Twenty-fold difference in hemodynamic wall shear stress between murine and human aortas.

Abstract:

:Endothelial cells regulate vascular tone and mural remodelling in a shear-dependent manner that is commonly assumed to keep wall shear stress constant across arteries and species. Allometric arguments show that aortic flow velocity is constant across species, a deduction that is consistent with much experimental data, but the same arguments also show that the shear stress experienced by aortic endothelium will depend inversely on body mass to the 3/8th power, and hence will be 20-fold higher in mice than in men. This conclusion is robust and has important implications for the study of shear-dependent vascular biology and pathology.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Weinberg PD,Ross Ethier C

doi

10.1016/j.jbiomech.2006.07.020

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

1594-8

issue

7

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(06)00280-6

journal_volume

40

pub_type

杂志文章
  • Failure of mineralized collagen fibrils: modeling the role of collagen cross-linking.

    abstract::Experimental evidence demonstrates that collagen cross-linking in bone tissue significantly influences its deformation and failure behavior yet difficulties exist in determining the independent biomechanical effects of collagen cross-linking using in vitro and in vivo experiments. The aim of this study is to use a nan...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2008.02.017

    authors: Siegmund T,Allen MR,Burr DB

    更新日期:2008-01-01 00:00:00

  • Dynamics of the human masticatory muscles during a jaw open-close movement.

    abstract::The movements of the human jaw are controlled by the forces produced by the masticatory muscles. As the jaw moves, these muscles change in length and their force producing units, the sarcomeres, change in length simultaneously. The lengths and length changes of the sarcomeres are determinants for the forces they are a...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(97)00047-x

    authors: Koolstra JH,van Eijden TM

    更新日期:1997-09-01 00:00:00

  • Assessment of intersegmental coordination of rats during walking at different speeds - Application of continuous relative phase.

    abstract::The present study investigated the feasibility and reliability of continuous relative phase (CRP) and deviation phase (DP) to assess intersegmental hind limb coordination pattern and coordination variability in rats during walking. Twenty-six adult rats walked at 8 m/min, 12 m/min and 16 m/min while two-dimensional ki...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2018.03.045

    authors: Raffalt PC,Nielsen LR,Madsen S,Højberg LM,Pingel J,Nielsen JB,Alkjær T,Wienecke J

    更新日期:2018-05-17 00:00:00

  • Mechanical properties of rat thoracic and abdominal aortas.

    abstract::Mechanical properties of abdominal and thoracic arteries of 2mm in diameter were determined from adults Wistar rats. A tensile testing instrument was used to obtain stress/strain curves with arteries immersed in physiological buffer at 37 degrees C. A displacement was applied on all arteries with various frequencies (...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2008.04.017

    authors: Assoul N,Flaud P,Chaouat M,Letourneur D,Bataille I

    更新日期:2008-07-19 00:00:00

  • Mechanical characterization of liver capsule through uniaxial quasi-static tensile tests until failure.

    abstract::Accidentology data showed that liver is often injured in car crashes; three types of injuries occur: hematoma, laceration and vessel failure. This paper focuses on surface laceration, which involves liver capsule and hepatic parenchyma. Liver capsule behavior has been studied but its failure properties are still uncle...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2010.03.038

    authors: Brunon A,Bruyère-Garnier K,Coret M

    更新日期:2010-08-10 00:00:00

  • Fluid pressures at the shoe-floor-contaminant interface during slips: effects of tread and implications on slip severity.

    abstract::Previous research on slip and fall accidents has suggested that pressurized fluid between the shoe and floor is responsible for initiating slips yet this effect has not been verified experimentally. This study aimed to (1) measure hydrodynamic pressures during slipping for treaded and untreaded conditions; (2) determi...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jbiomech.2013.10.046

    authors: Beschorner KE,Albert DL,Chambers AJ,Redfern MS

    更新日期:2014-01-22 00:00:00

  • The effect of shortening history on isometric and dynamic muscle function.

    abstract::Despite numerous reports on isometric force depression, few reports have quantified force depression during active muscle shortening (dynamic force depression). The purpose of this investigation was to determine the influence of shortening history on isometric force following active shortening, force during isokinetic...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.10.041

    authors: McDaniel J,Elmer SJ,Martin JC

    更新日期:2010-03-03 00:00:00

  • Simulation of orthotropic microstructure remodelling of cancellous bone.

    abstract::A computational model of adaptive bone remodelling is formulated as an optimization problem of instantaneous changes in microstructure that minimize a functional describing the structure quality rate. Microstructure is locally described by a set of scalar geometric parameters. Macroscopic (continuum) elastic propertie...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2009.09.045

    authors: Kowalczyk P

    更新日期:2010-02-10 00:00:00

  • Changes of opening angle in hypertensive and hypotensive arteries in 3-day organ culture.

    abstract::To study the effect of pressure changes on the opening angle of arteries in organ culture, tubular segments of porcine common carotid arteries were cultured with pulsatile flow perfusion under hypertensive (150+/-20 mmHg), normotensive (100+/-20 mmHg), or hypotensive (30+/-10 mmHg) pressure while maintaining the arter...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2005.08.003

    authors: Han HC,Marita S,Ku DN

    更新日期:2006-01-01 00:00:00

  • The effect of swimming activity on bone architecture in growing rats.

    abstract::The effect of non-habitual physical activity on bone architecture in the rat humeral shaft was examined. Two groups of rats were trained to swim for 1 h a day, for 20 weeks, at two training levels. The control group consisted of sedentary rats. Parameters of cross-sectional bone morphology (cross-section areas, princi...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(89)90068-7

    authors: Simkin A,Leichter I,Swissa A,Samueloff S

    更新日期:1989-01-01 00:00:00

  • Human pendulum approach to simulate and quantify locomotor impact loading.

    abstract::The understanding of impact mechanics during locomotion is important for research within the fields of injury prevention and footwear design. Instrumented missiles offer a worthy solution to the lack of control inherent in in vivo activities and to the isolated nature of tissue studies. However, missiles cannot mimic ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/0021-9290(95)00002-y

    authors: Lafortune MA,Lake MJ

    更新日期:1995-09-01 00:00:00

  • Interlimb coordination in body-weight supported locomotion: A pilot study.

    abstract::Locomotion involves complex neural networks responsible for automatic and volitional actions. During locomotion, motor strategies can rapidly compensate for any obstruction or perturbation that could interfere with forward progression. In this pilot study, we examined the contribution of interlimb pathways for evoking...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.04.042

    authors: Seiterle S,Susko T,Artemiadis PK,Riener R,Igo Krebs H

    更新日期:2015-08-20 00:00:00

  • Ligament fibre recruitment at the human ankle joint complex in passive flexion.

    abstract::Knowledge of ligament fibre recruitment at the human ankle joint complex is a fundamental prerequisite for analysing mobility and stability. Previous experimental and modelling studies have shown that ankle motion must be guided by fibres within the calcaneofibular and tibiocalcaneal ligaments, which remain approximat...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2004.02.043

    authors: Stagni R,Leardini A,Ensini A

    更新日期:2004-12-01 00:00:00

  • Spatial phenotyping of the endocardial endothelium as a function of intracardiac hemodynamic shear stress.

    abstract::Despite substantial evidence for the central role of hemodynamic shear stress in the functional integrity of vascular endothelial cells, hemodynamic and molecular regulation of the endocardial endothelium lining the heart chambers remains understudied. We propose that regional differences in intracardiac hemodynamics ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2016.11.018

    authors: McCormick ME,Manduchi E,Witschey WRT,Gorman RC,Gorman JH 3rd,Jiang YZ,Stoeckert CJ Jr,Barker AJ,Yoon S,Markl M,Davies PF

    更新日期:2017-01-04 00:00:00

  • Structural and mechanical properties of the human Achilles tendon: Sex and strength effects.

    abstract::Tendons are elastic structures that connect muscle to the skeletal system and transmit force relative to the amount of stretch they experience. The mechanical properties of human tendons are difficult to measure non-invasively, so generic values are often assumed in musculoskeletal models to represent all subjects. We...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.06.009

    authors: Morrison SM,Dick TJ,Wakeling JM

    更新日期:2015-09-18 00:00:00

  • A little bit faster: Lower extremity joint kinematics and kinetics as recreational runners achieve faster speeds.

    abstract::There appears a linear relationship between small increases in running speed and cardiovascular health benefits. Encouraging or coaching recreational runners to increase their running speed to derive these health benefits might be more effective if their joint level kinematic and kinetic strategy was understood. The a...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2018.02.010

    authors: Orendurff MS,Kobayashi T,Tulchin-Francis K,Tullock AMH,Villarosa C,Chan C,Kraus E,Strike S

    更新日期:2018-04-11 00:00:00

  • Mathematical model of microbicidal flow dynamics and optimization of rheological properties for intra-vaginal drug delivery: Role of tissue mechanics and fluid rheology.

    abstract::Topically applied microbicide gels can provide a self-administered and effective strategy to prevent sexually transmitted infections (STIs). We have investigated the interplay between vaginal tissue elasticity and the yield-stress of non-Newtonian fluids during microbicide deployment. We have developed a mathematical ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2015.01.049

    authors: Anwar MR,Camarda KV,Kieweg SL

    更新日期:2015-06-25 00:00:00

  • Geometrical resolution limits and detection mechanisms in the oral cavity.

    abstract::The objective of this work is to gain more insight into the processes of oral perception of food texture. Particularly, the limits for detectable thickness differences of objects, which are evaluated in the human mouth, are investigated. In a sensory study small, flexible circular disks (diameter in mm range) of varyi...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2007.04.012

    authors: Strassburg J,Burbidge A,Delgado A,Hartmann C

    更新日期:2007-01-01 00:00:00

  • Effect of cracks on the local deformations of articular cartilage.

    abstract::Despite significant evidence regarding the increased risk of cartilage degeneration due to traumatic injuries to joints, there is still a lack of understanding of the mechanisms underlying osteoarthritis development following a joint injury. Injuries in knee cartilage are often characterized by lesions or tears. In ad...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2020.109970

    authors: Komeili A,Luqman S,Federico S,Herzog W

    更新日期:2020-09-18 00:00:00

  • A new testing device for measuring gliding resistance and work of flexion in a digit.

    abstract::In order to move the finger the tendon force must overcome the gliding resistance of the tendon as well as the forces to move the joints, finger inertias, and external load. These sources, combined, make up the work of flexion (WOF) which has been experimentally used to evaluate the finger function. In this study, we ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(02)00300-7

    authors: Zhao C,Amadio PC,Berglund L,Zobitz ME,An KN

    更新日期:2003-02-01 00:00:00

  • Mechanical properties of human atherosclerotic intima tissue.

    abstract::Progression and rupture of atherosclerotic plaques in coronary and carotid arteries are the key processes underlying myocardial infarctions and strokes. Biomechanical stress analyses to compute mechanical stresses in a plaque can potentially be used to assess plaque vulnerability. The stress analyses strongly rely on ...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbiomech.2014.01.019

    authors: Akyildiz AC,Speelman L,Gijsen FJ

    更新日期:2014-03-03 00:00:00

  • Uncertainty quantification of wall shear stress in intracranial aneurysms using a data-driven statistical model of systemic blood flow variability.

    abstract::Adverse wall shear stress (WSS) patterns are known to play a key role in the localisation, formation, and progression of intracranial aneurysms (IAs). Complex region-specific and time-varying aneurysmal WSS patterns depend both on vascular morphology as well as on variable systemic flow conditions. Computational fluid...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2016.10.005

    authors: Sarrami-Foroushani A,Lassila T,Gooya A,Geers AJ,Frangi AF

    更新日期:2016-12-08 00:00:00

  • A theoretical model of the effect of continuum damage on a bone adaptation model.

    abstract::Throughout life, bone is continuously turning over by the well-regulated processes of bone formation and resorption. Everyday activities damage bone, and this damage is normally repaired in a continuous remodelling process. When an imbalance in this remodelling process occurs, bones may become more susceptible to frac...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(00)00215-3

    authors: Ramtani S,Zidi M

    更新日期:2001-04-01 00:00:00

  • The effects of groove height and substrate stiffness on C. elegans locomotion.

    abstract::The physical environment surrounding an animal has a significant impact on its behavior. The nematode Caenorhabditis elegans (C. elegans) has proved to be an excellent choice for understanding the adaptability of organisms crawling on soft surfaces. In this work, we investigate the modulation of C. elegans' behavioral...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2017.02.015

    authors: Parida L,Ghosh UU,Padmanabhan V

    更新日期:2017-04-11 00:00:00

  • Differences in 3D vs. 2D analysis in lumbar spinal fusion simulations.

    abstract::Lumbar interbody fusion is currently the gold standard in treating patients with disc degeneration or segmental instability. Despite it having been used for several decades, the non-union rate remains high. A failed fusion is frequently attributed to an inadequate mechanical environment after instrumentation. Finite e...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2018.03.009

    authors: Hsu HW,Bashkuev M,Pumberger M,Schmidt H

    更新日期:2018-04-27 00:00:00

  • Quantifying translations in the radiohumeral joint: application of a floating axis analysis.

    abstract::The purpose of this study was to apply the Floating Axis analysis technique to the elbow joint, and to verify its ability to quantify clinically relevant radiohumeral translation in vitro using an electromagnetic tracking device. Of particular interest was the ability to quantify changes in anterior-posterior radial h...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(03)00103-9

    authors: Dunning CE,Duck TR,King GJ,Johnson JA

    更新日期:2003-08-01 00:00:00

  • Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration.

    abstract::Chondrocytes in articular cartilage are regularly subjected to compression and recovery due to dynamic loading of the joint. Previous studies have investigated the elastic and viscoelastic properties of chondrocytes using micropipette aspiration techniques, but in order to calculate cell properties, these studies have...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2004.11.006

    authors: Trickey WR,Baaijens FP,Laursen TA,Alexopoulos LG,Guilak F

    更新日期:2006-01-01 00:00:00

  • Sensitivity of ACL volume and T2∗ relaxation time to magnetic resonance imaging scan conditions.

    abstract::Anterior cruciate ligament (ACL) volume and T2∗ relaxation times from magnetic resonance (MR) images have been previously shown to predict the structural properties of healing ligaments. We investigated whether MR imaging scan resolution and condition (in vivo, in situ, or ex vivo) affected ACL volume and T2∗ relaxati...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2017.03.010

    authors: Beveridge JE,Walsh EG,Murray MM,Fleming BC

    更新日期:2017-05-03 00:00:00

  • The consequences of dehydration-hydration on bone anisotropy and implications on the sublamellar organization of mineralized collagen fibrils.

    abstract::In this study, the effect of dehydration-hydration based sublamellar dimensional change on bone anisotropy was used as a tool to understand sublamellar organization of mineralized collagen fibrils. Bone consists of hydroxyapatite, Type I Collagen, mucopolysaccharides and bone fluid, which associates with bone constitu...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/j.jbiomech.2020.109737

    authors: Utku FS

    更新日期:2020-05-07 00:00:00

  • A force transducer to measure individual finger loads during activities of daily living.

    abstract::A new six-degree-of-freedom force transducer has been manufactured, with the sensitivity to measure forces in the range +/-100 N and moments of up to +/-5 Nm. The transducer incorporates two mechanical components: shear forces and bending moments are measured via a strain-gauged tubular section whilst axial forces are...

    journal_title:Journal of biomechanics

    pub_type: 杂志文章

    doi:10.1016/s0021-9290(99)00054-8

    authors: Fowler NK,Nicol AC

    更新日期:1999-07-01 00:00:00