In memoriam: Mr Donald Nixon Ross 4 October 1922 to 7 July 2014 (91 years).

abstract：INTRODUCTION:Atrial fibrillation (AF) is a relatively common arrhythmia. When AF represents an electrophysiological phenomenon in structurally normal hearts, it is termed lone AF. This study was a retrospective, case-based analysis of patients attending the Cardiac Clinic at Groote Schuur Hospital (GSH) and describes t...

journal_title：Cardiovascular journal of Africa

authors： Thomas V,Schulein S,Millar RN,Mayosi BM

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to report on our experience with upper limb ischaemia (ULI), to define the pattern and distribution of disease, describe key demographic features and report on conventional clinical outcomes. METHODS:This was a single-centre, retrospective, descriptive study. All patients (n = 64)...

journal_title：Cardiovascular journal of Africa

authors： du Toit T,Manning K,Naidoo NG

更新日期：2018-03-01 00:00:00

abstract：:An established relationship exists between human immunodeficiency virus (HIV) and the vascular system, which is characterised by clinical expressions of aneurysmal and occlusive disease that emanate from a common pathological process. The exact pathogenesis is currently unknown; attempts to implicate opportunistic pat...

journal_title：Cardiovascular journal of Africa

authors： Pillay B,Ramdial PK,Naidoo DP

更新日期：2015-03-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...

journal_title：Cardiovascular journal of Africa

authors： Yolcu M,Gunesdogdu F,Bektas M,Bayirli DT,Serefhanoglu K

更新日期：2020-11-01 00:00:00

abstract：AIM:To investigate the osteogenic differentiation of vascular smooth muscle cells (VSMCs) in mice with chronic kidney disease (CKD) and to evaluate the effects of p53 on the osteogenic differentiation of the VSMCs. METHODS:Experimental models of CKD-associated vascular calcification generated by five-sixth (5/6) nephr...

journal_title：Cardiovascular journal of Africa

authors： Li KL,Chen J,Li ZH,Zhao L,He YN

更新日期：2012-07-12 00:00:00

abstract：BACKGROUND:Dyslipidaemia is a major modifiable risk factor for atherosclerotic cardiovascular disease. At the time the study was conducted, guidelines recommended a low-density lipoprotein cholesterol (LDL-C) target of less than 1.8 mmol/l and a reduction of at least 50% if the baseline LDL-C was between 1.8 and 3.5 mm...

journal_title：Cardiovascular journal of Africa

authors： Blom DJ,Ranjith N,Joshi P,Naidoo P,van Tonder A,Musa MG,Joshi S,Leisegang R,Trokis JS,Makan H,Raal FJ

更新日期：2020-09-01 00:00:00

abstract：:We report on a patient who developed cardiogenic shock caused by dynamic left ventricular outflow tract (LVOT) obstruction following percutaneous coronary intervention for anteroseptal acute myocardial infarction. ...

journal_title：Cardiovascular journal of Africa

authors： Karabay CY,Kocabay G,Kalayci A,Tanboga H,Mert M,Kirma C

更新日期：2011-07-01 00:00:00

abstract：AIM:To determine whether a single elevated myocardial performance index (MPI) value in the third trimester of pregnancy is a marker for later adverse obstetric outcomes in stable placental-mediated disease, defined as well-controlled pre-eclampsia (PE) on a single agent and/or uncompensated intra-uterine growth restric...

journal_title：Cardiovascular journal of Africa

authors： Bhorat I,Pillay M,Reddy T

更新日期：2018-09-01 00:00:00

abstract：:Angiogenic imbalance contributes to the development of preeclampsia. We evaluated the protein expression of the proangiogenic placental growth factor (PlGF) and transforming growth factor beta 1 (TGF-β1) compared with the anti-angiogenic soluble fms-like tyrosine kinase receptor (sFlt1) and soluble endoglin (sEng) in ...

journal_title：Cardiovascular journal of Africa

authors： Govender N,Naicker T,Moodley J

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) has been the leading cause of death in developed countries for most of the last century. Most CVD deaths, however, occur in low- and middle-income, developing countries (LMICs) and there is great concern that CVD mortality and burden are rapidly increasing in LMICs as a result of...

journal_title：Cardiovascular journal of Africa

authors： Mensah GA,Roth GA,Sampson UK,Moran AE,Feigin VL,Forouzanfar MH,Naghavi M,Murray CJ,GBD 2013 Mortality and Causes of Death Collaborators.

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...

journal_title：Cardiovascular journal of Africa

authors： Siweya H,Monyeki KD

更新日期：2019-01-01 00:00:00

abstract：:We present the case of a three-month-old infant with a giant right atrial myxoma obstructing the tricuspid valve, who following haemodynamic deterioration and cardiac arrest, was operated upon as an emergency. On echocardiogram, there was a mass attached to the tricuspid annulus, in close proximity to the septal leaf...

journal_title：Cardiovascular journal of Africa

authors： Vuran C,Babaoglu K,Ozker E,Ayabakan C,Saritas B,Kocyigit OI,Turkoz R

更新日期：2012-02-12 00:00:00

abstract：OBJECTIVES:Few studies have evaluated young adults in their third and fourth decades with coronary artery disease (CAD). This study evaluated the clinical and angiographic profile of young adults ( < 35 years) with CAD. METHODS:A 10-year (2003-2012) retrospective chart review was performed on patients less than 35 yea...

journal_title：Cardiovascular journal of Africa

authors： Pillay AK,Naidoo DP

更新日期：2018-01-01 00:00:00

abstract：:We present a case of an 85-year-old man with acute myocardial infarction and cardiogenic shock due to left main coronary artery occlusion, with spontaneous dissection of the right coronary artery. ...

journal_title：Cardiovascular journal of Africa

authors： Karabay CY,Kocabay G,Kalayci A,Zehir R,Mert M,Kirma C

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:We explored the association of N-terminal probrain natriuretic peptide (NT-proBNP) with metabolic traits in a bi-ethnic African-Caucasian cohort. METHODS:Baseline examinations of the Sympathetic activity and Ambulatory Blood Pressure in African (SABPA) prospective cohort study were performed between 2008 an...

journal_title：Cardiovascular journal of Africa

authors： Jujić A,Melander O,Nilsson PM,Malan L,Fedorowski A,Magnusson M

更新日期：2020-11-01 00:00:00

abstract：:Optimal maternal body composition during pregnancy is a public health priority due to its implications on maternal health and infant development. We therefore aimed to conduct a systematic review of randomised, controlled trials, and case-control and cohort studies using lifestyle interventions to improve body composi...

journal_title：Cardiovascular journal of Africa

authors： Watson ED,Macaulay S,Lamont K,Gradidge PJ,Pretorius S,Crowther NJ,Libhaber E

更新日期：2017-11-01 00:00:00

abstract：AIM:It has previously been shown that β-blocker therapy reduces QT dynamics in heart failure patients. The aim of this study was to demonstrate this improvement with the third-generation β-blocker, nebivolol. METHODS:A total of 72 heart failure patients with systolic dysfunction were included in the study. Corrected Q...

journal_title：Cardiovascular journal of Africa

authors： Aksoy SM,Cay S,Cagirci G,Sen N

更新日期：2012-05-01 00:00:00

abstract：:Acute type II aortic dissection and aortic coarctation are rare combined disorders. This report is of a patient with coarctation, a bicuspid aortic valve and type II dissection, who underwent emergency repair for the dissection, with aortic valve preservation. Repair of the coarctation was planned for a future occasio...

journal_title：Cardiovascular journal of Africa

authors： Bezgin T,Doğan C,Elveran A,Karagöz A,Yücel C,Esen AM

更新日期：2013-09-23 00:00:00

abstract：:Levosimendan was developed as a treatment for acute decompensation of severe heart failure (HF). Its use has evolved during recent years, and new HF treatment strategies in different settings have been developed. This case series aimed to show indications for the use of levosimendan and to discuss the treatment respon...

journal_title：Cardiovascular journal of Africa

authors： Wawrzyniak M,Migaj J,Straburzyńska-Migaj E,Dudek M,Kałużna-Oleksy M

更新日期：2021-01-15 00:00:00

abstract：AIM:The aim of this study was to evaluate the effects of the sphingosine analogue, FTY720 (Fingolimod), on the outcomes of myocardial ischaemia/reperfusion (I/R) injury. METHODS:Two concentrations of FTY720 (1 or 2.5 µM were administered either prior to (PreFTY), or following (PostFTY) 20 minutes' global (GI) or 35 mi...

journal_title：Cardiovascular journal of Africa

authors： van Vuuren D,Marais E,Genade S,Lochner A

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Few data are available on heart failure (HF) in sub-Saharan Africa. We aimed to provide a current picture of HF aetiologies in urban Uganda, access to heart surgery, and outcomes. METHODS:We prospectively collected clinical and echocardiographic data from 272 consecutive patients referred for suspected heart...

journal_title：Cardiovascular journal of Africa

authors： Grimaldi A,Ammirati E,Karam N,Vermi AC,de Concilio A,Trucco G,Aloi F,Arioli F,Figini F,Ferrarello S,Sacco FM,Grottola R,D'Arbela PG,Alfieri O,Marijon E,Freers J,Mirabel M

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that the Tp-e interval, which on an electrocardiogram (ECG) is the interval between the peak and the end of the T wave, can be used as an index of transmural dispersion of ventricular repolarisation (TDR). Both Tp-e/QT and Tp-e/QTc ratios have also been used in that capacity. Howeve...

journal_title：Cardiovascular journal of Africa

authors： Kucuk M,Karadeniz C,Ozdemir R,Meşe T

更新日期：2018-11-01 00:00:00

abstract：:Pulmonary hypertension (PH) has progressively moved from an orphan disease to a significant global health problem with a major disease burden in limited7hyphen;resource countries, where over 97% of patients live. The aetiologies of PH differ between high- and low-income nations, but PH due to left heart disease is cre...

journal_title：Cardiovascular journal of Africa

authors： Dzudie A,Kengne AP,Lamont K,Dzekem BS,Aminde LN,Abanda MH,Thienemann F,Sliwa K

更新日期：2019-01-01 00:00:00

abstract：:Heparin-induced thrombocytopenia (HIT) is a rare but potentially devastating and life-threatening complication from using heparin. HIT not only causes thrombocytopenia, but it also carries an increased risk for fatal thrombotic complications. In this report, we describe the case of a patient in whom fatal HIT develope...

journal_title：Cardiovascular journal of Africa

authors： Nazli Y,Colak N,Demircelik B,Alpay MF,Cakir O,Cagli K

更新日期：2015-05-23 00:00:00

abstract：INTRODUCTION:Rheumatic heart disease (RHD) continues to cause gross distortions of the heart and the associated complications of heart failure and thromboembolic phenomena in this age of numerous high-efficacy drugs and therapeutic interventions. Due to the lack of contemporary local data, there is no national strategy...

journal_title：Cardiovascular journal of Africa

authors： Zhang W,Mondo C,Okello E,Musoke C,Kakande B,Nyakoojo W,Kayima J,Freers J

更新日期：2013-03-01 00:00:00

abstract：:The year 2011 marks the 30th anniversary of the founding of the Pan-African Society of Cardiology (PASCAR). Throughout its brief history, PASCAR has been integral to improving the cardiovascular health of the people of Africa. During the past three decades, many African countries have been vulnerable to political and ...

journal_title：Cardiovascular journal of Africa

authors： Watkins D,Omokhodion SI,Mayosi BM

更新日期：2011-05-01 00:00:00

abstract：:We present the case of a 57-year-old female who experienced iatrogenic left main-stem (LMS) dissection during elective coronary angiography. The dissection immediately affected the circumflex artery (Cx), causing its total distal occlusion, and the left anterior descending artery (LAD), in which a metal stent, implant...

journal_title：Cardiovascular journal of Africa

authors： Zwoliński R,Marcinkiewicz A,Szymczyk K,Pietruszyński R,Jaszewski R

更新日期：2015-11-23 00:00:00

abstract：:Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocard...

journal_title：Cardiovascular journal of Africa

authors： McCutcheon K,Manga P

更新日期：2018-01-01 00:00:00

abstract：:Unlike other parts of the world in which cardiomyopathy is rare, heart muscle disease is endemic in Africa. The major forms of cardiomyopathy in Africa are dilated cardiomyopathy (DCM) and endomyocardial fibrosis (EMF). Whereas DCM is a major cause of heart failure throughout the continent, EMF is restricted to the tr...

journal_title：Cardiovascular journal of Africa

authors： Mayosi BM,Somers K

更新日期：2007-05-01 00:00:00

abstract：:Activation of AMP-activated protein kinase (AMPK) results in glucose transporter 4 (GLUT4) translocation from the cytosol to the cell membrane, and glucose uptake in the skeletal muscles. This increased activation of AMPK can be stimulated by a pharmacological agent, AICAR (5' -aminoimidazole-4-carboxamide ribonucleos...

journal_title：Cardiovascular journal of Africa

authors： Webster I,Friedrich SO,Lochner A,Huisamen B

更新日期：2010-03-01 00:00:00