have certain risk factors, including Marfan syndrome and ...

journal_title：Cardiovascular journal of Africa

authors： Simsek Y,Colak C,Yilmaz E,Celik E,Erdil N,Celik O

更新日期：2012-11-23 00:00:00

abstract：:Behcet's syndrome is a systemic inflammatory disease associated with vasculitis, and arterial, venous and cardiac disorders. Thirty-eight Behcet's disease patients were examined prospectively with echocardiography, ultrasonography and computed tomography, and coagulation parameters were determined. Deep venous insuffi...

journal_title：Cardiovascular journal of Africa

authors： Ulusan Z,Karadag AS,Tasar M,Kalender M,Darcin OT

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:Previous studies have suggested that failure of the synthesis of nitric oxide is involved in the pathophysiology of myocardial ischaemia-reperfusion injury. In this study, we investigated the effect of mebudipine, a new dihydropyridine calcium channel blocker, on cardiac function and activity of the myocardi...

journal_title：Cardiovascular journal of Africa

authors： Ghyasi R,Mohammadi M,Badalzadeh R,Rashidi B,Sepehri G

更新日期：2011-11-01 00:00:00

abstract：:Peripheral arterial disease (PAD) represents a major public health problem due to its high and increasing prevalence, worldwide distribution, and significant morbidity and mortality rate. Female gender is a risk factor for PAD globally and especially in low-income countries. In this review, we summarise the present kn...

journal_title：Cardiovascular journal of Africa

authors： Comşa HI,Zdrenghea D,Man SC,Pop D

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:A four-amino acid deletion was identified within the alpha 2C-adrenergic receptor (alpha 2C Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the alpha 2C Del322-325 polymorphism may be a risk factor for heart fa...

journal_title：Cardiovascular journal of Africa

authors： Du Preez J,Matolweni LO,Greenberg J,Mntla P,Adeyemo AA,Mayosi BM

更新日期：2008-01-01 00:00:00

abstract：:We present images of a chest CT scan of an 89-year-old man, showing an area of localised dissection in the convexity of the aortic arch. The ascending and descending aorta were not involved in the disease. The patient suffered a stroke, with severe neurological impairment. Differential diagnosis was undertaken. ...

journal_title：Cardiovascular journal of Africa

authors： Lentini S,Passari G,David A,Gaeta R

更新日期：2009-11-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...

journal_title：Cardiovascular journal of Africa

authors： Yolcu M,Gunesdogdu F,Bektas M,Bayirli DT,Serefhanoglu K

更新日期：2020-11-01 00:00:00

abstract：AIM:There are few studies to be found in the literature on ankle-brachial index in sickle cell disease. The aim of this study was to compare ankle-brachial index of steadystate adult sickle cell anaemia patients with that of normal controls. METHODS:A descriptive cross-sectional study of 62 sickle cell anaemia patient...

journal_title：Cardiovascular journal of Africa

authors： Oguanobi NI,Onwubere BJ,Ibegbulam OG,Ike SO,Ejim EC,Agwu O

更新日期：2012-02-01 00:00:00

abstract：:Activation of AMP-activated protein kinase (AMPK) results in glucose transporter 4 (GLUT4) translocation from the cytosol to the cell membrane, and glucose uptake in the skeletal muscles. This increased activation of AMPK can be stimulated by a pharmacological agent, AICAR (5' -aminoimidazole-4-carboxamide ribonucleos...

journal_title：Cardiovascular journal of Africa

authors： Webster I,Friedrich SO,Lochner A,Huisamen B

更新日期：2010-03-01 00:00:00

abstract：INTRODUCTION:This prospective study was planned to investigate the frequency and relationship of acquired von Willebrand syndrome (AVWS) with aortic and pulmonary stenosis in patients. METHODS:A total of 84 children, ranging from two to 18 years of age, were enrolled in this study. Of these, 28 had isolated aortic ste...

journal_title：Cardiovascular journal of Africa

authors： Binnetoğlu FK,Babaoğlu K,Filiz ŞG,Zengin E,Altun G,Kılıç SÇ,Sarper N

更新日期：2016-07-01 00:00:00

abstract：:We are deeply saddened by the loss of our great teacher Donald Ross, a truly global mentor in cardiac surgery, a friend, a respectful colleague, an admirer, and custodian of our profession, who passed away on July 7, 2014. ...

journal_title：Cardiovascular journal of Africa

authors： Yankah C

更新日期：2014-07-01 00:00:00

abstract：:Optimal maternal body composition during pregnancy is a public health priority due to its implications on maternal health and infant development. We therefore aimed to conduct a systematic review of randomised, controlled trials, and case-control and cohort studies using lifestyle interventions to improve body composi...

journal_title：Cardiovascular journal of Africa

authors： Watson ED,Macaulay S,Lamont K,Gradidge PJ,Pretorius S,Crowther NJ,Libhaber E

更新日期：2017-11-01 00:00:00

abstract：:Hypertension is more prevalent and severe in urban black populations compared to whites, and is associated with a greater degree of target-organ damage for any given blood pressure level. In general, compared to whites, blacks respond well to diuretics and calcium channel blockers and less well to beta-blockers and AC...

journal_title：Cardiovascular journal of Africa

authors： Lindhorst J,Alexander N,Blignaut J,Rayner B

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To identify socio-demographic and lifestyle determinants of weight gain in a sample of premenopasual black South African (SA) women. METHODS:Changes in body composition (dual-energy X-ray absorptiometry, computerised tomography), socio-economic status (SES) and behavioural/lifestyle factors were measured in ...

journal_title：Cardiovascular journal of Africa

authors： Chantler S,Dickie K,Micklesfield LK,Goedecke JH

更新日期：2016-11-01 00:00:00

abstract：:Resistant hypertension is a common clinical problem in South Africa and is frequently associated with low renin and aldosterone levels, especially in black Africans. In South Africa, novel variants in the epithelial sodium channel (ENaC) have been described to be associated with varying degrees of hypokalaemia and hyp...

journal_title：Cardiovascular journal of Africa

authors： Freercks R,Meldau S,Jones E,Ensor J,Weimers-Willard C,Rayner B

更新日期：2017-09-23 00:00:00

abstract：BACKGROUND:Guidelines advise early angiography in non-ST elevation myocardial infarction (NSTEMI) to ensure an optimal outcome. Resource limitations in secondary hospitals in the Western Cape dictate a local guideline to treat NSTEMIs medically with out-patient assessment for angiography, unless mandatory indications f...

journal_title：Cardiovascular journal of Africa

authors： Moses J,Doubell AF,Herbst PG,Klusmann KJ,Weich HS

更新日期：2013-05-01 00:00:00