The effect of perindopril on echocardiographic parameters, NYHA functional class and serum NT-proBNP values in patients with diastolic heart failure.

abstract：:Unlike other parts of the world in which cardiomyopathy is rare, heart muscle disease is endemic in Africa. The major forms of cardiomyopathy in Africa are dilated cardiomyopathy (DCM) and endomyocardial fibrosis (EMF). Whereas DCM is a major cause of heart failure throughout the continent, EMF is restricted to the tr...

journal_title：Cardiovascular journal of Africa

authors： Mayosi BM,Somers K

更新日期：2007-05-01 00:00:00

abstract：:This study examined the effects of quercetin on spontaneously contracting portal veins isolated from healthy young adult male and female Wistar rats (250-300 g). Quercetin (10(-7)-10(-4) M) always produced significant biphasic effects, comprising an initial brief stimulant effect (rise in basal tone), followed by a su...

journal_title：Cardiovascular journal of Africa

authors： Chiwororo WD,Ojewole JA

更新日期：2010-05-01 00:00:00

abstract：AIM:To determine whether a single elevated myocardial performance index (MPI) value in the third trimester of pregnancy is a marker for later adverse obstetric outcomes in stable placental-mediated disease, defined as well-controlled pre-eclampsia (PE) on a single agent and/or uncompensated intra-uterine growth restric...

journal_title：Cardiovascular journal of Africa

authors： Bhorat I,Pillay M,Reddy T

更新日期：2018-09-01 00:00:00

abstract：:We describe the case of a patient who developed torsade de pointes during temporary pacemaker insertion after administration of intravenous erythromycin. The case highlights the dangers of administering drugs that prolong the QT interval in patients with complete atrioventricular block, and we discuss the underlying p...

journal_title：Cardiovascular journal of Africa

authors： McCutcheon K,Manga P

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:The surgical approach for effusive constrictive pericarditis (ECP) has not been extensively studied. We present our institution's early and long-term results of pericardiectomy in our cohort of patients with ECP. METHODS:Diagnosis was made primarily by echocardiography. Right heart catheterisation was perfor...

journal_title：Cardiovascular journal of Africa

authors： Buyukbayrak F,Aksoy E,Tas S,Kirali K

更新日期：2013-09-01 00:00:00

abstract：:This review discusses the 1987 article by Wyndham, Seftel, Pilcher and Baker on familial hypercholesterolaemia (FH) and myocardial infarction (MI) in young Afrikaners, in terms of the significance at the time of publication, as well as the relevance of their findings versus current observations on hypercholesterolaemi...

journal_title：Cardiovascular journal of Africa

authors： Delport R

更新日期：2009-01-01 00:00:00

abstract：:Risk models are widely used to predict outcomes after cardiac surgery. Not only is risk modelling applied in the assessment of the relative impact of specific risk factors on surgical outcomes, but also in patient counselling, the selection of treatment options, comparison of postoperative results, and quality-improve...

journal_title：Cardiovascular journal of Africa

authors： Prins C,de Villiers Jonker I,Botes L,Smit FE

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...

journal_title：Cardiovascular journal of Africa

authors： Siweya H,Monyeki KD

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Pulmonary thromboembolism (PTE) may increase D-dimer and decrease fibrinogen levels. However, in settings such as intensive care units (ICU) and in long-term hospitalised patients, several factors may influence D-dimer and fibrinogen concentrations and make them unreliable indicators for the diagnosis of P...

journal_title：Cardiovascular journal of Africa

authors： Hajsadeghi S,Kerman SR,Khojandi M,Vaferi H,Ramezani R,Jourshari NM,Mousavi SA,Pouraliakbar H

更新日期：2012-09-01 00:00:00

abstract：AIM:To provide imaging data and report associations between human immunodeficiency virus (HIV), tuberculosis (TB) and pulmonary embolism (PE) in a South African population that underwent computed tomography pulmonary angiography (CTPA) for suspected PE. METHODS:A validated Qanadli severity scoring system for PE was us...

journal_title：Cardiovascular journal of Africa

authors： Ramlakhan R,Andronikou S,Rajkumar A

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:The functional significance of coronary artery collateral (CAC) vasculature in humans has been debated for decades and this has been compounded by the lack of a standard, systematic, objective method of grading and documenting CAC flow in man. CACs serve as alternative conduits for blood in obstructive cor...

journal_title：Cardiovascular journal of Africa

authors： Ajayi NO,Vanker EA,Satyapal KS

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Little is known about the performance of re-used pacemakers and implantable cardioverter defibrillators (ICDs) in Africa. We sought to compare the risk of infection and the rate of malfunction of re-used pacemakers and ICDs with new devices implanted at Groote Schuur Hospital in Cape Town, South Africa. MET...

journal_title：Cardiovascular journal of Africa

authors： Jama ZV,Chin A,Badri M,Mayosi BM

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Guidelines advise early angiography in non-ST elevation myocardial infarction (NSTEMI) to ensure an optimal outcome. Resource limitations in secondary hospitals in the Western Cape dictate a local guideline to treat NSTEMIs medically with out-patient assessment for angiography, unless mandatory indications f...

journal_title：Cardiovascular journal of Africa

authors： Moses J,Doubell AF,Herbst PG,Klusmann KJ,Weich HS

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Cardiac complications of human immunodeficiency virus (HIV) infection are important causes of morbidity and mortality. We set out to determine the electrocardiographic (ECG) abnormalities in treatment-naïve HIV-positive patients in Enugu, south-east Nigeria. METHODS:This was a cross-sectional study involvin...

journal_title：Cardiovascular journal of Africa

authors： Okoye IC,Anyabolu EN

更新日期：2017-09-01 00:00:00

abstract：AIM:Flow-mediated dilatation (FMD) and retinal vascular analysis (RVA) may assist in predicting cardiovascular disease (CVD) but are poorly characterised in South Africa. We recorded baseline FMD and retinal vascular widths in healthy participants, and investigated associations with cardiovascular risk factors. METHOD...

journal_title：Cardiovascular journal of Africa

authors： Marincowitz C,Webster I,Westcott C,Goswami N,de Boever P,Seidel G,Strijdom H

更新日期：2020-11-13 00:00:00

abstract：OBJECTIVE:Pulmonary embolism (PE) is a potentially fatal disease. In Angola, few data are available on its occurrence. The aim of the study was to characterise the clinical profile, management and outcomes of patients with PE. METHODS:A retrospective observational study was conducted at the Girassol Clinic in Luanda, ...

journal_title：Cardiovascular journal of Africa

authors： Manuel A,Aufico A,Africano R,Peralta T,Salas A,Silva A,Ricardo J,Sabola P,Baião D,Sotolongo C,Neto AD,Martins T,Sabino V,van Dúnem J,Júnior APF

更新日期：2017-11-01 00:00:00

abstract：:Heparin-induced thrombocytopenia (HIT) is a rare but potentially devastating and life-threatening complication from using heparin. HIT not only causes thrombocytopenia, but it also carries an increased risk for fatal thrombotic complications. In this report, we describe the case of a patient in whom fatal HIT develope...

journal_title：Cardiovascular journal of Africa

authors： Nazli Y,Colak N,Demircelik B,Alpay MF,Cakir O,Cagli K

更新日期：2015-05-23 00:00:00

abstract：:An established relationship exists between human immunodeficiency virus (HIV) and the vascular system, which is characterised by clinical expressions of aneurysmal and occlusive disease that emanate from a common pathological process. The exact pathogenesis is currently unknown; attempts to implicate opportunistic pat...

journal_title：Cardiovascular journal of Africa

authors： Pillay B,Ramdial PK,Naidoo DP

更新日期：2015-03-01 00:00:00

abstract：:We present a case of the native valve used to complete closure of a ruptured aneurysm of the sinus of Valsalva. Aneurysm of the sinus of Valsalva is rare and a non-coronary artery is affected in only 20% of cases. To close the rupture, we decided to use a non-coronary leaflet in a young patient with moderate aortic st...

journal_title：Cardiovascular journal of Africa

authors： Buczkowski P,Walczak M,Stefaniak S,Puślecki M,Katyńska I,Jemielity M

更新日期：2014-08-23 00:00:00

abstract：BACKGROUND:A four-amino acid deletion was identified within the alpha 2C-adrenergic receptor (alpha 2C Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the alpha 2C Del322-325 polymorphism may be a risk factor for heart fa...

journal_title：Cardiovascular journal of Africa

authors： Du Preez J,Matolweni LO,Greenberg J,Mntla P,Adeyemo AA,Mayosi BM

更新日期：2008-01-01 00:00:00

abstract：:Resistant hypertension is a common clinical problem in South Africa and is frequently associated with low renin and aldosterone levels, especially in black Africans. In South Africa, novel variants in the epithelial sodium channel (ENaC) have been described to be associated with varying degrees of hypokalaemia and hyp...

journal_title：Cardiovascular journal of Africa

authors： Freercks R,Meldau S,Jones E,Ensor J,Weimers-Willard C,Rayner B

更新日期：2017-09-23 00:00:00

abstract：OBJECTIVES:Previous studies have suggested that failure of the synthesis of nitric oxide is involved in the pathophysiology of myocardial ischaemia-reperfusion injury. In this study, we investigated the effect of mebudipine, a new dihydropyridine calcium channel blocker, on cardiac function and activity of the myocardi...

journal_title：Cardiovascular journal of Africa

authors： Ghyasi R,Mohammadi M,Badalzadeh R,Rashidi B,Sepehri G

更新日期：2011-11-01 00:00:00

abstract：:We are deeply saddened by the loss of our great teacher Donald Ross, a truly global mentor in cardiac surgery, a friend, a respectful colleague, an admirer, and custodian of our profession, who passed away on July 7, 2014. ...

journal_title：Cardiovascular journal of Africa

authors： Yankah C

更新日期：2014-07-01 00:00:00

abstract：AIM:To investigate the osteogenic differentiation of vascular smooth muscle cells (VSMCs) in mice with chronic kidney disease (CKD) and to evaluate the effects of p53 on the osteogenic differentiation of the VSMCs. METHODS:Experimental models of CKD-associated vascular calcification generated by five-sixth (5/6) nephr...

journal_title：Cardiovascular journal of Africa

authors： Li KL,Chen J,Li ZH,Zhao L,He YN

更新日期：2012-07-12 00:00:00

abstract：:In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, further complicated by limited therapeutic options and inconsistent follow up. The consequences are ...

journal_title：Cardiovascular journal of Africa

authors： Meyer PW,Anderson R,Ker JA,Ally MT

更新日期：2018-09-01 00:00:00

abstract：:Tricuspid annular ventricular tachycardia (VT) is a rarely encountered entity. Despite abundant data on idiopathic VTs, the prevalence and clinical characteristics of this infrequent form are not well defined and the efficacy of radiofrequency (RF) catheter ablation treatment remains unknown. We report on a case of a ...

journal_title：Cardiovascular journal of Africa

authors： Celik T,Bugan B,Kose S,Yuksel UC,Iyisoy A,Kabul HK,Kursaklioglu H,Isik E

更新日期：2012-07-12 00:00:00

abstract：:Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocard...

journal_title：Cardiovascular journal of Africa

authors： McCutcheon K,Manga P

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:We explored the association of N-terminal probrain natriuretic peptide (NT-proBNP) with metabolic traits in a bi-ethnic African-Caucasian cohort. METHODS:Baseline examinations of the Sympathetic activity and Ambulatory Blood Pressure in African (SABPA) prospective cohort study were performed between 2008 an...

journal_title：Cardiovascular journal of Africa

authors： Jujić A,Melander O,Nilsson PM,Malan L,Fedorowski A,Magnusson M

更新日期：2020-11-01 00:00:00

abstract：:Takotsubo cardiomyopathy (TCMP) is characterised by a temporary aneurysm of the left ventricular apex in individuals without significant stenosis of the coronary arteries. It is extremely rare to see it combined with a thrombus. In this case report, we present a 57-year-old female patient with TCMP in whom apical thro...

journal_title：Cardiovascular journal of Africa

authors： Icli A,Akilli H,Kayrak M,Aribas A,Ozdemir K

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) has been the leading cause of death in developed countries for most of the last century. Most CVD deaths, however, occur in low- and middle-income, developing countries (LMICs) and there is great concern that CVD mortality and burden are rapidly increasing in LMICs as a result of...

journal_title：Cardiovascular journal of Africa

authors： Mensah GA,Roth GA,Sampson UK,Moran AE,Feigin VL,Forouzanfar MH,Naghavi M,Murray CJ,GBD 2013 Mortality and Causes of Death Collaborators.

更新日期：2015-03-01 00:00:00