abstract：:Levosimendan was developed as a treatment for acute decompensation of severe heart failure (HF). Its use has evolved during recent years, and new HF treatment strategies in different settings have been developed. This case series aimed to show indications for the use of levosimendan and to discuss the treatment respon...

journal_title：Cardiovascular journal of Africa

authors： Wawrzyniak M,Migaj J,Straburzyńska-Migaj E,Dudek M,Kałużna-Oleksy M

更新日期：2021-01-15 00:00:00

abstract：AIM:Flow-mediated dilatation (FMD) and retinal vascular analysis (RVA) may assist in predicting cardiovascular disease (CVD) but are poorly characterised in South Africa. We recorded baseline FMD and retinal vascular widths in healthy participants, and investigated associations with cardiovascular risk factors. METHOD...

journal_title：Cardiovascular journal of Africa

authors： Marincowitz C,Webster I,Westcott C,Goswami N,de Boever P,Seidel G,Strijdom H

更新日期：2020-11-13 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...

journal_title：Cardiovascular journal of Africa

authors： Yolcu M,Gunesdogdu F,Bektas M,Bayirli DT,Serefhanoglu K

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:We explored the association of N-terminal probrain natriuretic peptide (NT-proBNP) with metabolic traits in a bi-ethnic African-Caucasian cohort. METHODS:Baseline examinations of the Sympathetic activity and Ambulatory Blood Pressure in African (SABPA) prospective cohort study were performed between 2008 an...

journal_title：Cardiovascular journal of Africa

authors： Jujić A,Melander O,Nilsson PM,Malan L,Fedorowski A,Magnusson M

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Dyslipidaemia is a major modifiable risk factor for atherosclerotic cardiovascular disease. At the time the study was conducted, guidelines recommended a low-density lipoprotein cholesterol (LDL-C) target of less than 1.8 mmol/l and a reduction of at least 50% if the baseline LDL-C was between 1.8 and 3.5 mm...

journal_title：Cardiovascular journal of Africa

authors： Blom DJ,Ranjith N,Joshi P,Naidoo P,van Tonder A,Musa MG,Joshi S,Leisegang R,Trokis JS,Makan H,Raal FJ

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Left atrial remodelling (LAR) has been described in Western populations with chronic hypertension and is associated with a higher risk of adverse cardiovascular events. Although hypertension tends to occur earlier and is more severe in sub-Saharan Africa than in more developed nations, LAR and its associated...

journal_title：Cardiovascular journal of Africa

authors： Gounoue AC,Tamdja AD,Choukem SP,Ba H,Aboubakar SM,Nzali A,Halle MP,Nkoke C,Kadia BM,Abanda MH,Nganou CN,Abzabji MK,Kingue S

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Growing evidence has demonstrated that diastolic heart failure occurs in about half of heart failure (HF) patients. We investigated the effects of perindopril on echocardiographic parameters, New York Heart Association (NYHA) functional class and serum N-terminal pro B-type natriuretic peptide (NT-proBNP) ...

journal_title：Cardiovascular journal of Africa

authors： Yuksek U,Cerit L,Eren NK,Ergene O

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...

journal_title：Cardiovascular journal of Africa

authors： Siweya H,Monyeki KD

更新日期：2019-01-01 00:00:00

abstract：:Pulmonary hypertension (PH) has progressively moved from an orphan disease to a significant global health problem with a major disease burden in limited7hyphen;resource countries, where over 97% of patients live. The aetiologies of PH differ between high- and low-income nations, but PH due to left heart disease is cre...

journal_title：Cardiovascular journal of Africa

authors： Dzudie A,Kengne AP,Lamont K,Dzekem BS,Aminde LN,Abanda MH,Thienemann F,Sliwa K

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that the Tp-e interval, which on an electrocardiogram (ECG) is the interval between the peak and the end of the T wave, can be used as an index of transmural dispersion of ventricular repolarisation (TDR). Both Tp-e/QT and Tp-e/QTc ratios have also been used in that capacity. Howeve...

journal_title：Cardiovascular journal of Africa

authors： Kucuk M,Karadeniz C,Ozdemir R,Meşe T

更新日期：2018-11-01 00:00:00

abstract：:In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, further complicated by limited therapeutic options and inconsistent follow up. The consequences are ...

journal_title：Cardiovascular journal of Africa

authors： Meyer PW,Anderson R,Ker JA,Ally MT

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is a relatively common arrhythmia. When AF represents an electrophysiological phenomenon in structurally normal hearts, it is termed lone AF. This study was a retrospective, case-based analysis of patients attending the Cardiac Clinic at Groote Schuur Hospital (GSH) and describes t...

journal_title：Cardiovascular journal of Africa

authors： Thomas V,Schulein S,Millar RN,Mayosi BM

更新日期：2018-09-01 00:00:00

abstract：AIM:To determine whether a single elevated myocardial performance index (MPI) value in the third trimester of pregnancy is a marker for later adverse obstetric outcomes in stable placental-mediated disease, defined as well-controlled pre-eclampsia (PE) on a single agent and/or uncompensated intra-uterine growth restric...

journal_title：Cardiovascular journal of Africa

authors： Bhorat I,Pillay M,Reddy T

更新日期：2018-09-01 00:00:00

abstract：:Peripheral arterial disease (PAD) represents a major public health problem due to its high and increasing prevalence, worldwide distribution, and significant morbidity and mortality rate. Female gender is a risk factor for PAD globally and especially in low-income countries. In this review, we summarise the present kn...

journal_title：Cardiovascular journal of Africa

authors： Comşa HI,Zdrenghea D,Man SC,Pop D

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To document maternal and foetal morbidity and mortality in anticoagulated, pregnant patients with mechanical heart valves until 42 days postpartum. METHODS:In a tertiary single-centre, prospective cohort, 178 consecutive patients at the cardiac-obstetric clinic were screened for warfarin use between 1 July 2...

journal_title：Cardiovascular journal of Africa

authors： Kariv S,Azibani F,Baard J,Osman A,Soma-Pillay P,Anthony J,Sliwa K

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Methods of closing patent ductus arteriosus (PDA) have evolved over time. We review this development in our setting. METHODS:This was a retrospective analysis of children who had transcatheter PDA closure at Chris Hani Baragwanath Hospital between 1993 and 2008. RESULTS:Over 15 years, 1 254 PDAs were diagn...

journal_title：Cardiovascular journal of Africa

authors： Adams PE,Chersich MF,Cilliers A

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to report on our experience with upper limb ischaemia (ULI), to define the pattern and distribution of disease, describe key demographic features and report on conventional clinical outcomes. METHODS:This was a single-centre, retrospective, descriptive study. All patients (n = 64)...

journal_title：Cardiovascular journal of Africa

authors： du Toit T,Manning K,Naidoo NG

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:Few studies have evaluated young adults in their third and fourth decades with coronary artery disease (CAD). This study evaluated the clinical and angiographic profile of young adults ( < 35 years) with CAD. METHODS:A 10-year (2003-2012) retrospective chart review was performed on patients less than 35 yea...

journal_title：Cardiovascular journal of Africa

authors： Pillay AK,Naidoo DP

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Most intra-coronary stents in use are made of 316 L stainless steel, which contains nickel, chromate and molybdenum. Whether inflammatory and allergic reactions to metals contribute to in-stent restenosis is still a matter of debate. AIM:The aim of this study was to ascertain the relationship between metal ...

journal_title：Cardiovascular journal of Africa

authors： Slodownik D,Danenberg C,Merkin D,Swaid F,Moshe S,Ingber A,Lotan H,Durst R

更新日期：2018-01-01 00:00:00

abstract：:Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocard...

journal_title：Cardiovascular journal of Africa

authors： McCutcheon K,Manga P

更新日期：2018-01-01 00:00:00

abstract：:Optimal maternal body composition during pregnancy is a public health priority due to its implications on maternal health and infant development. We therefore aimed to conduct a systematic review of randomised, controlled trials, and case-control and cohort studies using lifestyle interventions to improve body composi...

journal_title：Cardiovascular journal of Africa

authors： Watson ED,Macaulay S,Lamont K,Gradidge PJ,Pretorius S,Crowther NJ,Libhaber E

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Pulmonary embolism (PE) is a potentially fatal disease. In Angola, few data are available on its occurrence. The aim of the study was to characterise the clinical profile, management and outcomes of patients with PE. METHODS:A retrospective observational study was conducted at the Girassol Clinic in Luanda, ...

journal_title：Cardiovascular journal of Africa

authors： Manuel A,Aufico A,Africano R,Peralta T,Salas A,Silva A,Ricardo J,Sabola P,Baião D,Sotolongo C,Neto AD,Martins T,Sabino V,van Dúnem J,Júnior APF

更新日期：2017-11-01 00:00:00

abstract：:Resistant hypertension is a common clinical problem in South Africa and is frequently associated with low renin and aldosterone levels, especially in black Africans. In South Africa, novel variants in the epithelial sodium channel (ENaC) have been described to be associated with varying degrees of hypokalaemia and hyp...

journal_title：Cardiovascular journal of Africa

authors： Freercks R,Meldau S,Jones E,Ensor J,Weimers-Willard C,Rayner B

更新日期：2017-09-23 00:00:00

abstract：BACKGROUND:Cardiac complications of human immunodeficiency virus (HIV) infection are important causes of morbidity and mortality. We set out to determine the electrocardiographic (ECG) abnormalities in treatment-naïve HIV-positive patients in Enugu, south-east Nigeria. METHODS:This was a cross-sectional study involvin...

journal_title：Cardiovascular journal of Africa

authors： Okoye IC,Anyabolu EN

更新日期：2017-09-01 00:00:00

abstract：:The electrocardiographic term 'pause' refers to the prolonged R-R interval that represents the interruption in ventricular depolarisation. This article presents a case of sinus node dysfunction and provides a diagnostic approach to pauses on the ECG. ...

journal_title：Cardiovascular journal of Africa

authors： Viljoen C,Smith R,Chin A

更新日期：2017-07-01 00:00:00

abstract：:Cardiovascular disease (CVD) is the frontrunner in the disease spectrum of sub-Saharan Africa, with stroke and ischaemic heart disease ranked seventh and 14th as leading causes of death, respectively, on this sub-continent. Unfortunately, this region is also grappling with many communicable, maternal, neonatal and nut...

journal_title：Cardiovascular journal of Africa

authors： Ojji DB,Lamont K,Ojji OI,Egenti BN,Sliwa K

更新日期：2017-07-01 00:00:00

abstract：AIM:To provide imaging data and report associations between human immunodeficiency virus (HIV), tuberculosis (TB) and pulmonary embolism (PE) in a South African population that underwent computed tomography pulmonary angiography (CTPA) for suspected PE. METHODS:A validated Qanadli severity scoring system for PE was us...

journal_title：Cardiovascular journal of Africa

authors： Ramlakhan R,Andronikou S,Rajkumar A

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:Coronary artery bypass grafting (CABG) results in higher morbidity and mortality rates in end-stage renal disease (ESRD) patient populations than in patients with normal renal function. This study aimed to identify the early results of CABG performed on ESRD patients, and the factors that affected the mort...

journal_title：Cardiovascular journal of Africa

authors： Çevirme D,Adademir T,Aksüt M,Örki T,Çakalağaoğlu KC,Alp M,Kirali K

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:The functional significance of coronary artery collateral (CAC) vasculature in humans has been debated for decades and this has been compounded by the lack of a standard, systematic, objective method of grading and documenting CAC flow in man. CACs serve as alternative conduits for blood in obstructive cor...

journal_title：Cardiovascular journal of Africa

authors： Ajayi NO,Vanker EA,Satyapal KS

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Paediatric cardiac services in Nigeria have been perceived to be inadequate but no formal documentation of availability and distribution of facilities and services has been done. OBJECTIVE:To evaluate and document the currently available paediatric cardiac services in Nigeria. METHODS:In this questionnaire...

journal_title：Cardiovascular journal of Africa

authors： Ekure EN,Sadoh WE,Bode-Thomas F,Orogade AA,Animasahun AB,Ogunkunle OO,Babaniyi I,Anah MU,Otaigbe BE,Olowu A,Okpokowuruk F,Omokhodion SI,Maduka OC,Onakpoya UU,Adiele DK,Sani UM,Asani M,Yilgwan CS,Daniels Q,Uzodimma C

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Cardiac resynchronisation therapy has been shown to be an effective treatment to improve functional status and prolong survival of patients in advanced chronic heart failure. This study assessed the surgical outcomes of left anterior mini-thoracotomy for the implantation of left ventricular epicardial pacing ...

journal_title：Cardiovascular journal of Africa

authors： Ezelsoy M,Bayram M,Yazici S,Yazicioglu N,Sagbas E

更新日期：2017-01-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the effects of the sphingosine analogue, FTY720 (Fingolimod), on the outcomes of myocardial ischaemia/reperfusion (I/R) injury. METHODS:Two concentrations of FTY720 (1 or 2.5 µM were administered either prior to (PreFTY), or following (PostFTY) 20 minutes' global (GI) or 35 mi...

journal_title：Cardiovascular journal of Africa

authors： van Vuuren D,Marais E,Genade S,Lochner A

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To identify socio-demographic and lifestyle determinants of weight gain in a sample of premenopasual black South African (SA) women. METHODS:Changes in body composition (dual-energy X-ray absorptiometry, computerised tomography), socio-economic status (SES) and behavioural/lifestyle factors were measured in ...

journal_title：Cardiovascular journal of Africa

authors： Chantler S,Dickie K,Micklesfield LK,Goedecke JH

更新日期：2016-11-01 00:00:00

abstract：INTRODUCTION:This prospective study was planned to investigate the frequency and relationship of acquired von Willebrand syndrome (AVWS) with aortic and pulmonary stenosis in patients. METHODS:A total of 84 children, ranging from two to 18 years of age, were enrolled in this study. Of these, 28 had isolated aortic ste...

journal_title：Cardiovascular journal of Africa

authors： Binnetoğlu FK,Babaoğlu K,Filiz ŞG,Zengin E,Altun G,Kılıç SÇ,Sarper N

更新日期：2016-07-01 00:00:00

abstract：:Takotsubo cardiomyopathy (TCMP) is characterised by a temporary aneurysm of the left ventricular apex in individuals without significant stenosis of the coronary arteries. It is extremely rare to see it combined with a thrombus. In this case report, we present a 57-year-old female patient with TCMP in whom apical thro...

journal_title：Cardiovascular journal of Africa

authors： Icli A,Akilli H,Kayrak M,Aribas A,Ozdemir K

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Although many reports have detailed the advantages and disadvantages between femoral and subclavian arterial cannulations for acute aortic dissection type A (AADA), the confounding factors caused by disease severity and surgical procedures could not be completely eliminated. We compared femoral and subclavia...

journal_title：Cardiovascular journal of Africa

authors： Hsu PS,Chen JL,Tsai CS,Tsai YT,Lin CY,Lee CY,Ke HY,Lin YC

更新日期：2016-05-01 00:00:00

abstract：:Cardiovascular conditions associated with pregnancy are serious complications. In general, depression is a well-known risk indicator for cardiovascular disease (CVD). Mental distress and depression are associated with physiological responses such as inflammation and oxidative stress. Both inflammation and oxidative st...

journal_title：Cardiovascular journal of Africa

authors： Nicholson L,Lecour S,Wedegärtner S,Kindermann I,Böhm M,Sliwa K

更新日期：2016-03-01 00:00:00

abstract：:We present the case of a 57-year-old female who experienced iatrogenic left main-stem (LMS) dissection during elective coronary angiography. The dissection immediately affected the circumflex artery (Cx), causing its total distal occlusion, and the left anterior descending artery (LAD), in which a metal stent, implant...

journal_title：Cardiovascular journal of Africa

authors： Zwoliński R,Marcinkiewicz A,Szymczyk K,Pietruszyński R,Jaszewski R

更新日期：2015-11-23 00:00:00

abstract：:Very late bare-metal stent (BMS) thrombosis is unusual in clinical practice. To the best of our knowledge, the latest that the thrombosis of a BMS has been reported is 14 years after implantation. Here, we describe a case of BMS thrombosis that occurred two decades after stenting. A 68-year-old male patient was admitt...

journal_title：Cardiovascular journal of Africa

authors： Acibuca A,Gerede DM,Vurgun VK

更新日期：2015-07-23 00:00:00

abstract：OBJECTIVES:Little is known about the performance of re-used pacemakers and implantable cardioverter defibrillators (ICDs) in Africa. We sought to compare the risk of infection and the rate of malfunction of re-used pacemakers and ICDs with new devices implanted at Groote Schuur Hospital in Cape Town, South Africa. MET...

journal_title：Cardiovascular journal of Africa

authors： Jama ZV,Chin A,Badri M,Mayosi BM

更新日期：2015-07-01 00:00:00