Abstract：
BACKGROUND:Recent studies have shown that the Tp-e interval, which on an electrocardiogram (ECG) is the interval between the peak and the end of the T wave, can be used as an index of transmural dispersion of ventricular repolarisation (TDR). Both Tp-e/QT and Tp-e/QTc ratios have also been used in that capacity. However, these novel repolarisation indices have not previously been studied in children with acute rheumaticcarditis (ARC). METHODS:A hundred and thirty-nine children who were diagnosed with ARC and 153 age- and gender-matched healthy controls were retrospectively reviewed. Twelve-lead ECGs were used to evaluate P-wave, QT and QTc dispersions, Tp-e interval, and Tp-e/QT and Tp-e/QT ratios. RESULTS:The mean age of the patients was 10.9 ± 2.4 years. The P-wave, QT and QTc dispersions were significantly higher in patients compared to the healthy control subjects. The Tp-e interval, and Tp-e/QT and Tp-e/QTc ratios were also significantly increased in patients compared to the controls. When the patients were compared in terms of either one- or two-valve involvement, we found no difference between the groups regarding P-wave, QTd and QTc dispersions, Tp-e interval, and Tp-e/QT and Tp-e/QT c ratios. There was no correlation between acute-phase reactants, white blood cell count and these repolarisation parameters. CONCLUSIONS:This study showed that the new transmural dispersion of ventricular repolarisation parameters, Tp-e interval, Tp-e/QT ratios and QTd were increased in children with ARC. Prolongation of the Tp-e interval and an increased Tp-e/QT ratio might be useful markers for predicting myocardial involvement in children with ARC.
journal_name
Cardiovasc J Afrjournal_title
Cardiovascular journal of Africaauthors
Kucuk M,Karadeniz C,Ozdemir R,Meşe Tdoi
10.5830/CVJA-2018-043subject
Has Abstractpub_date
2018-11-01 00:00:00pages
362-365issue
6eissn
1995-1892issn
1680-0745journal_volume
29pub_type
杂志文章abstract：:Pulmonary hypertension (PH) has progressively moved from an orphan disease to a significant global health problem with a major disease burden in limited7hyphen;resource countries, where over 97% of patients live. The aetiologies of PH differ between high- and low-income nations, but PH due to left heart disease is cre...
journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章,评审
doi：10.5830/CVJA-2018-042
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abstract：:Acute type II aortic dissection and aortic coarctation are rare combined disorders. This report is of a patient with coarctation, a bicuspid aortic valve and type II dissection, who underwent emergency repair for the dissection, with aortic valve preservation. Repair of the coarctation was planned for a future occasio...
journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2013-064
更新日期：2013-09-23 00:00:00
abstract：:Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocard...
journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章,评审
doi：10.5830/CVJA-2017-009
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abstract：:This review discusses the 1987 article by Wyndham, Seftel, Pilcher and Baker on familial hypercholesterolaemia (FH) and myocardial infarction (MI) in young Afrikaners, in terms of the significance at the time of publication, as well as the relevance of their findings versus current observations on hypercholesterolaemi...
journal_title：Cardiovascular journal of Africa
pub_type： 历史文章,杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:We present a case of the native valve used to complete closure of a ruptured aneurysm of the sinus of Valsalva. Aneurysm of the sinus of Valsalva is rare and a non-coronary artery is affected in only 20% of cases. To close the rupture, we decided to use a non-coronary leaflet in a young patient with moderate aortic st...
journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2014-020
更新日期：2014-08-23 00:00:00
abstract：BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...
journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2018-059
更新日期：2019-01-01 00:00:00
abstract：INTRODUCTION:Rheumatic heart disease (RHD) continues to cause gross distortions of the heart and the associated complications of heart failure and thromboembolic phenomena in this age of numerous high-efficacy drugs and therapeutic interventions. Due to the lack of contemporary local data, there is no national strategy...
journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2012-076
更新日期：2013-03-01 00:00:00
abstract：:Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...
journal_title：Cardiovascular journal of Africa
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doi：10.5830-CVJA-2020-016
更新日期：2020-11-01 00:00:00
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2017-017
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2011-004
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2017-013
更新日期：2017-09-01 00:00:00
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章,多中心研究
doi：10.5830/CVJA-2013-017
更新日期：2013-05-01 00:00:00
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2015-060
更新日期：2015-11-23 00:00:00
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2017-012
更新日期：2017-09-23 00:00:00
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：10.5830/CVJA-2017-041
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章,评审
doi：10.5830/CVJA-2016-082
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章,随机对照试验
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
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journal_title：Cardiovascular journal of Africa
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doi：10.5830/CVJA-2015-093
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章,多中心研究
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journal_title：Cardiovascular journal of Africa
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journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
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更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:A four-amino acid deletion was identified within the alpha 2C-adrenergic receptor (alpha 2C Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the alpha 2C Del322-325 polymorphism may be a risk factor for heart fa...
journal_title：Cardiovascular journal of Africa
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
