Mean platelet volume is associated with myocardial perfusion defect in diabetic patients.

Abstract:

AIM:Our aim was to evaluate whether there was a relationship between mean platelet volume and myocardial perfusion defect in diabetic patients using myocardial perfusion imaging. METHODS:Forty-four diabetic patients with myocardial perfusion defect (group 1) and 44 diabetic patients without myocardial perfusion defect (group 2), matched for age and gender, were retrospectively examined. Levels of mean platelet volume (MPV) in the two groups were assessed. RESULTS:MPV was higher in group 1 than group 2 patients (8.76 ± 0.76 and 8.25 ± 0.78 fl), respectively, p = 0.003). Levels of glucose, triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, haemoglobin (Hb) and glycosylated haemoglobin (HbA1c), and body mass index (BMI) in the two groups were not statistically significantly different. Multivariate logistic regression analyses showed that MPV was the only variable independently associated with myocardial perfusion defects (OR: 2.401, 95% CI: 1.298-4.440, p = 0.013). CONCLUSION:This study showed that higher MPV was associated with myocardial perfusion defects. Higher MPV in diabetic patients was independently related to myocardial perfusion defects and may be an indicator of myocardial ischaemia.

journal_name

Cardiovasc J Afr

authors

Sarikaya S,Sahin S,Akyol L,Borekci E,Yilmaz YK,Altunkas F,Karaman K,Karacavus S,Erbay AR

doi

10.5830/CVJA-2014-013

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

110-3

issue

3

eissn

1995-1892

issn

1680-0745

journal_volume

25

pub_type

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