Abstract:
OBJECTIVE:Few data are available on heart failure (HF) in sub-Saharan Africa. We aimed to provide a current picture of HF aetiologies in urban Uganda, access to heart surgery, and outcomes. METHODS:We prospectively collected clinical and echocardiographic data from 272 consecutive patients referred for suspected heart disease to a tertiary hospital in Kampala during seven non-governmental organisation (NGO) missions from 2009 to 2013. We focused the analysis on 140 patients who fulfilled standardised criteria of HF by echocardiography. RESULTS:Rheumatic heart disease (RHD) was the leading cause of HF in 44 (31%) patients. Among the 50 children included (age ≤ 16 years), congenital heart disease (CHD) was the first cause of HF (30 patients, 60%), followed by RHD (16 patients, 32%). RHD was the main cause of HF (30%) among the 90 adults. All 85 patients with RHD and CHD presented with an indication for heart surgery, of which 74 patients were deemed fit for intervention. Surgery was scheduled in 38 patients with RHD [86%, median age 19 years (IQR: 12-31)] and in 36 patients with CHD [88%, median age 4 years (IQR 1-5)]. Twenty-seven candidates (32%) were operated on after a median waiting time of 10 months (IQR 6-21). Sixteen (19%) had died after a median of 38 months (IQR 5-52); 19 (22%) were lost to follow up. CONCLUSION:RHD still represents the leading cause of HF in Uganda, in spite of cost-efficient prevention strategies. The majority of surgical candidates, albeit young, do not have access to treatment and present high mortality rates.
journal_name
Cardiovasc J Afrjournal_title
Cardiovascular journal of Africaauthors
Grimaldi A,Ammirati E,Karam N,Vermi AC,de Concilio A,Trucco G,Aloi F,Arioli F,Figini F,Ferrarello S,Sacco FM,Grottola R,D'Arbela PG,Alfieri O,Marijon E,Freers J,Mirabel Mdoi
10.5830/CVJA-2014-034subject
Has Abstractpub_date
2014-09-01 00:00:00pages
204-11issue
5eissn
1995-1892issn
1680-0745journal_volume
25pub_type
杂志文章abstract:OBJECTIVES:To assess the influence of diabetes mellitus on early morbidity and mortality following a femoro-popliteal bypass. METHODS:Clinical data on patients subjected to a prosthetic above-the-knee femoro-popliteal bypass for atherothrombotic disease over a four-year period in the Durban Metropolitan Vascular Servi...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract:AIM:Although plasma NT-proBNP differentiates hypertension (HT) with or without left ventricular hypertrophy (LVH) from hypertensive heart failure (HHF), most of the published data are based on studies in Western populations. Also, most previous studies did not consider left ventricular (LV) diastolic function and right...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2014-050
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Previous studies have shown controversial results on the role of androgens in coronary artery disease (CAD). We performed this study to assess the relationship between androgen levels and selective coronary angiography (SCA) findings. METHODS:This study was conducted on 502 consecutive men who underwent SCA...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2007-11-01 00:00:00
abstract:INTRODUCTION:Associations between ambient temperature and blood pressure have been demonstrated in countries where the temperature varies between the seasons. This phenomenon has been overlooked in blood pressure surveys in sub-Saharan Africa. We assessed the effect of ambient temperature on blood pressure in an adult ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::We present a case of the native valve used to complete closure of a ruptured aneurysm of the sinus of Valsalva. Aneurysm of the sinus of Valsalva is rare and a non-coronary artery is affected in only 20% of cases. To close the rupture, we decided to use a non-coronary leaflet in a young patient with moderate aortic st...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
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abstract:AIM:There are few studies to be found in the literature on ankle-brachial index in sickle cell disease. The aim of this study was to compare ankle-brachial index of steadystate adult sickle cell anaemia patients with that of normal controls. METHODS:A descriptive cross-sectional study of 62 sickle cell anaemia patient...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2011-013
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abstract::The year 2011 marks the 30th anniversary of the founding of the Pan-African Society of Cardiology (PASCAR). Throughout its brief history, PASCAR has been integral to improving the cardiovascular health of the people of Africa. During the past three decades, many African countries have been vulnerable to political and ...
journal_title:Cardiovascular journal of Africa
pub_type: 社论,历史文章
doi:
更新日期:2011-05-01 00:00:00
abstract:INTRODUCTION:This prospective study was planned to investigate the frequency and relationship of acquired von Willebrand syndrome (AVWS) with aortic and pulmonary stenosis in patients. METHODS:A total of 84 children, ranging from two to 18 years of age, were enrolled in this study. Of these, 28 had isolated aortic ste...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2015-048
更新日期:2015-07-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2014-003
更新日期:2014-03-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,评审
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更新日期:2017-11-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2016-083
更新日期:2017-07-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2011-051
更新日期:2012-06-12 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,评审
doi:10.5830/CVJA-2018-042
更新日期:2019-01-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2018-028
更新日期:2018-07-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2018-036
更新日期:2018-09-01 00:00:00
abstract::Cardiovascular disease (CVD) is the frontrunner in the disease spectrum of sub-Saharan Africa, with stroke and ischaemic heart disease ranked seventh and 14th as leading causes of death, respectively, on this sub-continent. Unfortunately, this region is also grappling with many communicable, maternal, neonatal and nut...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,评审
doi:10.5830/CVJA-2016-082
更新日期:2017-07-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2015-056
更新日期:2016-05-01 00:00:00
abstract::Left ventricular hypertrophy is a common complication of primary hyperparathyroidism. Numerous disturbances of myocardial physiology have been described as a result of excess parathyroid hormone action. In this brief communication, another phenotype of the hyperparathyroid heart is proposed, the 'pseudo-myocardial inf...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract::We present the case of a 57-year-old female who experienced iatrogenic left main-stem (LMS) dissection during elective coronary angiography. The dissection immediately affected the circumflex artery (Cx), causing its total distal occlusion, and the left anterior descending artery (LAD), in which a metal stent, implant...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2015-060
更新日期:2015-11-23 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2013-003
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,评审
doi:10.5830/CVJA-2018-018
更新日期:2018-09-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2011-069
更新日期:2012-07-12 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type:
doi:10.5830/CVJA-2020-058
更新日期:2021-01-15 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::Acute myocardial infarction is a rare complication of dobutamine stress echocardiography. We describe the case of a diabetic patient who presented with an anterior myocardial infarction complicated by an acute pulmonary oedema and cardiogenic collapse during dobutamine stress echocardiography, requiring five days' hos...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2013-021
更新日期:2013-06-23 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,评审
doi:
更新日期:2007-07-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,评审
doi:10.5830/CVJA-2015-087
更新日期:2016-03-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2016-038
更新日期:2016-11-01 00:00:00