Abstract：
:Castleman's disease (CD) is a polyclonal lymphoproliferative disorder also known as giant nodular hyperplasia or angiofollicular lymph node hyperplasia. It is a rare disease often associated to human immunodeficiency virus (HIV) and human herpes virus 8 (HHV-8). Histopathological findings in Castleman's disease suggest an exaggerated response to antigenic stimuli seen in other diseases associated with immune activation, such as rheumatoid arthritis. An important aspect of its pathogenesis is the autonomous production of interleukin-6 (IL-6). In this disease, the clinical manifestations are associated to IL-6 serum levels, and surgical removal of the compromised lymph nodes or use of anti-IL-6 antibodies can slow down the symptoms. We describe a multicentric Castleman's disease in a young woman not associated to HHV-8 virus infection or immunosuppression. A short review of the literature follows the description of this clinical case.
journal_name
Rev Bras Reumatoljournal_title
Revista brasileira de reumatologiaauthors
Forteski Dde F,Netto FC,Lomonte AB,dos Anjos BC,Zerbini MC,Zerbini CAdoi
10.1016/j.rbr.2013.05.004subject
Has Abstractpub_date
2014-07-01 00:00:00pages
326-9issue
4eissn
0482-5004issn
1809-4570pii
S0482-5004(14)00127-2journal_volume
54pub_type
杂志文章abstract：:Idiopathic chondrolysis of the hip is a rare condition of unknown etiology characterized by progressive destruction of the hyaline cartilage that covers the femoral head and acetabulum. Idiopathic chondrolysis of the hip has an insidious beginning and affects more often female adolescents. Patients report severe hip p...
journal_title：Revista brasileira de reumatologia
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doi：
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the use of the spectral Doppler (SDoppler) to quantify inflammatory activity and to detect nail echotextural differences in patients with psoriatic arthritis and onychomycosis. METHODS:Two patients, one with psoriatic arthritis but with no joint pain nor nail clinical change and the other with on...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2014.03.029
更新日期：2014-11-01 00:00:00
abstract：:Systemic lupus erythematosus juvenile (SLEJ) is a multi-systemic, chronic inflammatory disease, and with autoimmune features. Some clinical manifestations of this disease are similar to those found in Acquired Immunodeficiency Syndrome (AIDS). Coexistence of AIDS with SLEJ is rare, especially in the pediatric populati...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
abstract：:Over the past decades, the role of exercise training in rheumatic diseases has been largely explored. Currently, physical activity is well known to benefit patients with osteoporosis, osteoarthritis, systemic lupus erythematosus, systemic sclerosis, idiopathic inflammatory myopathy, fibromyalgia and rheumatoid arthrit...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-09-01 00:00:00
abstract：:Spondyloarthritis patients can be more frequently affected by IgA nephropathy than the general population, and a common etiopathogenic mechanism can be involved. We report four cases that may exemplify that association. ...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:Rheumatoid arthritis (RA) is a chronic systemic and progressive inflammatory disorder of the joints, which can result in deformity and functional disability. The diagnosis, treatment, and follow-up of patients with RA vary worldwide. The major societies of rheumatology, as well as governmental agencies in ...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2011-05-01 00:00:00
abstract：INTRODUCTION:Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic joint inflammation that often leads to significant disability. Several effective anti-TNF agents have been used, but some patients have shown an inadequate response. Rituximab is a therapeutic monoclonal antibody indicated ...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章,评审
doi：
更新日期：2014-05-01 00:00:00
abstract：INTRODUCTION:Osteoarthritis (OA) affects the articular cartilage and subchondral bone, compromising the joint as a whole. The knee joint is characterized as one of the main sites of involvement of OA and the most significant risk factors for developing the disease are aging, overweight and female gender. OA is consider...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2015.03.001
更新日期：2015-09-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2014.08.014
更新日期：2015-03-01 00:00:00
abstract：:Rats are currently the most used laboratory animals to investigate osteoporosis. We report an efficient method of ovariectomy and compared this method with the two other operative methods of ovariectomy (i.e., midline dorsal skin incision and double dorsolateral approach, which are used commonly for inducing experimen...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2012-05-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2010-11-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2014.12.016
更新日期：2015-05-28 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1590/s0482-50042010000500007
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION:TCF7L2 is a transcription factor involved in Wnt/beta-catenin signaling and which has a variant known to be consistently associated with type 2 diabetes risk and some studies have also indicated its association with risk of certain types of cancer. OBJECTIVE:Since this pathway may be involved in the patho...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2012-08-01 00:00:00
abstract：:Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine, and its excess can lead to severe consequences. Those effects are known to be antagonized by TNF-alpha inhibitors. Etanercept is a fusion protein that inhibits TNF-alpha action. As TNF-alpha regulation is related to cellular differentiation of vari...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:To translate and validate the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST 2.0) into Brazilian Portuguese. METHODS:Certified translators translated and back-translated Quest. Content validity (CVI) was determined by 5 experts and, after the final version of B-Quest, a pre-test was ...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2014.04.003
更新日期：2014-07-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2014.04.001
更新日期：2014-09-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：INTRODUCTION:The Brazilian Unified Health Care System (SUS) offers treatment for patients with RA through federal funding (Ministry of Health) and state co-financing. The Clinical Protocol and Therapeutic Guidelines for the treatment of rheumatoid arthritis describe the therapeutic regimen for the disease, including th...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2015.11.004
更新日期：2016-03-08 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2013-05-01 00:00:00
abstract：:This is a case report of juvenile idiopathic arthritis (JIA) in two pairs of brothers followed in the department of pediatric rheumatology, Universidade Federal da Bahia. Genetic involvement in JIA pathogenesis is clear and the risk of recurrence among siblings supports this contribution. An important landmark of this...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2013.05.006
更新日期：2015-01-01 00:00:00
abstract：UNLABELLED:While reaffirming that the clinical exam still is the best medical practice, the author has proposed a new maneuver (Cecin's sign or "X" sign) to help the diagnosis of herniated lumbar disk, describing its biomechanical bases. However, the diagnostic performance of this maneuver has not been formally tested....
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章,评审
doi：
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVE:To analyze the frequency of psychiatric comorbidities in patients with systemic lupus erythematosus (SLE) using the systematic review method. METHODS:A systematic literature search was performed between April and July 2011 in the following databases: BIREME, PubMed and CAPES thesis database. This search prio...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
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journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：10.1016/j.rbr.2014.12.002
更新日期：2015-07-01 00:00:00
abstract：:Ankylosing spondylitis (AS) is a chronic rheumatic disease of young men that affects mainly the axial skeleton and is associated with HLA-B27 in 90% of the cases. Incidence of cardiovascular involvement in AS ranges between 10%-30%; conduction disturbances have been described in 1%-9% of the patients with AS. The majo...
journal_title：Revista brasileira de reumatologia
pub_type： 杂志文章
doi：
更新日期：2012-10-01 00:00:00
