Atherosclerotic disease is the predominant aetiology of acute coronary syndrome in young adults.

Abstract:

OBJECTIVES:Few studies have evaluated young adults in their third and fourth decades with coronary artery disease (CAD). This study evaluated the clinical and angiographic profile of young adults ( < 35 years) with CAD. METHODS:A 10-year (2003-2012) retrospective chart review was performed on patients less than 35 years diagnosed with CAD at Inkosi Albert Luthuli Central Hospital, Durban. RESULTS:Of the 100 patients who met the study criteria, the majority were male (90%), of Indian ethnicity (79%), and presented with acute coronary syndrome (93%). Smoking (82%), dyslipidaemia (79%) and dysglycaemia (75%) were the most prevalent risk factors. Almost half of the subjects (48%) met criteria for the metabolic syndrome. Angiographic findings revealed multi-vessel (42%), single-vessel (36%) and non-occlusive disease (20%); only two subjects had normal epicardial vessels. Disease severity was influenced by dyslipidaemia (p = 0.002) and positive family history (p = 0.002). Non-coronary aetiologies were identified in 19% of subjects. CONCLUSION:Atherosclerotic disease associated with risk-factor clustering was highly prevalent in young adults with CAD.

journal_name

Cardiovasc J Afr

authors

Pillay AK,Naidoo DP

doi

10.5830/CVJA-2017-035

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

36-42

issue

1

eissn

1995-1892

issn

1680-0745

journal_volume

29

pub_type

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