Non-ST elevation myocardial infarction (NSTEMI) in three hospital settings in South Africa: does geography influence management and outcome? A retrospective cohort study.

abstract：BACKGROUND:Left atrial remodelling (LAR) has been described in Western populations with chronic hypertension and is associated with a higher risk of adverse cardiovascular events. Although hypertension tends to occur earlier and is more severe in sub-Saharan Africa than in more developed nations, LAR and its associated...

journal_title：Cardiovascular journal of Africa

authors： Gounoue AC,Tamdja AD,Choukem SP,Ba H,Aboubakar SM,Nzali A,Halle MP,Nkoke C,Kadia BM,Abanda MH,Nganou CN,Abzabji MK,Kingue S

更新日期：2020-01-01 00:00:00

abstract：:We present the case of a 57-year-old female who experienced iatrogenic left main-stem (LMS) dissection during elective coronary angiography. The dissection immediately affected the circumflex artery (Cx), causing its total distal occlusion, and the left anterior descending artery (LAD), in which a metal stent, implant...

journal_title：Cardiovascular journal of Africa

authors： Zwoliński R,Marcinkiewicz A,Szymczyk K,Pietruszyński R,Jaszewski R

更新日期：2015-11-23 00:00:00

abstract：OBJECTIVE:Circulatory failure due to acute arterial hypertension in the neonatal period is rare. This study was undertaken to assess the clinical and echocardiographic manifestations of circulatory failure resulting from acute neonatal hypertensive crisis. METHODS:Neonatal and cardiology databases from 2007 to 2010 we...

journal_title：Cardiovascular journal of Africa

authors： Louw J,Brown S,Thewissen L,Smits A,Eyskens B,Heying R,Cools B,Levtchenko E,Allegaert K,Gewillig M

更新日期：2013-04-01 00:00:00

abstract：:This study examined the effects of quercetin on spontaneously contracting portal veins isolated from healthy young adult male and female Wistar rats (250-300 g). Quercetin (10(-7)-10(-4) M) always produced significant biphasic effects, comprising an initial brief stimulant effect (rise in basal tone), followed by a su...

journal_title：Cardiovascular journal of Africa

authors： Chiwororo WD,Ojewole JA

更新日期：2010-05-01 00:00:00

abstract：:Resistant hypertension is a common clinical problem in South Africa and is frequently associated with low renin and aldosterone levels, especially in black Africans. In South Africa, novel variants in the epithelial sodium channel (ENaC) have been described to be associated with varying degrees of hypokalaemia and hyp...

journal_title：Cardiovascular journal of Africa

authors： Freercks R,Meldau S,Jones E,Ensor J,Weimers-Willard C,Rayner B

更新日期：2017-09-23 00:00:00

abstract：:Aortic dissection is an uncommon but potentially lethal complication that can occur during the engagement of a guiding catheter. We report a case of a 59-year-old woman with acute aortic dissection due to percutaneous coronary intervention. This resulted in a retrograde extension of the dissection into the proximal p...

journal_title：Cardiovascular journal of Africa

authors： Chunlai S,Stella PR,Belkacemi A,Agostoni P

更新日期：2012-05-12 00:00:00

abstract：:Hypertension is more prevalent and severe in urban black populations compared to whites, and is associated with a greater degree of target-organ damage for any given blood pressure level. In general, compared to whites, blacks respond well to diuretics and calcium channel blockers and less well to beta-blockers and AC...

journal_title：Cardiovascular journal of Africa

authors： Lindhorst J,Alexander N,Blignaut J,Rayner B

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:A four-amino acid deletion was identified within the alpha 2C-adrenergic receptor (alpha 2C Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the alpha 2C Del322-325 polymorphism may be a risk factor for heart fa...

journal_title：Cardiovascular journal of Africa

authors： Du Preez J,Matolweni LO,Greenberg J,Mntla P,Adeyemo AA,Mayosi BM

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Rheumatic heart disease (RHD) continues to cause gross distortions of the heart and the associated complications of heart failure and thromboembolic phenomena in this age of numerous high-efficacy drugs and therapeutic interventions. Due to the lack of contemporary local data, there is no national strategy...

journal_title：Cardiovascular journal of Africa

authors： Zhang W,Mondo C,Okello E,Musoke C,Kakande B,Nyakoojo W,Kayima J,Freers J

更新日期：2013-03-01 00:00:00

abstract：:Risk models are widely used to predict outcomes after cardiac surgery. Not only is risk modelling applied in the assessment of the relative impact of specific risk factors on surgical outcomes, but also in patient counselling, the selection of treatment options, comparison of postoperative results, and quality-improve...

journal_title：Cardiovascular journal of Africa

authors： Prins C,de Villiers Jonker I,Botes L,Smit FE

更新日期：2012-04-01 00:00:00

abstract：AIM:To determine whether a single elevated myocardial performance index (MPI) value in the third trimester of pregnancy is a marker for later adverse obstetric outcomes in stable placental-mediated disease, defined as well-controlled pre-eclampsia (PE) on a single agent and/or uncompensated intra-uterine growth restric...

journal_title：Cardiovascular journal of Africa

authors： Bhorat I,Pillay M,Reddy T

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Methods of closing patent ductus arteriosus (PDA) have evolved over time. We review this development in our setting. METHODS:This was a retrospective analysis of children who had transcatheter PDA closure at Chris Hani Baragwanath Hospital between 1993 and 2008. RESULTS:Over 15 years, 1 254 PDAs were diagn...

journal_title：Cardiovascular journal of Africa

authors： Adams PE,Chersich MF,Cilliers A

更新日期：2018-07-01 00:00:00

abstract：:Pulmonary hypertension (PH) has progressively moved from an orphan disease to a significant global health problem with a major disease burden in limited7hyphen;resource countries, where over 97% of patients live. The aetiologies of PH differ between high- and low-income nations, but PH due to left heart disease is cre...

journal_title：Cardiovascular journal of Africa

authors： Dzudie A,Kengne AP,Lamont K,Dzekem BS,Aminde LN,Abanda MH,Thienemann F,Sliwa K

更新日期：2019-01-01 00:00:00

abstract：:Acute aortic dissection is a life-threatening disease that requires immediate surgical intervention. Although aortic dissection is a rare condition during pregnancy, it is of high risk for both mother and foetus. Most cases of aortic dissection during pregnancy have certain risk factors, including Marfan syndrome and ...

journal_title：Cardiovascular journal of Africa

authors： Simsek Y,Colak C,Yilmaz E,Celik E,Erdil N,Celik O

更新日期：2012-11-23 00:00:00

abstract：:Acute myocardial infarction is a rare complication of dobutamine stress echocardiography. We describe the case of a diabetic patient who presented with an anterior myocardial infarction complicated by an acute pulmonary oedema and cardiogenic collapse during dobutamine stress echocardiography, requiring five days' hos...

journal_title：Cardiovascular journal of Africa

authors： Yameogo NV,Mbaye A,Kagambega LJ,Dioum M,Diagne-Sow D,Kane M,Diack B,Kane A

更新日期：2013-06-23 00:00:00

abstract：OBJECTIVES:Previous studies have suggested that failure of the synthesis of nitric oxide is involved in the pathophysiology of myocardial ischaemia-reperfusion injury. In this study, we investigated the effect of mebudipine, a new dihydropyridine calcium channel blocker, on cardiac function and activity of the myocardi...

journal_title：Cardiovascular journal of Africa

authors： Ghyasi R,Mohammadi M,Badalzadeh R,Rashidi B,Sepehri G

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:Pulmonary embolism (PE) is a potentially fatal disease. In Angola, few data are available on its occurrence. The aim of the study was to characterise the clinical profile, management and outcomes of patients with PE. METHODS:A retrospective observational study was conducted at the Girassol Clinic in Luanda, ...

journal_title：Cardiovascular journal of Africa

authors： Manuel A,Aufico A,Africano R,Peralta T,Salas A,Silva A,Ricardo J,Sabola P,Baião D,Sotolongo C,Neto AD,Martins T,Sabino V,van Dúnem J,Júnior APF

更新日期：2017-11-01 00:00:00

abstract：:Unlike other parts of the world in which cardiomyopathy is rare, heart muscle disease is endemic in Africa. The major forms of cardiomyopathy in Africa are dilated cardiomyopathy (DCM) and endomyocardial fibrosis (EMF). Whereas DCM is a major cause of heart failure throughout the continent, EMF is restricted to the tr...

journal_title：Cardiovascular journal of Africa

authors： Mayosi BM,Somers K

更新日期：2007-05-01 00:00:00

abstract：:Very late bare-metal stent (BMS) thrombosis is unusual in clinical practice. To the best of our knowledge, the latest that the thrombosis of a BMS has been reported is 14 years after implantation. Here, we describe a case of BMS thrombosis that occurred two decades after stenting. A 68-year-old male patient was admitt...

journal_title：Cardiovascular journal of Africa

authors： Acibuca A,Gerede DM,Vurgun VK

更新日期：2015-07-23 00:00:00

abstract：:This review discusses the 1987 article by Wyndham, Seftel, Pilcher and Baker on familial hypercholesterolaemia (FH) and myocardial infarction (MI) in young Afrikaners, in terms of the significance at the time of publication, as well as the relevance of their findings versus current observations on hypercholesterolaemi...

journal_title：Cardiovascular journal of Africa

authors： Delport R

更新日期：2009-01-01 00:00:00

abstract：:We present a case of the native valve used to complete closure of a ruptured aneurysm of the sinus of Valsalva. Aneurysm of the sinus of Valsalva is rare and a non-coronary artery is affected in only 20% of cases. To close the rupture, we decided to use a non-coronary leaflet in a young patient with moderate aortic st...

journal_title：Cardiovascular journal of Africa

authors： Buczkowski P,Walczak M,Stefaniak S,Puślecki M,Katyńska I,Jemielity M

更新日期：2014-08-23 00:00:00

abstract：INTRODUCTION:A coronary artery anomaly precludes the use of a trans-annular patch in right ventricular outflow tract (RVOT) reconstruction. Herein we present three patients with coronary artery anomalies who underwent total corrective operations without using a conduit. METHODS:Between 2007 and 2010, 84 patients with ...

journal_title：Cardiovascular journal of Africa

authors： Saritas B,Ozker E,Vuran E,Yoruker U,Ayabakan C,Turkoz R

更新日期：2012-03-12 00:00:00

abstract：:Optimal maternal body composition during pregnancy is a public health priority due to its implications on maternal health and infant development. We therefore aimed to conduct a systematic review of randomised, controlled trials, and case-control and cohort studies using lifestyle interventions to improve body composi...

journal_title：Cardiovascular journal of Africa

authors： Watson ED,Macaulay S,Lamont K,Gradidge PJ,Pretorius S,Crowther NJ,Libhaber E

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Coronary artery bypass grafting (CABG) results in higher morbidity and mortality rates in end-stage renal disease (ESRD) patient populations than in patients with normal renal function. This study aimed to identify the early results of CABG performed on ESRD patients, and the factors that affected the mort...

journal_title：Cardiovascular journal of Africa

authors： Çevirme D,Adademir T,Aksüt M,Örki T,Çakalağaoğlu KC,Alp M,Kirali K

更新日期：2017-03-01 00:00:00

abstract：:Activation of AMP-activated protein kinase (AMPK) results in glucose transporter 4 (GLUT4) translocation from the cytosol to the cell membrane, and glucose uptake in the skeletal muscles. This increased activation of AMPK can be stimulated by a pharmacological agent, AICAR (5' -aminoimidazole-4-carboxamide ribonucleos...

journal_title：Cardiovascular journal of Africa

authors： Webster I,Friedrich SO,Lochner A,Huisamen B

更新日期：2010-03-01 00:00:00

abstract：:We are deeply saddened by the loss of our great teacher Donald Ross, a truly global mentor in cardiac surgery, a friend, a respectful colleague, an admirer, and custodian of our profession, who passed away on July 7, 2014. ...

journal_title：Cardiovascular journal of Africa

authors： Yankah C

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Previous studies have shown controversial results on the role of androgens in coronary artery disease (CAD). We performed this study to assess the relationship between androgen levels and selective coronary angiography (SCA) findings. METHODS:This study was conducted on 502 consecutive men who underwent SCA...

journal_title：Cardiovascular journal of Africa

authors： Davoodi G,Amirezadegan A,Borumand MA,Dehkori MR,Kazemisaeid A,Yaminisharif A

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To identify socio-demographic and lifestyle determinants of weight gain in a sample of premenopasual black South African (SA) women. METHODS:Changes in body composition (dual-energy X-ray absorptiometry, computerised tomography), socio-economic status (SES) and behavioural/lifestyle factors were measured in ...

journal_title：Cardiovascular journal of Africa

authors： Chantler S,Dickie K,Micklesfield LK,Goedecke JH

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality. In the current prospective study, we addressed the impact of RA on left atrial (LA) function and electrical remodelling. Further, we tried to demonstrate the effects of infliximab, an anti-TNF-alpha agent, on echoc...

journal_title：Cardiovascular journal of Africa

authors： Çetin S,Mustafa G,Keskin G,Yeter E,Doğan M,Öztürk MA

更新日期：2014-07-01 00:00:00

abstract：:Levosimendan was developed as a treatment for acute decompensation of severe heart failure (HF). Its use has evolved during recent years, and new HF treatment strategies in different settings have been developed. This case series aimed to show indications for the use of levosimendan and to discuss the treatment respon...

journal_title：Cardiovascular journal of Africa

authors： Wawrzyniak M,Migaj J,Straburzyńska-Migaj E,Dudek M,Kałużna-Oleksy M

更新日期：2021-01-15 00:00:00