A diagnostic algorithm for pulmonary hypertension due to left heart disease in resource-limited settings: can busy clinicians adopt a simple, practical approach?

abstract：BACKGROUND:Cardiovascular disease (CVD) has been the leading cause of death in developed countries for most of the last century. Most CVD deaths, however, occur in low- and middle-income, developing countries (LMICs) and there is great concern that CVD mortality and burden are rapidly increasing in LMICs as a result of...

journal_title：Cardiovascular journal of Africa

authors： Mensah GA,Roth GA,Sampson UK,Moran AE,Feigin VL,Forouzanfar MH,Naghavi M,Murray CJ,GBD 2013 Mortality and Causes of Death Collaborators.

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Guidelines advise early angiography in non-ST elevation myocardial infarction (NSTEMI) to ensure an optimal outcome. Resource limitations in secondary hospitals in the Western Cape dictate a local guideline to treat NSTEMIs medically with out-patient assessment for angiography, unless mandatory indications f...

journal_title：Cardiovascular journal of Africa

authors： Moses J,Doubell AF,Herbst PG,Klusmann KJ,Weich HS

更新日期：2013-05-01 00:00:00

abstract：:Acute myocardial infarction is a rare complication of dobutamine stress echocardiography. We describe the case of a diabetic patient who presented with an anterior myocardial infarction complicated by an acute pulmonary oedema and cardiogenic collapse during dobutamine stress echocardiography, requiring five days' hos...

journal_title：Cardiovascular journal of Africa

authors： Yameogo NV,Mbaye A,Kagambega LJ,Dioum M,Diagne-Sow D,Kane M,Diack B,Kane A

更新日期：2013-06-23 00:00:00

abstract：BACKGROUND:Methods of closing patent ductus arteriosus (PDA) have evolved over time. We review this development in our setting. METHODS:This was a retrospective analysis of children who had transcatheter PDA closure at Chris Hani Baragwanath Hospital between 1993 and 2008. RESULTS:Over 15 years, 1 254 PDAs were diagn...

journal_title：Cardiovascular journal of Africa

authors： Adams PE,Chersich MF,Cilliers A

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:This prospective study was planned to investigate the frequency and relationship of acquired von Willebrand syndrome (AVWS) with aortic and pulmonary stenosis in patients. METHODS:A total of 84 children, ranging from two to 18 years of age, were enrolled in this study. Of these, 28 had isolated aortic ste...

journal_title：Cardiovascular journal of Africa

authors： Binnetoğlu FK,Babaoğlu K,Filiz ŞG,Zengin E,Altun G,Kılıç SÇ,Sarper N

更新日期：2016-07-01 00:00:00

abstract：:Type 2 diabetic patients treated with statins but still experiencing elevated serum levels of triglycerides (2.3 mmol/l or higher) and low HDL cholesterol (0.8 mmol/l or lower), a pre-specified subgroup, benefited from the addition of fenofibrate to their treatment regimen. Risk of cardiovascular events was reduced by...

journal_title：Cardiovascular journal of Africa

authors： Aalbers J

更新日期：2010-03-01 00:00:00

abstract：:Risk models are widely used to predict outcomes after cardiac surgery. Not only is risk modelling applied in the assessment of the relative impact of specific risk factors on surgical outcomes, but also in patient counselling, the selection of treatment options, comparison of postoperative results, and quality-improve...

journal_title：Cardiovascular journal of Africa

authors： Prins C,de Villiers Jonker I,Botes L,Smit FE

更新日期：2012-04-01 00:00:00

abstract：INTRODUCTION:Rheumatic heart disease (RHD) continues to cause gross distortions of the heart and the associated complications of heart failure and thromboembolic phenomena in this age of numerous high-efficacy drugs and therapeutic interventions. Due to the lack of contemporary local data, there is no national strategy...

journal_title：Cardiovascular journal of Africa

authors： Zhang W,Mondo C,Okello E,Musoke C,Kakande B,Nyakoojo W,Kayima J,Freers J

更新日期：2013-03-01 00:00:00

abstract：AIM:To investigate the osteogenic differentiation of vascular smooth muscle cells (VSMCs) in mice with chronic kidney disease (CKD) and to evaluate the effects of p53 on the osteogenic differentiation of the VSMCs. METHODS:Experimental models of CKD-associated vascular calcification generated by five-sixth (5/6) nephr...

journal_title：Cardiovascular journal of Africa

authors： Li KL,Chen J,Li ZH,Zhao L,He YN

更新日期：2012-07-12 00:00:00

abstract：OBJECTIVE:The surgical approach for effusive constrictive pericarditis (ECP) has not been extensively studied. We present our institution's early and long-term results of pericardiectomy in our cohort of patients with ECP. METHODS:Diagnosis was made primarily by echocardiography. Right heart catheterisation was perfor...

journal_title：Cardiovascular journal of Africa

authors： Buyukbayrak F,Aksoy E,Tas S,Kirali K

更新日期：2013-09-01 00:00:00

abstract：:Hypertension is more prevalent and severe in urban black populations compared to whites, and is associated with a greater degree of target-organ damage for any given blood pressure level. In general, compared to whites, blacks respond well to diuretics and calcium channel blockers and less well to beta-blockers and AC...

journal_title：Cardiovascular journal of Africa

authors： Lindhorst J,Alexander N,Blignaut J,Rayner B

更新日期：2007-07-01 00:00:00

abstract：AIM:Flow-mediated dilatation (FMD) and retinal vascular analysis (RVA) may assist in predicting cardiovascular disease (CVD) but are poorly characterised in South Africa. We recorded baseline FMD and retinal vascular widths in healthy participants, and investigated associations with cardiovascular risk factors. METHOD...

journal_title：Cardiovascular journal of Africa

authors： Marincowitz C,Webster I,Westcott C,Goswami N,de Boever P,Seidel G,Strijdom H

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...

journal_title：Cardiovascular journal of Africa

authors： Siweya H,Monyeki KD

更新日期：2019-01-01 00:00:00

abstract：:A review of heart diseases in Africa shows that the cardiomyopathies continue to be important causes of morbidity and mortality in the population. Hypertension remains the commonest cause of myocardial disease, followed by the cardiomyopathies. Ischaemic heart disease continues to be rare. Of the cardiomyopathies, dil...

journal_title：Cardiovascular journal of Africa

authors： Falase AO,Ogah OS

更新日期：2012-11-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...

journal_title：Cardiovascular journal of Africa

authors： Yolcu M,Gunesdogdu F,Bektas M,Bayirli DT,Serefhanoglu K

更新日期：2020-11-01 00:00:00

abstract：:Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocard...

journal_title：Cardiovascular journal of Africa

authors： McCutcheon K,Manga P

更新日期：2018-01-01 00:00:00

abstract：:Heparin-induced thrombocytopenia (HIT) is a rare but potentially devastating and life-threatening complication from using heparin. HIT not only causes thrombocytopenia, but it also carries an increased risk for fatal thrombotic complications. In this report, we describe the case of a patient in whom fatal HIT develope...

journal_title：Cardiovascular journal of Africa

authors： Nazli Y,Colak N,Demircelik B,Alpay MF,Cakir O,Cagli K

更新日期：2015-05-23 00:00:00

abstract：:Cardiovascular disease (CVD) is the frontrunner in the disease spectrum of sub-Saharan Africa, with stroke and ischaemic heart disease ranked seventh and 14th as leading causes of death, respectively, on this sub-continent. Unfortunately, this region is also grappling with many communicable, maternal, neonatal and nut...

journal_title：Cardiovascular journal of Africa

authors： Ojji DB,Lamont K,Ojji OI,Egenti BN,Sliwa K

更新日期：2017-07-01 00:00:00

abstract：AIM:It has previously been shown that β-blocker therapy reduces QT dynamics in heart failure patients. The aim of this study was to demonstrate this improvement with the third-generation β-blocker, nebivolol. METHODS:A total of 72 heart failure patients with systolic dysfunction were included in the study. Corrected Q...

journal_title：Cardiovascular journal of Africa

authors： Aksoy SM,Cay S,Cagirci G,Sen N

更新日期：2012-05-01 00:00:00

abstract：:We present images of a chest CT scan of an 89-year-old man, showing an area of localised dissection in the convexity of the aortic arch. The ascending and descending aorta were not involved in the disease. The patient suffered a stroke, with severe neurological impairment. Differential diagnosis was undertaken. ...

journal_title：Cardiovascular journal of Africa

authors： Lentini S,Passari G,David A,Gaeta R

更新日期：2009-11-01 00:00:00

abstract：:In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, further complicated by limited therapeutic options and inconsistent follow up. The consequences are ...

journal_title：Cardiovascular journal of Africa

authors： Meyer PW,Anderson R,Ker JA,Ally MT

更新日期：2018-09-01 00:00:00

abstract：:Activation of AMP-activated protein kinase (AMPK) results in glucose transporter 4 (GLUT4) translocation from the cytosol to the cell membrane, and glucose uptake in the skeletal muscles. This increased activation of AMPK can be stimulated by a pharmacological agent, AICAR (5' -aminoimidazole-4-carboxamide ribonucleos...

journal_title：Cardiovascular journal of Africa

authors： Webster I,Friedrich SO,Lochner A,Huisamen B

更新日期：2010-03-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is a relatively common arrhythmia. When AF represents an electrophysiological phenomenon in structurally normal hearts, it is termed lone AF. This study was a retrospective, case-based analysis of patients attending the Cardiac Clinic at Groote Schuur Hospital (GSH) and describes t...

journal_title：Cardiovascular journal of Africa

authors： Thomas V,Schulein S,Millar RN,Mayosi BM

更新日期：2018-09-01 00:00:00

abstract：:This review discusses the 1987 article by Wyndham, Seftel, Pilcher and Baker on familial hypercholesterolaemia (FH) and myocardial infarction (MI) in young Afrikaners, in terms of the significance at the time of publication, as well as the relevance of their findings versus current observations on hypercholesterolaemi...

journal_title：Cardiovascular journal of Africa

authors： Delport R

更新日期：2009-01-01 00:00:00

abstract：:Acute aortic dissection is a life-threatening disease that requires immediate surgical intervention. Although aortic dissection is a rare condition during pregnancy, it is of high risk for both mother and foetus. Most cases of aortic dissection during pregnancy have certain risk factors, including Marfan syndrome and ...

journal_title：Cardiovascular journal of Africa

authors： Simsek Y,Colak C,Yilmaz E,Celik E,Erdil N,Celik O

更新日期：2012-11-23 00:00:00

abstract：OBJECTIVE:Few data are available on heart failure (HF) in sub-Saharan Africa. We aimed to provide a current picture of HF aetiologies in urban Uganda, access to heart surgery, and outcomes. METHODS:We prospectively collected clinical and echocardiographic data from 272 consecutive patients referred for suspected heart...

journal_title：Cardiovascular journal of Africa

authors： Grimaldi A,Ammirati E,Karam N,Vermi AC,de Concilio A,Trucco G,Aloi F,Arioli F,Figini F,Ferrarello S,Sacco FM,Grottola R,D'Arbela PG,Alfieri O,Marijon E,Freers J,Mirabel M

更新日期：2014-09-01 00:00:00

abstract：:The electrocardiographic term 'pause' refers to the prolonged R-R interval that represents the interruption in ventricular depolarisation. This article presents a case of sinus node dysfunction and provides a diagnostic approach to pauses on the ECG. ...

journal_title：Cardiovascular journal of Africa

authors： Viljoen C,Smith R,Chin A

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Cardiac complications of human immunodeficiency virus (HIV) infection are important causes of morbidity and mortality. We set out to determine the electrocardiographic (ECG) abnormalities in treatment-naïve HIV-positive patients in Enugu, south-east Nigeria. METHODS:This was a cross-sectional study involvin...

journal_title：Cardiovascular journal of Africa

authors： Okoye IC,Anyabolu EN

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to report on our experience with upper limb ischaemia (ULI), to define the pattern and distribution of disease, describe key demographic features and report on conventional clinical outcomes. METHODS:This was a single-centre, retrospective, descriptive study. All patients (n = 64)...

journal_title：Cardiovascular journal of Africa

authors： du Toit T,Manning K,Naidoo NG

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:A coronary artery anomaly precludes the use of a trans-annular patch in right ventricular outflow tract (RVOT) reconstruction. Herein we present three patients with coronary artery anomalies who underwent total corrective operations without using a conduit. METHODS:Between 2007 and 2010, 84 patients with ...

journal_title：Cardiovascular journal of Africa

authors： Saritas B,Ozker E,Vuran E,Yoruker U,Ayabakan C,Turkoz R

更新日期：2012-03-12 00:00:00