Rheumatoid arthritis and risk of cardiovascular disease.

Abstract:

:In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, further complicated by limited therapeutic options and inconsistent follow up. The consequences are often severe with irreversible disability, increased frequency of co-morbidities, especially cardiovascular disease (CVD), and higher mortality rates, relative to developed countries. Despite addressing traditional cardiovascular risk factors, the impact of subclinical or 'residual' inflammation from uncontrolled RA needs to be considered. This narrative review explores the prevalence and pathogenesis of CVD in RA, including the impact of tobacco use. It discusses pitfalls in the risk assessment of CVD in patients with RA, and the effect of disease-modifying anti-rheumatic therapy on cardiovascular co-morbidity.

journal_name

Cardiovasc J Afr

authors

Meyer PW,Anderson R,Ker JA,Ally MT

doi

10.5830/CVJA-2018-018

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

317-321

issue

5

eissn

1995-1892

issn

1680-0745

journal_volume

29

pub_type

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