Abstract：
:Implant fixation implies a strong and durable mechanical bond between the prosthetic component and host skeleton. Assuming the short-term impediments to implant fixation are successfully addressed and that longer-term issues such as late infection and mechanical failure of the components are avoided, the biological response of the host tissue to the presence of the implant is critical to long-term success. In particular, maintenance of adequate peri-prosthetic bone stock is a key factor. Two major causes of bone loss in the supporting bone are adverse bone remodeling in response to debris shed from the implant and stress-shielding. Here, I review some of the major lessons learned from studying stress-shielding-induced bone loss. It is well known that stress-shielding can be manipulated by altering implant design, but less well appreciated that the development of bone anabolic agents may make it possible to reduce the severity of stress-shielding and the associated bone loss by augmenting the host skeleton through the use of locally or systemically delivered agents. In most cases, mechanical, material and biological factors do not act in isolation, emphasizing that it is often not possible to optimize all boundary conditions.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Sumner DRdoi
10.1016/j.jbiomech.2014.12.021subject
Has Abstractpub_date
2015-03-18 00:00:00pages
797-800issue
5eissn
0021-9290issn
1873-2380pii
S0021-9290(14)00675-7journal_volume
48pub_type
杂志文章,评审abstract：:The objective of this study was to examine the use of the continuous wavelet transform (CWT) on surface electromyographic (sEMG) signals acquired from the lower extremity muscles during gait in children with typical development (TD) and cerebral palsy (CP). This was done to explore the possibility of developing a quan...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2004.07.002
更新日期：2005-06-01 00:00:00
abstract：:The influence of ankle kinematics and plantar pressure from mid-range barefoot running on T2 relaxation times of tibiotalar cartilage is unknown. This study aimed to quantitatively evaluate the T2 relaxation time of tibiotalar cartilage and ankle biomechanics following 5 km barefoot running. Twenty healthy runners (wh...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.04.046
更新日期：2019-06-11 00:00:00
abstract：:Intravesical and urethral pressure signals during cough and Valsalva maneuvers for 15 continent women were analyzed with frequency spectrum analysis. Clear modulation of the urethral pressure changes by the intravesical pressure rise during stress maneuvers was demonstrated in the frequency bands of 14 and 7 Hz for co...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(01)00006-9
更新日期：2001-05-01 00:00:00
abstract：:Motion capture systems currently used in biomechanical analysis introduce systematic measurement errors that appear in the form of noise in recorded displacement signals. The noise is unacceptably amplified when differentiating displacements to obtain velocities and accelerations. To avoid this phenomenon, it is neces...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2004.05.031
更新日期：2005-05-01 00:00:00
abstract：:Although numerous studies have addressed the effects of ACL injury and reconstruction on knee joint motion, there is currently little data available describing in vivo ACL strain during activities of daily living. Data describing in vivo ACL strain during activities such as gait is critical to understanding the biomec...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2012.10.031
更新日期：2013-02-01 00:00:00
abstract：:Prolonged mechanical loading of soft tissues adjacent to bony prominences can lead to degeneration of muscle tissue, resulting in a condition termed pressure-related deep tissue injury. This type of deep pressure ulcers can develop into a severe wound, associated with problematic healing and a variable prognosis. Limi...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.09.016
更新日期：2008-12-05 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(95)00086-0
更新日期：1996-05-01 00:00:00
abstract：:Subchondral bone microdamage due to high-impact loading is a key factor leading to post-traumatic knee osteoarthritis. A quantified assessment of the mechanical characteristics of subchondral bone at the tissue-level is essential to study the mechanism of impact-induced microdamage. We combined mechanical impact testi...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.05.016
更新日期：2016-07-05 00:00:00
abstract：:Considerable forces and moments act at hip prostheses during most kinds of physical activities. High torque around the stem axis may contribute to implant loosening. With instrumented hip prostheses the joint force and its direction, the bending moment in the frontal plane and the torque were measured in two patients ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)00105-d
更新日期：1995-05-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(84)90101-5
更新日期：1984-01-01 00:00:00
abstract：:Experimental tests, such as the confined and unconfined compression and the indentation tests, are traditionally used to determine the poroelastic properties of hydrated soft tissues (HSTs). The purpose of this study was to quantitatively evaluate the reliability of H(A) and K values as identified from experimental co...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.02.020
更新日期：2007-01-01 00:00:00
abstract：:The mechanical effects of varying the depth of cement penetration in the cement-bone interface were investigated using finite element analysis (FEA) and validated using companion experimental data. Two FEA models of the cement-bone interface were created from micro-computed tomography data and the penetration of cemen...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.11.033
更新日期：2010-04-19 00:00:00
abstract：:Physical activity in children is important as it leads to healthy growth due to physiological benefits. However, a physiological benefit can be partially negated by excessive or unphysiological loads within the joints. To gain an initial understanding into this, the present study sought to compare joint loading betwee...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.01.051
更新日期：2019-04-18 00:00:00
abstract：:Artery bent buckling has been suggested as a possible mechanism that leads to artery tortuosity, which is associated with aging, hypertension, atherosclerosis, and other pathological conditions. It is necessary to understand the relationship between microscopic wall structural changes and macroscopic artery buckling b...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.06.005
更新日期：2014-08-22 00:00:00
abstract：:This paper deals with the impact force during foot-ground impact activities such as the running. A previously developed model is used for this study. The model is a lumped-parameter one consisting of four masses connected to each other via linear springs and viscous dampers. A shoe-specific nonlinear function is used ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2006.09.016
更新日期：2007-01-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.10.037
更新日期：2007-01-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109980
更新日期：2020-09-18 00:00:00
abstract：:A general theory is described for deriving the mechanical effect of muscles with large attachment sites. In a cadaver experiment the complete attachment sites and bundle distribution of 16 muscles of the shoulder mechanism were recorded. These data were used to calculate the mechanical effect, i.e. the resulting force...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(91)90007-a
更新日期：1991-01-01 00:00:00
abstract：:A three-dimensional, mathematical model of the elbow and wrist joints, including 15 muscle units, 3 ligaments and 4 joint forces, has been developed. A new strain gauge transducer has been developed to measure functional grip forces. The device measures radial forces divided into six components and forces of up to 250...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00184-0
更新日期：2000-05-01 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.06.017
更新日期：2014-09-22 00:00:00
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journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2012.10.016
更新日期：2013-02-01 00:00:00
abstract：:Inertial measurement units (IMUs) offer great opportunities to analyze segmental and joints kinematics. When combined with another motion capture system (MCS), for example, to validate new IMU-based applications or to develop mixed systems, it is necessary to align the local frame of the IMU sensors to the local frame...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2012.06.009
更新日期：2012-08-31 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(89)90019-5
更新日期：1989-01-01 00:00:00
abstract：:Studies of proximal femoral strength usually involve one of two types of loading conditions, loading similar to joint loading during single-limb stance or loading simulating impact from a fall. When interpreting the results of studies involving only one of these load configurations, the question arises as to their app...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00202-x
更新日期：2000-04-01 00:00:00
abstract：:Hyperelastic material models have been incorporated in the rotation-free, large deformation, shell finite element (FE) formulation of (Stolarski et al., 2013) and applied to dynamic simulations of aortic heart valve. Two models used in the past in analysis of such problem i.e. the Saint-Venant and May-Newmann-Yin (MNY...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.11.031
更新日期：2017-01-04 00:00:00
abstract：:Uniaxial tensile tests are commonly used to characterize the structural and material properties of tendons and ligaments. During these tests, the stress and strain distributions applied to the specimen are assumed to be uniform. However, few studies have investigated the strain distributions throughout the tissue. The...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2004.12.021
更新日期：2006-01-01 00:00:00
abstract：:The fluid-structure interaction and energy transfer from respiratory airflow to self-sustained vocal fold oscillation continues to be a topic of interest in vocal fold research. Vocal fold vibration is driven by pressures on the vocal fold surface, which are determined by the shape of the glottis and the contact betwe...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.04.011
更新日期：2018-05-17 00:00:00
abstract：:Static stretching is a major type of mechanical stimuli utilized during distraction osteogenesis (DO), a general surgical method for the lengthening of bone. The molecular signals that drive the regenerative process in DO include a variety of cytokines. Among these, bone morphogenic protein (BMP, -2 and -4) has been r...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.08.006
更新日期：2009-12-11 00:00:00
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journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2006.07.020
更新日期：2007-01-01 00:00:00
abstract：:When recovering balance from a lateral perturbation, younger adults tend to stabilize balance with a single lateral sidestep while older adults often take multistep responses. Using multiple steps to recover balance is consistently associated with increased fall risk, altered body center of mass (CoM) control and inst...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.110161
更新日期：2021-01-04 00:00:00
