AMP kinase activation and glut4 translocation in isolated cardiomyocytes.

abstract：AIM:Although plasma NT-proBNP differentiates hypertension (HT) with or without left ventricular hypertrophy (LVH) from hypertensive heart failure (HHF), most of the published data are based on studies in Western populations. Also, most previous studies did not consider left ventricular (LV) diastolic function and right...

journal_title：Cardiovascular journal of Africa

authors： Ojji DB,Opie LH,Lecour S,Lacerda L,Adeyemi OM,Sliwa K

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...

journal_title：Cardiovascular journal of Africa

authors： Siweya H,Monyeki KD

更新日期：2019-01-01 00:00:00

abstract：:This study examined the effects of quercetin on spontaneously contracting portal veins isolated from healthy young adult male and female Wistar rats (250-300 g). Quercetin (10(-7)-10(-4) M) always produced significant biphasic effects, comprising an initial brief stimulant effect (rise in basal tone), followed by a su...

journal_title：Cardiovascular journal of Africa

authors： Chiwororo WD,Ojewole JA

更新日期：2010-05-01 00:00:00

abstract：INTRODUCTION:The functional significance of coronary artery collateral (CAC) vasculature in humans has been debated for decades and this has been compounded by the lack of a standard, systematic, objective method of grading and documenting CAC flow in man. CACs serve as alternative conduits for blood in obstructive cor...

journal_title：Cardiovascular journal of Africa

authors： Ajayi NO,Vanker EA,Satyapal KS

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The surgical approach for effusive constrictive pericarditis (ECP) has not been extensively studied. We present our institution's early and long-term results of pericardiectomy in our cohort of patients with ECP. METHODS:Diagnosis was made primarily by echocardiography. Right heart catheterisation was perfor...

journal_title：Cardiovascular journal of Africa

authors： Buyukbayrak F,Aksoy E,Tas S,Kirali K

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality. In the current prospective study, we addressed the impact of RA on left atrial (LA) function and electrical remodelling. Further, we tried to demonstrate the effects of infliximab, an anti-TNF-alpha agent, on echoc...

journal_title：Cardiovascular journal of Africa

authors： Çetin S,Mustafa G,Keskin G,Yeter E,Doğan M,Öztürk MA

更新日期：2014-07-01 00:00:00

abstract：:Pulmonary hypertension (PH) has progressively moved from an orphan disease to a significant global health problem with a major disease burden in limited7hyphen;resource countries, where over 97% of patients live. The aetiologies of PH differ between high- and low-income nations, but PH due to left heart disease is cre...

journal_title：Cardiovascular journal of Africa

authors： Dzudie A,Kengne AP,Lamont K,Dzekem BS,Aminde LN,Abanda MH,Thienemann F,Sliwa K

更新日期：2019-01-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...

journal_title：Cardiovascular journal of Africa

authors： Yolcu M,Gunesdogdu F,Bektas M,Bayirli DT,Serefhanoglu K

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Dyslipidaemia is a major modifiable risk factor for atherosclerotic cardiovascular disease. At the time the study was conducted, guidelines recommended a low-density lipoprotein cholesterol (LDL-C) target of less than 1.8 mmol/l and a reduction of at least 50% if the baseline LDL-C was between 1.8 and 3.5 mm...

journal_title：Cardiovascular journal of Africa

authors： Blom DJ,Ranjith N,Joshi P,Naidoo P,van Tonder A,Musa MG,Joshi S,Leisegang R,Trokis JS,Makan H,Raal FJ

更新日期：2020-09-01 00:00:00

abstract：:A review of heart diseases in Africa shows that the cardiomyopathies continue to be important causes of morbidity and mortality in the population. Hypertension remains the commonest cause of myocardial disease, followed by the cardiomyopathies. Ischaemic heart disease continues to be rare. Of the cardiomyopathies, dil...

journal_title：Cardiovascular journal of Africa

authors： Falase AO,Ogah OS

更新日期：2012-11-01 00:00:00

abstract：:Type 2 diabetic patients treated with statins but still experiencing elevated serum levels of triglycerides (2.3 mmol/l or higher) and low HDL cholesterol (0.8 mmol/l or lower), a pre-specified subgroup, benefited from the addition of fenofibrate to their treatment regimen. Risk of cardiovascular events was reduced by...

journal_title：Cardiovascular journal of Africa

authors： Aalbers J

更新日期：2010-03-01 00:00:00

abstract：:Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocard...

journal_title：Cardiovascular journal of Africa

authors： McCutcheon K,Manga P

更新日期：2018-01-01 00:00:00

abstract：:The year 2011 marks the 30th anniversary of the founding of the Pan-African Society of Cardiology (PASCAR). Throughout its brief history, PASCAR has been integral to improving the cardiovascular health of the people of Africa. During the past three decades, many African countries have been vulnerable to political and ...

journal_title：Cardiovascular journal of Africa

authors： Watkins D,Omokhodion SI,Mayosi BM

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Left atrial remodelling (LAR) has been described in Western populations with chronic hypertension and is associated with a higher risk of adverse cardiovascular events. Although hypertension tends to occur earlier and is more severe in sub-Saharan Africa than in more developed nations, LAR and its associated...

journal_title：Cardiovascular journal of Africa

authors： Gounoue AC,Tamdja AD,Choukem SP,Ba H,Aboubakar SM,Nzali A,Halle MP,Nkoke C,Kadia BM,Abanda MH,Nganou CN,Abzabji MK,Kingue S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Previous studies have shown controversial results on the role of androgens in coronary artery disease (CAD). We performed this study to assess the relationship between androgen levels and selective coronary angiography (SCA) findings. METHODS:This study was conducted on 502 consecutive men who underwent SCA...

journal_title：Cardiovascular journal of Africa

authors： Davoodi G,Amirezadegan A,Borumand MA,Dehkori MR,Kazemisaeid A,Yaminisharif A

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that the Tp-e interval, which on an electrocardiogram (ECG) is the interval between the peak and the end of the T wave, can be used as an index of transmural dispersion of ventricular repolarisation (TDR). Both Tp-e/QT and Tp-e/QTc ratios have also been used in that capacity. Howeve...

journal_title：Cardiovascular journal of Africa

authors： Kucuk M,Karadeniz C,Ozdemir R,Meşe T

更新日期：2018-11-01 00:00:00

abstract：:Heparin-induced thrombocytopenia (HIT) is a rare but potentially devastating and life-threatening complication from using heparin. HIT not only causes thrombocytopenia, but it also carries an increased risk for fatal thrombotic complications. In this report, we describe the case of a patient in whom fatal HIT develope...

journal_title：Cardiovascular journal of Africa

authors： Nazli Y,Colak N,Demircelik B,Alpay MF,Cakir O,Cagli K

更新日期：2015-05-23 00:00:00

abstract：:Aneurysms of the left atrial appendage are extremely rare. Enlargement of the left atrial appendage can be congenital or acquired. Dysplasia of the left atrial muscles leads to congenital left atrial appendage aneurysm and usually presents as atrial tachyarrhythmia or embolic events in the second or third decade of li...

journal_title：Cardiovascular journal of Africa

authors： Tigen KM,Dogan C,Guler A,Hatipoglu S,Yanartas M,Kirma C

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:We explored the association of N-terminal probrain natriuretic peptide (NT-proBNP) with metabolic traits in a bi-ethnic African-Caucasian cohort. METHODS:Baseline examinations of the Sympathetic activity and Ambulatory Blood Pressure in African (SABPA) prospective cohort study were performed between 2008 an...

journal_title：Cardiovascular journal of Africa

authors： Jujić A,Melander O,Nilsson PM,Malan L,Fedorowski A,Magnusson M

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To identify case fatality rates and predictors of stroke in a private clinic in Kinshasa, Democratic Republic of Congo. METHODS:Two hundred and twelve black Africans were consecutively admitted to a clinic and prospectively assessed during the first 30 days by CT scan-proven stroke types and outcome. Univari...

journal_title：Cardiovascular journal of Africa

authors： Longo-Mbenza B,Lelo Tshinkwela M,Mbuilu Pukuta J

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Cardiac complications of human immunodeficiency virus (HIV) infection are important causes of morbidity and mortality. We set out to determine the electrocardiographic (ECG) abnormalities in treatment-naïve HIV-positive patients in Enugu, south-east Nigeria. METHODS:This was a cross-sectional study involvin...

journal_title：Cardiovascular journal of Africa

authors： Okoye IC,Anyabolu EN

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:Few data are available on heart failure (HF) in sub-Saharan Africa. We aimed to provide a current picture of HF aetiologies in urban Uganda, access to heart surgery, and outcomes. METHODS:We prospectively collected clinical and echocardiographic data from 272 consecutive patients referred for suspected heart...

journal_title：Cardiovascular journal of Africa

authors： Grimaldi A,Ammirati E,Karam N,Vermi AC,de Concilio A,Trucco G,Aloi F,Arioli F,Figini F,Ferrarello S,Sacco FM,Grottola R,D'Arbela PG,Alfieri O,Marijon E,Freers J,Mirabel M

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To document maternal and foetal morbidity and mortality in anticoagulated, pregnant patients with mechanical heart valves until 42 days postpartum. METHODS:In a tertiary single-centre, prospective cohort, 178 consecutive patients at the cardiac-obstetric clinic were screened for warfarin use between 1 July 2...

journal_title：Cardiovascular journal of Africa

authors： Kariv S,Azibani F,Baard J,Osman A,Soma-Pillay P,Anthony J,Sliwa K

更新日期：2018-09-01 00:00:00

abstract：AIM:There are few studies to be found in the literature on ankle-brachial index in sickle cell disease. The aim of this study was to compare ankle-brachial index of steadystate adult sickle cell anaemia patients with that of normal controls. METHODS:A descriptive cross-sectional study of 62 sickle cell anaemia patient...

journal_title：Cardiovascular journal of Africa

authors： Oguanobi NI,Onwubere BJ,Ibegbulam OG,Ike SO,Ejim EC,Agwu O

更新日期：2012-02-01 00:00:00

abstract：:An established relationship exists between human immunodeficiency virus (HIV) and the vascular system, which is characterised by clinical expressions of aneurysmal and occlusive disease that emanate from a common pathological process. The exact pathogenesis is currently unknown; attempts to implicate opportunistic pat...

journal_title：Cardiovascular journal of Africa

authors： Pillay B,Ramdial PK,Naidoo DP

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:Coronary artery bypass grafting (CABG) results in higher morbidity and mortality rates in end-stage renal disease (ESRD) patient populations than in patients with normal renal function. This study aimed to identify the early results of CABG performed on ESRD patients, and the factors that affected the mort...

journal_title：Cardiovascular journal of Africa

authors： Çevirme D,Adademir T,Aksüt M,Örki T,Çakalağaoğlu KC,Alp M,Kirali K

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Cardiac resynchronisation therapy has been shown to be an effective treatment to improve functional status and prolong survival of patients in advanced chronic heart failure. This study assessed the surgical outcomes of left anterior mini-thoracotomy for the implantation of left ventricular epicardial pacing ...

journal_title：Cardiovascular journal of Africa

authors： Ezelsoy M,Bayram M,Yazici S,Yazicioglu N,Sagbas E

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Methods of closing patent ductus arteriosus (PDA) have evolved over time. We review this development in our setting. METHODS:This was a retrospective analysis of children who had transcatheter PDA closure at Chris Hani Baragwanath Hospital between 1993 and 2008. RESULTS:Over 15 years, 1 254 PDAs were diagn...

journal_title：Cardiovascular journal of Africa

authors： Adams PE,Chersich MF,Cilliers A

更新日期：2018-07-01 00:00:00

abstract：:Acute myocardial infarction is a rare complication of dobutamine stress echocardiography. We describe the case of a diabetic patient who presented with an anterior myocardial infarction complicated by an acute pulmonary oedema and cardiogenic collapse during dobutamine stress echocardiography, requiring five days' hos...

journal_title：Cardiovascular journal of Africa

authors： Yameogo NV,Mbaye A,Kagambega LJ,Dioum M,Diagne-Sow D,Kane M,Diack B,Kane A

更新日期：2013-06-23 00:00:00

abstract：INTRODUCTION:A coronary artery anomaly precludes the use of a trans-annular patch in right ventricular outflow tract (RVOT) reconstruction. Herein we present three patients with coronary artery anomalies who underwent total corrective operations without using a conduit. METHODS:Between 2007 and 2010, 84 patients with ...

journal_title：Cardiovascular journal of Africa

authors： Saritas B,Ozker E,Vuran E,Yoruker U,Ayabakan C,Turkoz R

更新日期：2012-03-12 00:00:00