Abstract:
BACKGROUND:We aimed to determine the possible factors leading to re-operation in patients undergoing mechanical valve replacement and to investigate the relationship between valvular thrombus formation and mean platelet volume. METHODS:The medical records of 43 patients with mechanical valve implantation, who were admitted to the Department of Cardiovascular Surgery of Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital between 2000 and 2005 were analysed retrospectively. Data recorded included demographic characteristics, valve type, size and location, implantation position, warfarin use, INR level, additional cardiac intervention, presence of left atrial thrombus, valvular thrombus, pannus formation, perivalvular leak, left atrial aneurysm, platelet count and mean platelet volume (MPV), bleeding after the primary surgery and/or revision of surgery due to other reasons, valve protection, aortic root expansion, presence of valve calcification and infective endocarditis, pre- and postoperative rhythm pattern, brand name of prosthesis, distance of the patient's house from a cardiac surgery centre, and concomitant noncardiac systemic diseases. RESULTS:Mean age was 49.3 years (range 19-78 years). Of the patients, 51% (n = 22) were males and 49% (n = 21) were females. The re-operation mortality was 11.6%. Age, gender, valve type, brand of valve prosthesis, and implantation position were not risk factors for re-operation. The MPV was higher and statistically significant in patients with valvular thrombus during re-operation (p < 0.001). MPV was determined to be an independent risk factor with 85% sensitivity and 87% specificity. CONCLUSION:MPV and INR levels should be closely monitored when designing individualised postoperative medical treatment for patients undergoing heart valve re-operation.
journal_name
Cardiovasc J Afrjournal_title
Cardiovascular journal of Africaauthors
Aydin E,Yapici Fdoi
10.5830/CVJA-2013-044subject
Has Abstractpub_date
2013-08-01 00:00:00pages
251-4issue
7eissn
1995-1892issn
1680-0745journal_volume
24pub_type
杂志文章abstract::Acute type II aortic dissection and aortic coarctation are rare combined disorders. This report is of a patient with coarctation, a bicuspid aortic valve and type II dissection, who underwent emergency repair for the dissection, with aortic valve preservation. Repair of the coarctation was planned for a future occasio...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2013-064
更新日期:2013-09-23 00:00:00
abstract:OBJECTIVES:Little is known about the performance of re-used pacemakers and implantable cardioverter defibrillators (ICDs) in Africa. We sought to compare the risk of infection and the rate of malfunction of re-used pacemakers and ICDs with new devices implanted at Groote Schuur Hospital in Cape Town, South Africa. MET...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2015-048
更新日期:2015-07-01 00:00:00
abstract::Takotsubo cardiomyopathy (TCMP) is characterised by a temporary aneurysm of the left ventricular apex in individuals without significant stenosis of the coronary arteries. It is extremely rare to see it combined with a thrombus. In this case report, we present a 57-year-old female patient with TCMP in whom apical thro...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2016-011
更新日期:2016-05-01 00:00:00
abstract:AIM:Our aim was to evaluate whether there was a relationship between mean platelet volume and myocardial perfusion defect in diabetic patients using myocardial perfusion imaging. METHODS:Forty-four diabetic patients with myocardial perfusion defect (group 1) and 44 diabetic patients without myocardial perfusion defect...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2014-013
更新日期:2014-05-01 00:00:00
abstract::The electrocardiographic term 'pause' refers to the prolonged R-R interval that represents the interruption in ventricular depolarisation. This article presents a case of sinus node dysfunction and provides a diagnostic approach to pauses on the ECG. ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2017-041
更新日期:2017-07-01 00:00:00
abstract:AIM:Although plasma NT-proBNP differentiates hypertension (HT) with or without left ventricular hypertrophy (LVH) from hypertensive heart failure (HHF), most of the published data are based on studies in Western populations. Also, most previous studies did not consider left ventricular (LV) diastolic function and right...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2014-050
更新日期:2014-09-01 00:00:00
abstract::We are deeply saddened by the loss of our great teacher Donald Ross, a truly global mentor in cardiac surgery, a friend, a respectful colleague, an admirer, and custodian of our profession, who passed away on July 7, 2014. ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2014-07-01 00:00:00
abstract::We present a case of an 85-year-old man with acute myocardial infarction and cardiogenic shock due to left main coronary artery occlusion, with spontaneous dissection of the right coronary artery. ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:CVJ-21.036
更新日期:2011-05-01 00:00:00
abstract::Tricuspid annular ventricular tachycardia (VT) is a rarely encountered entity. Despite abundant data on idiopathic VTs, the prevalence and clinical characteristics of this infrequent form are not well defined and the efficacy of radiofrequency (RF) catheter ablation treatment remains unknown. We report on a case of a ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2012-010
更新日期:2012-07-12 00:00:00
abstract::In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, further complicated by limited therapeutic options and inconsistent follow up. The consequences are ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,评审
doi:10.5830/CVJA-2018-018
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:A four-amino acid deletion was identified within the alpha 2C-adrenergic receptor (alpha 2C Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the alpha 2C Del322-325 polymorphism may be a risk factor for heart fa...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Recent studies have shown that the Tp-e interval, which on an electrocardiogram (ECG) is the interval between the peak and the end of the T wave, can be used as an index of transmural dispersion of ventricular repolarisation (TDR). Both Tp-e/QT and Tp-e/QTc ratios have also been used in that capacity. Howeve...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2018-043
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:Circulatory failure due to acute arterial hypertension in the neonatal period is rare. This study was undertaken to assess the clinical and echocardiographic manifestations of circulatory failure resulting from acute neonatal hypertensive crisis. METHODS:Neonatal and cardiology databases from 2007 to 2010 we...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2013-003
更新日期:2013-04-01 00:00:00
abstract:AIM:There are few studies to be found in the literature on ankle-brachial index in sickle cell disease. The aim of this study was to compare ankle-brachial index of steadystate adult sickle cell anaemia patients with that of normal controls. METHODS:A descriptive cross-sectional study of 62 sickle cell anaemia patient...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2011-013
更新日期:2012-02-01 00:00:00
abstract::Angiogenic imbalance contributes to the development of preeclampsia. We evaluated the protein expression of the proangiogenic placental growth factor (PlGF) and transforming growth factor beta 1 (TGF-β1) compared with the anti-angiogenic soluble fms-like tyrosine kinase receptor (sFlt1) and soluble endoglin (sEng) in ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2013-029
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Although many reports have detailed the advantages and disadvantages between femoral and subclavian arterial cannulations for acute aortic dissection type A (AADA), the confounding factors caused by disease severity and surgical procedures could not be completely eliminated. We compared femoral and subclavia...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2015-056
更新日期:2016-05-01 00:00:00
abstract:AIM:To determine whether a single elevated myocardial performance index (MPI) value in the third trimester of pregnancy is a marker for later adverse obstetric outcomes in stable placental-mediated disease, defined as well-controlled pre-eclampsia (PE) on a single agent and/or uncompensated intra-uterine growth restric...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2018-036
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVES:Few studies have evaluated young adults in their third and fourth decades with coronary artery disease (CAD). This study evaluated the clinical and angiographic profile of young adults ( < 35 years) with CAD. METHODS:A 10-year (2003-2012) retrospective chart review was performed on patients less than 35 yea...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2017-035
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Methods of closing patent ductus arteriosus (PDA) have evolved over time. We review this development in our setting. METHODS:This was a retrospective analysis of children who had transcatheter PDA closure at Chris Hani Baragwanath Hospital between 1993 and 2008. RESULTS:Over 15 years, 1 254 PDAs were diagn...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2018-028
更新日期:2018-07-01 00:00:00
abstract::We report on a patient who developed cardiogenic shock caused by dynamic left ventricular outflow tract (LVOT) obstruction following percutaneous coronary intervention for anteroseptal acute myocardial infarction. ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2010-051
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:Cardiac resynchronisation therapy has been shown to be an effective treatment to improve functional status and prolong survival of patients in advanced chronic heart failure. This study assessed the surgical outcomes of left anterior mini-thoracotomy for the implantation of left ventricular epicardial pacing ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2016-046
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To identify socio-demographic and lifestyle determinants of weight gain in a sample of premenopasual black South African (SA) women. METHODS:Changes in body composition (dual-energy X-ray absorptiometry, computerised tomography), socio-economic status (SES) and behavioural/lifestyle factors were measured in ...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2016-038
更新日期:2016-11-01 00:00:00
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journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::Left ventricular hypertrophy is a common complication of primary hyperparathyroidism. Numerous disturbances of myocardial physiology have been described as a result of excess parathyroid hormone action. In this brief communication, another phenotype of the hyperparathyroid heart is proposed, the 'pseudo-myocardial inf...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract::Aneurysms of the left atrial appendage are extremely rare. Enlargement of the left atrial appendage can be congenital or acquired. Dysplasia of the left atrial muscles leads to congenital left atrial appendage aneurysm and usually presents as atrial tachyarrhythmia or embolic events in the second or third decade of li...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2011-051
更新日期:2012-06-12 00:00:00
abstract:BACKGROUND:Dyslipidaemia is a major modifiable risk factor for atherosclerotic cardiovascular disease. At the time the study was conducted, guidelines recommended a low-density lipoprotein cholesterol (LDL-C) target of less than 1.8 mmol/l and a reduction of at least 50% if the baseline LDL-C was between 1.8 and 3.5 mm...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,多中心研究
doi:10.5830/CVJA-2020-010
更新日期:2020-09-01 00:00:00
abstract:AIM:It has previously been shown that β-blocker therapy reduces QT dynamics in heart failure patients. The aim of this study was to demonstrate this improvement with the third-generation β-blocker, nebivolol. METHODS:A total of 72 heart failure patients with systolic dysfunction were included in the study. Corrected Q...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2011-046
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Paediatric cardiac services in Nigeria have been perceived to be inadequate but no formal documentation of availability and distribution of facilities and services has been done. OBJECTIVE:To evaluate and document the currently available paediatric cardiac services in Nigeria. METHODS:In this questionnaire...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,多中心研究
doi:10.5830/CVJA-2016-057
更新日期:2017-01-01 00:00:00
abstract::Resistant hypertension is a common clinical problem in South Africa and is frequently associated with low renin and aldosterone levels, especially in black Africans. In South Africa, novel variants in the epithelial sodium channel (ENaC) have been described to be associated with varying degrees of hypokalaemia and hyp...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章
doi:10.5830/CVJA-2017-012
更新日期:2017-09-23 00:00:00
abstract::Pulmonary hypertension (PH) has progressively moved from an orphan disease to a significant global health problem with a major disease burden in limited7hyphen;resource countries, where over 97% of patients live. The aetiologies of PH differ between high- and low-income nations, but PH due to left heart disease is cre...
journal_title:Cardiovascular journal of Africa
pub_type: 杂志文章,评审
doi:10.5830/CVJA-2018-042
更新日期:2019-01-01 00:00:00