The differential effects of FTY720 on functional recovery and infarct size following myocardial ischaemia/reperfusion.

abstract：BACKGROUND:Methods of closing patent ductus arteriosus (PDA) have evolved over time. We review this development in our setting. METHODS:This was a retrospective analysis of children who had transcatheter PDA closure at Chris Hani Baragwanath Hospital between 1993 and 2008. RESULTS:Over 15 years, 1 254 PDAs were diagn...

journal_title：Cardiovascular journal of Africa

authors： Adams PE,Chersich MF,Cilliers A

更新日期：2018-07-01 00:00:00

abstract：AIM:There are few studies to be found in the literature on ankle-brachial index in sickle cell disease. The aim of this study was to compare ankle-brachial index of steadystate adult sickle cell anaemia patients with that of normal controls. METHODS:A descriptive cross-sectional study of 62 sickle cell anaemia patient...

journal_title：Cardiovascular journal of Africa

authors： Oguanobi NI,Onwubere BJ,Ibegbulam OG,Ike SO,Ejim EC,Agwu O

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:We aimed to determine the possible factors leading to re-operation in patients undergoing mechanical valve replacement and to investigate the relationship between valvular thrombus formation and mean platelet volume. METHODS:The medical records of 43 patients with mechanical valve implantation, who were adm...

journal_title：Cardiovascular journal of Africa

authors： Aydin E,Yapici F

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Paediatric cardiac services in Nigeria have been perceived to be inadequate but no formal documentation of availability and distribution of facilities and services has been done. OBJECTIVE:To evaluate and document the currently available paediatric cardiac services in Nigeria. METHODS:In this questionnaire...

journal_title：Cardiovascular journal of Africa

authors： Ekure EN,Sadoh WE,Bode-Thomas F,Orogade AA,Animasahun AB,Ogunkunle OO,Babaniyi I,Anah MU,Otaigbe BE,Olowu A,Okpokowuruk F,Omokhodion SI,Maduka OC,Onakpoya UU,Adiele DK,Sani UM,Asani M,Yilgwan CS,Daniels Q,Uzodimma C

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To identify socio-demographic and lifestyle determinants of weight gain in a sample of premenopasual black South African (SA) women. METHODS:Changes in body composition (dual-energy X-ray absorptiometry, computerised tomography), socio-economic status (SES) and behavioural/lifestyle factors were measured in ...

journal_title：Cardiovascular journal of Africa

authors： Chantler S,Dickie K,Micklesfield LK,Goedecke JH

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality. In the current prospective study, we addressed the impact of RA on left atrial (LA) function and electrical remodelling. Further, we tried to demonstrate the effects of infliximab, an anti-TNF-alpha agent, on echoc...

journal_title：Cardiovascular journal of Africa

authors： Çetin S,Mustafa G,Keskin G,Yeter E,Doğan M,Öztürk MA

更新日期：2014-07-01 00:00:00

abstract：:The electrocardiographic term 'pause' refers to the prolonged R-R interval that represents the interruption in ventricular depolarisation. This article presents a case of sinus node dysfunction and provides a diagnostic approach to pauses on the ECG. ...

journal_title：Cardiovascular journal of Africa

authors： Viljoen C,Smith R,Chin A

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Most intra-coronary stents in use are made of 316 L stainless steel, which contains nickel, chromate and molybdenum. Whether inflammatory and allergic reactions to metals contribute to in-stent restenosis is still a matter of debate. AIM:The aim of this study was to ascertain the relationship between metal ...

journal_title：Cardiovascular journal of Africa

authors： Slodownik D,Danenberg C,Merkin D,Swaid F,Moshe S,Ingber A,Lotan H,Durst R

更新日期：2018-01-01 00:00:00

abstract：:Acute myocardial infarction is a rare complication of dobutamine stress echocardiography. We describe the case of a diabetic patient who presented with an anterior myocardial infarction complicated by an acute pulmonary oedema and cardiogenic collapse during dobutamine stress echocardiography, requiring five days' hos...

journal_title：Cardiovascular journal of Africa

authors： Yameogo NV,Mbaye A,Kagambega LJ,Dioum M,Diagne-Sow D,Kane M,Diack B,Kane A

更新日期：2013-06-23 00:00:00

abstract：:Unlike other parts of the world in which cardiomyopathy is rare, heart muscle disease is endemic in Africa. The major forms of cardiomyopathy in Africa are dilated cardiomyopathy (DCM) and endomyocardial fibrosis (EMF). Whereas DCM is a major cause of heart failure throughout the continent, EMF is restricted to the tr...

journal_title：Cardiovascular journal of Africa

authors： Mayosi BM,Somers K

更新日期：2007-05-01 00:00:00

abstract：AIM:To determine whether a single elevated myocardial performance index (MPI) value in the third trimester of pregnancy is a marker for later adverse obstetric outcomes in stable placental-mediated disease, defined as well-controlled pre-eclampsia (PE) on a single agent and/or uncompensated intra-uterine growth restric...

journal_title：Cardiovascular journal of Africa

authors： Bhorat I,Pillay M,Reddy T

更新日期：2018-09-01 00:00:00

abstract：:In this study the baroreflex sensitivity of conscious, juvenile, spontaneously hypertensive rats (SHRs) was compared. The study population consisted of 19 eight-week-old male SHRs. The baroreflex sensitivity was quantified as the derivative of the variation in heart rate (HR) and the variation of mean arterial pressur...

journal_title：Cardiovascular journal of Africa

authors： Valenti VE,De Abreu LC,Colombari E,Sato MA,Ferreira C

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Pulmonary embolism (PE) is a potentially fatal disease. In Angola, few data are available on its occurrence. The aim of the study was to characterise the clinical profile, management and outcomes of patients with PE. METHODS:A retrospective observational study was conducted at the Girassol Clinic in Luanda, ...

journal_title：Cardiovascular journal of Africa

authors： Manuel A,Aufico A,Africano R,Peralta T,Salas A,Silva A,Ricardo J,Sabola P,Baião D,Sotolongo C,Neto AD,Martins T,Sabino V,van Dúnem J,Júnior APF

更新日期：2017-11-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high mo...

journal_title：Cardiovascular journal of Africa

authors： Yolcu M,Gunesdogdu F,Bektas M,Bayirli DT,Serefhanoglu K

更新日期：2020-11-01 00:00:00

abstract：AIM:To investigate the osteogenic differentiation of vascular smooth muscle cells (VSMCs) in mice with chronic kidney disease (CKD) and to evaluate the effects of p53 on the osteogenic differentiation of the VSMCs. METHODS:Experimental models of CKD-associated vascular calcification generated by five-sixth (5/6) nephr...

journal_title：Cardiovascular journal of Africa

authors： Li KL,Chen J,Li ZH,Zhao L,He YN

更新日期：2012-07-12 00:00:00

abstract：:An established relationship exists between human immunodeficiency virus (HIV) and the vascular system, which is characterised by clinical expressions of aneurysmal and occlusive disease that emanate from a common pathological process. The exact pathogenesis is currently unknown; attempts to implicate opportunistic pat...

journal_title：Cardiovascular journal of Africa

authors： Pillay B,Ramdial PK,Naidoo DP

更新日期：2015-03-01 00:00:00

abstract：:Angiogenic imbalance contributes to the development of preeclampsia. We evaluated the protein expression of the proangiogenic placental growth factor (PlGF) and transforming growth factor beta 1 (TGF-β1) compared with the anti-angiogenic soluble fms-like tyrosine kinase receptor (sFlt1) and soluble endoglin (sEng) in ...

journal_title：Cardiovascular journal of Africa

authors： Govender N,Naicker T,Moodley J

更新日期：2013-06-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is a relatively common arrhythmia. When AF represents an electrophysiological phenomenon in structurally normal hearts, it is termed lone AF. This study was a retrospective, case-based analysis of patients attending the Cardiac Clinic at Groote Schuur Hospital (GSH) and describes t...

journal_title：Cardiovascular journal of Africa

authors： Thomas V,Schulein S,Millar RN,Mayosi BM

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Guidelines advise early angiography in non-ST elevation myocardial infarction (NSTEMI) to ensure an optimal outcome. Resource limitations in secondary hospitals in the Western Cape dictate a local guideline to treat NSTEMIs medically with out-patient assessment for angiography, unless mandatory indications f...

journal_title：Cardiovascular journal of Africa

authors： Moses J,Doubell AF,Herbst PG,Klusmann KJ,Weich HS

更新日期：2013-05-01 00:00:00

abstract：:Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocard...

journal_title：Cardiovascular journal of Africa

authors： McCutcheon K,Manga P

更新日期：2018-01-01 00:00:00

abstract：:Levosimendan was developed as a treatment for acute decompensation of severe heart failure (HF). Its use has evolved during recent years, and new HF treatment strategies in different settings have been developed. This case series aimed to show indications for the use of levosimendan and to discuss the treatment respon...

journal_title：Cardiovascular journal of Africa

authors： Wawrzyniak M,Migaj J,Straburzyńska-Migaj E,Dudek M,Kałużna-Oleksy M

更新日期：2021-01-15 00:00:00

abstract：:This study examined the effects of quercetin on spontaneously contracting portal veins isolated from healthy young adult male and female Wistar rats (250-300 g). Quercetin (10(-7)-10(-4) M) always produced significant biphasic effects, comprising an initial brief stimulant effect (rise in basal tone), followed by a su...

journal_title：Cardiovascular journal of Africa

authors： Chiwororo WD,Ojewole JA

更新日期：2010-05-01 00:00:00

abstract：:Risk models are widely used to predict outcomes after cardiac surgery. Not only is risk modelling applied in the assessment of the relative impact of specific risk factors on surgical outcomes, but also in patient counselling, the selection of treatment options, comparison of postoperative results, and quality-improve...

journal_title：Cardiovascular journal of Africa

authors： Prins C,de Villiers Jonker I,Botes L,Smit FE

更新日期：2012-04-01 00:00:00

abstract：:The Fontan operation is the primary surgical technique used for palliation of patients with single-ventricle physiology. Arrhythmias are frequently observed and associated with morbidity and mortality in Fontan patients. The frequency of arrhythmias after the Fontan procedure increases over time and it was reported to...

journal_title：Cardiovascular journal of Africa

authors： Agir AA,Celikyurt U,Karauzum K,Yilmaz I,Ozbudak E,Bozyel S,Kanko M,Vural A,Ural D

更新日期：2014-11-23 00:00:00

abstract：BACKGROUND:Dyslipidaemia is a major modifiable risk factor for atherosclerotic cardiovascular disease. At the time the study was conducted, guidelines recommended a low-density lipoprotein cholesterol (LDL-C) target of less than 1.8 mmol/l and a reduction of at least 50% if the baseline LDL-C was between 1.8 and 3.5 mm...

journal_title：Cardiovascular journal of Africa

authors： Blom DJ,Ranjith N,Joshi P,Naidoo P,van Tonder A,Musa MG,Joshi S,Leisegang R,Trokis JS,Makan H,Raal FJ

更新日期：2020-09-01 00:00:00

abstract：:Optimal maternal body composition during pregnancy is a public health priority due to its implications on maternal health and infant development. We therefore aimed to conduct a systematic review of randomised, controlled trials, and case-control and cohort studies using lifestyle interventions to improve body composi...

journal_title：Cardiovascular journal of Africa

authors： Watson ED,Macaulay S,Lamont K,Gradidge PJ,Pretorius S,Crowther NJ,Libhaber E

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that the Tp-e interval, which on an electrocardiogram (ECG) is the interval between the peak and the end of the T wave, can be used as an index of transmural dispersion of ventricular repolarisation (TDR). Both Tp-e/QT and Tp-e/QTc ratios have also been used in that capacity. Howeve...

journal_title：Cardiovascular journal of Africa

authors： Kucuk M,Karadeniz C,Ozdemir R,Meşe T

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:Little is known about the performance of re-used pacemakers and implantable cardioverter defibrillators (ICDs) in Africa. We sought to compare the risk of infection and the rate of malfunction of re-used pacemakers and ICDs with new devices implanted at Groote Schuur Hospital in Cape Town, South Africa. MET...

journal_title：Cardiovascular journal of Africa

authors： Jama ZV,Chin A,Badri M,Mayosi BM

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The South African National Development Plan (SANDP) vision for 2030 highlights key recommendations for reducing the prevalence of non-communicable diseases (NCDs) by 28% by 2030. These are mirrored by the World Heart Federation, although it focuses on reducing the NCD prevalence by 25% by 2025. The targeted ...

journal_title：Cardiovascular journal of Africa

authors： Siweya H,Monyeki KD

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Hypertension is a common cardiovascular disease, affecting adults worldwide and it accounts for up to 30% of all deaths. The need for better control of arterial hypertension justifies observational studies designed to better understand the real-life management of hypertensive patients. The ASTRAL study was p...

journal_title：Cardiovascular journal of Africa

authors： Okpechi IG,Schoeman HS,Longo-Mbenza B,Oke DA,Kingue S,Nkoua JL,Rayner BL

更新日期：2011-03-01 00:00:00